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Novel models for assessing blood–brain barrier drug permeation
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ar.b.20087openalex-snapshot
Development of the blood‐brain barrier: A historical point of view
inferredcites →https://doi.org/10.1002/bdrc.20212openalex-snapshot
The developing zebrafish (Danio rerio): A vertebrate model for high‐throughput screening of chemical libraries
inferredcites →https://doi.org/10.1002/bdrc.20216openalex-snapshot
A high‐content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling
inferredcites →https://doi.org/10.1002/dneu.20910openalex-snapshot
Behavioral screening for neuroactive drugs in zebrafish
inferredcites →https://doi.org/10.1002/glia.21147openalex-snapshot
Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila
inferredcites →https://doi.org/10.1002/mds.23546openalex-snapshot
New animal models of Parkinson's disease
inferredcites →https://doi.org/10.1002/wsbm.147openalex-snapshot
Drug repurposing and adverse event prediction using high‐throughput literature analysis
inferredcites →https://doi.org/10.1007/164_2020_370openalex-snapshot
In Vitro Models of the Blood-Brain Barrier
inferredcites →https://doi.org/10.1007/978-1-60761-938-3_17openalex-snapshot
Novel Models for Studying the Blood-Brain and Blood-Eye Barriers in Drosophila
inferredcites →https://doi.org/10.1007/978-1-60761-938-3_5openalex-snapshot
The Blood-Retinal Barrier: Structure and Functional Significance
inferredcites →https://doi.org/10.1007/s10571-004-1374-yopenalex-snapshot
Dynamics of CNS Barriers: Evolution, Differentiation, and Modulation
inferredcites →https://doi.org/10.1016/b978-0-12-381320-6.00021-7openalex-snapshot
Chemical Screening in Zebrafish for Novel Biological and Therapeutic Discovery
inferredcites →https://doi.org/10.1016/j.brainresbull.2007.10.043openalex-snapshot
Functional and developmental analysis of the blood–brain barrier in zebrafish
inferredcites →https://doi.org/10.1016/j.cell.2005.07.029openalex-snapshot
moody Encodes Two GPCRs that Regulate Cocaine Behaviors and Blood-Brain Barrier Permeability in Drosophila
inferredcites →https://doi.org/10.1016/j.drudis.2006.10.013openalex-snapshot
Blood–brain barrier delivery
inferredcites →https://doi.org/10.1016/j.drudis.2010.12.004openalex-snapshot
Drug delivery to the posterior segment of the eye
inferredcites →https://doi.org/10.1016/j.drudis.2011.04.004openalex-snapshot
Models for predicting blood–brain barrier permeation
inferredcites →https://doi.org/10.1016/j.drudis.2011.10.006openalex-snapshot
Case study: adapting in vitro blood–brain barrier models for use in early-stage drug discovery
inferredcites →https://doi.org/10.1016/j.healthpol.2010.12.002openalex-snapshot
The cost of drug development: A systematic review
inferredcites →https://doi.org/10.1016/j.nbd.2009.07.030openalex-snapshot
Structure and function of the blood–brain barrier
inferredcites →https://doi.org/10.1016/j.nbd.2011.05.016openalex-snapshot
Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models
inferredcites →https://doi.org/10.1016/j.neuint.2008.12.002openalex-snapshot
A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
inferredcites →https://doi.org/10.1016/j.pneurobio.2010.01.001openalex-snapshot
The functional organisation of glia in the adult brain of Drosophila and other insects
inferredcites →https://doi.org/10.1016/s0167-6296(02)00126-1openalex-snapshot
The price of innovation: new estimates of drug development costs
inferredcites →https://doi.org/10.1016/s1359-6446(03)02827-7openalex-snapshot
In silico prediction of blood–brain barrier permeation
inferredcites →https://doi.org/10.1017/s1462399411001918openalex-snapshot
Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases
inferredcites →https://doi.org/10.1021/cb700009mopenalex-snapshot
Invertebrate Animal Models of Diseases as Screening Tools in Drug Discovery
inferredcites →https://doi.org/10.1021/jm040114bopenalex-snapshot
Chemical Modification of Paclitaxel (Taxol) Reduces P-Glycoprotein Interactions and Increases Permeation across the Blood−Brain Barrier in Vitro and in Situ
inferredcites →https://doi.org/10.1038/clpt.2010.354openalex-snapshot
Transporter-Mediated Drug Uptake and Efflux: Important Determinants of Adverse Drug Reactions
inferredcites →https://doi.org/10.1038/nrd1032openalex-snapshot
ADMET in silico modelling: towards prediction paradise?
inferredcites →https://doi.org/10.1038/nrd2368openalex-snapshot
Modelling of the blood–brain barrier in drug discovery and development
inferredcites →https://doi.org/10.1073/pnas.1102116108openalex-snapshot
Drug screening in a zebrafish model of Duchenne muscular dystrophy
inferredcites →https://doi.org/10.1083/jcb.40.3.648openalex-snapshot
JUNCTIONS BETWEEN INTIMATELY APPOSED CELL MEMBRANES IN THE VERTEBRATE BRAIN
inferredcites →https://doi.org/10.1093/hmg/ddr312openalex-snapshot
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models
inferredcites →https://doi.org/10.1111/j.1471-4159.2010.06948.xopenalex-snapshot
Chronic exposure to nicotine and saquinavir decreases endothelial Notch‐4 expression and disrupts blood‐brain barrier integrity
inferredcites →https://doi.org/10.1111/j.1471-4159.2010.07054.xopenalex-snapshot
Nicotine and cotinine increases the brain penetration of saquinavir in rat
inferredcites →https://doi.org/10.1111/j.1476-5381.2010.00725.xopenalex-snapshot
High‐throughput screening and small animal models, where are we?
inferredcites →https://doi.org/10.1113/jphysiol.1990.sp018243openalex-snapshot
Electrical resistance across the blood‐brain barrier in anaesthetized rats: a developmental study.
inferredcites →https://doi.org/10.1124/mi.10.5.6openalex-snapshot
Regulation of ABC Transporters at the Blood-Brain Barrier: New Targets for CNS Therapy
inferredcites →https://doi.org/10.1124/pr.110.003293openalex-snapshot
Human Disease Models in Drosophila melanogaster and the Role of the Fly in Therapeutic Drug Discovery
inferredcites →https://doi.org/10.1146/annurev.ento.45.1.151openalex-snapshot
Blood Barriers of the Insect
inferredcites →https://doi.org/10.1146/annurev.neuro.30.051606.094345openalex-snapshot
Neuron-Glial Interactions in Blood-Brain Barrier Formation
inferredcites →https://doi.org/10.1152/physiol.00027.2004openalex-snapshot
The Molecular Physiology of Tight Junction Pores
inferredcites →https://doi.org/10.1158/1078-0432.ccr-10-1564openalex-snapshot
Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer
inferredcites →https://doi.org/10.1186/1471-213x-10-76openalex-snapshot
A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development
inferredcites →https://doi.org/10.1242/jeb.109.1.319openalex-snapshot
Localization of the Blood-Brain Barrier of an Insect: Electrical Model and Analysis
inferredcites →https://doi.org/10.1371/journal.pone.0012386openalex-snapshot
Identification of Novel Inhibitors of Dietary Lipid Absorption Using Zebrafish
inferredcites →https://doi.org/10.1387/ijdb.103224slopenalex-snapshot
Current concepts of blood-brain barrier development
inferredcites →https://doi.org/10.1523/jneurosci.05-01-00117.1985openalex-snapshot
Embryonic development of glial cells and their junctions in the locust central nervous system
inferredcites →https://doi.org/10.1523/jneurosci.4367-07.2008openalex-snapshot
Organization and Function of the Blood–Brain Barrier in Drosophila
inferredcites →https://doi.org/10.1523/jneurosci.5564-08.2009openalex-snapshot
Evolutionary Conservation of Vertebrate Blood–Brain Barrier Chemoprotective Mechanisms inDrosophila
inferredcites →https://doi.org/10.18433/j39w2gopenalex-snapshot
New Perspectives on Innovative Drug Discovery: An Overview
inferredcites →https://doi.org/10.2174/138161211797440186openalex-snapshot
Breast Cancer Resistance Protein and P-Glycoprotein in Brain Cancer: Two Gatekeepers Team Up
inferredcites →https://doi.org/10.2174/138161211797440221openalex-snapshot
The ABC of the Blood-Brain Barrier - Regulation of Drug Efflux Pumps
inferredcites →https://doi.org/10.2174/138920006775541552openalex-snapshot
Preclinical Pharmacokinetics: An Approach Towards Safer and Efficacious Drugs
inferredcites →https://doi.org/10.2174/138920008786485182openalex-snapshot
Assays to Predict Drug Permeation Across the Blood-Brain Barrier, and Distribution to Brain
inferredcites →https://doi.org/10.2174/138920010792927325openalex-snapshot
Structure and Function of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)
inferredcites →https://doi.org/10.3109/10611860903548354openalex-snapshot
Biopharmaceutical drug targeting to the brain
inferredcites →https://doi.org/10.3109/10611861003639796openalex-snapshot
Brain-targeted delivery of Tempol-loaded nanoparticles for neurological disorders
inferredcites →https://doi.org/10.3109/1061186x.2011.589435openalex-snapshot
Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for brain cancers
inferredcites →https://doi.org/10.3390/ijms12042262openalex-snapshot
Multi-Step Usage of in Vivo Models During Rational Drug Design and Discovery
inferredcites →https://doi.org/10.4155/tde.10.76openalex-snapshot
Exploiting Nutrient Transporters at the blood–brain Barrier to Improve Brain Distribution of Small Molecules
inferredcites →https://doi.org/10.55782/ane-2011-1828openalex-snapshot
In vitro models of the blood-brain barrier
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4789967openalex-extracted
The Effect of N-(1-Benzylpiperidinyl-4)-4-Fluorobenzamide (Lmh-2) on the Amnesic Effect of Scopolamine in Zebrafish
inferred← citeshttps://doi.org/10.1002/0471141755.ph0715s62openalex-snapshot
Overview of Experimental Models of the Blood‐Brain Barrier in CNS Drug Discovery
inferred← citeshttps://doi.org/10.1002/9780470015902.a0022535openalex-snapshot
Screening for Anti‐cancer Drugs inDrosophila
inferred← citeshttps://doi.org/10.1002/9781118833322.ch7openalex-snapshot
Cell Culture Models for Drug Transport Studies
inferred← citeshttps://doi.org/10.1002/adhm.202303180openalex-snapshot
Microphysiological Blood‐Brain Barrier Systems for Disease Modeling and Drug Development
inferred← citeshttps://doi.org/10.1002/jcb.25307openalex-snapshot
A Molecular Docking and Dynamics Study to Screen Potent Anti-Staphylococcal Compounds Against Ceftaroline Resistant MRSA
inferred← citeshttps://doi.org/10.1002/prp2.50openalex-snapshot
Characterization of a novel brain barrier ex vivo insect‐based P‐glycoprotein screening model
inferred← citeshttps://doi.org/10.1007/7355_2013_27openalex-snapshot
In Vivo Approaches to Assessing the Blood–Brain Barrier
inferred← citeshttps://doi.org/10.1007/978-3-031-93871-9_14openalex-snapshot
Zebrafish as a Model to Investigate Nanoparticles
inferred← citeshttps://doi.org/10.1007/s11095-013-1156-7openalex-snapshot
Nanotechnology-Based Drug Delivery Systems for Targeting, Imaging and Diagnosis of Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.1007/s12013-016-0741-xopenalex-snapshot
Ethyl 4-(4-methylphenyl)-4-pentenoate from Vetiveria zizanioides Inhibits Dengue NS2B–NS3 Protease and Prevents Viral Assembly: A Computational Molecular Dynamics and Docking Study
inferred← citeshttps://doi.org/10.1016/b978-0-12-814001-7.00004-4openalex-snapshot
In vitro and in vivo models of BBB to evaluate brain targeting drug delivery
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.104681openalex-snapshot
Chalcone and its analogs: Therapeutic and diagnostic applications in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.bmcl.2021.127930openalex-snapshot
Development of an a priori computational approach for brain uptake of compounds in an insect model system
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2017.05.022openalex-snapshot
Zebrafish as a visual and dynamic model to study the transport of nanosized drug delivery systems across the biological barriers
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2022.113103openalex-snapshot
CRISPR/Cas9 targeting liposomes knocked down multidrug resistance proteins in brain endothelial cells as a model to predict potential pharmacoresistance
inferred← citeshttps://doi.org/10.1016/j.drudis.2012.11.008openalex-snapshot
The promiscuous binding of pharmaceutical drugs and their transporter-mediated uptake into cells: what we (need to) know and how we can do so
inferred← citeshttps://doi.org/10.1016/j.ejps.2018.04.026openalex-snapshot
Verapamil and riluzole cocktail liposomes overcome pharmacoresistance by inhibiting P-glycoprotein in brain endothelial and astrocyte cells: A potent approach to treat amyotrophic lateral sclerosis
inferred← citeshttps://doi.org/10.1016/j.ejps.2020.105539openalex-snapshot
Preparation, optimization and preliminary pharmacokinetic study of curcumin encapsulated turmeric oil microemulsion in zebra fish
inferred← citeshttps://doi.org/10.1016/j.jconrel.2018.01.024openalex-snapshot
In vitro models and systems for evaluating the dynamics of drug delivery to the healthy and diseased brain
inferred← citeshttps://doi.org/10.1016/j.jns.2022.120316openalex-snapshot
The brilliance of nanoscience over cancer therapy: Novel promising nanotechnology-based methods for eradicating glioblastoma
inferred← citeshttps://doi.org/10.1038/nm.3407openalex-snapshot
Development, maintenance and disruption of the blood-brain barrier
inferred← citeshttps://doi.org/10.1039/c5cp06090gopenalex-snapshot
On the atomic structure of cocaine in solution
inferred← citeshttps://doi.org/10.1039/c7cp01723eopenalex-snapshot
On the structure of prilocaine in aqueous and amphiphilic solutions
inferred← citeshttps://doi.org/10.1089/zeb.2016.1392openalex-snapshot
Zebrafish as a Screening Model for Testing the Permeability of Blood–Brain Barrier to Small Molecules
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A Comprehensive In Silico Study for the Identification of Therapeutic Target Against Peripheral Neuropathic Pain in humans
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Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it
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Identification of a Functional Homolog of the Mammalian CYP3A4 in Locusts
inferred← citeshttps://doi.org/10.1124/jpet.113.205476openalex-snapshot
The Grasshopper: A Novel Model for Assessing Vertebrate Brain Uptake
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Modeling blood–brain barrier–glioblastoma interactions: implications for chemoresistance and therapeutic targeting
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Delivery of Small Interfering RNA to Inhibit Vascular Endothelial Growth Factor in Zebrafish Using Natural Brain Endothelia Cell-Secreted Exosome Nanovesicles for the Treatment of Brain Cancer
inferred← citeshttps://doi.org/10.21007/etd.cghs.2014.0329openalex-snapshot
Genetic and Chemical Dissection of BloodBrain Barrier Development in Zebrafish
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Structural Modeling of Drosophila melanogaster Gut Cytochrome P450s and Docking Comparison of Fruit Fly Gut and Human Cytochrome P450s
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The blood-brain barrier: Structure, function and therapeutic approaches to cross it
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High-Throughput Screening for Identification of Blood-Brain Barrier Integrity Enhancers: A Drug Repurposing Opportunity to Rectify Vascular Amyloid Toxicity
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Bridging Size and Charge Effects of Mesoporous Silica Nanoparticles for Crossing the Blood–Brain Barrier
inferred← citeshttps://doi.org/10.3389/fnins.2014.00355openalex-snapshot
Dissecting gene expression at the blood-brain barrier
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Scopolamine-Induced Amnesia in Zebrafish: Behavioral Characterization and Pharmacological Reversal
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Towards Deep Neural Network Models for the Prediction of the Blood–Brain Barrier Permeability for Diverse Organic Compounds
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Formulation & Evaluation of PLGA Nanoparticles of Ropinirole HCl for Targeting Brain
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Molecular Determinants of blood–brain Barrier Permeation
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Synthèses et évaluations biologiques d’analogues de la combrétastatine A-4 et d’inhibiteurs de kinases DYRK
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