On the public citation graph
Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1
0 signed · 172 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/emmm.201201283openalex-snapshot
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis
inferredcites →https://doi.org/10.1002/jcb.23314openalex-snapshot
D-galactose induces necroptotic cell death in neuroblastoma cell lines
inferredcites →https://doi.org/10.1007/s10557-007-6035-1openalex-snapshot
Necrostatin: A Potentially Novel Cardioprotective Agent?
inferredcites →https://doi.org/10.1007/s11064-012-0791-4openalex-snapshot
Necrostatin-1 Suppresses Autophagy and Apoptosis in Mice Traumatic Brain Injury Model
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2012.09.021openalex-snapshot
Palmitate induces RIP1-dependent necrosis in RAW 264.7 cells
inferredcites →https://doi.org/10.1016/j.ceb.2009.12.003openalex-snapshot
Necroptosis as an alternative form of programmed cell death
inferredcites →https://doi.org/10.1016/j.cell.2009.07.006openalex-snapshot
RIP Kinases at the Crossroads of Cell Death and Survival
inferredcites →https://doi.org/10.1016/j.chom.2012.01.016openalex-snapshot
DAI/ZBP1/DLM-1 Complexes with RIP3 to Mediate Virus-Induced Programmed Necrosis that Is Targeted by Murine Cytomegalovirus vIRA
inferredcites →https://doi.org/10.1016/j.critrevonc.2011.08.004openalex-snapshot
Necroptosis: An emerging form of programmed cell death
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2011.09.018openalex-snapshot
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/j.intimp.2012.08.003openalex-snapshot
RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy
inferredcites →https://doi.org/10.1016/j.kjms.2011.06.010openalex-snapshot
Glutathione‐S‐transferase enhances proliferation‐migration and protects against shikonin‐induced cell death in breast cancer cells
inferredcites →https://doi.org/10.1016/j.surg.2011.09.012openalex-snapshot
Necroptosis is a novel mechanism of radiation-induced cell death in anaplastic thyroid and adrenocortical cancers
inferredcites →https://doi.org/10.1016/j.taap.2008.12.012openalex-snapshot
Attenuation of cadmium-induced necrotic cell death by necrostatin-1: Potential necrostatin-1 acting sites
inferredcites →https://doi.org/10.1038/cdd.2012.90openalex-snapshot
TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation
inferredcites →https://doi.org/10.1038/cr.2008.86openalex-snapshot
Induction of apoptosis by shikonin through a ROS/JNK-mediated process in Bcr/Abl-positive chronic myelogenous leukemia (CML) cells
inferredcites →https://doi.org/10.1038/ki.2011.450openalex-snapshot
Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury
inferredcites →https://doi.org/10.1038/nchembio.83openalex-snapshot
Identification of RIP1 kinase as a specific cellular target of necrostatins
inferredcites →https://doi.org/10.1038/nchembio711openalex-snapshot
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
inferredcites →https://doi.org/10.1074/jbc.m111.319129openalex-snapshot
Inhibition of Autophagy Rescues Palmitic Acid-induced Necroptosis of Endothelial Cells
inferredcites →https://doi.org/10.1152/ajpcell.00353.2002openalex-snapshot
A novel method to determine specificity and sensitivity of the TUNEL reaction in the quantitation of apoptosis
inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0511openalex-snapshot
Shikonin circumvents cancer drug resistance by induction of a necroptotic death
inferredcites →https://doi.org/10.1167/iovs.04-0279openalex-snapshot
Phosphatidylinositol 3-Kinase (PI-3K)/Akt but Not PI-3K/p70 S6 Kinase Signaling Mediates IGF-1-Promoted Lens Epithelial Cell Survival
inferredcites →https://doi.org/10.1172/jci39987openalex-snapshot
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
inferredcites →https://doi.org/10.1179/016164109x12518779082273openalex-snapshot
Celastrol causes apoptosis and cell cycle arrest in rat glioma cells
inferredcites →https://doi.org/10.1186/1476-4598-9-135openalex-snapshot
Survival signalling and apoptosis resistance in glioblastomas: opportunities for targeted therapeutics
inferredcites →https://doi.org/10.1245/s10434-012-2324-4openalex-snapshot
Novel Multiple Apoptotic Mechanism of Shikonin in Human Glioma Cells
inferredcites →https://doi.org/10.1248/bpb.33.816openalex-snapshot
Shikonin Induces Apoptosis through Reactive Oxygen Species/Extracellular Signal-Regulated Kinase Pathway in Osteosarcoma Cells
inferredcites →https://doi.org/10.1371/journal.pone.0003909openalex-snapshot
Acute Myeloid Leukemia-Targeted Toxin Activates Both Apoptotic and Necroptotic Death Mechanisms
inferredcites →https://doi.org/10.1371/journal.pone.0023209openalex-snapshot
RIP1-Dependent and Independent Effects of Necrostatin-1 in Necrosis and T Cell Activation
inferredcites →https://doi.org/10.1371/journal.pone.0041945openalex-snapshot
Staurosporine Induces Necroptotic Cell Death under Caspase-Compromised Conditions in U937 Cells
inferredcites →https://doi.org/10.1634/theoncologist.12-12-1395openalex-snapshot
Proautophagic Drugs: A Novel Means to Combat Apoptosis-Resistant Cancers, with a Special Emphasis on Glioblastomas
inferredcites →https://doi.org/10.31083/ph.2012.1837openalex-snapshot
Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4185639openalex-extracted
ROS Overexpression Boosting Necroptosis Mediated by Mitochondrial Targeting Liposome for Cancer Apoptotic Resistance
inferred← citeshttps://doi.org/10.1002/2211-5463.13069openalex-snapshot
Osthole induces necroptosis via ROS overproduction in glioma cells
inferred← citeshttps://doi.org/10.1002/adma.202104704openalex-snapshot
Intracellular Condensates of Oligopeptide for Targeting Lysosome and Addressing Multiple Drug Resistance of Cancer
inferred← citeshttps://doi.org/10.1002/cbic.202000231openalex-snapshot
The Bulk Osteosarcoma and Osteosarcoma Stem Cell Activity of a Necroptosis‐Inducing Nickel(II)–Phenanthroline Complex
inferred← citeshttps://doi.org/10.1002/chem.202001578openalex-snapshot
Breast Cancer Stem Cell Potency of Nickel(II)‐Polypyridyl Complexes Containing Non‐steroidal Anti‐inflammatory Drugs
inferred← citeshttps://doi.org/10.1002/chem.202201259openalex-snapshot
A Rationally Designed Bimetallic Platinum (II)‐Ferrocene Antitumor Agent Induces Non‐Apoptotic Cell Death and Exerts in Vivo Efficacy
inferred← citeshttps://doi.org/10.1002/ddr.21936openalex-snapshot
Shikonin attenuates kidney tubular epithelial cells apoptosis, oxidative stress, and inflammatory response through nicotinamide adenine dinucleotide phosphate oxidase 4/PTEN pathway in acute kidney injury of sepsis model
inferred← citeshttps://doi.org/10.1002/ijc.29483openalex-snapshot
Shikonin and its derivatives inhibit the epidermal growth factor receptor signaling and synergistically kill glioblastoma cells in combination with erlotinib
inferred← citeshttps://doi.org/10.1002/ptr.70322openalex-snapshot
A Comprehensive Review on Necroptosis Inducing Phytochemicals for Cancer Therapy: Preclinical Evidence
inferred← citeshttps://doi.org/10.1007/978-981-99-7342-2_9openalex-snapshot
ROS, Redox Regulation, and Anticancer Therapy
inferred← citeshttps://doi.org/10.1007/s00018-016-2189-yopenalex-snapshot
An outline of necrosome triggers
inferred← citeshttps://doi.org/10.1007/s00018-016-2193-2openalex-snapshot
Cancer and necroptosis: friend or foe?
inferred← citeshttps://doi.org/10.1007/s10787-025-01666-5openalex-snapshot
A novel approach to glioblastoma multiforme treatment using modulation of key pathways by naturally occurring small molecules
inferred← citeshttps://doi.org/10.1007/s10863-017-9714-zopenalex-snapshot
Shikonin induces necroptosis by reactive oxygen species activation in nasopharyngeal carcinoma cell line CNE-2Z
inferred← citeshttps://doi.org/10.1007/s13277-016-5342-1openalex-snapshot
RIP1 upregulation promoted tumor progression by activating AKT/Bcl-2/BAX signaling and predicted poor postsurgical prognosis in HCC
inferred← citeshttps://doi.org/10.1016/b978-0-12-819937-4.00007-8openalex-snapshot
Induction of programmed necrosis by phytochemicals in colorectal cancer
inferred← citeshttps://doi.org/10.1016/bs.apcsb.2022.11.004openalex-snapshot
Mixed lineage kinase domain-like pseudokinase: Conventional (necroptosis) and unconventional (necroptosis-independent) functions and features
inferred← citeshttps://doi.org/10.1016/j.apsb.2020.01.007openalex-snapshot
Targeting necroptosis in anticancer therapy: mechanisms and modulators
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.03.020openalex-snapshot
Non-apoptotic cell death-based cancer therapy: Molecular mechanism, pharmacological modulators, and nanomedicine
inferred← citeshttps://doi.org/10.1016/j.bbcan.2019.01.006openalex-snapshot
The role of necroptosis in cancer: A double-edged sword?
inferred← citeshttps://doi.org/10.1016/j.bbcan.2023.188955openalex-snapshot
In what area of biology has a “new” type of cell death been discovered?
inferred← citeshttps://doi.org/10.1016/j.biopha.2016.04.015openalex-snapshot
RETRACTED: Investigation of the anti-glioma activity of Oviductus ranae protein hydrolysate
inferred← citeshttps://doi.org/10.1016/j.canlet.2015.11.044openalex-snapshot
Deoxypodophyllotoxin triggers parthanatos in glioma cells via induction of excessive ROS
inferred← citeshttps://doi.org/10.1016/j.canlet.2016.01.055openalex-snapshot
Pristimerin triggers AIF-dependent programmed necrosis in glioma cells via activation of JNK
inferred← citeshttps://doi.org/10.1016/j.canlet.2017.01.004openalex-snapshot
RIP1 and RIP3 contribute to shikonin-induced DNA double-strand breaks in glioma cells via increase of intracellular reactive oxygen species
inferred← citeshttps://doi.org/10.1016/j.canlet.2018.01.061openalex-snapshot
Non-apoptotic cell death in malignant tumor cells and natural compounds
inferred← citeshttps://doi.org/10.1016/j.canlet.2018.03.046openalex-snapshot
RIP1 and RIP3 contribute to shikonin-induced glycolysis suppression in glioma cells via increase of intracellular hydrogen peroxide
inferred← citeshttps://doi.org/10.1016/j.canlet.2019.04.033openalex-snapshot
Shikonin derivatives for cancer prevention and therapy
inferred← citeshttps://doi.org/10.1016/j.canlet.2019.09.007openalex-snapshot
MLKL contributes to shikonin-induced glioma cell necroptosis via promotion of chromatinolysis
inferred← citeshttps://doi.org/10.1016/j.canlet.2021.09.040openalex-snapshot
Stereotactic body radiation combined with oncolytic vaccinia virus induces potent anti-tumor effect by triggering tumor cell necroptosis and DAMPs
inferred← citeshttps://doi.org/10.1016/j.carpta.2021.100106openalex-snapshot
Biocompatible madecassoside encapsulated alginate chitosan nanoparticles, their anti-proliferative activity on C6 glioma cells
inferred← citeshttps://doi.org/10.1016/j.ccell.2015.08.012openalex-snapshot
Dual Targeting of the Autophagic Regulatory Circuitry in Gliomas with Repurposed Drugs Elicits Cell-Lethal Autophagy and Therapeutic Benefit
inferred← citeshttps://doi.org/10.1016/j.celld.2026.100008openalex-snapshot
Regulated cell death pathways in glioblastoma: Molecular mechanisms, natural compound modulation, and the emerging PANoptosis framework
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.01.014openalex-snapshot
2-Methoxy-6-acetyl-7-methyljuglone (MAM), a natural naphthoquinone, induces NO-dependent apoptosis and necroptosis by H2O2-dependent JNK activation in cancer cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.04.010openalex-snapshot
Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2020.03.026openalex-snapshot
2-Methoxy-6-acetyl-7-methyljuglone (MAM) induced programmed necrosis in glioblastoma by targeting NAD(P)H: Quinone oxidoreductase 1 (NQO1)
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.07.017openalex-snapshot
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors Necrostatin-1 (Nec-1) and 7-Cl-O-Nec-1 (Nec-1s) are potent inhibitors of NAD(P)H: Quinone oxidoreductase 1 (NQO1)
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105118openalex-snapshot
Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma
inferred← citeshttps://doi.org/10.1016/j.jelechem.2022.116663openalex-snapshot
Electrochemical characterization of shikonin and in-situ evaluation of interaction with DNA
inferred← citeshttps://doi.org/10.1016/j.jep.2019.111922openalex-snapshot
Extracts derived from a traditional Chinese herbal formula triggers necroptosis in ectocervical Ect1/E6E7 cells through activation of RIP1 kinase
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2020.107593openalex-snapshot
Induction of programmed necrosis: A novel anti-cancer strategy for natural compounds
inferred← citeshttps://doi.org/10.1016/j.phymed.2017.06.007openalex-snapshot
Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.redox.2023.102840openalex-snapshot
Comparative mechanistic study of RPE cell death induced by different oxidative stresses
inferred← citeshttps://doi.org/10.1016/j.redox.2026.104274openalex-snapshot
Ascorbate-driven quinone redox cycling as a pro-oxidant anticancer strategy
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.07.002openalex-snapshot
Therapeutic exploitation of necroptosis for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.semcdb.2014.08.010openalex-snapshot
Necroptosis, in vivo detection in experimental disease models
inferred← citeshttps://doi.org/10.1016/j.spen.2014.12.002openalex-snapshot
Targeting Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL): A Promising Therapeutic Strategy in Gliomas
inferred← citeshttps://doi.org/10.1016/j.talanta.2025.127886openalex-snapshot
Electrochemical bienzymatic biosensor for pyruvate kinase activity evaluation and inhibitor screening
inferred← citeshttps://doi.org/10.1016/j.tips.2016.12.005openalex-snapshot
Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis
inferred← citeshttps://doi.org/10.1016/s1674-6384(16)60026-6openalex-snapshot
Induction of Solasonine on Apoptosis of Human Breast Cancer Bcap-37 Cells through Mitochondria-Mediated Pathway
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c01174openalex-snapshot
Potent Ruthenium–Ferrocene Bimetallic Antitumor Antiangiogenic Agent That Circumvents Platinum Resistance: From Synthesis and Mechanistic Studies to In Vivo Evaluation in Zebrafish
inferred← citeshttps://doi.org/10.1021/acsami.3c18497openalex-snapshot
FePd Nanozyme- and SKN-Encapsulated Functional Lipid Nanoparticles for Cancer Nanotherapy via ROS-Boosting Necroptosis
inferred← citeshttps://doi.org/10.1021/acschemneuro.2c00405openalex-snapshot
Role of Necroptosis in Central Nervous System Diseases
inferred← citeshttps://doi.org/10.1021/acsmedchemlett.4c00207openalex-snapshot
Analysis of Antiangiogenic Potential and Cell Death Mechanism of a Kinetically Inert Platinum Antitumor Agent
inferred← citeshttps://doi.org/10.1021/acsnano.4c17090openalex-snapshot
Nanosized Shikonin Disrupts Tumor-Cell Mismatch Repair and Synergizes with Manganese to Sensitize Squamous Carcinoma to Immunotherapy
inferred← citeshttps://doi.org/10.1021/ja511978yopenalex-snapshot
Necroptosis-Inducing Rhenium(V) Oxo Complexes
inferred← citeshttps://doi.org/10.1038/aps.2017.112openalex-snapshot
Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation
inferred← citeshttps://doi.org/10.1038/cddis.2017.217openalex-snapshot
Cycloheximide promotes paraptosis induced by inhibition of cyclophilins in glioblastoma multiforme
inferred← citeshttps://doi.org/10.1038/ki.2014.388openalex-snapshot
Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats
inferred← citeshttps://doi.org/10.1038/mto.2016.20openalex-snapshot
N-end rule pathway inhibition assists colon tumor regression via necroptosis
inferred← citeshttps://doi.org/10.1038/nrm3737openalex-snapshot
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
inferred← citeshttps://doi.org/10.1038/s41392-024-01823-2openalex-snapshot
Tumor biomarkers for diagnosis, prognosis and targeted therapy
inferred← citeshttps://doi.org/10.1038/s41418-018-0214-4openalex-snapshot
Comparing the effects of different cell death programs in tumor progression and immunotherapy
inferred← citeshttps://doi.org/10.1038/s41419-019-1416-5openalex-snapshot
Dexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis
inferred← citeshttps://doi.org/10.1038/s41419-022-05524-yopenalex-snapshot
TRAF6 regulates the abundance of RIPK1 and inhibits the RIPK1/RIPK3/MLKL necroptosis signaling pathway and affects the progression of colorectal cancer
inferred← citeshttps://doi.org/10.1038/s41420-023-01421-1openalex-snapshot
A bibliometric analysis of ferroptosis, necroptosis, pyroptosis, and cuproptosis in cancer from 2012 to 2022
inferred← citeshttps://doi.org/10.1038/s41598-022-19066-yopenalex-snapshot
Cyclophilin A contributes to shikonin-induced glioma cell necroptosis and promotion of chromatinolysis
inferred← citeshttps://doi.org/10.1038/s41598-023-40669-6openalex-snapshot
The amide derivative of anticopalic acid induces non-apoptotic cell death in triple-negative breast cancer cells by inhibiting FAK activation
inferred← citeshttps://doi.org/10.1038/s41598-024-69888-1openalex-snapshot
Combination chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood–brain–barrier in a glioblastoma model
inferred← citeshttps://doi.org/10.1038/srep38267openalex-snapshot
Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species
inferred← citeshttps://doi.org/10.1039/d0ta00459fopenalex-snapshot
Sustainable electric power generation from live anaerobic digestion of sugar industry effluents using microbial fuel cells
inferred← citeshttps://doi.org/10.1055/s-0033-1350934openalex-snapshot
Pharmacological Properties of Shikonin – A Review of Literature since 2002
inferred← citeshttps://doi.org/10.1080/01902148.2017.1384083openalex-snapshot
Necrostatin-1 attenuates lipopolysaccharide-induced acute lung injury in mice
inferred← citeshttps://doi.org/10.1080/15548627.2017.1386359openalex-snapshot
Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance
inferred← citeshttps://doi.org/10.1080/17435889.2025.2504322openalex-snapshot
Preparation of surface-modified PLGA nanoparticles containing carbon quantum dots: insights from C6 cell line assays
inferred← citeshttps://doi.org/10.1089/ars.2017.7376openalex-snapshot
Inhibition of Lung Cancer by 2-Methoxy-6-Acetyl-7-Methyljuglone Through Induction of Necroptosis by Targeting Receptor-Interacting Protein 1
inferred← citeshttps://doi.org/10.1093/jmcb/mjaa055openalex-snapshot
The molecular mechanisms of MLKL-dependent and MLKL-independent necrosis
inferred← citeshttps://doi.org/10.1093/mtomcs/mfac072openalex-snapshot
Ursolic acid-piperazine-dithiocarbamate ruthenium(II) polypyridyl complexes induced necroptosis in MGC-803 cells
inferred← citeshttps://doi.org/10.1093/toxres/tfab107openalex-snapshot
Molecular mechanism of shikonin inhibiting tumor growth and potential application in cancer treatment
inferred← citeshttps://doi.org/10.1111/jfbc.13387openalex-snapshot
Tetrandrine inhibits cell migration and invasion in human nasopharyngeal carcinoma NPC‐TW 039 cells through inhibiting MAPK and RhoA signaling pathways
inferred← citeshttps://doi.org/10.1128/mbio.01456-22openalex-snapshot
TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
inferred← citeshttps://doi.org/10.1155/2024/1348269openalex-snapshot
Shikonin Induces Glioma Necroptosis, Stemness Decline, and Impedes (Immuno)Proteasome Activity
inferred← citeshttps://doi.org/10.1186/1471-2407-13-580openalex-snapshot
The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis
inferred← citeshttps://doi.org/10.1186/s12868-025-00956-6openalex-snapshot
Shikonin inhibits epithelial-mesenchymal transition in glioblastoma cells by upregulating p53 and promoting miR-361-5p level to suppress ZEB1 expression
inferred← citeshttps://doi.org/10.1186/s12885-018-5220-xopenalex-snapshot
Shikonin inhibits cancer cell cycling by targeting Cdc25s
inferred← citeshttps://doi.org/10.1186/s12943-019-1029-8openalex-snapshot
The role of necroptosis in cancer biology and therapy
inferred← citeshttps://doi.org/10.1186/s12967-017-1223-7openalex-snapshot
Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells
inferred← citeshttps://doi.org/10.1186/s13020-019-0270-9openalex-snapshot
Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine
inferred← citeshttps://doi.org/10.1186/s13046-018-0976-zopenalex-snapshot
Bypassing drug resistance by triggering necroptosis: recent advances in mechanisms and its therapeutic exploitation in leukemia
inferred← citeshttps://doi.org/10.1248/cpb.c19-00851openalex-snapshot
11-Methoxytabersonine Induces Necroptosis with Autophagy through AMPK/mTOR and JNK Pathways in Human Lung Cancer Cells
inferred← citeshttps://doi.org/10.12659/msm.919739openalex-snapshot
Necrostatin-1 Alleviates Bleomycin-Induced Pulmonary Fibrosis and Extracellular Matrix Expression in Interstitial Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1371/journal.pone.0343458openalex-snapshot
Expression of Concern: Shikonin Kills Glioma Cells through Necroptosis Mediated by RIP-1
inferred← citeshttps://doi.org/10.1590/1414-431x20144310openalex-snapshot
The role of necroptosis in neurosurgical diseases
inferred← citeshttps://doi.org/10.1637/11732-073017-reg.1openalex-snapshot
The Role of Necroptosis, Apoptosis, and Inflammation in Fowl Cholera–Associated Liver Injury in a Chicken Model
inferred← citeshttps://doi.org/10.18502/kme.v2i3.11877openalex-snapshot
Curcuma Longa Herbs: A Mechanism to Increase the Innate Immune Response Through a Pharmacological System Approach
inferred← citeshttps://doi.org/10.18632/aging.103844openalex-snapshot
Shikonin overcomes drug resistance and induces necroptosis by regulating the miR-92a-1-5p/MLKL axis in chronic myeloid leukemia
inferred← citeshttps://doi.org/10.18632/oncotarget.10548openalex-snapshot
Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3960491/v1openalex-snapshot
Combinatorial chemotherapy via poloxamer 188 surface-modified PLGA nanoparticles that traverse the blood-brain-barrier in a glioblastoma model
inferred← citeshttps://doi.org/10.21427/d7632vopenalex-snapshot
Novel Therapeutic Approaches to Induce Autophagy in Brain Cancer
inferred← citeshttps://doi.org/10.2147/ijn.s435104openalex-snapshot
Sonosensitizer Nanoplatforms Augmented Sonodynamic Therapy-Sensitizing Shikonin-Induced Necroptosis Against Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.2147/ijn.s51880openalex-snapshot
Shikonin-loaded antibody-armed nanoparticles for targeted therapy of ovarian cancer
inferred← citeshttps://doi.org/10.2147/ott.s200740openalex-snapshot
Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression
inferred← citeshttps://doi.org/10.2147/ott.s242567openalex-snapshot
Bufalin Induces Glioma Cell Death by Apoptosis or Necroptosis
inferred← citeshttps://doi.org/10.2174/0929867326666190809221332openalex-snapshot
Phytochemical-Mediated Glioma Targeted Treatment: Drug Resistance and Novel Delivery Systems
inferred← citeshttps://doi.org/10.2174/1389202917666160803150639openalex-snapshot
Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells
inferred← citeshttps://doi.org/10.2174/1871520623666230701000338openalex-snapshot
Shikonin Causes Non-apoptotic Cell Death in B16F10 Melanoma
inferred← citeshttps://doi.org/10.3389/fimmu.2021.742370openalex-snapshot
Mycobacterium tuberculosis Exploits Focal Adhesion Kinase to Induce Necrotic Cell Death and Inhibit Reactive Oxygen Species Production
inferred← citeshttps://doi.org/10.3389/fonc.2020.616952openalex-snapshot
Caspase-Independent Regulated Necrosis Pathways as Potential Targets in Cancer Management
inferred← citeshttps://doi.org/10.3389/fonc.2022.855434openalex-snapshot
Clinical and Biological Significance of a Necroptosis-Related Gene Signature in Glioma
inferred← citeshttps://doi.org/10.3389/fonc.2022.899443openalex-snapshot
The Identification of Necroptosis-Related Subtypes, the Construction of a Prognostic Model, and the Characterization of the Tumor Microenvironment in Gliomas
inferred← citeshttps://doi.org/10.3389/fphar.2020.01009openalex-snapshot
Advances in Molecular Mechanisms for Traditional Chinese Medicine Actions in Regulating Tumor Immune Responses
inferred← citeshttps://doi.org/10.3389/fphar.2021.725136openalex-snapshot
Cannabidiol Induces Apoptosis and Perturbs Mitochondrial Function in Human and Canine Glioma Cells
inferred← citeshttps://doi.org/10.3389/fphar.2023.1219362openalex-snapshot
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect
inferred← citeshttps://doi.org/10.3390/antiox10111831openalex-snapshot
Shikonin Induced Program Cell Death through Generation of Reactive Oxygen Species in Renal Cancer Cells
inferred← citeshttps://doi.org/10.3390/app10134439openalex-snapshot
Label-Free Classification of Apoptosis, Ferroptosis and Necroptosis Using Digital Holographic Cytometry
inferred← citeshttps://doi.org/10.3390/biomedicines9101353openalex-snapshot
Targeting Drug Chemo-Resistance in Cancer Using Natural Products
inferred← citeshttps://doi.org/10.3390/books978-3-0365-7040-2openalex-snapshot
Recent Progress of Nanomedicine and Targeted Drug Delivery for Cancer Treatment
inferred← citeshttps://doi.org/10.3390/cancers13020304openalex-snapshot
Natural Products as Inducers of Non-Canonical Cell Death: A Weapon against Cancer
inferred← citeshttps://doi.org/10.3390/cancers14051114openalex-snapshot
Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway
inferred← citeshttps://doi.org/10.3390/ijms161023823openalex-snapshot
RETRACTED: Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal Medicine
inferred← citeshttps://doi.org/10.3390/ijms23137184openalex-snapshot
Mechanism of Bile Acid-Induced Programmed Cell Death and Drug Discovery against Cancer: A Review
inferred← citeshttps://doi.org/10.3390/ijms26051942openalex-snapshot
The Small Molecules of Plant Origin with Anti-Glioma Activity
inferred← citeshttps://doi.org/10.3390/molecules23123304openalex-snapshot
Bulnesia sarmientoi Supercritical Fluid Extract Exhibits Necroptotic Effects and Anti-Metastatic Activity on Lung Cancer Cells
inferred← citeshttps://doi.org/10.3390/molecules25010192openalex-snapshot
Inhibition of TGF-β Signaling in Gliomas by the Flavonoid Diosmetin Isolated from Dracocephalum peregrinum L.
inferred← citeshttps://doi.org/10.3390/ph16020207openalex-snapshot
Harnessing Folate-Functionalized Nasal Delivery of Dox–Erlo-Loaded Biopolymeric Nanoparticles in Cancer Treatment: Development, Optimization, Characterization, and Biodistribution Analysis
inferred← citeshttps://doi.org/10.3390/toxins6051559openalex-snapshot
In Vitro Induction of Erythrocyte Phosphatidylserine Translocation by the Natural Naphthoquinone Shikonin
inferred← citeshttps://doi.org/10.3892/ijo.2014.2804openalex-snapshot
Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells
inferred← citeshttps://doi.org/10.3892/ol.2017.6285openalex-snapshot
Exploitation of necroptosis for treatment of caspase-compromised cancers
inferred← citeshttps://doi.org/10.4062/biomolther.2014.046openalex-snapshot
Harnessing of Programmed Necrosis for Fighting against Cancers
inferred← citeshttps://doi.org/10.4062/biomolther.2015.145openalex-snapshot
Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells
inferred← citeshttps://doi.org/10.4149/neo_2018_180710n466openalex-snapshot
Receptor interacting protein kinase 3 promotes cisplatin-induced necroptosis in apoptosis-resistant HepG2/DDP cells
inferred← citeshttps://doi.org/10.5246/jcps.2020.01.001openalex-snapshot
Emodin and shikonin (quinones): an overview of their chemistry, plant sources, pharmacology and cytotoxic activities against lung cancer
inferred← citeshttps://doi.org/10.70675/14750b73za612z432ezbf7cz5b72ea09e2e5openalex-snapshot
Caractérisation de nouveaux inhibiteurs de la kinase RIPK1 et de la nécroptose
inferred← citeshttps://doi.org/10.7190/shu-thesis-00623openalex-snapshot
Enhancement of Breast Cancer Chemotherapy and Radiotherapy Responses by Modulation of Ferroptosis
inferred← citeshttps://doi.org/10.7314/apjcp.2014.15.15.6321openalex-snapshot
Activation of JNK/p38 Pathway is Responsible for α-Methyl-n-butylshikonin Induced Mitochondria-Dependent Apoptosis in SW620 Human Colorectal Cancer Cells
inferred← citeshttps://doi.org/10.7314/apjcp.2015.16.16.7261openalex-snapshot
Shikonin Induced Necroptosis via Reactive Oxygen Species in the T-47D Breast Cancer Cell Line
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.