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Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of South African Infants throughout the First Year of Life

https://doi.org/10.1371/journal.pone.0044763

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Correlation analysis of intracellular and secreted cytokines via the generalized integrated mean fluorescence intensity

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TLR‐mediated stimulation of APC: Distinct cytokine responses of B cells and dendritic cells

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Simultaneous Statistical Inference

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Current Concepts of Infections of the Fetus and Newborn Infant

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Developmental Immunology and Role of Host Defenses in Fetal and Neonatal Susceptibility to Infection

inferredcites →https://doi.org/10.1016/b978-1-4160-6400-8.00001-8openalex-snapshot

Current Concepts of Infections of the Fetus and Newborn Infant

inferredcites →https://doi.org/10.1016/j.clim.2006.02.003openalex-snapshot

Towards subtlety: Understanding the role of Toll-like receptor signaling in susceptibility to human infections

inferredcites →https://doi.org/10.1016/j.clim.2007.03.345openalex-snapshot

Standardization and Quality Assurance of Cytokine Flow Cytometry Assays

inferredcites →https://doi.org/10.1016/j.clim.2009.07.003openalex-snapshot

Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life

inferredcites →https://doi.org/10.1016/j.clim.2010.12.011openalex-snapshot

Immune system development during early childhood in tropical Latin America: Evidence for the age-dependent down regulation of the innate immune response

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The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

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Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

inferredcites →https://doi.org/10.1016/j.jaci.2010.09.020openalex-snapshot

Differences in innate immune function between allergic and nonallergic children: New insights into immune ontogeny

inferredcites →https://doi.org/10.1016/j.jim.2008.04.013openalex-snapshot

Polychromatic flow cytometric high-throughput assay to analyze the innate immune response to Toll-like receptor stimulation

inferredcites →https://doi.org/10.1016/j.jim.2011.01.009openalex-snapshot

Variables to be controlled in the assessment of blood innate immune responses to Toll-like receptor stimulation

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Optimization of a whole blood intracellular cytokine assay for measuring innate cell responses to mycobacteria

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The unmet need in the elderly: How immunosenescence, CMV infection, co-morbidities and frailty are a challenge for the development of more effective influenza vaccines

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Uninfected but not unaffected: chronic maternal infections during pregnancy, fetal immunity, and susceptibility to postnatal infections

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Programming the magnitude and persistence of antibody responses with innate immunity

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Immunological mechanisms of vaccination

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Quality assurance for polychromatic flow cytometry

inferredcites →https://doi.org/10.1038/nprot.2006.268openalex-snapshot

Intracellular cytokine optimization and standard operating procedure

inferredcites →https://doi.org/10.1038/nri1394openalex-snapshot

Neonatal adaptive immunity comes of age

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Infectious Diseases of the Fetus and Newborn Infant

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T cell-mediated immune responses in human newborns: ready to learn?

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Induction of Antigen-Specific Immunity in Human Neonates and Infants

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Standardization of cytokine flow cytometry assays

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Comparison of Immunological Status of African and European Cord Blood Mononuclear Cells

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Developmental Biology of the Innate Immune Response: Implications for Neonatal and Infant Vaccine Development

inferredcites →https://doi.org/10.1289/ehp.0800366openalex-snapshot

Spontaneous Cytokine Production in Children According to Biological Characteristics and Environmental Exposures

inferredcites →https://doi.org/10.1371/journal.pone.0010407openalex-snapshot

Acquisition of Adult-Like TLR4 and TLR9 Responses during the First Year of Life

inferredcites →https://doi.org/10.1371/journal.pone.0015041openalex-snapshot

Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of Human Blood Mononuclear Cells

inferredcites →https://doi.org/10.1371/journal.pone.0018185openalex-snapshot

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

inferredcites →https://doi.org/10.1371/journal.pone.0018319openalex-snapshot

Interethnic Differences in Antigen-Presenting Cell Activation and TLR Responses in Malian Children during Plasmodium falciparum Malaria

inferredcites →https://doi.org/10.1371/journal.pone.0036793openalex-snapshot

Ontogeny of Toll-Like and NOD-Like Receptor-Mediated Innate Immune Responses in Papua New Guinean Infants

inferredcites →https://doi.org/10.1371/journal.ppat.1002174openalex-snapshot

Association of Human TLR1 and TLR6 Deficiency with Altered Immune Responses to BCG Vaccination in South African Infants

inferredcites →https://doi.org/10.1586/erv.10.41openalex-snapshot

The challenge of assessing infant vaccine responses in resource-poor settings

inferredcites →https://doi.org/10.4049/jimmunol.0901481openalex-snapshot

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

inferredcites →https://doi.org/10.4049/jimmunol.173.7.4627openalex-snapshot

Selective Impairment of TLR-Mediated Innate Immunity in Human Newborns: Neonatal Blood Plasma Reduces Monocyte TNF-α Induction by Bacterial Lipopeptides, Lipopolysaccharide, and Imiquimod, but Preserves the Response to R-848

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Newborn BCG Vaccination Induces Robust Infant IFN

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Developmental immunology and role of host defenses in fetal and neonatal susceptibility to infection

inferred← citeshttps://doi.org/10.1016/j.cyto.2016.04.001openalex-snapshot

In vitro cytokine induction by TLR-activating vaccine adjuvants in human blood varies by age and adjuvant

inferred← citeshttps://doi.org/10.1016/j.forsciint.2014.09.022openalex-snapshot

Review of immunological and virological aspects as contributory factors in Sudden Unexpected Death in Infancy (SUDI)

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Respiratory pathogens in cases of sudden unexpected death in infants (SUDI) at Tygerberg Forensic Pathology Service Mortuary

inferred← citeshttps://doi.org/10.1016/j.immuni.2012.10.014openalex-snapshot

Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly

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Ontogeny of early life immunity

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Influence of the microbiota on vaccine effectiveness

inferred← citeshttps://doi.org/10.1016/j.jaci.2013.09.038openalex-snapshot

Pattern recognition receptor-mediated cytokine response in infants across 4 continents⋆

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Dectin-1 activation unlocks IL12A expression and reveals the TH1 potency of neonatal dendritic cells

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Placental and intra-amniotic inflammation are associated with altered fetal immune responses at birth

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Lack of broad functional differences in immunity in fully vaccinated vs. unvaccinated children

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Cytokine profiling in healthy children shows association of age with cytokine concentrations

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Associations between salivary cytokines and oral health, age, and sex in healthy children

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The seroprevalence ofBordetella pertussisantibodies in adolescents in the Western Cape

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Assessing the safety of bioactive ingredients in infant formula that affect the immune system: recommendations from an expert panel

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Altered Innate Immune Development in HIV-Exposed Uninfected Infants

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Response to lipopolysaccharide in Octodon degus pups produces age‐related sickness behavior but does not have effects in juveniles

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Differential maturation trajectories of innate antiviral immunity in health and atopy

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Aşılar ve Mikrobiyota

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The Contribution of Non-Conventional T Cells and NK Cells in the Mycobacterial-Specific IFNγ Response in Bacille Calmette-Guérin (BCG)-Immunized Infants

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Plasmodium falciparumRTS,S vaccines and future development

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Malaria vaccine development: over 40 years of trials and tribulations

inferred← citeshttps://doi.org/10.3389/fimmu.2013.00081openalex-snapshot

Variation between Populations in the Innate Immune Response to Vaccine Adjuvants

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A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity

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Postnatal Innate Immune Development: From Birth to Adulthood

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Increased T Cell Differentiation and Cytolytic Function in Bangladeshi Compared to American Children

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Vaccine-Induced CD8+ T Cell Responses in Children: A Review of Age-Specific Molecular Determinants Contributing to Antigen Cross-Presentation

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Maternal imprinting and determinants of neonates’ immune function in the SEPAGES mother-child cohort

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Increasing JAK/STAT Signaling Function of Infant CD4+ T Cells during the First Year of Life

inferred← citeshttps://doi.org/10.3389/fped.2017.00255openalex-snapshot

Influence of Age and Other Factors on Cytokine Expression Profiles in Healthy Children—A Systematic Review

inferred← citeshttps://doi.org/10.3390/vaccines11030509openalex-snapshot

Molecular Determinants of the Early Life Immune Response to COVID-19 Infection and Immunization

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Sex-Differential Impact of Human Cytomegalovirus Infection on In Vitro Reactivity to Toll-Like Receptor 2, 4 and 7/8 Stimulation in Gambian Infants

inferred← citeshttps://doi.org/10.4049/jimmunol.1400062openalex-snapshot

Maturation of Innate Responses to Mycobacteria over the First Nine Months of Life

inferred← citeshttps://doi.org/10.4049/jimmunol.1400895openalex-snapshot

Single-Cell Analysis of Innate Cytokine Responses to Pattern Recognition Receptor Stimulation in Children across Four Continents

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Microbiota Influences Vaccine and Mucosal Adjuvant Efficacy

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