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Circulating Bone Marrow-Derived Osteoblast Progenitor Cells Are Recruited to the Bone-Forming Site by the CXCR4/Stromal Cell-Derived Factor-1 Pathway
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1 of the 52 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1038/nature00870 (notice 2024-06-17).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/jbm.1222openalex-snapshotNovel hydroxyapatite ceramics with an interconnective porous structure exhibit superior osteoconduction in vivo
inferredcites →https://doi.org/10.1002/jor.20119openalex-snapshotAllogenic peripheral blood derived mesenchymal stem cells (MSCs) enhance bone regeneration in rabbit ulna critical-sized bone defect model
inferredcites →https://doi.org/10.1038/382635a0openalex-snapshotDefects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1
inferredcites →https://doi.org/10.1038/6529openalex-snapshotTransplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
inferredcites →https://doi.org/10.1038/ni1251openalex-snapshotChemokine receptor CXCR4–dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells
inferredcites →https://doi.org/10.1038/nm1075openalex-snapshotProgenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
inferredcites →https://doi.org/10.1073/pnas.0408258102openalex-snapshotDirected migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1α/CXC chemokine receptor 4 pathway
inferredcites →https://doi.org/10.1073/pnas.92.11.4857openalex-snapshotCultured adherent cells from marrow can serve as long-lasting precursor cells for bone, cartilage, and lung in irradiated mice.
inferredcites →https://doi.org/10.1073/pnas.93.25.14726openalex-snapshotMolecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin
inferredcites →https://doi.org/10.1084/jem.185.1.111openalex-snapshotThe Chemokine SDF-1 Is a Chemoattractant for Human CD34+ Hematopoietic Progenitor Cells and Provides a New Mechanism to Explain the Mobilization of CD34+ Progenitors to Peripheral Blood
inferredcites →https://doi.org/10.1089/scd.1.1997.6.447openalex-snapshotHuman Bone Marrow-Derived Mesenchymal (Stromal) Progenitor Cells (MPCs) Cannot Be Recovered from Peripheral Blood Progenitor Cell Collections
inferredcites →https://doi.org/10.1634/stemcells.21-3-363openalex-snapshotExpression of Functional CXCR4 by Muscle Satellite Cells and Secretion of SDF-1 by Muscle-Derived Fibroblasts is Associated with the Presence of Both Muscle Progenitors in Bone Marrow and Hematopoietic Stem/Progenitor Cells in Muscles
inferredcites →https://doi.org/10.1634/stemcells.22-3-415openalex-snapshotInteractions of Chemokines and Chemokine Receptors Mediate the Migration of Mesenchymal Stem Cells to the Impaired Site in the Brain After Hypoglossal Nerve Injury
inferredcites →https://doi.org/10.3727/000000004783983819openalex-snapshotBone Tissue Engineering Using Novel Interconnected Porous Hydroxyapatite Ceramics Combined with Marrow Mesenchymal Cells: Quantitative and Three-Dimensional Image Analysis
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.3986891openalex-extractedSustained Local Ionic Homeostatic Imbalance (SLIHI) Caused by Calcification Modulates Inflammation to Trigger Ectopic Bone Formation
inferred← citeshttps://doi.org/10.1002/advs.202100584openalex-snapshotN2‐Polarized Neutrophils Guide Bone Mesenchymal Stem Cell Recruitment and Initiate Bone Regeneration: A Missing Piece of the Bone Regeneration Puzzle
inferred← citeshttps://doi.org/10.1002/art.24330openalex-snapshotStromal cell–derived factor 1/CXCR4 signaling is critical for the recruitment of mesenchymal stem cells to the fracture site during skeletal repair in a mouse model
inferred← citeshttps://doi.org/10.1002/bdrc.21047openalex-snapshotOsteoblast recruitment to sites of bone formation in skeletal development, homeostasis, and regeneration
inferred← citeshttps://doi.org/10.1002/jbmr.1562openalex-snapshotMultipotent progenitors resident in the skeletal muscle interstitium exhibit robust BMP-dependent osteogenic activity and mediate heterotopic ossification
inferred← citeshttps://doi.org/10.1002/jbmr.1938openalex-snapshotUbiquitin E3 ligase Wwp1 negatively regulates osteoblast function by inhibiting osteoblast differentiation and migration
inferred← citeshttps://doi.org/10.1002/jbmr.2318openalex-snapshotSDF-1/CXCR4 Axis in Tie2-Lineage Cells Including Endothelial Progenitor Cells Contributes to Bone Fracture Healing
inferred← citeshttps://doi.org/10.1002/jbmr.4204openalex-snapshotBone From Blood: Characteristics and Clinical Implications of Circulating Osteogenic Progenitor (COP) Cells
inferred← citeshttps://doi.org/10.1002/jor.21374openalex-snapshotStromal cell‐derived factor‐1 and monocyte chemotactic protein‐3 improve recruitment of osteogenic cells into sites of musculoskeletal repair
inferred← citeshttps://doi.org/10.1002/jor.22103openalex-snapshotLow‐intensity pulsed ultrasound accelerates fracture healing by stimulation of recruitment of both local and circulating osteogenic progenitors
inferred← citeshttps://doi.org/10.1002/jor.22181openalex-snapshotCurrent insights on the regenerative potential of the periosteum: Molecular, cellular, and endogenous engineering approaches
inferred← citeshttps://doi.org/10.1002/jor.22487openalex-snapshotSkeletal trauma generates systemic BMP2 activation that is temporally related to the mobilization of CD73+ cells
inferred← citeshttps://doi.org/10.1002/jor.22749openalex-snapshotMesenchymal stem cell expression of stromal cell‐derived factor‐1β augments bone formation in a model of local regenerative therapy
inferred← citeshttps://doi.org/10.1002/micr.30548openalex-snapshotEvaluation of dual release of stromal cell‐derived factor‐1 and basic fibroblast growth factor with nerve conduit for peripheral nerve regeneration: An experimental study in mice
inferred← citeshttps://doi.org/10.1002/reg2.81openalex-snapshotThe periosteal requirement and temporal dynamics of BMP2‐induced middle phalanx regeneration in the adult mouse
inferred← citeshttps://doi.org/10.1002/stem.1844openalex-snapshotAdiponectin Regulates Bone Marrow Mesenchymal Stem Cell Niche Through a Unique Signal Transduction Pathway: An Approach for Treating Bone Disease in Diabetes
inferred← citeshttps://doi.org/10.1002/stem.1900openalex-snapshotEndogenous Mesenchymal Stromal Cells in Bone Marrow Are Required to Preserve Muscle Function in mdx Mice
inferred← citeshttps://doi.org/10.1002/stem.2440openalex-snapshotCXCR4+CD45− Cells are Niche Forming for Osteoclastogenesis via the SDF-1, CXCL7, and CX3CL1 Signaling Pathways in Bone Marrow
inferred← citeshttps://doi.org/10.1002/stem.406openalex-snapshotPhagocytosis of Apoptotic Cells Modulates Mesenchymal Stem Cells Osteogenic Differentiation to Enhance IL-17 and RANKL Expression on CD4+ T Cells
inferred← citeshttps://doi.org/10.1002/stem.743openalex-snapshotLimbal Epithelial Stem/Progenitor Cells Attract Stromal Niche Cells by SDF-1/CXCR4 Signaling to Prevent Differentiation
inferred← citeshttps://doi.org/10.1002/term.2078openalex-snapshotMesenchymal stem cell expression of SDF-1βsynergizes with BMP-2 to augment cell-mediated healing of critical-sized mouse calvarial defects
inferred← citeshttps://doi.org/10.1002/term.542openalex-snapshotAnalysis of circulating mesenchymal progenitor cells in arterial and venous blood after fracture
inferred← citeshttps://doi.org/10.1007/978-3-030-84744-9_1openalex-snapshotThe Stem and Progenitor Cell Paradigms and Engineering Principles Guiding the Clinical Use of Cells or Cell-Derived Products for Regenerative Medicine
inferred← citeshttps://doi.org/10.1007/s10165-010-0357-8openalex-snapshotChemokines in mesenchymal stem cell therapy for bone repair: a novel concept of recruiting mesenchymal stem cells and the possible cell sources
inferred← citeshttps://doi.org/10.1007/s40883-018-0052-4openalex-snapshotLocalized SDF-1α Delivery Increases Pro-Healing Bone Marrow-Derived Cells in the Supraspinatus Muscle Following Severe Rotator Cuff Injury
inferred← citeshttps://doi.org/10.1016/j.actbio.2018.02.019openalex-snapshotExogenous stromal derived factor-1 releasing silk scaffold combined with intra-articular injection of progenitor cells promotes bone-ligament-bone regeneration
inferred← citeshttps://doi.org/10.1016/j.bbagen.2018.04.016openalex-snapshotSTAT-3 regulation of CXCR4 is necessary for the prenylflavonoid Icaritin to enhance mesenchymal stem cell proliferation, migration and osteogenic differentiation
inferred← citeshttps://doi.org/10.1016/j.bone.2016.08.009openalex-snapshotBoning up on DPP4, DPP4 substrates, and DPP4-adipokine interactions: Logical reasoning and known facts about bone related effects of DPP4 inhibitors
inferred← citeshttps://doi.org/10.1016/j.joen.2018.10.007openalex-snapshotEndodontic Infection–induced Inflammation Resembling Osteomyelitis of the Jaws in Toll-like Receptor 2/Interleukin 10 Double-knockout Mice
inferred← citeshttps://doi.org/10.1016/j.metabol.2011.09.006openalex-snapshotAssociation between thyroid hormone levels, the number of circulating osteoprogenitor cells, and bone mineral density in euthyroid postmenopausal women
inferred← citeshttps://doi.org/10.1016/j.mtbio.2025.101759openalex-snapshotA novel strategy for bone defect repair: Stromal cell-derived factor 1α sustained-release acellular fish scale scaffolds combined with injection of bone marrow mesenchymal stem cells promote bone regeneration
inferred← citeshttps://doi.org/10.1038/srep11008openalex-snapshotSystemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα+ mesenchymal cells from bone marrow
inferred← citeshttps://doi.org/10.1038/srep16574openalex-snapshotIdentification of a New Cell Population Constitutively Circulating in Healthy Conditions and Endowed with a Homing Ability Toward Injured Sites
inferred← citeshttps://doi.org/10.1039/c8bm00473kopenalex-snapshotThe effects of Sr-incorporated micro/nano rough titanium surface on rBMSC migration and osteogenic differentiation for rapid osteointegration
inferred← citeshttps://doi.org/10.1039/c8bm00846aopenalex-snapshotRecombinant human BMP-2 accelerates the migration of bone marrow mesenchymal stem cells via the CDC42/PAK1/LIMK1 pathway in vitro and in vivo
inferred← citeshttps://doi.org/10.1074/jbc.m111.250985openalex-snapshotConditional Inactivation of the CXCR4 Receptor in Osteoprecursors Reduces Postnatal Bone Formation Due to Impaired Osteoblast Development
inferred← citeshttps://doi.org/10.1089/scd.2016.0067openalex-snapshotReceptor for Advanced Glycation End Products-Mediated Signaling Impairs the Maintenance of Bone Marrow Mesenchymal Stromal Cells in Diabetic Model Mice
inferred← citeshttps://doi.org/10.1089/ten.tea.2009.0322openalex-snapshotControlled Release of Bone Morphogenetic Protein-2 Enhances Recruitment of Osteogenic Progenitor Cells for De Novo Generation of Bone Tissue
inferred← citeshttps://doi.org/10.1089/ten.tea.2012.0085openalex-snapshotStromal Cell-Derived Factor-1β Potentiates Bone Morphogenetic Protein-2-Stimulated Osteoinduction of Genetically Engineered Bone Marrow-Derived Mesenchymal Stem Cells In Vitro
inferred← citeshttps://doi.org/10.1089/ten.tea.2013.0442openalex-snapshotLow-Dose Bone Morphogenetic Protein-2/Stromal Cell-Derived Factor-1β Cotherapy Induces Bone Regeneration in Critical-Size Rat Calvarial Defects
inferred← citeshttps://doi.org/10.1096/fj.202001273ropenalex-snapshotPolyfunctionality of the CXCR4/CXCL12 axis in health and disease: Implications for therapeutic interventions in cancer and immune‐mediated diseases
inferred← citeshttps://doi.org/10.1111/bjh.16389openalex-snapshotEditorial comment: variables affecting the presence of mesenchymal stromal cells in the peripheral blood and their relationship with apheresis product
inferred← citeshttps://doi.org/10.1111/cpr.12286openalex-snapshotPTH / SDF ‐1α cotherapy promotes proliferation, migration and osteogenic differentiation of human periodontal ligament stem cells
inferred← citeshttps://doi.org/10.1111/jre.12433openalex-snapshotRecruitment of bone marrow‐derived cells to the periodontal ligament via the stromal cell‐derived factor‐1/C‐X‐C chemokine receptor type 4 axis
inferred← citeshttps://doi.org/10.1124/jpet.118.254367openalex-snapshotFacilitation of Chemotaxis Activity of Mesenchymal Stem Cells via Stromal Cell–Derived Factor-1 and Its Receptor May Promote Ectopic Ossification of Human Spinal Ligaments
inferred← citeshttps://doi.org/10.1182/blood-2010-01-266833openalex-snapshotLoss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression
inferred← citeshttps://doi.org/10.1186/s13075-025-03691-9openalex-snapshotTargeting the CXCL12/CXCR4 pathway by an optimized derivative or EPI-X4 preserves chondrocyte function and offers a novel therapeutic approach in rheumatic diseases
inferred← citeshttps://doi.org/10.1186/s13550-018-0463-8openalex-snapshotBone marrow cell homing to sites of acute tibial fracture: 89Zr-oxine cell labeling with positron emission tomographic imaging in a mouse model
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