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Sperm selection by rheotaxis improves sperm quality and early embryo development

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/advs.201700531openalex-snapshot
Guidance and Self‐Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest
inferredcites →https://doi.org/10.1007/10815.1573-7330openalex-snapshot
Journal of Assisted Reproduction and Genetics
inferredcites →https://doi.org/10.1007/s10815-016-0696-2openalex-snapshot
The pellet swim-up is the best technique for sperm preparation during in vitro fertilization procedures
inferredcites →https://doi.org/10.1007/s10815-017-1024-1openalex-snapshot
Positive rheotaxis extended drop: a one-step procedure to select and recover sperm with mature chromatin for intracytoplasmic sperm injection
inferredcites →https://doi.org/10.1007/s10815-018-1163-zopenalex-snapshot
The effect of swim-up and gradient sperm preparation techniques on deoxyribonucleic acid (DNA) fragmentation in subfertile patients
inferredcites →https://doi.org/10.1016/0140-6736(92)92425-fopenalex-snapshot
Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte
inferredcites →https://doi.org/10.1016/j.fertnstert.2007.11.068openalex-snapshot
Semen preparation methods and sperm apoptosis: swim-up versus gradient-density centrifugation technique
inferredcites →https://doi.org/10.1016/j.fertnstert.2008.08.088openalex-snapshot
A new real-time morphology classification for human spermatozoa: a link for fertilization and improved embryo quality
inferredcites →https://doi.org/10.1016/j.fertnstert.2009.03.033openalex-snapshot
“Physiologic ICSI”: Hyaluronic acid (HA) favors selection of spermatozoa without DNA fragmentation and with normal nucleus, resulting in improvement of embryo quality
inferredcites →https://doi.org/10.1016/j.fertnstert.2015.10.023openalex-snapshot
Separation efficiency of a microfluidic sperm sorter to minimize sperm DNA damage
inferredcites →https://doi.org/10.1016/j.fertnstert.2018.06.039openalex-snapshot
International Committee for Monitoring Assisted Reproductive Technology: world report on assisted reproductive technology, 2011
inferredcites →https://doi.org/10.1016/j.rbmo.2010.07.004openalex-snapshot
New technique for mouse oocyte injection via a modified holding pipette
inferredcites →https://doi.org/10.1016/j.repbio.2015.03.003openalex-snapshot
The effect of sperm DNA fragmentation on the dynamics of the embryonic development in intracytoplasmatic sperm injection
inferredcites →https://doi.org/10.1016/j.theriogenology.2019.09.008openalex-snapshot
A modified holding pipette for mouse oocyte fertilization
inferredcites →https://doi.org/10.1016/j.wem.2013.09.006openalex-snapshot
Journal Of Clinical and Diagnostic Research
inferredcites →https://doi.org/10.1016/s1472-6483(10)60308-2openalex-snapshot
Blastocyst development after sperm selection at high magnification is associated with size and number of nuclear vacuoles
inferredcites →https://doi.org/10.1016/s1472-6483(10)60975-3openalex-snapshot
High-magnification ICSI overcomes paternal effect resistant to conventional ICSI
inferredcites →https://doi.org/10.1038/s41598-018-21335-8openalex-snapshot
Sperm selection by thermotaxis improves ICSI outcome in mice
inferredcites →https://doi.org/10.1038/s41598-020-65931-zopenalex-snapshot
Successful selection of mouse sperm with high viability and fertility using microfluidics chip cell sorter
inferredcites →https://doi.org/10.1038/srep23553openalex-snapshot
Human sperm rheotaxis: a passive physical process
inferredcites →https://doi.org/10.1046/j.1365-2605.2001.00309.xopenalex-snapshot
Membrane fluidity and lipid content of human spermatozoa selected by swim-up method
inferredcites →https://doi.org/10.1046/j.1365-2605.2001.0240s1025.xopenalex-snapshot
International Journal of Andrology
inferredcites →https://doi.org/10.1080/14647273.2018.1424354openalex-snapshot
Clinical outcomes of magnetic activated sperm sorting in infertile men candidate for ICSI
inferredcites →https://doi.org/10.1093/hropen/hoz038openalex-snapshot
ART in Europe, 2015: results generated from European registries by ESHRE†
inferredcites →https://doi.org/10.1093/humrep/13.suppl_1.87openalex-snapshot
Intracytoplasmic sperm injection experiments using the mouse as a model
inferredcites →https://doi.org/10.1093/humrep/deh280openalex-snapshot
The predictive value of sperm chromatin structure assay (SCSA) parameters for the outcome of intrauterine insemination, IVF and ICSI
inferredcites →https://doi.org/10.1093/humrep/del326openalex-snapshot
Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome
inferredcites →https://doi.org/10.1093/humrep/des261openalex-snapshot
The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis
inferredcites →https://doi.org/10.1093/humrep/des417openalex-snapshot
Use of hyaluronan in the selection of sperm for intracytoplasmic sperm injection (ICSI): significant improvement in clinical outcomes—multicenter, double-blinded and randomized controlled trial
inferredcites →https://doi.org/10.1093/humrep/dev251openalex-snapshot
Another look at human sperm morphology
inferredcites →https://doi.org/10.1093/humrep/dey239openalex-snapshot
Microfluidic sorting selects sperm for clinical use with reduced DNA damage compared to density gradient centrifugation with swim-up in split semen samples
inferredcites →https://doi.org/10.1095/biolreprod.103.018184openalex-snapshot
Oocyte Activation after Intracytoplasmic Injection with Sperm Frozen Without Cryoprotectants Results in Live Offspring from Inbred and Hybrid Mouse Strains
inferredcites →https://doi.org/10.1095/biolreprod.106.056952openalex-snapshot
Effect of Transgene Concentration, Flanking Matrix Attachment Regions, and RecA-Coating on the Efficiency of Mouse Transgenesis Mediated by Intracytoplasmic Sperm Injection1
inferredcites →https://doi.org/10.1095/biolreprod.107.065623openalex-snapshot
Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1
inferredcites →https://doi.org/10.1111/(issn)1365-2605openalex-snapshot
International Journal of Andrology
inferredcites →https://doi.org/10.1111/(issn)1447-0756copenalex-snapshot
Journal of Obstetrics and Gynaecology
inferredcites →https://doi.org/10.1111/and.12765openalex-snapshot
Assessment of human sperm DNA integrity using two cytochemical tests: Acridine orange test and toluidine blue assay
inferredcites →https://doi.org/10.1111/j.1365-2605.2008.00874.xopenalex-snapshot
Capacitation‐associated changes in membrane fluidity in asthenozoospermic human spermatozoa
inferredcites →https://doi.org/10.1126/science.162.3857.1035openalex-snapshot
Fertility and Sterility
inferredcites →https://doi.org/10.1262/jrd.2016-112openalex-snapshot
Combination of density gradient centrifugation and swim-up methods effectively decreases morphologically abnormal sperms
inferredcites →https://doi.org/10.1371/journal.pone.0165125openalex-snapshot
Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis
inferredcites →https://doi.org/10.1530/rep-09-0281openalex-snapshot
Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics
inferredcites →https://doi.org/10.1530/rep-17-0374openalex-snapshot
Intracytoplasmic sperm injection: state of the art in humans
inferredcites →https://doi.org/10.3109/01443615.2011.590910openalex-snapshot
The relationship of sperm DNA fragmentation index with the outcomes ofin-vitrofertilisation-embryo transfer and intracytoplasmic sperm injection
inferredcites →https://doi.org/10.3389/fcell.2019.00298openalex-snapshot
Novel Techniques of Sperm Selection for Improving IVF and ICSI Outcomes
inferredcites →https://doi.org/10.4103/0974-1208.192070openalex-snapshot
Ficoll-400 density gradient method as an effective sperm preparation technique for assisted reproductive techniques
inferredcites →https://doi.org/10.4103/1008-682x.153309openalex-snapshot
New insights into the regulation of cholesterol efflux from the sperm membrane
inferredcites →https://doi.org/10.4103/1008-682x.154308openalex-snapshot
Behavioral mechanisms of mammalian sperm guidance
inferredcites →https://doi.org/10.4103/1008-682x.179161openalex-snapshot
Current updates on laboratory techniques for the diagnosis of male reproductive failure
inferredcites →https://doi.org/10.5653/cerm.2017.44.3.132openalex-snapshot
ICSI significantly improved the pregnancy rate of patients with a high sperm DNA fragmentation index
inferredcites →https://doi.org/10.7554/elife.02403openalex-snapshot
Rheotaxis facilitates upstream navigation of mammalian sperm cells
inferredcites →https://doi.org/10.7860/jcdr/2015/10332.6811openalex-snapshot
Frequency of Sperm DNA Fragmentation According to Selection Method: Comparison and Relevance of a Microfluidic Device and a Swim-up Procedure

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.12688/openreseurope.16671.1zenodo-depositor-declared
Lab-on-chip (LoC) application for quality sperm selection: An undelivered promise?
inferred← citeshttps://doi.org/10.1007/978-1-0716-4406-5_2openalex-snapshot
Evolutionary Aspects of Sperm Physiology and Its Assessment
inferred← citeshttps://doi.org/10.1007/s42242-024-00306-1openalex-snapshot
Microfluidic thermotaxic selection of highly motile sperm and in vitro fertilization
inferred← citeshttps://doi.org/10.1016/b978-0-323-93047-5.00033-7openalex-snapshot
Techniques for selection of surgically retrieved sperm for intracytoplasmic sperm injection
inferred← citeshttps://doi.org/10.1016/j.anireprosci.2021.106849openalex-snapshot
Assessment of sperm motility in livestock: Perspectives based on sperm swimming conditions in vivo
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113567openalex-snapshot
Oviduct-mimicking microfluidic chips decreased the ROS concentration in the in vitro fertilized embryos of CD-1 mice
inferred← citeshttps://doi.org/10.1016/j.cct.2022.106893openalex-snapshot
Rationale and study design of a double-blinded prospective randomized clinical trial comparing euploidy rates among embryos created from sibling oocytes injected with sperm processed by microfluidics or by density gradient centrifugation
inferred← citeshttps://doi.org/10.1016/j.cej.2026.175045openalex-snapshot
Towards high-performance sperm selection: Decoding sperm-biointerface dynamics for next-generation microfluidic sorting platforms
inferred← citeshttps://doi.org/10.1016/j.jbiomech.2024.112336openalex-snapshot
Prediction of Sperm Motion Behavior in Microfluidic Channel Using Sperm Swimming Model
inferred← citeshttps://doi.org/10.1016/j.medre.2022.100121openalex-snapshot
Sperm DNA fragmentation and microfluidics: A new era in human sperm selection
inferred← citeshttps://doi.org/10.1016/j.urolonc.2022.03.012openalex-snapshot
The design basis and application in urology of the tumor-on-a-chip platform
inferred← citeshttps://doi.org/10.1016/j.xcrp.2023.101646openalex-snapshot
The cooperative impact of flow and viscosity on sperm flagellar energetics in biomimetic environments
inferred← citeshttps://doi.org/10.1016/j.xcrp.2025.103028openalex-snapshot
Biomimetic angular microfluidic platform for onsite selection of high-quality animal sperm
inferred← citeshttps://doi.org/10.1017/s0967199422000132openalex-snapshot
Comparison of sperm preparation methods to improve the recovery of mature spermatozoa in sub-fertile males
inferred← citeshttps://doi.org/10.1038/s41585-025-01123-6openalex-snapshot
Sperm DNA fragmentation and its influence on mammalian reproduction
inferred← citeshttps://doi.org/10.1038/s41598-024-61617-yopenalex-snapshot
Impact of various cryo-preservation steps on sperm rheotaxis and sperm kinematics in bull
inferred← citeshttps://doi.org/10.1038/s42003-023-04875-2openalex-snapshot
Human sperm cooperate to transit highly viscous regions on the competitive pathway to fertilization
inferred← citeshttps://doi.org/10.1039/d1lc01144hopenalex-snapshot
Lab on a chip devices for fertility: from proof-of-concept to clinical impact
inferred← citeshttps://doi.org/10.1039/d2lc00150kopenalex-snapshot
Rheotaxis quality index: a new parameter that reveals male mammalian in vivo fertility and low sperm DNA fragmentation
inferred← citeshttps://doi.org/10.1039/d3lc00737eopenalex-snapshot
Faster sperm selected by rheotaxis leads to superior early embryonic development in vitro
inferred← citeshttps://doi.org/10.1039/d3lc00893bopenalex-snapshot
Bio-inspired progressive motile sperm separation using joint rheotaxis and boundary-following behavior
inferred← citeshttps://doi.org/10.1063/5.0233544openalex-snapshot
Tunable motile sperm separation based on sperm persistence in migrating through shear barriers
inferred← citeshttps://doi.org/10.1080/19396368.2022.2141154openalex-snapshot
Rheotaxis of sperm in fertile and infertile men
inferred← citeshttps://doi.org/10.1088/1478-3975/ad7b1aopenalex-snapshot
Exploring sperm cell rheotaxis in microfluidic channel: the role of flow and viscosity
inferred← citeshttps://doi.org/10.1088/2516-1091/adf92fopenalex-snapshot
Design clues for motility and rheotaxis-based microfluidic chips for sperm sorting
inferred← citeshttps://doi.org/10.1093/reprod/xaag067openalex-snapshot
Thigmotactic navigation and functional enrichment of boar sperm in microfluidic channels
inferred← citeshttps://doi.org/10.1186/s12951-023-02258-7openalex-snapshot
Revolutionizing the female reproductive system research using microfluidic chip platform
inferred← citeshttps://doi.org/10.1590/1984-3143-ar2026-0061openalex-snapshot
Let the female tract choose: finding the sperm to enhance in vitro embryo production
inferred← citeshttps://doi.org/10.21203/rs.3.rs-4351721/v1openalex-snapshot
Separation of sperm based on rheotaxis mechanism using microfluidic device
inferred← citeshttps://doi.org/10.3389/fcell.2022.961623openalex-snapshot
Biological benefits of collective swimming of sperm in a viscoelastic fluid
inferred← citeshttps://doi.org/10.3390/ani11041034openalex-snapshot
Effect of D-Glucuronic Acid and N-acetyl-D-Glucosamine Treatment during In Vitro Maturation on Embryonic Development after Parthenogenesis and Somatic Cell Nuclear Transfer in Pigs
inferred← citeshttps://doi.org/10.5653/cerm.2024.07304openalex-snapshot
Separation of sperm based on rheotaxis mechanism using a microfluidic device
inferred← citeshttps://doi.org/10.5772/intechopen.1007418openalex-snapshot
Natural Sperm Selection: Perspectives for More Successful Outcomes in ICSI
inferred← citeshttps://doi.org/10.64898/2026.06.03.729852openalex-snapshot
Shear-Induced Oscillations and Hydrodynamic Buffering Stabilize Sperm Surface Navigation
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