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Integrated Expression Profiling and Genome-Wide Analysis of ChREBP Targets Reveals the Dual Role for ChREBP in Glucose-Regulated Gene Expression

https://doi.org/10.1371/journal.pone.0022544
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/0471250953.bi0204s00openalex-snapshot
Discovering Novel Sequence Motifs with MEME
inferredcites →https://doi.org/10.1016/j.bbrc.2008.06.101openalex-snapshot
Regulation of lipogenesis via BHLHB2/DEC1 and ChREBP feedback looping
inferredcites →https://doi.org/10.1016/s0076-6879(04)89001-3openalex-snapshot
Quantitative Real-Time Polymerase Chain Reaction Measurement of Regulators of G-Protein Signaling mRNA Levels in Mouse Tissues
inferredcites →https://doi.org/10.1038/emboj.2009.88openalex-snapshot
ChIP‐Seq of ERα and RNA polymerase II defines genes differentially responding to ligands
inferredcites →https://doi.org/10.1038/nbt.1505openalex-snapshot
An integrated software system for analyzing ChIP-chip and ChIP-seq data
inferredcites →https://doi.org/10.1038/nmeth0807-613openalex-snapshot
ChIP-seq: welcome to the new frontier
inferredcites →https://doi.org/10.1038/nmeth1068openalex-snapshot
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing
inferredcites →https://doi.org/10.1053/j.gastro.2008.02.076openalex-snapshot
Sp1 Is Required for Glucose-Induced Transcriptional Regulation of Mouse Vesicular Glutamate Transporter 2 Gene
inferredcites →https://doi.org/10.1053/jhep.2001.22176openalex-snapshot
Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting
inferredcites →https://doi.org/10.1073/pnas.0401516101openalex-snapshot
Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis
inferredcites →https://doi.org/10.1073/pnas.0405238101openalex-snapshot
Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
inferredcites →https://doi.org/10.1073/pnas.0604129103openalex-snapshot
Global mapping of c-Myc binding sites and target gene networks in human B cells
inferredcites →https://doi.org/10.1073/pnas.0911316106openalex-snapshot
The glucose-responsive transcription factor ChREBP contributes to glucose-dependent anabolic synthesis and cell proliferation
inferredcites →https://doi.org/10.1073/pnas.161284298openalex-snapshot
A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver
inferredcites →https://doi.org/10.1073/pnas.231370798openalex-snapshot
Glucose and cAMP regulate the L-type pyruvate kinase gene by phosphorylation/dephosphorylation of the carbohydrate response element binding protein
inferredcites →https://doi.org/10.1074/jbc.270.37.21991openalex-snapshot
Two CACGTG Motifs with Proper Spacing Dictate the Carbohydrate Regulation of Hepatic Gene Transcription
inferredcites →https://doi.org/10.1074/jbc.271.25.14692openalex-snapshot
Dephosphorylation of Sp1 by Protein Phosphatase 1 Is Involved in the Glucose-mediated Activation of the Acetyl-CoA Carboxylase Gene
inferredcites →https://doi.org/10.1074/jbc.271.3.1385openalex-snapshot
Sp1 Mediates Glucose Activation of the Acetyl-CoA Carboxylase Promoter
inferredcites →https://doi.org/10.1074/jbc.273.14.8225openalex-snapshot
Sp1 Sites Mediate Activation of the Plasminogen Activator Inhibitor-1 Promoter by Glucose in Vascular Smooth Muscle Cells
inferredcites →https://doi.org/10.1074/jbc.m010192200openalex-snapshot
Improved Statistical Inference from DNA Microarray Data Using Analysis of Variance and A Bayesian Statistical Framework
inferredcites →https://doi.org/10.1074/jbc.m311301200openalex-snapshot
Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes
inferredcites →https://doi.org/10.1074/jbc.m312475200openalex-snapshot
Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression
inferredcites →https://doi.org/10.1074/jbc.m413063200openalex-snapshot
Direct Role of ChREBP·Mlx in Regulating Hepatic Glucose-responsive Genes
inferredcites →https://doi.org/10.1074/jbc.m601576200openalex-snapshot
ChREBP•Mlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver
inferredcites →https://doi.org/10.1074/jbc.m605023200openalex-snapshot
The Liver X Receptor (LXR) and Hepatic Lipogenesis
inferredcites →https://doi.org/10.1074/jbc.r000017200openalex-snapshot
Sterol Regulatory Element-binding Proteins (SREBPs): Key Regulators of Nutritional Homeostasis and Insulin Action
inferredcites →https://doi.org/10.1093/bioinformatics/btp570openalex-snapshot
W-ChIPMotifs: a web application tool forde novomotif discovery from ChIP-based high-throughput data
inferredcites →https://doi.org/10.1093/hmg/10.6.617openalex-snapshot
WBSCR14, a gene mapping to the Williams-Beuren syndrome deleted region, is a new member of the Mlx transcription factor network
inferredcites →https://doi.org/10.1093/nar/gkl987openalex-snapshot
A critical role for the loop region of the basic helix-loop-helix/leucine zipper protein Mlx in DNA binding and glucose-regulated transcription
inferredcites →https://doi.org/10.1093/nar/gkn382openalex-snapshot
Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing
inferredcites →https://doi.org/10.1093/nar/gkn488openalex-snapshot
Genome-wide identification ofin vivoprotein-DNA binding sites from ChIP-Seq data
inferredcites →https://doi.org/10.1093/nar/gkp939openalex-snapshot
The UCSC Genome Browser database: update 2010
inferredcites →https://doi.org/10.1093/nar/gkq963openalex-snapshot
The UCSC Genome Browser database: update 2011
inferredcites →https://doi.org/10.1101/gad.501108openalex-snapshot
Genome-wide profiling of PPARγ:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
inferredcites →https://doi.org/10.1101/gr.078212.108openalex-snapshot
Mapping short DNA sequencing reads and calling variants using mapping quality scores
inferredcites →https://doi.org/10.1126/science.1141319openalex-snapshot
Genome-Wide Mapping of in Vivo Protein-DNA Interactions
inferredcites →https://doi.org/10.1128/mcb.00657-05openalex-snapshot
MondoA-Mlx Heterodimers Are Candidate Sensors of Cellular Energy Status: Mitochondrial Localization and Direct Regulation of Glycolysis
inferredcites →https://doi.org/10.1146/annurev.nutr.17.1.405openalex-snapshot
REGULATION OF THE EXPRESSION OF LIPOGENIC ENZYME GENES BY CARBOHYDRATE
inferredcites →https://doi.org/10.1152/ajpendo.00027.2006openalex-snapshot
Deficiency of carbohydrate-activated transcription factor ChREBP prevents obesity and improves plasma glucose control in leptin-deficient ( ob/ob ) mice
inferredcites →https://doi.org/10.1186/gb-2007-8-9-r183openalex-snapshot
The DAVID Gene Functional Classification Tool: a novel biological module-centric algorithm to functionally analyze large gene lists
inferredcites →https://doi.org/10.1186/gb-2009-10-3-r25openalex-snapshot
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome
inferredcites →https://doi.org/10.1210/en.2004-1378openalex-snapshot
Thioredoxin-Interacting Protein Is Stimulated by Glucose through a Carbohydrate Response Element and Induces β-Cell Apoptosis
inferredcites →https://doi.org/10.1210/en.2008-0215openalex-snapshot
Hepatic Expression of the SPOT 14 (S14) Paralog S14-Related (Mid1 Interacting Protein) Is Regulated by Dietary Carbohydrate
inferredcites →https://doi.org/10.1371/journal.pone.0008397openalex-snapshot
Tandem ChoRE and CCAAT Motifs and Associated Factors Regulate Txnip Expression in Response to Glucose or Adenosine-Containing Molecules
inferredcites →https://doi.org/10.2202/1544-6115.1027openalex-snapshot
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments
inferredcites →https://doi.org/10.2337/db06-0200openalex-snapshot
Liver-Specific Inhibition of ChREBP Improves Hepatic Steatosis and Insulin Resistance in ob/ob Mice
inferredcites →https://doi.org/10.2337/db08-0868openalex-snapshot
Carbohydrate-Responsive Element-Binding Protein (ChREBP) Is a Negative Regulator of ARNT/HIF-1β Gene Expression in Pancreatic Islet β-Cells
inferredcites →https://doi.org/10.2337/diabetes.54.6.1684openalex-snapshot
Glucose-Stimulated Upregulation of GLUT2 Gene Is Mediated by Sterol Response Element–Binding Protein-1c in the Hepatocytes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Body‐Wide Inactivation of the Myc‐Like Mlx Transcription Factor Network Accelerates Aging and Increases the Lifetime Cancer Incidence
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Metabolic crosstalk between the heart and liver impacts familial hypertrophic cardiomyopathy
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ChREBP and cancer
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Lipids, Low-Grade Chronic Inflammation and NAFLD
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Endoplasmic reticulum-mitochondria calcium signaling in hepatic metabolic diseases
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Rat glucagon receptor mRNA is directly regulated by glucose through transactivation of the carbohydrate response element binding protein
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The role of glycerol-3-phosphate dehydrogenase 1 in the progression of fatty liver after acute ethanol administration in mice
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Hepatic Elovl6 gene expression is regulated by the synergistic action of ChREBP and SREBP-1c
inferred← citeshttps://doi.org/10.1016/j.biocel.2013.09.004openalex-snapshot
Flightless I homolog negatively regulates ChREBP activity in cancer cells
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Sugar sensing by ChREBP/Mondo-Mlx — new insight into downstream regulatory networks and integration of nutrient-derived signals
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Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe
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Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells
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Glucose metabolism and regulation in establishing human stem cell-derived β cell maturation
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Sweet Sixteenth for ChREBP: Established Roles and Future Goals
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.10.008openalex-snapshot
Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis
inferred← citeshttps://doi.org/10.1016/j.cmet.2018.04.015openalex-snapshot
The BCKDH Kinase and Phosphatase Integrate BCAA and Lipid Metabolism via Regulation of ATP-Citrate Lyase
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Network-based identification and prioritization of key transcriptional factors of diabetic kidney disease
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Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
inferred← citeshttps://doi.org/10.1016/j.gene.2015.03.057openalex-snapshot
ChREBP and LXRα mediate synergistically lipogenesis induced by glucose in porcine adipocytes
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Bioactive small compounds effectively inhibit ChREBP overexpression to treat NAFLD and T2DM: A computational drug development approach
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Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption
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Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia
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A krill powder-diet reduces fatty acid and amino acid catabolism while increasing mitochondrial oxidative phosphorylation, a study of the hepatic transcriptome in mice
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LYPLAL1 rare loss-of-function variants in humans and deletion in human hepatoma cells protect against MASLD
inferred← citeshttps://doi.org/10.1016/j.jmb.2025.169189openalex-snapshot
An acetylated Lysine Residue of Its Low-glucose Inhibitory Domain Controls Activity and Protein Interactions of ChREBP
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.121042openalex-snapshot
Reactive oxygen species induce HNF-4α expression via the ASK1-CREB pathway, promoting ChREBP expression and lipogenesis in hepatocytes
inferred← citeshttps://doi.org/10.1016/j.metabol.2017.01.033openalex-snapshot
MondoA/ChREBP: The usual suspects of transcriptional glucose sensing; Implication in pathophysiology
inferred← citeshttps://doi.org/10.1016/j.metabol.2018.04.006openalex-snapshot
ChREBP deficiency leads to diarrhea-predominant irritable bowel syndrome
inferred← citeshttps://doi.org/10.1016/j.molmet.2017.07.006openalex-snapshot
Deletion of hepatic carbohydrate response element binding protein (ChREBP) impairs glucose homeostasis and hepatic insulin sensitivity in mice
inferred← citeshttps://doi.org/10.1016/j.molmet.2022.101548openalex-snapshot
The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation
inferred← citeshttps://doi.org/10.1016/j.molmet.2022.101646openalex-snapshot
T3 and glucose increase expression of phosphoenolpyruvate carboxykinase (PCK1) leading to increased β-cell proliferation
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101722openalex-snapshot
The GCKR-P446L gene variant predisposes to raised blood cholesterol and lower blood glucose in the P446L mouse-a model for GCKR rs1260326
inferred← citeshttps://doi.org/10.1016/j.molmet.2023.101848openalex-snapshot
Transcriptional activation of the Myc gene by glucose in β-cells requires a ChREBP-dependent 3-D chromatin interaction between the Myc and Pvt1 genes
inferred← citeshttps://doi.org/10.1016/j.semcdb.2012.02.007openalex-snapshot
Glucose sensing by ChREBP/MondoA–Mlx transcription factors
inferred← citeshttps://doi.org/10.1016/j.tem.2013.01.003openalex-snapshot
Novel insights into ChREBP regulation and function
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Hexokinase-2 Glycolytic Overload in Diabetes and Ischemia–Reperfusion Injury
inferred← citeshttps://doi.org/10.1016/j.ygeno.2014.02.002openalex-snapshot
H3K4me2 reliably defines transcription factor binding regions in different cells
inferred← citeshttps://doi.org/10.1016/j.ygeno.2017.06.006openalex-snapshot
Visualizing the regulatory role of Angiopoietin-like protein 8 (ANGPTL8) in glucose and lipid metabolic pathways
inferred← citeshttps://doi.org/10.1016/j.ymgme.2014.04.007openalex-snapshot
Pleiotropic genes for metabolic syndrome and inflammation
inferred← citeshttps://doi.org/10.1038/bjc.2013.765openalex-snapshot
Role of carbohydrate response element-binding protein (ChREBP) in generating an aerobic metabolic phenotype and in breast cancer progression
inferred← citeshttps://doi.org/10.1038/ng.2500openalex-snapshot
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations
inferred← citeshttps://doi.org/10.1038/s41388-023-02831-2openalex-snapshot
Glucose-induced and ChREBP: MLX-mediated lipogenic program promotes hepatocellular carcinoma development
inferred← citeshttps://doi.org/10.1038/s41420-022-01079-1openalex-snapshot
CHREBP suppresses gastric cancer progression via the cyclin D1-Rb-E2F1 pathway
inferred← citeshttps://doi.org/10.1038/s41467-017-02756-xopenalex-snapshot
Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts
inferred← citeshttps://doi.org/10.1038/s41574-023-00809-4openalex-snapshot
The role of ChREBP in carbohydrate sensing and NAFLD development
inferred← citeshttps://doi.org/10.1038/srep05013openalex-snapshot
Elevated circulating lipasin/betatrophin in human type 2 diabetes and obesity
inferred← citeshttps://doi.org/10.1038/srep23944openalex-snapshot
Identification of HNF-4α as a key transcription factor to promote ChREBP expression in response to glucose
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Deciphering the expression dynamics of ANGPTL8 associated regulatory network in insulin resistance using formal modelling approaches
inferred← citeshttps://doi.org/10.1074/jbc.m112.418855openalex-snapshot
Structural Characterization of a Unique Interface between Carbohydrate Response Element-binding Protein (ChREBP) and 14-3-3β Protein
inferred← citeshttps://doi.org/10.1074/jbc.m113.530139openalex-snapshot
High Glucose-induced O-GlcNAcylated Carbohydrate Response Element-binding Protein (ChREBP) Mediates Mesangial Cell Lipogenesis and Fibrosis
inferred← citeshttps://doi.org/10.1074/jbc.ra118.004099openalex-snapshot
Myc and ChREBP transcription factors cooperatively regulate normal and neoplastic hepatocyte proliferation in mice
inferred← citeshttps://doi.org/10.1074/jbc.ra120.013228openalex-snapshot
Role for carbohydrate response element-binding protein (ChREBP) in high glucose-mediated repression of long noncoding RNA Tug1
inferred← citeshttps://doi.org/10.1074/mcp.m116.061416openalex-snapshot
Validation, Identification, and Biological Consequences of the Site-specific O-GlcNAcylation Dynamics of Carbohydrate-responsive Element-binding Protein (ChREBP)
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Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1080/19490976.2020.1854639openalex-snapshot
Personalized B cell response to the Lactobacillus rhamnosus GG probiotic in healthy human subjects: a randomized trial
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Hepatic DGAT2 gene expression is regulated by the synergistic action of ChREBP and SP1 in HepG2 cells
inferred← citeshttps://doi.org/10.1080/23723556.2015.1026528openalex-snapshot
A novel role for the extended MYC network in cancer cell survival
inferred← citeshttps://doi.org/10.1097/cm9.0000000000001545openalex-snapshot
Fructose and metabolic diseases: too much to be good
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Association of the ESR1 polymorphism with menopause and MLXIPL genetic variant influence serum uric acid levels in Slovak midlife women
inferred← citeshttps://doi.org/10.1097/md.0000000000007456openalex-snapshot
Advanced glycation end products promote ChREBP expression and cell proliferation in liver cancer cells by increasing reactive oxygen species
inferred← citeshttps://doi.org/10.1101/2021.05.18.444615openalex-snapshot
Loss of intestinal ChREBP impairs absorption of dietary sugars and prevents glycemic excursion curves
inferred← citeshttps://doi.org/10.1101/2023.02.04.527056openalex-snapshot
Role of acetoacetyl-CoA synthetase in glucose uptake by HepG2 cells
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The Myc-Like Mlx Network Impacts Aging and Metabolism
inferred← citeshttps://doi.org/10.1111/jbg.12841openalex-snapshot
A review of the role of transcription factors in regulating adipogenesis and lipogenesis in beef cattle
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The regulation and role of carbohydrate response element‐binding protein in metabolic homeostasis and disease
inferred← citeshttps://doi.org/10.1111/obr.70096openalex-snapshot
Fueling Disease: ACSS2 in Obesity‐Associated Metabolic Disorders and Cancer Progression
inferred← citeshttps://doi.org/10.1128/mcb.01004-12openalex-snapshot
Farnesoid X Receptor Inhibits the Transcriptional Activity of Carbohydrate Response Element Binding Protein in Human Hepatocytes
inferred← citeshttps://doi.org/10.1128/mcb.01576-12openalex-snapshot
Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter
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Comparison of the adipogenesis in intramuscular and subcutaneous adipocytes from Bamei and Landrace pigs
inferred← citeshttps://doi.org/10.1152/ajpendo.00326.2020openalex-snapshot
ChREBP downregulates SNAT2 amino acid transporter expression through interactions with SMRT in response to a high-carbohydrate diet
inferred← citeshttps://doi.org/10.1152/ajpgi.00328.2012openalex-snapshot
Nordihydroguaiaretic acid improves metabolic dysregulation and aberrant hepatic lipid metabolism in mice by both PPARα-dependent and -independent pathways
inferred← citeshttps://doi.org/10.1152/physiol.00016.2015openalex-snapshot
Integration of ChREBP-Mediated Glucose Sensing into Whole Body Metabolism
inferred← citeshttps://doi.org/10.1155/2015/821761openalex-snapshot
Gene Network Analysis of Glucose Linked Signaling Pathways and Their Role in Human Hepatocellular Carcinoma Cell Growth and Survival in HuH7 and HepG2 Cell Lines
inferred← citeshttps://doi.org/10.1155/jnme/5571686openalex-snapshot
Mindful Eating: A Deep Insight Into Fructose Metabolism and Its Effects on Appetite Regulation and Brain Function
inferred← citeshttps://doi.org/10.1158/0008-5472.can-25-0235openalex-snapshot
ChREBP-Mediated Choline Deprivation and Chemokine Secretion Shape Tumor-Associated Macrophages to Promote Immune Evasion
inferred← citeshttps://doi.org/10.1172/jci.insight.129119openalex-snapshot
MondoA drives muscle lipid accumulation and insulin resistance
inferred← citeshttps://doi.org/10.1172/jci.insight.153740openalex-snapshot
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis
inferred← citeshttps://doi.org/10.1172/jci41636openalex-snapshot
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans
inferred← citeshttps://doi.org/10.1186/s12986-016-0121-yopenalex-snapshot
Microarray analysis of gene expression in liver, adipose tissue and skeletal muscle in response to chronic dietary administration of NDGA to high-fructose fed dyslipidemic rats
inferred← citeshttps://doi.org/10.1194/jlr.m049130openalex-snapshot
Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity
inferred← citeshttps://doi.org/10.1194/jlr.m081836openalex-snapshot
Interplay between ChREBP and SREBP-1c coordinates postprandial glycolysis and lipogenesis in livers of mice
inferred← citeshttps://doi.org/10.1210/en.2014-1666openalex-snapshot
Genome-Wide Analysis of ChREBP Binding Sites on Male Mouse Liver and White Adipose Chromatin
inferred← citeshttps://doi.org/10.1210/en.2015-1209openalex-snapshot
The Glucose Sensor ChREBP Links De Novo Lipogenesis to PPARγ Activity and Adipocyte Differentiation
inferred← citeshttps://doi.org/10.1242/jeb.240432openalex-snapshot
Loss of Stearoyl-CoA desaturase 1 leads to cardiac dysfunction and lipotoxicity
inferred← citeshttps://doi.org/10.1371/journal.pgen.1002959openalex-snapshot
Determinants of Human Adipose Tissue Gene Expression: Impact of Diet, Sex, Metabolic Status, and Cis Genetic Regulation
inferred← citeshttps://doi.org/10.1371/journal.pgen.1003438openalex-snapshot
Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila
inferred← citeshttps://doi.org/10.1371/journal.pone.0102730openalex-snapshot
Multiple E-Boxes in the Distal Promoter of the Rat Pyruvate Carboxylase Gene Function as a Glucose-Responsive Element
inferred← citeshttps://doi.org/10.1371/journal.pone.0147411openalex-snapshot
ChREBP Regulates Itself and Metabolic Genes Implicated in Lipid Accumulation in β–Cell Line
inferred← citeshttps://doi.org/10.1371/journal.pone.0168797openalex-snapshot
Dietary Macronutrient Composition Directs ChREBP Isoform Expression and Glucose Metabolism in Mice
inferred← citeshttps://doi.org/10.14740/jem405wopenalex-snapshot
Circulating Betatrophin and Hepatocyte Growth Factor in Type 2 Diabetic Patients: Their Relationship With Disease Prognosis
inferred← citeshttps://doi.org/10.14814/phy2.12730openalex-snapshot
High glucose induces platelet-derived growth factor-C via carbohydrate response element-binding protein in glomerular mesangial cells
inferred← citeshttps://doi.org/10.1507/endocrj.ej13-0121openalex-snapshot
Recent progress on the role of ChREBP in glucose and lipid metabolism [Review]
inferred← citeshttps://doi.org/10.1507/endocrj.ej22-0083openalex-snapshot
The physiological and pathophysiological roles of carbohydrate response element binding protein in the kidney
inferred← citeshttps://doi.org/10.15252/embj.201591385openalex-snapshot
The transcription factor Cabut coordinates energy metabolism and the circadian clock in response to sugar sensing
inferred← citeshttps://doi.org/10.1530/erc-17-0562openalex-snapshot
Interaction of BRAF-induced ETS factors with mutant TERT promoter in papillary thyroid cancer
inferred← citeshttps://doi.org/10.1530/joe-11-0480openalex-snapshot
Roles of Ca2+ ions in the control of ChREBP nuclear translocation
inferred← citeshttps://doi.org/10.1534/genetics.117.199885openalex-snapshot
Regulation of Carbohydrate Energy Metabolism in Drosophila melanogaster.
inferred← citeshttps://doi.org/10.1590/1806-9061-2017-0482openalex-snapshot
Molecular Cloning and Mrna Expression Analysis of Sichuan White Goose (Anser Cygnoides) Chrebp Gene
inferred← citeshttps://doi.org/10.17582/journal.pjz/2019.51.3.855.863openalex-snapshot
Association of ChREBP Expression and Polymorphism with Serum Biochemical Indices in Cherry Valley Duck
inferred← citeshttps://doi.org/10.18632/oncotarget.9520openalex-snapshot
ChREBP promotes the differentiation of leukemia-initiating cells to inhibit leukemogenesis through the TXNIP/RUNX1 pathways
inferred← citeshttps://doi.org/10.2174/1389450123666220303092324openalex-snapshot
Overview on Thioredoxin-Interacting Protein (TXNIP): A Potential Target for Diabetes Intervention
inferred← citeshttps://doi.org/10.2174/1871530322666211220110810openalex-snapshot
Hepatic Lipid Metabolism Disorder and Atherosclerosis
inferred← citeshttps://doi.org/10.2337/db15-0239openalex-snapshot
Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation
inferred← citeshttps://doi.org/10.32439/ps.v7i1.1-8openalex-snapshot
Plant Bioacoustics: A system of plant-sound relationship
inferred← citeshttps://doi.org/10.3389/fendo.2014.00230openalex-snapshot
O-GlcNAcylation Links ChREBP and FXR to Glucose-Sensing
inferred← citeshttps://doi.org/10.3389/fendo.2020.587189openalex-snapshot
ChREBP-Mediated Regulation of Lipid Metabolism: Involvement of the Gut Microbiota, Liver, and Adipose Tissue
inferred← citeshttps://doi.org/10.3389/fendo.2023.1095440openalex-snapshot
New insights into the inter-organ crosstalk mediated by ChREBP
inferred← citeshttps://doi.org/10.3389/fendo.2023.1268308openalex-snapshot
Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complications
inferred← citeshttps://doi.org/10.3389/fphar.2025.1669805openalex-snapshot
Dysregulated bile acid metabolism drives lipid peroxidation and ferroptosis in NAFLD: therapeutic potential for traditional Chinese medicine
inferred← citeshttps://doi.org/10.3389/fphys.2021.702826openalex-snapshot
Branched-chain Amino Acids: Catabolism in Skeletal Muscle and Implications for Muscle and Whole-body Metabolism
inferred← citeshttps://doi.org/10.3390/biom11121886openalex-snapshot
Insulin-Responsive Transcription Factors
inferred← citeshttps://doi.org/10.3390/books978-3-03897-054-5openalex-snapshot
Dietary Fructose and Glucose: The Multifacetted Aspects of Their Metabolism and Implication for Human Health
inferred← citeshttps://doi.org/10.3390/books978-3-03897-599-1openalex-snapshot
Nutritional Intake and the Risk for Non-alcoholic Fatty Liver Disease (NAFLD)
inferred← citeshttps://doi.org/10.3390/cells11040747openalex-snapshot
Normal and Neoplastic Growth Suppression by the Extended Myc Network
inferred← citeshttps://doi.org/10.3390/cells8101225openalex-snapshot
Transcriptional Regulation of Energy Metabolism in Cancer Cells
inferred← citeshttps://doi.org/10.3390/ijms20020298openalex-snapshot
Homeostasis of Glucose and Lipid in Non-Alcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.3390/ijms22010331openalex-snapshot
Deletion of KLF10 Leads to Stress-Induced Liver Fibrosis upon High Sucrose Feeding
inferred← citeshttps://doi.org/10.3390/ijms23042165openalex-snapshot
Hexokinase-2-Linked Glycolytic Overload and Unscheduled Glycolysis—Driver of Insulin Resistance and Development of Vascular Complications of Diabetes
inferred← citeshttps://doi.org/10.3390/ijms25021276openalex-snapshot
New Insights into the Role of KLF10 in Tissue Fibrosis
inferred← citeshttps://doi.org/10.3390/ijms25063427openalex-snapshot
Domestication Gene Mlx and Its Partner Mondo Are Involved in Controlling the Larval Body Size and Cocoon Shell Weight of Bombyx mori
inferred← citeshttps://doi.org/10.3390/nu10030321openalex-snapshot
ChREBP Rather Than SHP Regulates Hepatic VLDL Secretion
inferred← citeshttps://doi.org/10.3390/nu9020181openalex-snapshot
The Role of Carbohydrate Response Element Binding Protein in Intestinal and Hepatic Fructose Metabolism
inferred← citeshttps://doi.org/10.3724/abbs.2023158openalex-snapshot
GLUT5: structure, functions, diseases and potential applications
inferred← citeshttps://doi.org/10.3748/wjg.v18.i46.6790openalex-snapshot
Have guidelines addressing physical activity been established in nonalcoholic fatty liver disease?
inferred← citeshttps://doi.org/10.37496/rbz5220220029openalex-snapshot
Txnip inhibits porcine adipocyte differentiation through PPARγ and impairs the induction of glucose via ChREBP
inferred← citeshttps://doi.org/10.3892/ijmm.2018.3702openalex-snapshot
Histone modifications in fatty acid synthase modulated by carbohydrate responsive element binding protein are associated with non‑alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.4068/cmj.2015.51.3.115openalex-snapshot
Circulating Betatrophin Levels Are Associated with the Lipid Profile in Type 2 Diabetes
inferred← citeshttps://doi.org/10.4137/grsb.s11782openalex-snapshot
Central Role of the PPARγ Gene Network in Coordinating Beef Cattle Intramuscular Adipogenesis in Response to Weaning Age and Nutrition
inferred← citeshttps://doi.org/10.48780/publications.aston.ac.uk.00041187openalex-snapshot
The role of odd chain fatty acids on hepatocyte and monocyte function
inferred← citeshttps://doi.org/10.5483/bmbrep.2017.50.9.124openalex-snapshot
Bach2 represses the AP-1-driven induction of interleukin-2 gene transcription in CD4+ T cells
inferred← citeshttps://doi.org/10.5483/bmbrep.2018.51.9.197openalex-snapshot
Recent insights into the role of ChREBP in intestinal fructose absorption and metabolism
inferred← citeshttps://doi.org/10.70675/0aca726cz3a4bz4a79z8398z0300a98caba3openalex-snapshot
Uncovering ubiquitylation pathways in liver metabolism by a proteomic approach
inferred← citeshttps://doi.org/10.70675/406936f5zb422z453ez84d1z38c3f35b82e9openalex-snapshot
Etude de la zonation des voies métaboliques du glucose en fonction du statut nutritionnel : implication du récepteur nucléaire Farnesoid X Receptor (FXR)
inferred← citeshttps://doi.org/10.70675/5d147ab4zad37z4f6bzac51z32a08efeaa51openalex-snapshot
Inter-organ communication in physiology and pathophysiology : a role for the ChREBP-FGF21 axis?
inferred← citeshttps://doi.org/10.7554/elife.28527openalex-snapshot
Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity
inferred← citeshttps://doi.org/10.7554/elife.57068openalex-snapshot
MondoA regulates gene expression in cholesterol biosynthesis-associated pathways required for zebrafish epiboly
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