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The Impact of Selective Dopamine D2, D3 and D4 Ligands on the Rat Gambling Task

https://doi.org/10.1371/journal.pone.0136267

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What this work says

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3-[[4-(4-Chlorophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine: An Antagonist with High Affinity and Selectivity for the Human Dopamine D4 Receptor

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Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

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Localization of dopamine D4 receptors in GABAergic neurons of the primate brain

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Dopamine Receptor Gene Expression in the Human Medial Temporal Lobe

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Blockade of Dopamine D4 Receptors Attenuates Reinstatement of Extinguished Nicotine-Seeking Behavior in Rats

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Selective Blockade of Dopamine D3 Receptors Enhances while D2 Receptor Antagonism Impairs Social Novelty Discrimination and Novel Object Recognition in Rats: A Key Role for the Prefrontal Cortex

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Dopamine D3 Receptors in the Basolateral Amygdala and the Lateral Habenula Modulate Cue-Induced Reinstatement of Nicotine Seeking

inferredcites →https://doi.org/10.1038/sj.npp.1301295openalex-snapshot

A D2 Antagonist Enhances the Rewarding and Priming Effects of a Gambling Episode in Pathological Gamblers

inferredcites →https://doi.org/10.1073/pnas.89.24.12093openalex-snapshot

Photoreceptors of mouse retinas possess D4 receptors coupled to adenylate cyclase.

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Selective dopamine D4 receptor agonist (A-412997) improves cognitive performance and stimulates motor activity without influencing reward-related behaviour in rat

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Genetics of dopamine receptors and drug addiction: a comprehensive review

inferredcites →https://doi.org/10.1111/j.1467-9450.2010.00837.xopenalex-snapshot

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S33138 (N-[4-[2-[(3 aS,9 bR)-8-cyano-1,3 a,4,9 b-tetrahydro[1] benzopyrano[3,4-c]pyrrol-2(3 H)-yl)-ethyl]phenyl-acetamide), a Preferential Dopamine D3 versus D2 Receptor Antagonist and Potential Antipsychotic Agent: III. Actions in Models of Therapeutic Activity and Induction of Side Effects

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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Beyond substance use disorders

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Current drug treatments targeting dopamine D3 receptor

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Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4

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Effects of various cannabinoid ligands on choice behaviour in a rat model of gambling

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Effects of D3-preferring agonist PD 128907 on compulsive behaviour and decision making as assessed by the 5C-CPT

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