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FARSB serves as a novel hypomethylated and immune cell infiltration related prognostic biomarker in hepatocellular carcinoma

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hep.20933openalex-snapshot
Management of Hepatocellular Carcinoma *
inferredcites →https://doi.org/10.1002/hep.25706openalex-snapshot
Characteristic patterns of altered DNA methylation predict emergence of human hepatocellular carcinoma
inferredcites →https://doi.org/10.1002/hep.25907openalex-snapshot
Overexpression of CXCL5 mediates neutrophil infiltration and indicates poor prognosis for hepatocellular carcinoma
inferredcites →https://doi.org/10.1002/hep.28655openalex-snapshot
Hypoxia induces myeloid‐derived suppressor cell recruitment to hepatocellular carcinoma through chemokine (C‐C motif) ligand 26
inferredcites →https://doi.org/10.1002/humu.23595openalex-snapshot
Homozygosity for FARSB mutation leads to Phe-tRNA synthetase-related disease of growth restriction, brain calcification, and interstitial lung disease
inferredcites →https://doi.org/10.1002/pro.3307openalex-snapshot
The human protein atlas: A spatial map of the human proteome
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Extracellular Activities of Aminoacyl-tRNA Synthetases: New Mediators for Cell–Cell Communication
inferredcites →https://doi.org/10.1007/s00432-004-0552-0openalex-snapshot
Randomized controlled trial of screening for hepatocellular carcinoma
inferredcites →https://doi.org/10.1007/s12033-016-9947-9openalex-snapshot
N 6-Methyladenosine (m6A) Methylation in mRNA with A Dynamic and Reversible Epigenetic Modification
inferredcites →https://doi.org/10.1007/s13277-015-3626-5openalex-snapshot
Rab31 promoted hepatocellular carcinoma (HCC) progression via inhibition of cell apoptosis induced by PI3K/AKT/Bcl-2/BAX pathway
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The protective effects of curcumin on metabolic syndrome and its components: In-silico analysis for genes, transcription factors, and microRNAs involved
inferredcites →https://doi.org/10.1016/j.cellsig.2022.110302openalex-snapshot
GARS is implicated in poor survival and immune infiltration of hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/j.gendis.2020.01.014openalex-snapshot
Advances in the early diagnosis of hepatocellular carcinoma
inferredcites →https://doi.org/10.1016/j.gpb.2018.07.003openalex-snapshot
HCCDB: A Database of Hepatocellular Carcinoma Expression Atlas
inferredcites →https://doi.org/10.1016/j.jaci.2014.10.013openalex-snapshot
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis
inferredcites →https://doi.org/10.1016/j.jbc.2021.100608openalex-snapshot
How the Protein Data Bank changed biology: An introduction to the JBC Reviews thematic series, part 1
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UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
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The regulatory roles of aminoacyl-tRNA synthetase in cardiovascular disease
inferredcites →https://doi.org/10.1016/j.tibs.2005.08.004openalex-snapshot
Functional expansion of aminoacyl-tRNA synthetases and their interacting factors: new perspectives on housekeepers
inferredcites →https://doi.org/10.1016/j.yexcr.2009.02.007openalex-snapshot
Rplp1 bypasses replicative senescence and contributes to transformation
inferredcites →https://doi.org/10.1016/s0002-9270(02)06049-5openalex-snapshot
Screening for Hepatocellular Carcinoma in Patients With Hepatitis C Cirrhosis: A Cost-Utility Analysis
inferredcites →https://doi.org/10.1016/s1470-2045(12)70490-4openalex-snapshot
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study
inferredcites →https://doi.org/10.1021/acsptsci.8b00001openalex-snapshot
Stabilization of Cyclin-Dependent Kinase 4 by Methionyl-tRNA Synthetase in p16 INK4a -Negative Cancer
inferredcites →https://doi.org/10.1038/d41573-019-00167-9openalex-snapshot
Immuno-oncology drug development goes global
inferredcites →https://doi.org/10.1038/d41573-019-00182-wopenalex-snapshot
Trends in clinical development for PD-1/PD-L1 inhibitors
inferredcites →https://doi.org/10.1038/nature06309openalex-snapshot
Adaptive immunity maintains occult cancer in an equilibrium state
inferredcites →https://doi.org/10.1038/ng.2291openalex-snapshot
Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators
inferredcites →https://doi.org/10.1038/ng.3126openalex-snapshot
Trans-ancestry mutational landscape of hepatocellular carcinoma genomes
inferredcites →https://doi.org/10.1038/ng.3252openalex-snapshot
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets
inferredcites →https://doi.org/10.1038/nm.3394openalex-snapshot
Microenvironmental regulation of tumor progression and metastasis
inferredcites →https://doi.org/10.1038/nrc3124openalex-snapshot
Aminoacyl-tRNA synthetases and tumorigenesis: more than housekeeping
inferredcites →https://doi.org/10.1038/nrg3724openalex-snapshot
Gene expression regulation mediated through reversible m6A RNA methylation
inferredcites →https://doi.org/10.1038/nri.2016.80openalex-snapshot
Regulatory circuits of T cell function in cancer
inferredcites →https://doi.org/10.1038/s41416-018-0328-yopenalex-snapshot
Cytokines in clinical cancer immunotherapy
inferredcites →https://doi.org/10.1038/s41419-018-1224-3openalex-snapshot
m6A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression
inferredcites →https://doi.org/10.1038/s41419-021-03973-5openalex-snapshot
MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma
inferredcites →https://doi.org/10.1038/s41419-021-04238-xopenalex-snapshot
LncRNA SNHG17 interacts with LRPPRC to stabilize c-Myc protein and promote G1/S transition and cell proliferation
inferredcites →https://doi.org/10.1038/s41419-022-04544-yopenalex-snapshot
Correction: m6A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression
inferredcites →https://doi.org/10.1038/s41556-018-0174-4openalex-snapshot
m6A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer
inferredcites →https://doi.org/10.1038/s41573-019-0026-3openalex-snapshot
Aminoacyl-tRNA synthetases as therapeutic targets
inferredcites →https://doi.org/10.1038/s41575-018-0089-3openalex-snapshot
Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators
inferredcites →https://doi.org/10.1038/s41591-018-0014-xopenalex-snapshot
Understanding the tumor immune microenvironment (TIME) for effective therapy
inferredcites →https://doi.org/10.1053/j.gastro.2014.06.043openalex-snapshot
Roles for Chemokines in Liver Disease
inferredcites →https://doi.org/10.1053/j.seminoncol.2012.05.009openalex-snapshot
New Serum Markers of Hepatocellular Carcinoma
inferredcites →https://doi.org/10.1080/15384101.2021.1958502openalex-snapshot
DTYMK promote hepatocellular carcinoma proliferation by regulating cell cycle
inferredcites →https://doi.org/10.1080/2162402x.2015.1105430openalex-snapshot
Inflammatory regulatory T cells in the microenvironments of ulcerative colitis and colon carcinoma
inferredcites →https://doi.org/10.1093/bioinformatics/bty411openalex-snapshot
GSCALite: a web server for gene set cancer analysis
inferredcites →https://doi.org/10.1093/nar/28.1.235openalex-snapshot
The Protein Data Bank
inferredcites →https://doi.org/10.1093/nar/gkaa1020openalex-snapshot
TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment
inferredcites →https://doi.org/10.1093/nar/gkx1090openalex-snapshot
LinkedOmics: analyzing multi-omics data within and across 32 cancer types
inferredcites →https://doi.org/10.1093/nar/gkx247openalex-snapshot
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
inferredcites →https://doi.org/10.1093/nar/gkx778openalex-snapshot
N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
inferredcites →https://doi.org/10.1093/nar/gky1131openalex-snapshot
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
inferredcites →https://doi.org/10.1097/00004728-200109000-00018openalex-snapshot
Detection of Hepatocellular Carcinoma: Combined T2-Weighted and Dynamic Gadolinium-Enhanced MRI Versus Combined CT During Arterial Portography and CT Hepatic Arteriography
inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
inferredcites →https://doi.org/10.1111/febs.14090openalex-snapshot
Metabolic reprogramming and epithelial‐to‐mesenchymal transition in cancer
inferredcites →https://doi.org/10.1111/j.1398-9995.2012.02870.xopenalex-snapshot
CX 3 CL 1 in allergic diseases: not just a chemotactic molecule
inferredcites →https://doi.org/10.1111/jgh.15592openalex-snapshot
Contribution of upregulated aminoacyl‐tRNA biosynthesis to metabolic dysregulation in gastric cancer
inferredcites →https://doi.org/10.1126/sciimmunol.aaz8128openalex-snapshot
A new perspective in cancer immunotherapy: PD-1 on myeloid cells takes center stage in orchestrating immune checkpoint blockade
inferredcites →https://doi.org/10.1126/scisignal.2004088openalex-snapshot
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
inferredcites →https://doi.org/10.1136/gutjnl-2014-307323openalex-snapshot
Moving towards personalised therapy in patients with hepatocellular carcinoma: the role of the microenvironment
inferredcites →https://doi.org/10.1136/gutjnl-2014-307671openalex-snapshot
Tim-3 fosters HCC development by enhancing TGF-β-mediated alternative activation of macrophages
inferredcites →https://doi.org/10.1158/0008-5472.can-05-3740openalex-snapshot
AIMP3 Haploinsufficiency Disrupts Oncogene-Induced p53 Activation and Genomic Stability
inferredcites →https://doi.org/10.1158/0008-5472.can-17-0307openalex-snapshot
TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-18-3962openalex-snapshot
The Tumor Microenvironment Innately Modulates Cancer Progression
inferredcites →https://doi.org/10.1186/s12935-021-02163-9openalex-snapshot
Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma
inferredcites →https://doi.org/10.1186/s12943-016-0502-xopenalex-snapshot
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
inferredcites →https://doi.org/10.1186/s12943-017-0727-3openalex-snapshot
Linc-RoR promotes MAPK/ERK signaling and confers estrogen-independent growth of breast cancer
inferredcites →https://doi.org/10.1186/s12943-018-0858-1openalex-snapshot
Tumor microenvironment participates in metastasis of pancreatic cancer
inferredcites →https://doi.org/10.1186/s13046-021-01968-wopenalex-snapshot
Advances in drug development for hepatocellular carcinoma: clinical trials and potential therapeutic targets
inferredcites →https://doi.org/10.1186/s13256-018-1762-4openalex-snapshot
Synchronous double primary hepatic cancer consisting of hepatocellular carcinoma and cholangiolocellular carcinoma: a case report
inferredcites →https://doi.org/10.1186/s40164-021-00218-1openalex-snapshot
PCSK9 promotes tumor growth by inhibiting tumor cell apoptosis in hepatocellular carcinoma
inferredcites →https://doi.org/10.1186/s40425-018-0349-3openalex-snapshot
Current landscape and future of dual anti-CTLA4 and PD-1/PD-L1 blockade immunotherapy in cancer; lessons learned from clinical trials with melanoma and non-small cell lung cancer (NSCLC)
inferredcites →https://doi.org/10.2147/jir.s296597openalex-snapshot
FUT7 Promotes the Epithelial–Mesenchymal Transition and Immune Infiltration in Bladder Urothelial Carcinoma
inferredcites →https://doi.org/10.2174/1574888x13666180816114809openalex-snapshot
Mesenchymal Stem Cells, Immune Cells and Tumor Cells Crosstalk: A Sinister Triangle in the Tumor Microenvironment
inferredcites →https://doi.org/10.3322/caac.21166openalex-snapshot
Cancer statistics, 2013
inferredcites →https://doi.org/10.3389/fcell.2021.728574openalex-snapshot
Genomic Instability of Mutation-Derived Gene Prognostic Signatures for Hepatocellular Carcinoma
inferredcites →https://doi.org/10.3389/fgene.2020.00427openalex-snapshot
Bioinformatics Analysis Reveals Biomarkers With Cancer Stem Cell Characteristics in Lung Squamous Cell Carcinoma
inferredcites →https://doi.org/10.3389/fgene.2022.825685openalex-snapshot
Upregulation of Ferroptosis-Related Fanconi Anemia Group D2 is a Poor Prognostic Factor and an Indicator of Tumor Immune Cell Infiltration in Lung Adenocarcinoma
inferredcites →https://doi.org/10.3389/fonc.2019.01502openalex-snapshot
Prognostic and Immunological Role of FUN14 Domain Containing 1 in Pan-Cancer: Friend or Foe?
inferredcites →https://doi.org/10.3389/fonc.2020.553045openalex-snapshot
m6A Reader HNRNPA2B1 Promotes Esophageal Cancer Progression via Up-Regulation of ACLY and ACC1
inferredcites →https://doi.org/10.3389/fonc.2020.586414openalex-snapshot
A Comprehensive Prognostic and Immune Analysis of SLC41A3 in Pan-Cancer
inferredcites →https://doi.org/10.3390/cells9061370openalex-snapshot
Biomarkers in Hepatocellular Carcinoma: Diagnosis, Prognosis and Treatment Response Assessment
inferredcites →https://doi.org/10.3390/ijms16036571openalex-snapshot
Aminoacyl-tRNA Synthetase Complexes in Evolution
inferredcites →https://doi.org/10.3390/ijms20215347openalex-snapshot
PD-L1/PD-1 Axis in Glioblastoma Multiforme
inferredcites →https://doi.org/10.3390/ijms21030879openalex-snapshot
The Role of Immune Checkpoint Blockade in Uveal Melanoma
inferredcites →https://doi.org/10.3748/wjg.v21.i37.10573openalex-snapshot
Biomarkers for the early diagnosis of hepatocellular carcinoma
inferredcites →https://doi.org/10.3748/wjg.v25.i29.4199openalex-snapshot
Multiple “Omics” data-based biomarker screening for hepatocellular carcinoma diagnosis
inferredcites →https://doi.org/10.3892/etm.2021.10184openalex-snapshot
RPLP1 is highly expressed in hepatocellular carcinoma tissues and promotes proliferation, invasion and migration of human hepatocellular carcinoma Hep3b cells
inferredcites →https://doi.org/10.4049/jimmunol.1003251openalex-snapshot
IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer
inferredcites →https://doi.org/10.7554/elife.34362openalex-snapshot
Wnt5a signaling induced phosphorylation increases APT1 activity and promotes melanoma metastatic behavior

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1080/07357907.2025.2512379openalex-snapshot
Overexpression FARSB Reveals Poor Prognosis in Breast Cancer and is Correlated with Immunity
inferred← citeshttps://doi.org/10.2147/jhc.s458734openalex-snapshot
Research Progress on the Role of Epigenetic Methylation Modification in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.2174/0113816128326151240820105525openalex-snapshot
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inferred← citeshttps://doi.org/10.3389/fimmu.2024.1442722openalex-snapshot
Elucidating the multifaceted role of MGAT1 in hepatocellular carcinoma: integrative single-cell and spatial transcriptomics reveal novel therapeutic insights
inferred← citeshttps://doi.org/10.3390/ijms242316709openalex-snapshot
FARSB Facilitates Hepatocellular Carcinoma Progression by Activating the mTORC1 Signaling Pathway
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