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Redox Proteomics of the Inflammatory Secretome Identifies a Common Set of Redoxins and Other Glutathionylated Proteins Released in Inflammation, Influenza Virus Infection and Oxidative Stress

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus
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Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal
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Glutathione deficiency is associated with impaired survival in HIV disease
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Thioltransferase (Glutaredoxin) Is Detected Within HIV-1 and Can Regulate the Activity of Glutathionylated HIV-1 Protease in Vitro
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HIV-1 Antiviral Activity of Recombinant Natural Killer Cell Enhancing Factors, NKEF-A and NKEF-B, Members of the Peroxiredoxin Family
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Key role of regulated upon activation normal T-cell expressed and secreted, nonstructural protein1 and myeloperoxidase in cytokine storm induced by influenza virus PR-8 (A/H1N1) infection in A549 bronchial epithelial cells
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p38 Mitogen-Activated Protein Kinase-Dependent Hyperinduction of Tumor Necrosis Factor Alpha Expression in Response to Avian Influenza Virus H5N1
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BI-DIRECTIONAL PROTEIN TRANSPORT BETWEEN THE ER AND GOLGI
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Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells
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TLRs and innate immunity
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The sixth sense: hematopoietic stem cells detect danger through purinergic signaling
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Immunoscreening of the extracellular proteome of colorectal cancer cells
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Characterization of the microheterogeneity of transthyretin in plasma and urine using SELDI-TOF-MS immunoassay.
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Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1
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S-Glutathionylation Impairs Signal Transducer and Activator of Transcription 3 Activation and Signaling
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Regulation of redox-sensitive exofacial protein thiols in CHO cells
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Cysteine Oxidation Targets Peroxiredoxins 1 and 2 for Exosomal Release through a Novel Mechanism of Redox-Dependent Secretion
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The Environmental Pollutant Cadmium Promotes Influenza Virus Replication in MDCK Cells by Altering Their Redox State
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Peroxiredoxin 1 Stimulates Secretion of Proinflammatory Cytokines by Binding to TLR4

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Positive Regulation of Interleukin-1 Beta Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation
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NRF2 Antioxidant Response and Interferon‐Stimulated Genes Are Differentially Expressed in SARS‐CoV‐2‐Positive Young Subjects
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Proteomic characterization of platelet gel releasate from adult peripheral and cord blood
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Proteomic Methods to Evaluate NOX-Mediated Redox Signaling
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Other Techniques for Oxidative Stress Assessment
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When safeguarding goes wrong: Impact of oxidative stress on protein homeostasis in health and neurodegenerative disorders
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Role of protein S-Glutathionylation in cancer progression and development of resistance to anti-cancer drugs
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Anti-inflammatory effects of rosmarinic acid-4-O-β-D-glucoside in reducing acute lung injury in mice infected with influenza virus
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Estrogen deficiency alters peroxiredoxin levels in the bone and leads to redox signaling dysregulation in a rat menopause model
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The redox-responsive roles of intermediate filaments in cellular stress detection, integration and mitigation
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Positive Regulation of Interleukin-1β Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation
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Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins
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Quantitative measures for redox signaling
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Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis
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Susceptibility of the patients infected with Sars-Cov2 to oxidative stress and possible interplay with severity of the disease
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Release of redox enzymes and micro-RNAs in extracellular vesicles, during infection and inflammation
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Global blood miRNA profiling unravels early signatures of immunogenicity of Ebola vaccine rVSVΔG-ZEBOV-GP
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Mapping the phenotypic repertoire of the cytoplasmic 2-Cys peroxiredoxin – Thioredoxin system. 1. Understanding commonalities and differences among cell types
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Paracrine regulation and improvement of β-cell function by thioredoxin
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Effectiveness of Periodic Treatment of Quercetin against Influenza A Virus H1N1 through Modulation of Protein Expression
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Regioselective IBX-Mediated Synthesis of Coumarin Derivatives with Antioxidant and Anti-influenza Activities
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Redox Proteomes in Human Physiology and Disease Mechanisms
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Strain-dependent glutathionylation of fibronectin fibers impacts mechano-chemical behavior and primes an integrin switch
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Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5
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Development of ‘Redox Arrays’ for identifying novel glutathionylated proteins in the secretome
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Glutathionylation of the Active Site Cysteines of Peroxiredoxin 2 and Recycling by Glutaredoxin
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Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine
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Evolution, role in inflammation, and redox control of leaderless secretory proteins
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Inflammation-induced reactive nitrogen species cause proteasomal degradation of dimeric peroxiredoxin-1 in a mouse macrophage cell line
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Update on Proteomic approaches to uncovering virus-induced protein alterations and virus –host protein interactions during the progression of viral infection
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Clinical Relevance of Biomarkers of Oxidative Stress
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Redox Proteomics Applied to the Thiol Secretome
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Oxidative Stress and Inflammation Induced by Environmental and Psychological Stressors: A Biomarker Perspective
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Peri/Epicellular Thiol Oxidoreductases as Mediators of Extracellular Redox Signaling
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Influenza virus replication is affected by glutaredoxin1‐mediated protein deglutathionylation
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Bisphenol A Exposure Impairs Epididymal Development during the Peripubertal Period of Rats: Inflammatory Profile and Tissue Changes
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Vimentin S‐glutathionylation at Cys328 inhibits filament elongation and induces severing of mature filaments in vitro
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Redox Regulation of Inflammatory Processes Is Enzymatically Controlled
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Redox‐Dependent Activation of Matrix Metalloproteinases Regulates Influenza A Virus Replication in Neuronal Cells
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Redox control in the pathophysiology of influenza virus infection
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Thiol switches in membrane proteins - Extracellular redox regulation in cell biology
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2-Acetylamino-3-[4-(2-acetylamino-2-carboxyethylsulfanylcarbonylamino) phenyl carbamoylsulfanyl] propionic acid, a glutathione reductase inhibitor, induces G2/M cell cycle arrest through generation of thiol oxidative stress in human esophageal cancer cells
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Longitudinal serum proteomics analyses reveal discriminatory biomarkers for influenza and coronavirus infections
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Protein thiol oxidoreductas and allergic airways disease
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Preoperative circulating peroxiredoxin 1 levels as a predictor of non-alcoholic fatty liver disease remission after laparoscopic bariatric surgery
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Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties
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Severity of Systemic Inflammatory Response Syndrome Affects the Blood Levels of Circulating Inflammatory-Relevant MicroRNAs
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Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice
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Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice
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Thiol Modifications in the Extracellular Space—Key Proteins in Inflammation and Viral Infection
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Peroxiredoxins—The Underrated Actors during Virus-Induced Oxidative Stress
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Changing Perspectives from Oxidative Stress to Redox Signaling—Extracellular Redox Control in Translational Medicine
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Redox-Modulating Agents in the Treatment of Viral Infections
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Vimentin as a Multifaceted Player and Potential Therapeutic Target in Viral Infections
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PRDX2 Knockdown Inhibits Extracellular Matrix Synthesis of Chondrocytes by Inhibiting Wnt5a/YAP1/CTGF and Activating IL-6/JAK2/STAT3 Pathways in Deer Antler
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Role of Glutathionylation in Infection and Inflammation
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Phytochemical Composition and Cytoprotective Properties of the Endemic Sideritis sipylea Boiss Greek Species: A Valorization Study
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Multi-Omics Studies towards Novel Modulators of Influenza A Virus–Host Interaction
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Detection of Nuclear Protein Profile Changes by Human Metapneumovirus M2-2 Protein Using Quantitative Differential Proteomics
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Infectious mononucleosis and hepatic function
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Low uric acid level increases the risk of infectious mononucleosis and this effect is more pronounced in women
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Additional file 1 of Coordinated reprogramming of renal cancer transcriptome, metabolome and secretome associates with immune tumor infiltration
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Additional file 2 of Coordinated reprogramming of renal cancer transcriptome, metabolome and secretome associates with immune tumor infiltration
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