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Oxidative stress and expression of insulin signaling proteins in the brain of diabetic rats: Role of Nigella sativa oil and antidiabetic drugs

https://doi.org/10.1371/journal.pone.0172429
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases
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Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug
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Effects of the hydro-alcoholic extract of Nigella sativa on scopolamine-induced spatial memory impairment in rats and its possible mechanism
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“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
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Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity
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miR-29c regulates BACE1 protein expression
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Neuroprotective effects of thymoquinone against transient forebrain ischemia in the rat hippocampus
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High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex
inferredcites →https://doi.org/10.1016/j.jep.2004.04.030openalex-snapshot
The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat
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A study on neuroinflammation and NMDA receptor function in STZ (ICV) induced memory impaired rats
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Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: A model for type 2 diabetes and pharmacological screening
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Glutathione S-Transferases
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MicroRNAs
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Vascular risk factors for Alzheimer’s disease:
inferredcites →https://doi.org/10.1016/s1262-3636(03)72793-1openalex-snapshot
Metformin inhibition of glycation processes
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Alzheimer's Disease
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Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
inferredcites →https://doi.org/10.1073/pnas.0710263105openalex-snapshot
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/β-secretase expression
inferredcites →https://doi.org/10.1073/pnas.0807991106openalex-snapshot
Antidiabetic drug metformin (Glucophage R ) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
inferredcites →https://doi.org/10.1073/pnas.0912793107openalex-snapshot
Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling
inferredcites →https://doi.org/10.1074/jbc.m210689200openalex-snapshot
Suppressor of Cytokine Signaling-3 (SOCS-3), a Potential Mediator of Interleukin-6-dependent Insulin Resistance in Hepatocytes
inferredcites →https://doi.org/10.1080/02646830500382037openalex-snapshot
Clinical aspects of inflammation in Alzheimer's disease
inferredcites →https://doi.org/10.1093/clinchem/27.10.1642openalex-snapshot
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Metabolic Processes in Alzheimer's Disease: Adenine Nucleotide Content and Production of 14CO2 from [U‐14C]Glucose In Vitro in Human Neocortex
inferredcites →https://doi.org/10.1111/j.1582-4934.2011.01318.xopenalex-snapshot
Possible implications of insulin resistance and glucose metabolism in Alzheimer’s disease pathogenesis
inferredcites →https://doi.org/10.1152/ajpendo.90437.2008openalex-snapshot
Phosphorylation of IRS proteins, insulin action, and insulin resistance
inferredcites →https://doi.org/10.1155/2016/2492107openalex-snapshot
Nigella sativa Relieves the Altered Insulin Receptor Signaling in Streptozotocin‐Induced Diabetic Rats Fed with a High‐Fat Diet
inferredcites →https://doi.org/10.1155/2016/5264064openalex-snapshot
Changes in Oxidative Stress and Antioxidant Enzyme Activities in Streptozotocin‐Induced Diabetes Mellitus in Rats: Role of Alhagi maurorum Extracts
inferredcites →https://doi.org/10.1159/000136485openalex-snapshot
Bromobenzene-Induced Liver Necrosis. Protective Role of Glutathione and Evidence for 3,4-Bromobenzene Oxide as the Hepatotoxic Metabolite
inferredcites →https://doi.org/10.1159/000337428openalex-snapshot
Risk of Alzheimer’s Disease in Relation to Diabetes: A Population-Based Cohort Study
inferredcites →https://doi.org/10.1172/jci59903openalex-snapshot
Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
inferredcites →https://doi.org/10.1186/1475-2840-13-15openalex-snapshot
Possible effects of glimepiride beyond glycemic control in patients with type 2 diabetes: a preliminary report
inferredcites →https://doi.org/10.1186/1742-2094-11-115openalex-snapshot
Glimepiride reduces CD14 expression and cytokine secretion from macrophages
inferredcites →https://doi.org/10.1210/jc.87.1.226openalex-snapshot
Fatty Acid-Induced Insulin Resistance: Decreased Muscle PI3K Activation But Unchanged Akt Phosphorylation
inferredcites →https://doi.org/10.1254/jphs.crj05006xopenalex-snapshot
New Twist on Neuronal Insulin Receptor Signaling in Health, Disease, and Therapeutics
inferredcites →https://doi.org/10.1261/rna.5980303openalex-snapshot
A microRNA array reveals extensive regulation of microRNAs during brain development
inferredcites →https://doi.org/10.2174/18715273113126660153openalex-snapshot
Alzheimer Disease and Type 2 Diabetes Mellitus: The Link to Tyrosine Hydroxylase and Probable Nutritional Strategies
inferredcites →https://doi.org/10.3233/jad-2010-091603openalex-snapshot
MiR-107 is Reduced in Alzheimer's Disease Brain Neocortex: Validation Study
inferredcites →https://doi.org/10.4049/jimmunol.181.6.3877openalex-snapshot
Cytokine-Mediated Inhibition of Fibrillar Amyloid-β Peptide Degradation by Human Mononuclear Phagocytes
inferredcites →https://doi.org/10.4161/cc.6.8.4135openalex-snapshot
Inflammation in Obesity is a Common Link Between Defects in Fatty Acid Metabolism and Insulin Resistance

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Molecular alteration of the proteasome contributes to AD-like pathology in the brain of HFD-STZ diabetic rats
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Associations of the triglyceride-glucose index and its obesity-related derivative with all-cause mortality, cardiovascular events, and long-term survival and functioning in older adults
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Therapeutic potentials of Nigella sativa preparations and its constituents in the management of diabetes and its complications in experimental animals and patients with diabetes mellitus: A systematic review
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Exendin-4 protects against high glucose-induced mitochondrial dysfunction and oxidative stress in SH-SY5Y neuroblastoma cells through GLP-1 receptor/Epac/Akt signaling
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Sustained feeding of a diet high in fat resulted in a decline in the liver's insulin-degrading enzyme levels in association with the induction of oxidative and endoplasmic reticulum stress in adult male rats: Evaluation of 4-phenylbutyric acid
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Altered static and dynamic functional network connectivity between subcortical nuclei and cortical regions of the default mode network in type 2 diabetes mellitus
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Oxidative Stress and MicroRNAs in Endothelial Cells under Metabolic Disorders
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