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Global Gene Expression Analysis Reveals a Link between NDRG1 and Vesicle Transport

https://doi.org/10.1371/journal.pone.0087268
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/glia.20386openalex-snapshot
Schwann cells and the pathogenesis of inherited motor and sensory neuropathies (Charcot‐Marie‐Tooth disease)
inferredcites →https://doi.org/10.1002/mc.1069openalex-snapshot
Regulation of the differentiation‐related gene Drg‐1 during mouse skin carcinogenesis
inferredcites →https://doi.org/10.1002/prot.10083openalex-snapshot
Identification of a novel class in the α/β hydrolase fold superfamily: The N‐myc differentiation‐related proteins
inferredcites →https://doi.org/10.1006/geno.2000.6496openalex-snapshot
Characterization of the Human NDRG Gene Family: A Newly Identified Member, NDRG4, Is Specifically Expressed in Brain and Heart
inferredcites →https://doi.org/10.1007/bf02686013openalex-snapshot
A retroviral vector for siRNA expression in mammalian cells
inferredcites →https://doi.org/10.1007/s00018-009-8778-2openalex-snapshot
Activation of CD47 receptors causes histamine secretion from mast cells
inferredcites →https://doi.org/10.1007/s00418-002-0460-9openalex-snapshot
Expression of NDRG1, a differentiation-related gene, in human tissues
inferredcites →https://doi.org/10.1007/s12035-009-8071-2openalex-snapshot
Myelin Proteomics: Molecular Anatomy of an Insulating Sheath
inferredcites →https://doi.org/10.1016/j.canlet.2010.05.020openalex-snapshot
Hypoxia and retinoic acid-inducible NDRG1 expression is responsible for doxorubicin and retinoic acid resistance in hepatocellular carcinoma cells
inferredcites →https://doi.org/10.1016/j.cca.2007.09.010openalex-snapshot
A quantitative analysis of N-myc downstream regulated gene 2 (NDRG 2) in human tissues and cell lysates by reverse-phase protein microarray
inferredcites →https://doi.org/10.1016/j.nbd.2011.01.030openalex-snapshot
Ndrg1 in development and maintenance of the myelin sheath
inferredcites →https://doi.org/10.1016/j.nmd.2007.06.024openalex-snapshot
G.O.3 Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H
inferredcites →https://doi.org/10.1016/j.surg.2010.11.002openalex-snapshot
N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo
inferredcites →https://doi.org/10.1016/s0006-291x(03)00942-2openalex-snapshot
Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells
inferredcites →https://doi.org/10.1016/s0076-6879(99)03014-1openalex-snapshot
[12] DNA arrays for analysis of gene expression
inferredcites →https://doi.org/10.1016/s0898-6568(03)00093-7openalex-snapshot
Live and let die: regulatory mechanisms in Fas-mediated apoptosis
inferredcites →https://doi.org/10.1016/s0955-0674(02)00349-6openalex-snapshot
Regulating the actin cytoskeleton during vesicular transport
inferredcites →https://doi.org/10.1023/a:1024918328162openalex-snapshot
The growth-inhibitory Ndrg1 gene is a Myc negative target in human neuroblastomas and other cell types with overexpressed N- or c-myc
inferredcites →https://doi.org/10.1038/nn.2273openalex-snapshot
Endoplasmic reticulum stress in disorders of myelinating cells
inferredcites →https://doi.org/10.1038/sj.bjc.6605208openalex-snapshot
Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies
inferredcites →https://doi.org/10.1038/sj.onc.1207734openalex-snapshot
Role of the putative tumor metastasis suppressor gene Drg-1 in breast cancer progression
inferredcites →https://doi.org/10.1046/j.1529-8027.2001.01008-16.xopenalex-snapshot
N‐MYC Downstream‐Regulated Gene 1 Is Mutated In Hereditary Motor And Sensory Neuropathy‐LOM
inferredcites →https://doi.org/10.1073/pnas.091062498openalex-snapshot
Significance analysis of microarrays applied to the ionizing radiation response
inferredcites →https://doi.org/10.1073/pnas.95.25.14863openalex-snapshot
Cluster analysis and display of genome-wide expression patterns
inferredcites →https://doi.org/10.1073/pnas.96.25.14517openalex-snapshot
Identification and classification of p53-regulated genes
inferredcites →https://doi.org/10.1074/jbc.271.47.29659openalex-snapshot
Homocysteine-respondent Genes in Vascular Endothelial Cells Identified by Differential Display Analysis
inferredcites →https://doi.org/10.1074/jbc.m007039200openalex-snapshot
A New Family of Cdc42 Effector Proteins, CEPs, Function in Fibroblast and Epithelial Cell Shape Changes
inferredcites →https://doi.org/10.1074/jbc.m400386200openalex-snapshot
NDRG1 Is Necessary for p53-dependent Apoptosis
inferredcites →https://doi.org/10.1074/jbc.m606248200openalex-snapshot
Identification of a DOCK180-related Guanine Nucleotide Exchange Factor That Is Capable of Mediating a Positive Feedback Activation of Cdc42
inferredcites →https://doi.org/10.1074/mcp.m600249-mcp200openalex-snapshot
Proteomics Analysis of the Interactome of N-myc Downstream Regulated Gene 1 and Its Interactions with the Androgen Response Program in Prostate Cancer Cells
inferredcites →https://doi.org/10.1083/jcb.200501157openalex-snapshot
Coatomer-bound Cdc42 regulates dynein recruitment to COPI vesicles
inferredcites →https://doi.org/10.1083/jcb.200509022openalex-snapshot
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites
inferredcites →https://doi.org/10.1086/302978openalex-snapshot
N-myc Downstream-Regulated Gene 1 Is Mutated in Hereditary Motor and Sensory Neuropathy–Lom
inferredcites →https://doi.org/10.1086/518428openalex-snapshot
Mutations in FGD4 Encoding the Rho GDP/GTP Exchange Factor FRABIN Cause Autosomal Recessive Charcot-Marie-Tooth Type 4H
inferredcites →https://doi.org/10.1091/mbc.e08-09-0925openalex-snapshot
Fas Death Receptor Enhances Endocytic Membrane Traffic Converging into the Golgi Region
inferredcites →https://doi.org/10.1091/mbc.e09-01-0057openalex-snapshot
Regulation of Cell Death by Recycling Endosomes and Golgi Membrane Dynamics via a Pathway Involving Src-family kinases, Cdc42 and Rab11a
inferredcites →https://doi.org/10.1093/brain/121.3.399openalex-snapshot
Hereditary motor and sensory neuropathy--Lom, a novel demyelinating neuropathy associated with deafness in gypsies. Clinical, electrophysiological and nerve biopsy findings
inferredcites →https://doi.org/10.1096/fj.05-5376comopenalex-snapshot
Novel guanine nucleotide exchange factor GEFmeso of Drosophila melanogaster interacts with Ral and Rho GTPase Cdc42
inferredcites →https://doi.org/10.1096/fj.09-151464openalex-snapshot
The N‐myc downstream regulated gene (NDRG) family: diverse functions, multiple applications
inferredcites →https://doi.org/10.1111/j.1471-4159.2006.04066.xopenalex-snapshot
Characterization of the localization and function of NECAP 1 in neurons
inferredcites →https://doi.org/10.1111/j.1745-7270.2008.00434.xopenalex-snapshot
NDRG2: a Myc-repressed gene involved in cancer and cell stress
inferredcites →https://doi.org/10.1128/mcb.24.9.3949-3956.2004openalex-snapshot
Ndrg1-Deficient Mice Exhibit a Progressive Demyelinating Disorder of Peripheral Nerves
inferredcites →https://doi.org/10.1152/ajpcell.00547.2006openalex-snapshot
p53-Dependent NDRG1 expression induces inhibition of intestinal epithelial cell proliferation but not apoptosis after polyamine depletion
inferredcites →https://doi.org/10.1158/0008-5472.can-04-0107openalex-snapshot
Cell-Type-Specific Responses to Chemotherapeutics in Breast Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-04-1623openalex-snapshot
PTEN Up-Regulates the Tumor Metastasis Suppressor Gene Drg-1 in Prostate and Breast Cancer
inferredcites →https://doi.org/10.1182/blood-2004-05-1866openalex-snapshot
Iron chelators with high antiproliferative activity up-regulate the expression of a growth inhibitory and metastasis suppressor gene: a link between iron metabolism and proliferation
inferredcites →https://doi.org/10.1186/1471-2105-6-168openalex-snapshot
High-Throughput GoMiner, an 'industrial-strength' integrative gene ontology tool for interpretation of multiple-microarray experiments, with application to studies of Common Variable Immune Deficiency (CVID)
inferredcites →https://doi.org/10.1186/1471-2156-5-27openalex-snapshot
Hypoxia upregulates the expression of the NDRG1 gene leading to its overexpression in various human cancers
inferredcites →https://doi.org/10.1186/1756-0500-7-157openalex-snapshot
In silico prediction of protein-protein interactions in human macrophages
inferredcites →https://doi.org/10.1186/gb-2003-4-4-r28openalex-snapshot
GoMiner: a resource for biological interpretation of genomic and proteomic data
inferredcites →https://doi.org/10.1248/bpb.27.624openalex-snapshot
N-Myc Downregulated Gene 1 Is a Phosphorylated Protein in Mast Cells
inferredcites →https://doi.org/10.1371/journal.pmed.0030047openalex-snapshot
Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
inferredcites →https://doi.org/10.1371/journal.pone.0054547openalex-snapshot
A Gly98Val Mutation in the N-Myc Downstream Regulated Gene 1 (NDRG1) in Alaskan Malamutes with Polyneuropathy
inferredcites →https://doi.org/10.1371/journal.pone.0075473openalex-snapshot
The Expression and Localization of N-Myc Downstream-Regulated Gene 1 in Human Trophoblasts
inferredcites →https://doi.org/10.2144/05381mt02openalex-snapshot
High Reproducibility using Sodium Hydroxide-Stripped Long Oligonucleotide DNA Microarrays
inferredcites →https://doi.org/10.3390/ijms14047089openalex-snapshot
Roles of Rho GTPases in Intracellular Transport and Cellular Transformation

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4676945openalex-extracted
THER: Integrative Web Tool for Tumor Hypoxia Exploration and Research
inferred← citeshttps://doi.org/10.1002/1878-0261.12059openalex-snapshot
The prostate metastasis suppressor gene NDRG1 differentially regulates cell motility and invasion
inferred← citeshttps://doi.org/10.1002/humu.23309openalex-snapshot
Identification and functional characterization of two missense mutations in NDRG1 associated with Charcot‐Marie‐Tooth disease type 4D
inferred← citeshttps://doi.org/10.1007/978-3-030-69951-2_4openalex-snapshot
Simultaneous Clustering of Multiple Gene Expression Datasets for Pattern Discovery
inferred← citeshttps://doi.org/10.1007/s12024-023-00681-8openalex-snapshot
Potential biomarkers in hypoglycemic brain injury
inferred← citeshttps://doi.org/10.1016/j.bbadis.2019.04.007openalex-snapshot
The metastasis suppressor, NDRG1, differentially modulates the endoplasmic reticulum stress response
inferred← citeshttps://doi.org/10.1016/j.brainres.2016.10.012openalex-snapshot
Antisera against Neisseria gonorrhoeae cross-react with specific brain proteins of the common marmoset monkey and other nonhuman primate species
inferred← citeshttps://doi.org/10.1016/j.cjca.2024.10.011openalex-snapshot
NDRG1 Regulates Iron Metabolism and Inhibits Pathologic Cardiac Hypertrophy
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2019.05.020openalex-snapshot
Pharmacological targeting and the diverse functions of the metastasis suppressor, NDRG1, in cancer
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.136978openalex-snapshot
The dual role of autophagy during porcine reproductive and respiratory syndrome virus infection: A review
inferred← citeshttps://doi.org/10.1016/j.jtha.2024.02.008openalex-snapshot
Coagulation factor V in breast cancer: a p53-regulated tumor suppressor and predictive marker for treatment response to chemotherapy
inferred← citeshttps://doi.org/10.1016/j.nano.2019.102014openalex-snapshot
Interfering with endolysosomal trafficking enhances release of bioactive exosomes
inferred← citeshttps://doi.org/10.1016/j.nmd.2020.11.010openalex-snapshot
Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D
inferred← citeshttps://doi.org/10.1016/j.placenta.2015.05.009openalex-snapshot
N-myc downstream-regulated gene 1 (NDRG1) mediates pomegranate juice protection from apoptosis in hypoxic BeWo cells but not in primary human trophoblasts
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2019.07.013openalex-snapshot
Genome-wide association studies for the number of animals born alive and dead in duroc pigs
inferred← citeshttps://doi.org/10.1096/fj.202100443ropenalex-snapshot
Differential expression and hypoxia‐mediated regulation of the N‐myc downstream regulated gene family
inferred← citeshttps://doi.org/10.1101/2020.12.16.422782openalex-snapshot
Hypoxia Regulation of ndrgs
inferred← citeshttps://doi.org/10.1111/cpr.70053openalex-snapshot
THER: Integrative Web Tool for Tumour Hypoxia Exploration and Research
inferred← citeshttps://doi.org/10.1111/febs.15660openalex-snapshot
Crystal and solution structure of NDRG1, a membrane‐binding protein linked to myelination and tumour suppression
inferred← citeshttps://doi.org/10.1128/jvi.01166-17openalex-snapshot
N-Myc Downstream-Regulated Gene 1 Restricts Hepatitis C Virus Propagation by Regulating Lipid Droplet Biogenesis and Viral Assembly
inferred← citeshttps://doi.org/10.1128/mcb.00559-21openalex-snapshot
Aberrant Neuregulin 1/ErbB Signaling in Charcot-Marie-Tooth Type 4D Disease
inferred← citeshttps://doi.org/10.1177/1756284819858507openalex-snapshot
Characterization of the prognostic values of the NDRG family in gastric cancer
inferred← citeshttps://doi.org/10.1186/s12917-019-1872-2openalex-snapshot
Cell and context-dependent sorting of neuropathy-associated protein NDRG1 – insights from canine tissues and primary Schwann cell cultures
inferred← citeshttps://doi.org/10.1186/s12943-017-0673-0openalex-snapshot
In vitro downregulated hypoxia transcriptome is associated with poor prognosis in breast cancer
inferred← citeshttps://doi.org/10.1186/s13058-018-0980-4openalex-snapshot
NDRG1 regulates neutral lipid metabolism in breast cancer cells
inferred← citeshttps://doi.org/10.1186/s13578-024-01336-zopenalex-snapshot
Unraveling the protein kinase C/NDRG1 signaling network in breast cancer
inferred← citeshttps://doi.org/10.18632/oncotarget.24844openalex-snapshot
The role of oxidative stress in activity of anticancer thiosemicarbazones
inferred← citeshttps://doi.org/10.18632/oncotarget.28455openalex-snapshot
Deciphering the mechanisms of action of progesterone in breast cancer
inferred← citeshttps://doi.org/10.25692/acen.2019.1.7openalex-snapshot
Current view on phenotypic and genetic features of autosomal recessive inherited peripheral neuropathies
inferred← citeshttps://doi.org/10.33540/1547openalex-snapshot
Extracellular vesicle therapeutics: from mechanism to application in cardiac repair
inferred← citeshttps://doi.org/10.3389/fonc.2022.862216openalex-snapshot
Clinical Diagnostic and Prognostic Potential of NDRG1 and NDRG2 in Hepatocellular Carcinoma Patients
inferred← citeshttps://doi.org/10.3390/ijms26083582openalex-snapshot
Insight into the Regulation of NDRG1 Expression
inferred← citeshttps://doi.org/10.4103/1008-682x.170445openalex-snapshot
Proteomic signatures of infertile men with clinical varicocele and their validation studies reveal mitochondrial dysfunction leading to infertility
inferred← citeshttps://doi.org/10.70675/7e1e5b7az8259z4fc7z9367zc95716f2361fopenalex-snapshot
Génétique et physiopathologie de la maladie de Charcot-Marie-Tooth de type 4H
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