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What Is the Optimal Value of the g-Ratio for Myelinated Fibers in the Rat CNS? A Theoretical Approach

https://doi.org/10.1371/journal.pone.0007754

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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inferredcites →https://doi.org/10.1523/jneurosci.1224-07.2007openalex-snapshot

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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E-jet 3D printed aligned nerve guidance conduits incorporated with decellularized extracellular matrix hydrogel encapsulating extracellular vesicles for peripheral nerve repair

inferred← citeshttps://doi.org/10.1016/j.actbio.2026.01.031openalex-snapshot

Laser patterning of ECM-derived biomaterials to direct degradation, site-specific resorption, controlled vascularization and functional repair of large nerve defects

inferred← citeshttps://doi.org/10.1016/j.archoralbio.2021.105039openalex-snapshot

Environmental enrichment improves hypomyelination, synaptic alterations, and memory deficits caused by tooth loss in aged SAMP8 mice

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2021.05.056openalex-snapshot

Aligned fibrin/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2023.06.015openalex-snapshot

Micro-nanofiber composite biomimetic conduits promote long-gap peripheral nerve regeneration in canine models

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.04.033openalex-snapshot

Engineered nerve guide conduit enhances peripheral nerve regeneration by modulating the microenvironment through macrophage-triggered cascade reactions

inferred← citeshttps://doi.org/10.1016/j.bioactmat.2025.08.018openalex-snapshot

Mesenchymal stem cell-laden double-network hydrogel nerve guidance conduits for peripheral nerve injury repair

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2012.08.018openalex-snapshot

The effect of glycomimetic functionalized collagen on peripheral nerve repair

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.120767openalex-snapshot

Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration

inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.120982openalex-snapshot

Electrical stimulation of human neural stem cells via conductive polymer nerve guides enhances peripheral nerve recovery

inferred← citeshttps://doi.org/10.1016/j.biopsych.2013.03.003openalex-snapshot

Myelin and Axon Abnormalities in Schizophrenia Measured with Magnetic Resonance Imaging Techniques

inferred← citeshttps://doi.org/10.1016/j.biopsych.2022.08.031openalex-snapshot

The Potential of Myelin-Sensitive Imaging: Redefining Spatiotemporal Patterns of Myeloarchitecture

inferred← citeshttps://doi.org/10.1016/j.bja.2018.08.022openalex-snapshot

Dexmedetomidine enhances ropivacaine-induced sciatic nerve injury in diabetic rats

inferred← citeshttps://doi.org/10.1016/j.brainres.2010.06.028openalex-snapshot

Predifferentiated embryonic stem cells promote functional recovery after spinal cord compressive injury

inferred← citeshttps://doi.org/10.1016/j.brainres.2012.09.037openalex-snapshot

Abnormal myelinogenesis in the central nervous system of the VF mutant rat with recoverable tremor

inferred← citeshttps://doi.org/10.1016/j.brainres.2013.06.025openalex-snapshot

Effects of duration and timing of prenatal stress on hippocampal myelination and synaptophysin expression

inferred← citeshttps://doi.org/10.1016/j.brainres.2016.02.015openalex-snapshot

Evolution of rapid nerve conduction

inferred← citeshttps://doi.org/10.1016/j.brainres.2016.09.007openalex-snapshot

Maternal chewing during prenatal stress ameliorates stress-induced hypomyelination, synaptic alterations, and learning impairment in mouse offspring

inferred← citeshttps://doi.org/10.1016/j.brainres.2016.09.021openalex-snapshot

Olfactory ensheathing glia cell therapy and tubular conduit enhance nerve regeneration after mouse sciatic nerve transection

inferred← citeshttps://doi.org/10.1016/j.brainres.2019.146494openalex-snapshot

Mesenchymal stem cells and treadmill training enhance function and promote tissue preservation after spinal cord injury

inferred← citeshttps://doi.org/10.1016/j.brainres.2020.147026openalex-snapshot

Grafts of human adipose-derived stem cells into a biodegradable poly (acid lactic) conduit enhances sciatic nerve regeneration

inferred← citeshttps://doi.org/10.1016/j.brainres.2020.147157openalex-snapshot

Atypical myelinogenesis and reduced axon caliber in the Scn1a variant model of Dravet syndrome: An electron microscopy pilot study of the developing and mature mouse corpus callosum

inferred← citeshttps://doi.org/10.1016/j.brainres.2024.149083openalex-snapshot

Alzheimer’s-linked axonal changes accompany elevated antidromic action potential failure rate in aged mice

inferred← citeshttps://doi.org/10.1016/j.brainresbull.2024.111140openalex-snapshot

Valproic acid ameliorates morpho-dysfunctional effects triggered by Ischiatic nerve crush injury-induced by compression model in mice: Nerve regeneration and immune-modulatory pathway

inferred← citeshttps://doi.org/10.1016/j.brainresbull.2025.111252openalex-snapshot

Addressing myelination disorders: Novel strategies using human 3D peripheral nerve model

inferred← citeshttps://doi.org/10.1016/j.bramec.2024.202483openalex-snapshot

Ultrastructural changes in the striatum of the Slitrk5-/- mouse model of obsessive-compulsive disorder using volume electron microscopy

inferred← citeshttps://doi.org/10.1016/j.cell.2026.01.025openalex-snapshot

Brain-wide mapping of oligodendrocyte organization, oligodendrogenesis, and myelin injury

inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111291openalex-snapshot

A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice

inferred← citeshttps://doi.org/10.1016/j.clim.2013.06.004openalex-snapshot

Early axonal damage and progressive myelin pathology define the kinetics of CNS histopathology in a mouse model of multiple sclerosis

inferred← citeshttps://doi.org/10.1016/j.clim.2013.10.011openalex-snapshot

Differential aspects of immune cell infiltration and neurodegeneration in acute and relapse experimental autoimmune encephalomyelitis

inferred← citeshttps://doi.org/10.1016/j.clim.2015.04.020openalex-snapshot

Four different synthetic peptides of proteolipid protein induce a distinct antibody response in MP4-induced experimental autoimmune encephalomyelitis

inferred← citeshttps://doi.org/10.1016/j.cmpb.2022.106802openalex-snapshot

gACSON software for automated segmentation and morphology analyses of myelinated axons in 3D electron microscopy

inferred← citeshttps://doi.org/10.1016/j.conb.2017.09.014openalex-snapshot

Myelin plasticity and behaviour — connecting the dots

inferred← citeshttps://doi.org/10.1016/j.ejpb.2017.02.007openalex-snapshot

Lidocaine/multivalent ion complex as a potential strategy for prolonged local anesthesia

inferred← citeshttps://doi.org/10.1016/j.exger.2018.05.015openalex-snapshot

Positive changes in femoral nerve morphometry in older rats following aerobic training

inferred← citeshttps://doi.org/10.1016/j.expneurol.2019.113167openalex-snapshot

Intravitreal application of AAV-BDNF or mutant AAV-CRMP2 protects retinal ganglion cells and stabilizes axons and myelin after partial optic nerve injury

inferred← citeshttps://doi.org/10.1016/j.expneurol.2025.115405openalex-snapshot

Sex-dependent impairments in oligodendrocyte maturation and myelination in offspring mice exposed to preeclampsia

inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e14361openalex-snapshot

Development of a new surgical technique to infuse kynurenic acid to optic nerves in chickens for studying loss of myelination

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.05.073openalex-snapshot

Application of electrospun polycaprolactone fibers embedding lignin nanoparticle for peripheral nerve regeneration: In vitro and in vivo study

inferred← citeshttps://doi.org/10.1016/j.ijrobp.2021.08.003openalex-snapshot

Preclinical Risk Evaluation of Normal Tissue Injury With Novel Radiosensitizers

inferred← citeshttps://doi.org/10.1016/j.isci.2026.114808openalex-snapshot

Sphingolipid-neutralizing molecular therapy reduces psychosine cytotoxicity in Krabbe disease

inferred← citeshttps://doi.org/10.1016/j.jasi.2014.09.002openalex-snapshot

Degree of myelination (g-Ratio), Divine proportion and Fibonacci sequence – A mathematical relationship

inferred← citeshttps://doi.org/10.1016/j.jbiomech.2016.11.055openalex-snapshot

Estimating axonal strain and failure following white matter stretch using contactin-associated protein as a fiduciary marker

inferred← citeshttps://doi.org/10.1016/j.jconrel.2016.01.047openalex-snapshot

Hypoxia-specific, VEGF-expressing neural stem cell therapy for safe and effective treatment of neuropathic pain

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2020.122052openalex-snapshot

Notch pathway up-regulation via curcumin mitigates bisphenol-A (BPA) induced alterations in hippocampal oligodendrogenesis

inferred← citeshttps://doi.org/10.1016/j.jmau.2016.02.001openalex-snapshot

Effect of long term-administration of aspartame on the ultrastructure of sciatic nerve

inferred← citeshttps://doi.org/10.1016/j.jneumeth.2020.108990openalex-snapshot

Towards in vivo g-ratio mapping using MRI: Unifying myelin and diffusion imaging

inferred← citeshttps://doi.org/10.1016/j.jneumeth.2022.109663openalex-snapshot

A swim test for functional assessment of rodent peripheral nerve regeneration

inferred← citeshttps://doi.org/10.1016/j.jneuroim.2019.577017openalex-snapshot

Murine cytomegalovirus infection in mice results in an acute inflammatory reaction in peripheral nerves

inferred← citeshttps://doi.org/10.1016/j.jneuroim.2023.578219openalex-snapshot

Inhibition of SUMOylation promotes remyelination and reduces IL-17 mediated autoimmune inflammation: Novel approach toward treatment of inflammatory CNS demyelinating disease

inferred← citeshttps://doi.org/10.1016/j.jns.2014.12.043openalex-snapshot

Morphometric and high resolution scanning electron microscopy analysis of low-level laser therapy and latex protein (Hevea brasiliensis) administration following a crush injury of the sciatic nerve in rats

inferred← citeshttps://doi.org/10.1016/j.jocs.2019.101053openalex-snapshot

Model calibration using a parallel differential evolution algorithm in computational neuroscience: Simulation of stretch induced nerve deficit

inferred← citeshttps://doi.org/10.1016/j.joms.2014.07.009openalex-snapshot

Simultaneous Inferior Alveolar Nerve Regeneration and Osseointegration With a Nerve Growth Factor-Supplying Implant: A Preliminary Study

inferred← citeshttps://doi.org/10.1016/j.joms.2025.05.016openalex-snapshot

Systemic Melatonin Improves Regeneration After Facial Nerve Crush Injury in a Rat Model

inferred← citeshttps://doi.org/10.1016/j.jpain.2021.09.005openalex-snapshot

Neural Recruitment During Conventional, Burst, and 10-kHz Spinal Cord Stimulation for Pain

inferred← citeshttps://doi.org/10.1016/j.jpsychires.2022.09.025openalex-snapshot

Stress-induced myelin damage in the hippocampal formation in a rat model of depression

inferred← citeshttps://doi.org/10.1016/j.jvoice.2021.09.028openalex-snapshot

Morphometric Evaluation of the Recurrent Laryngeal Nerve of Wistar Rats Exposed to Pesticides

inferred← citeshttps://doi.org/10.1016/j.matdes.2025.114931openalex-snapshot

Cod-derived collagen peptides with nerve-regeneration function enable sustained release through 4-Arm PEG hydrogel for peripheral nerve repair

inferred← citeshttps://doi.org/10.1016/j.micron.2010.05.010openalex-snapshot

Transplantation of bone-marrow-derived cells into a nerve guide resulted in transdifferentiation into Schwann cells and effective regeneration of transected mouse sciatic nerve

inferred← citeshttps://doi.org/10.1016/j.micron.2025.103981openalex-snapshot

Morphometric analysis of axonal ultrastructure: Coordinated scaling of organelles and myelin

inferred← citeshttps://doi.org/10.1016/j.mtbio.2026.103411openalex-snapshot

Fuel–maintenance coupling reprograms mitochondrial homeostasis to enable peripheral nerve regeneration

inferred← citeshttps://doi.org/10.1016/j.nbd.2017.04.022openalex-snapshot

Differences in white matter structure between seizure prone (FAST) and seizure resistant (SLOW) rat strains

inferred← citeshttps://doi.org/10.1016/j.neulet.2016.04.006openalex-snapshot

BDNF promotes the axonal regrowth after sciatic nerve crush through intrinsic neuronal capability upregulation and distal portion protection

inferred← citeshttps://doi.org/10.1016/j.neuro.2014.09.005openalex-snapshot

Amelioration of cisplatin-induced experimental peripheral neuropathy by a small molecule targeting p75NTR

inferred← citeshttps://doi.org/10.1016/j.neuro.2018.11.007openalex-snapshot

Carbofuran hampers oligodendrocytes development leading to impaired myelination in the hippocampus of rat brain

inferred← citeshttps://doi.org/10.1016/j.neuro.2025.01.004openalex-snapshot

Therapeutic potential of pranlukast against cuprizone-induced inflammatory demyelination and sensory impairment in mice: Comparison with fingolimod

inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2016.09.016openalex-snapshot

Characterizing axonal myelination within the healthy population: a tract-by-tract mapping of effects of age and gender on the fiber g-ratio

inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2019.03.018openalex-snapshot

Exercise prevents obesity-induced cognitive decline and white matter damage in mice

inferred← citeshttps://doi.org/10.1016/j.neurobiolaging.2024.01.016openalex-snapshot

Volume electron microscopy reveals age-related ultrastructural differences of globular bush cell axons in mouse central auditory system

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2015.05.023openalex-snapshot

In vivo histology of the myelin g-ratio with magnetic resonance imaging

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2015.08.017openalex-snapshot

A revised model for estimating g-ratio from MRI

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2016.02.040openalex-snapshot

Mapping an index of the myelin g-ratio in infants using magnetic resonance imaging

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2016.09.018openalex-snapshot

g-Ratio weighted imaging of the human spinal cord in vivo

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.06.076openalex-snapshot

Evaluating g-ratio weighted changes in the corpus callosum as a function of age and sex

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.08.038openalex-snapshot

Promise and pitfalls of g-ratio estimation with MRI

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.09.018openalex-snapshot

Introducing axonal myelination in connectomics: A preliminary analysis of g-ratio distribution in healthy subjects

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.09.019openalex-snapshot

A comparison of inhomogeneous magnetization transfer, myelin volume fraction, and diffusion tensor imaging measures in healthy children

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.09.053openalex-snapshot

Whole brain g-ratio mapping using myelin water imaging (MWI) and neurite orientation dispersion and density imaging (NODDI)

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.11.029openalex-snapshot

Assessment of microstructural signal compartments across the corpus callosum using multi-echo gradient recalled echo at 7 T

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.11.064openalex-snapshot

Experimental studies of g-ratio MRI in ex vivo mouse brain

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2017.12.038openalex-snapshot

What dominates the time dependence of diffusion transverse to axons: Intra- or extra-axonal water?

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2018.04.009openalex-snapshot

Microstructural imaging in the spinal cord and validation strategies

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2019.03.025openalex-snapshot

Modeling conduction delays in the corpus callosum using MRI-measured g-ratio

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2019.116156openalex-snapshot

Construction of a rat spinal cord atlas of axon morphometry

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2020.116533openalex-snapshot

Diffusion time dependency along the human corpus callosum and exploration of age and sex differences as assessed by oscillating gradient spin-echo diffusion tensor imaging

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2023.119974openalex-snapshot

Temporal trajectories of normal myelination and axonal development assessed by quantitative macromolecular and diffusion MRI: Ultrastructural and immunochemical validation in a rabbit model

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2023.120231openalex-snapshot

Tractography passes the test: Results from the diffusion-simulated connectivity (disco) challenge

inferred← citeshttps://doi.org/10.1016/j.neuroimage.2025.121212openalex-snapshot

Quantifying axonal features of human superficial white matter from three-dimensional multibeam serial electron microscopy data assisted by deep learning

inferred← citeshttps://doi.org/10.1016/j.neuron.2016.07.021openalex-snapshot

Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination

inferred← citeshttps://doi.org/10.1016/j.neuron.2021.02.003openalex-snapshot

Building a (w)rapport between neurons and oligodendroglia: Reciprocal interactions underlying adaptive myelination

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2011.02.052openalex-snapshot

Long-term in vivo regeneration of peripheral nerves through bioengineered nerve grafts

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2014.06.058openalex-snapshot

Unraveling the secrets of white matter – Bridging the gap between cellular, animal and human imaging studies

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2016.07.001openalex-snapshot

Selective hair cell ablation and noise exposure lead to different patterns of changes in the cochlea and the cochlear nucleus

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2018.12.005openalex-snapshot

Effects of Different Doses of Mesenchymal Stem Cells on Functional Recovery After Compressive Spinal-Cord Injury in Mice

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2019.09.023openalex-snapshot

Inosine Accelerates the Regeneration and Anticipates the Functional Recovery after Sciatic Nerve Crush Injury in Mice

inferred← citeshttps://doi.org/10.1016/j.neuroscience.2020.03.026openalex-snapshot

Experimental Demyelination of the Lateral Olfactory Tract and Anterior Commissure

inferred← citeshttps://doi.org/10.1016/j.nicl.2022.103228openalex-snapshot

Longitudinal microstructural MRI markers of demyelination and neurodegeneration in early relapsing-remitting multiple sclerosis: Magnetisation transfer, water diffusion and g-ratio

inferred← citeshttps://doi.org/10.1016/j.nicl.2023.103427openalex-snapshot

Quantitative MRI in leukodystrophies

inferred← citeshttps://doi.org/10.1016/j.oftal.2019.01.013openalex-snapshot

Desarrollo y optimización de un modelo animal para el estudio de las células ganglionares en enfermedad degenerativa de la retina y nervio óptico

inferred← citeshttps://doi.org/10.1016/j.oftale.2019.01.011openalex-snapshot

Development and optimisation of an animal model for the study of ganglion cells in degenerative diseases of the retina and optic nerve

inferred← citeshttps://doi.org/10.1016/j.omtn.2022.04.012openalex-snapshot

Intermittent lipid nanoparticle mRNA administration prevents cortical dysmyelination associated with arginase deficiency

inferred← citeshttps://doi.org/10.1016/j.physbeh.2024.114691openalex-snapshot

Stress-resilient effect of Spirulina platensis on zebrafish chronic unpredictable stress model

inferred← citeshttps://doi.org/10.1016/j.pneurobio.2024.102568openalex-snapshot

Tdrd3-null mice show post-transcriptional and behavioral impairments associated with neurogenesis and synaptic plasticity

inferred← citeshttps://doi.org/10.1016/j.pscychresns.2020.111046openalex-snapshot

Neural correlates of symptom severity in obsessive-compulsive disorder using magnetization transfer and diffusion tensor imaging

inferred← citeshttps://doi.org/10.1016/j.tice.2014.09.002openalex-snapshot

Role of calorie restriction in alleviation of age-related morphological and biochemical changes in sciatic nerve

inferred← citeshttps://doi.org/10.1016/j.tice.2019.08.004openalex-snapshot

Nicotine-induced oxidative stress alters sciatic nerve barriers in rat through modulation of ZO-1 & VEGF expression

inferred← citeshttps://doi.org/10.1016/j.tox.2018.06.004openalex-snapshot

Repeated exposures to diisopropylfluorophosphate result in structural disruptions of myelinated axons and persistent impairments of axonal transport in the brains of rats

inferred← citeshttps://doi.org/10.1016/j.toxrep.2025.101974openalex-snapshot

Betaine alleviates deficits in motor behavior, neurotoxic effects, and neuroinflammatory responses in a rat model of demyelination

inferred← citeshttps://doi.org/10.1016/j.ymeth.2015.09.008openalex-snapshot

Evaluation of biodegradable polymer conduits – poly(l-lactic acid) – for guiding sciatic nerve regeneration in mice

inferred← citeshttps://doi.org/10.1021/acsami.0c08457openalex-snapshot

CNT/Sericin Conductive Nerve Guidance Conduit Promotes Functional Recovery of Transected Peripheral Nerve Injury in a Rat Model

inferred← citeshttps://doi.org/10.1021/acsami.4c15013openalex-snapshot

Wnt 3a-Modified Scaffolds Improve Nerve Regeneration by Boosting Schwann Cell Function

inferred← citeshttps://doi.org/10.1021/acsnano.5c16373openalex-snapshot

Meningeal Lymphatic System-Driven Nanodelivery Unlocks Ursolic Acid’s Pleiotropic Benefits To Optimize Multiple Sclerosis Treatment

inferred← citeshttps://doi.org/10.1038/jcbfm.2014.154openalex-snapshot

Bilirubin and its Oxidation Products Damage Brain White Matter

inferred← citeshttps://doi.org/10.1038/mt.2013.138openalex-snapshot

A Single Intravenous rAAV Injection as Late as P20 Achieves Efficacious and Sustained CNS Gene Therapy in Canavan Mice

inferred← citeshttps://doi.org/10.1038/nn.4200openalex-snapshot

Remodeling myelination: implications for mechanisms of neural plasticity

inferred← citeshttps://doi.org/10.1038/s41380-021-01318-4openalex-snapshot

Tbx1, a gene encoded in 22q11.2 copy number variant, is a link between alterations in fimbria myelination and cognitive speed in mice

inferred← citeshttps://doi.org/10.1038/s41380-026-03460-3openalex-snapshot

Aerobic glycolysis in Schizophrenia: Developmental rescue or energetic breakdown?

inferred← citeshttps://doi.org/10.1038/s41392-025-02398-2openalex-snapshot

Astrocytic monoamine oxidase B (MAOB)–gamma-aminobutyric acid (GABA) axis as a molecular brake on repair following spinal cord injury

showing the first 200 of 439

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