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Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation

https://doi.org/10.1371/journal.pone.0188381
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hep.20957openalex-snapshot
Alcohol and Oxidative Liver Injury
inferredcites →https://doi.org/10.1002/hep.22470openalex-snapshot
The critical role of toll‐like receptor (TLR) 4 in alcoholic liver disease is independent of the common TLR adapter MyD88†
inferredcites →https://doi.org/10.1007/s00204-009-0432-0openalex-snapshot
Role of oxidative stress in alcohol-induced liver injury
inferredcites →https://doi.org/10.1007/s12272-011-0905-6openalex-snapshot
Protective constituents against sepsis in mice from the root barks of Ulmus davidiana var. japonica
inferredcites →https://doi.org/10.1016/j.biochi.2007.09.019openalex-snapshot
Ethanol consumption impairs regulation of fatty acid metabolism by decreasing the activity of AMP-activated protein kinase in rat liver
inferredcites →https://doi.org/10.1016/j.cmet.2011.03.009openalex-snapshot
AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice
inferredcites →https://doi.org/10.1016/j.fct.2012.02.008openalex-snapshot
Quercetin prevents ethanol-induced dyslipidemia and mitochondrial oxidative damage
inferredcites →https://doi.org/10.1016/j.fct.2013.10.011openalex-snapshot
Hepatoprotective effect of mulberry water extracts on ethanol-induced liver injury via anti-inflammation and inhibition of lipogenesis in C57BL/6J mice
inferredcites →https://doi.org/10.1016/j.fitote.2006.11.013openalex-snapshot
Sesquiterpenes from Ulmus davidiana var. japonica with the inhibitory effects on lipopolysaccharide-induced nitric oxide production
inferredcites →https://doi.org/10.1016/j.foodchem.2007.10.081openalex-snapshot
Free radical scavenging and total phenolic contents from methanolic extracts of Ulmus davidiana
inferredcites →https://doi.org/10.1016/j.foodchem.2009.09.085openalex-snapshot
HPLC analysis and antioxidant activity of Ulmus davidiana and some flavonoids
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2012.06.029openalex-snapshot
Cytochrome P4502E1, oxidative stress, JNK, and autophagy in acute alcohol-induced fatty liver
inferredcites →https://doi.org/10.1016/j.jff.2016.04.024openalex-snapshot
Prunus mume Sieb. et Zucc. fruit ameliorates alcoholic liver injury in mice by inhibiting apoptosis and inflammation through oxidative stress
inferredcites →https://doi.org/10.1016/j.mam.2004.02.019openalex-snapshot
Oxidative stress and antioxidant defenses in ethanol-induced cell injury
inferredcites →https://doi.org/10.1016/s0006-291x(02)00586-7openalex-snapshot
Dilinoleoylphosphatidylcholine decreases LPS-induced TNF-α generation in Kupffer cells of ethanol-fed rats: respective roles of MAPKs and NF-κB
inferredcites →https://doi.org/10.1016/s0741-8329(03)00100-9openalex-snapshot
Iron-dependent activation of NF-κB in Kupffer cells: a priming mechanism for alcoholic liver disease
inferredcites →https://doi.org/10.1021/jf904407xopenalex-snapshot
Effect of Anthocyanin-Rich Extract from Black Rice ( Oryza sativa L. Japonica ) on Chronically Alcohol-Induced Liver Damage in Rats
inferredcites →https://doi.org/10.1039/c1fo10170fopenalex-snapshot
Dietary agents in the prevention of alcohol-induced hepatotoxicty: preclinical observations
inferredcites →https://doi.org/10.1053/gast.2003.50089openalex-snapshot
Acetaldehyde impairs mitochondrial glutathione transport in HepG2 cells through endoplasmic reticulum stress
inferredcites →https://doi.org/10.1053/j.gastro.2009.06.045openalex-snapshot
c-Jun N-terminal Kinase-1 From Hematopoietic Cells Mediates Progression From Hepatic Steatosis to Steatohepatitis and Fibrosis in Mice
inferredcites →https://doi.org/10.1074/jbc.274.50.35832openalex-snapshot
Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes
inferredcites →https://doi.org/10.1074/jbc.m202411200openalex-snapshot
Ethanol Induces Fatty Acid Synthesis Pathways by Activation of Sterol Regulatory Element-binding Protein (SREBP)
inferredcites →https://doi.org/10.1074/jbc.m802187200openalex-snapshot
SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase
inferredcites →https://doi.org/10.1089/jmf.2009.1207openalex-snapshot
Isolation and Anti-Inflammatory Activity of Bakuchiol from Ulmus davidiana var. japonica
inferredcites →https://doi.org/10.1093/ajcn/70.5.928openalex-snapshot
De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption
inferredcites →https://doi.org/10.1111/acer.13078openalex-snapshot
A Mechanistic Review of Cell Death in Alcohol‐Induced Liver Injury
inferredcites →https://doi.org/10.1111/acer.13172openalex-snapshot
Dietary Fisetin Supplementation Protects Against Alcohol‐Induced Liver Injury in Mice
inferredcites →https://doi.org/10.1111/j.1478-3231.2007.01483.xopenalex-snapshot
Current concepts in the pathogenesis of nonalcoholic fatty liver disease
inferredcites →https://doi.org/10.1124/dmd.31.12.1499openalex-snapshot
ACETAMINOPHEN-INDUCED HEPATOTOXICITY
inferredcites →https://doi.org/10.1152/ajpendo.00011.2008openalex-snapshot
Alcohol and lipid metabolism
inferredcites →https://doi.org/10.1152/ajpgi.00098.2006openalex-snapshot
Chronic ethanol-mediated decrease in cAMP primes macrophages to enhanced LPS-inducible NF-κB activity and TNF expression: relevance to alcoholic liver disease
inferredcites →https://doi.org/10.1152/ajpgi.00575.2007openalex-snapshot
Involvement of mammalian sirtuin 1 in the action of ethanol in the liver
inferredcites →https://doi.org/10.1172/jci105323openalex-snapshot
Role of dietary, adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver.
inferredcites →https://doi.org/10.1172/jci105448openalex-snapshot
Effects of prolonged ethanol intake in man: role of dietary adipose, and endogenously synthesized fatty acids in the pathogenesis of the alcoholic fatty liver.
inferredcites →https://doi.org/10.1172/jci17305openalex-snapshot
Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
inferredcites →https://doi.org/10.1194/jlr.r800079-jlr200openalex-snapshot
Fatty acid metabolism: target for metabolic syndrome
inferredcites →https://doi.org/10.1254/jphs.08044fpopenalex-snapshot
Reactive Oxygen Species Mediate Oridonin-Induced HepG2 Apoptosis Through p53, MAPK, and Mitochondrial Signaling Pathways
inferredcites →https://doi.org/10.1371/journal.pone.0020635openalex-snapshot
Catechin Suppresses an Array of Signalling Molecules and Modulates Alcohol-Induced Endotoxin Mediated Liver Injury in a Rat Model
inferredcites →https://doi.org/10.3109/10715762.2013.837577openalex-snapshot
Involvement of free radicals and oxidative stress in NAFLD/NASH
inferredcites →https://doi.org/10.3168/jds.2016-11219openalex-snapshot
β-Hydroxybutyrate induces bovine hepatocyte apoptosis via an ROS-p38 signaling pathway
inferredcites →https://doi.org/10.3390/v5020439openalex-snapshot
HCV and Oxidative Stress in the Liver
inferredcites →https://doi.org/10.3978/j.issn.2304-3881.2014.12.06openalex-snapshot
Sirtuin 1 signaling and alcoholic fatty liver disease.
inferredcites →https://doi.org/10.4062/biomolther.2008.16.1.009openalex-snapshot
Antioxidant and Anti-Nociceptive Activities of Ulmus davidiana var. japonica
inferredcites →https://doi.org/10.4062/biomolther.2010.18.3.321openalex-snapshot
Anti-Inflammatory Activity of Constituents Isolated from Ulmus davidiana var. japonica

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.3983804openalex-extracted
inferred← citeshttps://doi.org/10.1007/s12257-018-0391-5openalex-snapshot
Antioxidant Peptide Purified from Enzymatic Hydrolysates of Isochrysis Zhanjiangensis and Its Protective Effect against Ethanol Induced Oxidative Stress of HepG2 Cells
inferred← citeshttps://doi.org/10.1007/s13258-019-00883-xopenalex-snapshot
Oral administration of Ulmus davidiana extract suppresses interleukin-1β expression in LPS-induced immune responses and lung injury
inferred← citeshttps://doi.org/10.1016/j.abb.2021.108969openalex-snapshot
Bakuchiol, main component of root bark of Ulmus davidiana var. japonica, inhibits TGF-β-induced in vitro EMT and in vivo metastasis
inferred← citeshttps://doi.org/10.1016/j.bbrep.2018.10.003openalex-snapshot
Assessment of hepatoprotective potential of Radix Fici Hirtae on alcohol-induced liver injury in Kunming mice
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103145openalex-snapshot
Chemical constituents of the root bark of Ulmus davidiana var. japonica and their potential biological activities
inferred← citeshttps://doi.org/10.1016/j.fitote.2024.106188openalex-snapshot
Catechin and flavonoid glycosides from the Ulmus genus: Exploring their nutritional pharmacology and therapeutic potential in osteoporosis and inflammatory conditions
inferred← citeshttps://doi.org/10.1016/j.jff.2019.04.001openalex-snapshot
Cranberry (Vaccinium macrocarpon) peel polyphenol-rich extract attenuates rat liver mitochondria impairments in alcoholic steatohepatitis in vivo and after oxidative treatment in vitro
inferred← citeshttps://doi.org/10.1016/j.nanoen.2022.107091openalex-snapshot
Biocompatible and mechanically-reinforced tribopositive nanofiber mat for wearable and antifungal human kinetic-energy harvester based on wood-derived natural product
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.104501openalex-snapshot
Natural products, extracts and formulations comprehensive therapy for the improvement of motor function in alcoholic liver disease
inferred← citeshttps://doi.org/10.1039/c9fo00153kopenalex-snapshot
Mangiferin improves hepatic damage-associated molecular patterns, lipid metabolic disorder and mitochondrial dysfunction in alcohol hepatitis rats
inferred← citeshttps://doi.org/10.1039/d0fo02831bopenalex-snapshot
Selenite supplementation modulates the hepatic metabolic sensors AMPK and SIRT1 in binge drinking exposed adolescent rats by avoiding oxidative stress
inferred← citeshttps://doi.org/10.1080/08923973.2019.1613427openalex-snapshot
Paeonol alleviates CCl4-induced liver fibrosis through suppression of hepatic stellate cells activation via inhibiting the TGF-β/Smad3 signaling
inferred← citeshttps://doi.org/10.1080/21580103.2024.2354267openalex-snapshot
Chemotaxonomic significance of catechin 7-O-beta-D-apiofuranoside in Ulmus species native to Asia
inferred← citeshttps://doi.org/10.1111/jre.13278openalex-snapshot
Periodontal pathogen Fusobacterium nucleatum infection accelerates hepatic steatosis in high‐fat diet‐fed ApoE knockout mice by inhibiting Nrf2/Keap1 signaling
inferred← citeshttps://doi.org/10.1155/2019/8506195openalex-snapshot
The Beneficial Roles of SIRT1 in Drug-Induced Liver Injury
inferred← citeshttps://doi.org/10.1155/2019/9097276openalex-snapshot
Probiotics for Alleviating Alcoholic Liver Injury
inferred← citeshttps://doi.org/10.1155/2021/2870969openalex-snapshot
Potential Effects of Dietary Isoflavones on Drug-Induced Liver Injury
inferred← citeshttps://doi.org/10.1177/09603271211052987openalex-snapshot
The role of ferroptosis in organ toxicity
inferred← citeshttps://doi.org/10.1186/s10020-021-00427-8openalex-snapshot
Abnormal lipid droplets accumulation induced cognitive deficits in obstructive sleep apnea syndrome mice via JNK/SREBP/ACC pathway but not through PDP1/PDC pathway
inferred← citeshttps://doi.org/10.2478/afpuc-2022-0014openalex-snapshot
Anthocyanin-Rich Extract of Red Cabbage Attenuates Advanced Alcohol Hepatotoxicity in Rats in Association with Mitochondrial Activity Modulation
inferred← citeshttps://doi.org/10.3390/antiox9100981openalex-snapshot
Potential Anti-Skin Aging Effect of (-)-Catechin Isolated from the Root Bark of Ulmus davidiana var. japonica in Tumor Necrosis Factor-α-Stimulated Normal Human Dermal Fibroblasts
inferred← citeshttps://doi.org/10.3390/biomedicines12061138openalex-snapshot
The Role of Natural Products in Diabetic Retinopathy
inferred← citeshttps://doi.org/10.3390/molecules27041419openalex-snapshot
Regulation of Cytokines and Dihydrotestosterone Production in Human Hair Follicle Papilla Cells by Supercritical Extraction-Residues Extract of Ulmus davidiana
inferred← citeshttps://doi.org/10.3390/nu11050963openalex-snapshot
Hepatoprotective Potential of Partially Hydrolyzed Guar Gum against Acute Alcohol-Induced Liver Injury in Vitro and Vivo
inferred← citeshttps://doi.org/10.3746/jkfn.2025.54.6.506openalex-snapshot
Quality Characteristics and Antioxidant Activity of Yanggaeng with Elm (Ulmus davidiana var. japonica Nakai) Root Bark Powder
inferred← citeshttps://doi.org/10.3892/ijo.2018.4379openalex-snapshot
Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway
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