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Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/(sici)1526-968x(200002)26:2<99::aid-gene1>3.0.co;2-bopenalex-snapshot
Cre recombinase: The universal reagent for genome tailoring
inferredcites →https://doi.org/10.1002/1526-968x(200011/12)28:3/4<106::aid-gene30>3.0.co;2-topenalex-snapshot
Widespread recombinase expression using FLPeR (Flipper) mice
inferredcites →https://doi.org/10.1002/dvdy.20948openalex-snapshot
Inducible Cre recombinase activity in mouse cerebellar granule cell precursors and inner ear hair cells
inferredcites →https://doi.org/10.1002/dvg.20335openalex-snapshot
A global double‐fluorescent Cre reporter mouse
inferredcites →https://doi.org/10.1002/dvg.20641openalex-snapshot
An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinase
inferredcites →https://doi.org/10.1002/gene.10153openalex-snapshot
ER‐based double icre fusion protein allows partial recombination in forebrain
inferredcites →https://doi.org/10.1002/gene.10226openalex-snapshot
Highly efficient transgene‐independent recombination directed by a maternally derived SOX2CRE transgene
inferredcites →https://doi.org/10.1006/bbrc.1997.7124openalex-snapshot
Regulation of Cre Recombinase Activity by Mutated Estrogen Receptor Ligand-Binding Domains
inferredcites →https://doi.org/10.1006/meth.2001.1159openalex-snapshot
Site- and Time-Specific Gene Targeting in the Mouse
inferredcites →https://doi.org/10.1007/s10162-012-0324-5openalex-snapshot
Conditional Gene Expression in the Mouse Inner Ear Using Cre-loxP
inferredcites →https://doi.org/10.1007/s11248-017-0018-1openalex-snapshot
Spontaneous recombinase activity of Cre–ERT2 in vivo
inferredcites →https://doi.org/10.1007/s12033-011-9381-yopenalex-snapshot
Improved FLP Recombinase, FLPe, Efficiently Removes Marker Gene from Transgene Locus Developed by Cre–lox Mediated Site-Specific Gene Integration in Rice
inferredcites →https://doi.org/10.1016/0092-8674(89)90033-0openalex-snapshot
The FLP recombinase of yeast catalyzes site-specific recombination in the drosophila genome
inferredcites →https://doi.org/10.1016/j.bbagrm.2011.07.009openalex-snapshot
The role of FACT in making and breaking nucleosomes
inferredcites →https://doi.org/10.1016/j.brainres.2006.01.040openalex-snapshot
Conditional and inducible gene recombineering in the mouse inner ear
inferredcites →https://doi.org/10.1016/j.celrep.2013.06.013openalex-snapshot
Facilitates Chromatin Transcription Complex Is an “Accelerator” of Tumor Transformation and Potential Marker and Target of Aggressive Cancers
inferredcites →https://doi.org/10.1016/j.jim.2014.05.009openalex-snapshot
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
inferredcites →https://doi.org/10.1016/s0039-128x(96)00086-4openalex-snapshot
Androgenic up-regulation of androgen receptor cDNA expression in androgen-independent prostate cancer cells
inferredcites →https://doi.org/10.1038/nature10163openalex-snapshot
A conditional knockout resource for the genome-wide study of mouse gene function
inferredcites →https://doi.org/10.1038/nbt1001-929openalex-snapshot
Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase
inferredcites →https://doi.org/10.1038/ncomms2186openalex-snapshot
Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource
inferredcites →https://doi.org/10.1073/pnas.0610155104openalex-snapshot
Controlled expression of transgenes introduced by in vivo electroporation
inferredcites →https://doi.org/10.1073/pnas.161269798openalex-snapshot
Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells
inferredcites →https://doi.org/10.1073/pnas.93.19.10309openalex-snapshot
Use of genetic suppressor elements to dissect distinct biological effects of separate p53 domains.
inferredcites →https://doi.org/10.1073/pnas.93.20.10887openalex-snapshot
Ligand-activated site-specific recombination in mice.
inferredcites →https://doi.org/10.1093/nar/24.4.543openalex-snapshot
Inducible Site-Directed Recombination in Mouse Embryonic Stem Cells
inferredcites →https://doi.org/10.1093/nar/27.22.4324openalex-snapshot
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ERT and Cre-ERT2 recombinases
inferredcites →https://doi.org/10.1101/gad.1848209openalex-snapshot
Dicer1 functions as a haploinsufficient tumor suppressor
inferredcites →https://doi.org/10.1126/scitranslmed.aab1803openalex-snapshot
Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma
inferredcites →https://doi.org/10.1128/mcb.23.15.5301-5307.2003openalex-snapshot
The High-Mobility-Group Box Protein SSRP1/T160 Is Essential for Cell Viability in Day 3.5 Mouse Embryos
inferredcites →https://doi.org/10.1172/jci10458openalex-snapshot
Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase– and cathepsin-dependent emphysema
inferredcites →https://doi.org/10.1371/journal.pone.0046076openalex-snapshot
SPC-Cre-ERT2 Transgenic Mouse for Temporal Gene Deletion in Alveolar Epithelial Cells
inferredcites →https://doi.org/10.1631/jzus.b1200042openalex-snapshot
Conditional gene manipulation: Cre-ating a new biological era
inferredcites →https://doi.org/10.18632/oncotarget.2701openalex-snapshot
Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer
inferredcites →https://doi.org/10.18632/oncotarget.340openalex-snapshot
Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells
inferredcites →https://doi.org/10.2147/bctt.s126390openalex-snapshot
Prognostic value of histone chaperone FACT subunits expression in breast cancer
inferredcites →https://doi.org/10.4161/cc.25452openalex-snapshot
Complex mutual regulation of facilitates chromatin transcription (FACT) subunits on both mRNA and protein levels in human cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.3388354openalex-extracted
Prevention of Chromatin Destabilization by FACT Is Crucial for Malignant Transformation
inferred← citeshttps://doi.org/10.1002/cpns.88openalex-snapshot
Back and to the Future: From Neurotoxin‐Induced to Human Parkinson's Disease Models
inferred← citeshttps://doi.org/10.1007/978-1-0716-1008-4_13openalex-snapshot
Gene Inactivation in Adult Long-Term Hematopoietic Stem Cells Using Inducible Mouse Models
inferred← citeshttps://doi.org/10.1007/978-3-031-37978-9_53openalex-snapshot
Assessment of Embryonic and Postembryonic Vitality of F3 Progenies Obtained Under Unfavorable Stress Conditions of Breeds and Systems
inferred← citeshttps://doi.org/10.1016/j.bbagrm.2018.07.008openalex-snapshot
Structure and function of the histone chaperone FACT – Resolving FACTual issues
inferred← citeshttps://doi.org/10.1016/j.exphem.2023.08.005openalex-snapshot
Complementary and countervailing actions of Jak2 and Ikk2 in hematopoiesis in mice
inferred← citeshttps://doi.org/10.1016/j.genrep.2023.101825openalex-snapshot
Utilizing Cre-lox-based mouse genetic tools in neuroscience research
inferred← citeshttps://doi.org/10.1016/j.isci.2020.101177openalex-snapshot
Prevention of Chromatin Destabilization by FACT Is Crucial for Malignant Transformation
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2019.12.013openalex-snapshot
A neuroscientist’s guide to transgenic mice and other genetic tools
inferred← citeshttps://doi.org/10.1016/j.taap.2023.116787openalex-snapshot
Arsenic up-regulates PD-L1 and enhances lung tumorigenesis through activation of STAT3 in alveolar epithelial type 2 cells
inferred← citeshttps://doi.org/10.1016/j.ymeth.2021.04.001openalex-snapshot
Droplet digital PCR or quantitative PCR for in-depth genomic and functional validation of genetically altered rodents
inferred← citeshttps://doi.org/10.1017/s0952523821000043openalex-snapshot
Myelin regulatory factor deficiency is associated with the retinal photoreceptor defects in mice
inferred← citeshttps://doi.org/10.1038/s41388-020-1346-9openalex-snapshot
Histone chaperone FACT is essential to overcome replication stress in mammalian cells
inferred← citeshttps://doi.org/10.1038/s44161-022-00162-1openalex-snapshot
Generation and comparative analysis of an Itga8-CreERT2 mouse with preferential activity in vascular smooth muscle cells
inferred← citeshttps://doi.org/10.1093/hmg/ddae080openalex-snapshot
Lymphatic endothelial cell-specific NRAS p.Q61R mutant embryos show abnormal lymphatic vessel morphogenesis
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000002536openalex-snapshot
Prdm12 modulates pain-related behavior by remodeling gene expression in mature nociceptors
inferred← citeshttps://doi.org/10.1101/2021.06.21.449309openalex-snapshot
FACT-mediated maintenance of chromatin integrity during transcription is essential for mammalian stem cell viability
inferred← citeshttps://doi.org/10.1101/2022.02.03.479061openalex-snapshot
An Inducible Cre Mouse with Preferential Activity in Vascular Smooth Muscle Evades a Previously Lethal Intestinal Phenotype
inferred← citeshttps://doi.org/10.1111/pcmr.12843openalex-snapshot
GNAQQ209L expression initiated in multipotent neural crest cells drives aggressive melanoma of the central nervous system
inferred← citeshttps://doi.org/10.1113/jp284059openalex-snapshot
Cholinergic collaterals arising from noradrenergic sympathetic neurons in mice
inferred← citeshttps://doi.org/10.1186/s44477-025-00010-zopenalex-snapshot
Global C3 lowering in adulthood protects against hippocampal dysfunction and cognitive impairment in aged mice
inferred← citeshttps://doi.org/10.1261/rna.077958.120openalex-snapshot
A method for colocalizing lineage tracing reporter and RNAscope signals on skeletal tissue section
inferred← citeshttps://doi.org/10.1523/eneuro.0470-19.2020openalex-snapshot
Poor Concordance of Floxed Sequence Recombination in Single Neural Stem Cells: Implications for Cell Autonomous Studies
inferred← citeshttps://doi.org/10.15252/embr.202153684openalex-snapshot
FACT maintains nucleosomes during transcription and stem cell viability in adult mice
inferred← citeshttps://doi.org/10.20517/2394-4722.2019.31openalex-snapshot
Histone chaperone FACT and curaxins: effects on genome structure and function
inferred← citeshttps://doi.org/10.3390/ijms231912008openalex-snapshot
Oocyte-Specific Knockout of Histone Lysine Demethylase KDM2a Compromises Fertility by Blocking the Development of Follicles and Oocytes
inferred← citeshttps://doi.org/10.3390/ijms232214077openalex-snapshot
Limitations of Tamoxifen Application for In Vivo Genome Editing Using Cre/ERT2 System
inferred← citeshttps://doi.org/10.64898/2026.02.26.708215openalex-snapshot
FACT depletion results in a temporal cascade of chromatin disruption preceding transcriptional collapse in stem cells
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