On the public citation graph

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk

https://doi.org/10.18632/oncotarget.2008

0 signed · 88 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

1 of the 58 references listed on this page is in the Retraction Watch database as retracted (export 2026-11-04): 10.1158/0008-5472.can-10-3121 (notice 2018-09-04).

Dataset join, best-effort; this page does not check the publisher record. Retraction Watch data via Crossref Labs, used with credit; OpenCitations Index (CC0) and Meta (CC BY 4.0); dataset doi:10.7910/DVN/WT8VOA (CC BY 4.0).

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cncr.20947openalex-snapshot

Recent advances in understanding the cell death pathways activated by anticancer therapy

inferredcites →https://doi.org/10.1002/cncr.22427openalex-snapshot

Chemotherapy for metastatic melanoma

inferredcites →https://doi.org/10.1007/s00018-008-8329-2openalex-snapshot

Selenocystine induces apoptosis of A375 human melanoma cells by activating ROS-mediated mitochondrial pathway and p53 phosphorylation

inferredcites →https://doi.org/10.1007/s00204-011-0687-0openalex-snapshot

Anti-apoptotic, anti-inflammatory, and immunomodulatory activities of 3,3′-diselenodipropionic acid in mice exposed to whole body γ-radiation

inferredcites →https://doi.org/10.1016/j.bcp.2008.02.016openalex-snapshot

Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway

inferredcites →https://doi.org/10.1016/j.biocel.2008.07.014openalex-snapshot

Selenocystine induces caspase-independent apoptosis in MCF-7 human breast carcinoma cells with involvement of p53 phosphorylation and reactive oxygen species generation

inferredcites →https://doi.org/10.1016/j.biopha.2007.12.002openalex-snapshot

Mitochondria-mediated apoptosis in human breast carcinoma MCF-7 cells induced by a novel selenadiazole derivative

inferredcites →https://doi.org/10.1016/j.ccr.2007.06.011openalex-snapshot

Clearing the TRAIL for Cancer Therapy

inferredcites →https://doi.org/10.1016/j.cell.2007.06.009openalex-snapshot

AKT/PKB Signaling: Navigating Downstream

inferredcites →https://doi.org/10.1016/j.drup.2004.01.004openalex-snapshot

ROS stress in cancer cells and therapeutic implications

inferredcites →https://doi.org/10.1016/j.drup.2007.09.001openalex-snapshot

Overcoming apoptosis deficiency of melanoma—Hope for new therapeutic approaches

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2009.11.009openalex-snapshot

In vivo radioprotection studies of 3,3′-diselenodipropionic acid, a selenocystine derivative

inferredcites →https://doi.org/10.1016/j.tips.2004.02.009openalex-snapshot

p53: 25 years after its discovery

inferredcites →https://doi.org/10.1016/s0022-3565(24)29450-7openalex-snapshot

Drug Synergism: Its Detection and Applications

inferredcites →https://doi.org/10.1016/s0092-8674(00)80405-5openalex-snapshot

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

inferredcites →https://doi.org/10.1016/s0092-8674(00)80416-xopenalex-snapshot

DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2

inferredcites →https://doi.org/10.1016/s0140-6736(00)02490-9openalex-snapshot

The importance of selenium to human health

inferredcites →https://doi.org/10.1016/s1097-2765(01)00323-9openalex-snapshot

Regulation of PTEN Transcription by p53

inferredcites →https://doi.org/10.1016/s1368-7646(02)00120-6openalex-snapshot

Activation of the PI3K/Akt pathway and chemotherapeutic resistance

inferredcites →https://doi.org/10.1021/jf802125topenalex-snapshot

Selenocystine Induces S-Phase Arrest and Apoptosis in Human Breast Adenocarcinoma MCF-7 Cells by Modulating ERK and Akt Phosphorylation

inferredcites →https://doi.org/10.1021/tx960158qopenalex-snapshot

Generation of Putative Intrastrand Cross-Links and Strand Breaks in DNA by Transition Metal Ion-Mediated Oxygen Radical Attack

inferredcites →https://doi.org/10.1038/5517openalex-snapshot

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

inferredcites →https://doi.org/10.1038/ncb1101-973openalex-snapshot

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

inferredcites →https://doi.org/10.1038/nrc821openalex-snapshot

Targeting death and decoy receptors of the tumour-necrosis factor superfamily

inferredcites →https://doi.org/10.1038/nrc864openalex-snapshot

Live or let die: the cell's response to p53

inferredcites →https://doi.org/10.1038/nrc883openalex-snapshot

The Bcl2 family: regulators of the cellular life-or-death switch

inferredcites →https://doi.org/10.1038/sj.leu.2403044openalex-snapshot

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells

inferredcites →https://doi.org/10.1038/sj.onc.1204736openalex-snapshot

Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer

inferredcites →https://doi.org/10.1038/sj.onc.1205181openalex-snapshot

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

inferredcites →https://doi.org/10.1038/sj.onc.1208742openalex-snapshot

Methylseleninic acid sensitizes prostate cancer cells to TRAIL-mediated apoptosis

inferredcites →https://doi.org/10.1039/c3dt33077jopenalex-snapshot

Zinc(ii) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells

inferredcites →https://doi.org/10.1046/j.1365-2141.2003.04699.xopenalex-snapshot

Chemical sensitization and regulation of TRAIL‐induced apoptosis in a panel of B‐lymphocytic leukaemia cell lines

inferredcites →https://doi.org/10.1054/drup.2001.0214openalex-snapshot

Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy

inferredcites →https://doi.org/10.1074/jbc.m005196200openalex-snapshot

Elevated Akt Activity Protects the Prostate Cancer Cell Line LNCaP from TRAIL-induced Apoptosis

inferredcites →https://doi.org/10.1074/jbc.m109745200openalex-snapshot

Akt Enhances Mdm2-mediated Ubiquitination and Degradation of p53

inferredcites →https://doi.org/10.1074/jbc.m400063200openalex-snapshot

×Phosphorylation of Bax Ser184 by Akt Regulates Its Activity and Apoptosis in Neutrophils

inferredcites →https://doi.org/10.1101/gad.13.22.2905openalex-snapshot

Cellular survival: a play in three Akts

inferredcites →https://doi.org/10.1146/annurev.arplant.55.031903.141701openalex-snapshot

REACTIVE OXYGEN SPECIES: Metabolism, Oxidative Stress, and Signal Transduction

inferredcites →https://doi.org/10.1146/annurev.biochem.73.011303.073723openalex-snapshot

Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints

inferredcites →https://doi.org/10.1158/0008-5472.can-05-2216openalex-snapshot

Expression of p53 Enhances Selenite-Induced Superoxide Production and Apoptosis in Human Prostate Cancer Cells

inferredcites →https://doi.org/10.1158/0008-5472.can-10-3121openalex-snapshot

ROS and CHOP Are Critical for Dibenzylideneacetone to Sensitize Tumor Cells to TRAIL through Induction of Death Receptors and Downregulation of Cell Survival Proteins

inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-3389openalex-snapshot

Sorafenib Overcomes TRAIL Resistance of Hepatocellular Carcinoma Cells through the Inhibition of STAT3

inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0063openalex-snapshot

Inorganic selenium sensitizes prostate cancer cells to TRAIL-induced apoptosis through superoxide/p53/Bax-mediated activation of mitochondrial pathway

inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0643openalex-snapshot

Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates

inferredcites →https://doi.org/10.1186/bcr1276openalex-snapshot

Se-methylselenocysteine inhibits phosphatidylinositol 3-kinase activity of mouse mammary epithelial tumor cells in vitro

inferredcites →https://doi.org/10.1371/journal.pone.0053945openalex-snapshot

Enhancement of Auranofin-Induced Apoptosis in MCF-7 Human Breast Cells by Selenocystine, a Synergistic Inhibitor of Thioredoxin Reductase

inferredcites →https://doi.org/10.1634/theoncologist.9-2-182openalex-snapshot

Recent Advances in Melanoma Biology

inferredcites →https://doi.org/10.18632/oncotarget.1162openalex-snapshot

Combining TRAIL with PI3 Kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling

inferredcites →https://doi.org/10.18632/oncotarget.1500openalex-snapshot

Chloroquine synergizes with FTS to enhance cell growth inhibition and cell death

inferredcites →https://doi.org/10.18632/oncotarget.1628openalex-snapshot

Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress

inferredcites →https://doi.org/10.18632/oncotarget.1854openalex-snapshot

Strategy to enhance the therapeutic effect of doxorubicin in human hepatocellular carcinoma by selenocystine, a synergistic agent that regulates the ROS-mediated signaling

inferredcites →https://doi.org/10.18632/oncotarget.1892openalex-snapshot

Pathways and therapeutic targets in melanoma

inferredcites →https://doi.org/10.18632/oncotarget.240openalex-snapshot

Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health

inferredcites →https://doi.org/10.18632/oncotarget.277openalex-snapshot

Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link

inferredcites →https://doi.org/10.18632/oncotarget.652openalex-snapshot

Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response.

inferredcites →https://doi.org/10.18632/oncotarget.762openalex-snapshot

A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia

inferredcites →https://doi.org/10.2174/1568009043481614openalex-snapshot

Apoptosis is a Critical Cellular Event in Cancer Chemoprevention and Chemotherapy by Selenium Compounds

inferredcites →https://doi.org/10.4161/cbt.5.5.2654openalex-snapshot

Selenomethionine induces p53 mediated cell cycle arrest and apoptosis in human colon cancer cells

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4765835openalex-extracted

Polyfunctionalized Organoselenides: New Synthetic Approach from Seleno-Containing Cyanohydrins and Anti-Melanoma Activity

inferred← citeshttps://doi.org/10.1002/asia.201700272openalex-snapshot

Enhancement of Antiangiogenic Efficacy of Iron(II) Complex by Selenium Substitution

inferred← citeshttps://doi.org/10.1002/asia.201800110openalex-snapshot

Selenadiazole Derivatives Inhibit Angiogenesis‐Mediated Human Breast Tumor Growth by Suppressing the VEGFR2‐Mediated ERK and AKT Signaling Pathways

inferred← citeshttps://doi.org/10.1002/iub.2727openalex-snapshot

Post‐radiation treatment of 3,3′‐diselenodipropionic acid augments cell kill by modulating DNA repair and cell migration pathways in A549 cells

inferred← citeshttps://doi.org/10.1007/978-3-319-55448-8_3openalex-snapshot

Selenium: Roles in Cancer Prevention and Therapies

inferred← citeshttps://doi.org/10.1007/s11030-025-11221-7openalex-snapshot

Unraveling the role of deuterium in cancer: mechanisms, detection techniques, and therapeutic potential

inferred← citeshttps://doi.org/10.1007/s12035-015-9373-1openalex-snapshot

DSePA Antagonizes High Glucose-Induced Neurotoxicity: Evidences for DNA Damage-Mediated p53 Phosphorylation and MAPKs and AKT Pathways

inferred← citeshttps://doi.org/10.1016/j.bbagen.2020.129768openalex-snapshot

3,3′-Diselenodipropionic acid (DSePA): A redox active multifunctional molecule of biological relevance

inferred← citeshttps://doi.org/10.1016/j.bbrc.2016.03.127openalex-snapshot

Bakuchiol sensitizes cancer cells to TRAIL through ROS- and JNK-mediated upregulation of death receptors and downregulation of survival proteins

inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109261openalex-snapshot

Enhanced anticancer efficiency of doxorubicin against human glioma by natural borneol through triggering ROS-mediated signal

inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129860openalex-snapshot

Polyfunctionalized organoselenides: New synthetic approach from selenium-containing cyanohydrins and anti-melanoma activity

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2021.08.017openalex-snapshot

3,3′-Diselenodipropionic acid (DSePA) induces reductive stress in A549 cells triggering p53-independent apoptosis: A novel mechanism for diselenides

inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2024.135141openalex-snapshot

Diseleno-albumin, a native bio-inspired drug free therapeutic protein induces apoptosis in lung cancer cells through mitochondrial oxidation

inferred← citeshttps://doi.org/10.1016/j.yrtph.2018.09.019openalex-snapshot

Toxicological safety evaluation of 3,3′-diselenodipropionic acid (DSePA), a pharmacologically important derivative of selenocystine

inferred← citeshttps://doi.org/10.1038/s41598-017-06979-2openalex-snapshot

Selenocysteine induces apoptosis in human glioma cells: evidence for TrxR1-targeted inhibition and signaling crosstalk

inferred← citeshttps://doi.org/10.1038/srep09157openalex-snapshot

Ruthenium Polypyridyl Complex Inhibits Growth and Metastasis of Breast Cancer Cells by Suppressing FAK signaling with Enhancement of TRAIL-induced Apoptosis

inferred← citeshttps://doi.org/10.1039/c6dt02045copenalex-snapshot

Highly stable selenadiazole derivatives induce bladder cancer cell apoptosis and inhibit cell migration and invasion through the activation of ROS-mediated signaling pathways

inferred← citeshttps://doi.org/10.1039/c9cc07683bopenalex-snapshot

Rational design and action mechanisms of chemically innovative organoselenium in cancer therapy

inferred← citeshttps://doi.org/10.1039/d4md00105bopenalex-snapshot

Deuterium labeling improves the therapeutic index of 3,3′-diselenodipropionic acid as an anticancer agent: insights from redox reactions

inferred← citeshttps://doi.org/10.1080/10715762.2024.2433988openalex-snapshot

“Reductive stress” the overlooked side of cellular redox modulation in cancer: opportunity for design of next generation redox chemotherapeutics

inferred← citeshttps://doi.org/10.1080/13880209.2019.1703756openalex-snapshot

Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT pathway

inferred← citeshttps://doi.org/10.1093/nutrit/nuad106openalex-snapshot

Nutrition and melanoma: the contribution of trace elements in onset, progression, and treatment of melanoma

inferred← citeshttps://doi.org/10.18632/oncotarget.10582openalex-snapshot

Icariside II overcomes TRAIL resistance of melanoma cells through ROS-mediated downregulation of STAT3/cFLIP signaling

inferred← citeshttps://doi.org/10.18632/oncotarget.15819openalex-snapshot

PPARγ activation by troglitazone enhances human lung cancer cells to TRAIL-induced apoptosis via autophagy flux

inferred← citeshttps://doi.org/10.18632/oncotarget.3426openalex-snapshot

FTY720 enhances TRAIL-mediated apoptosis by up-regulating DR5 and down-regulating Mcl-1 in cancer cells

inferred← citeshttps://doi.org/10.18632/oncotarget.7814openalex-snapshot

Overexpression of pig selenoprotein S blocks OTA-induced promotion of PCV2 replication by inhibiting oxidative stress and p38 phosphorylation in PK15 cells

inferred← citeshttps://doi.org/10.3390/biology12060875openalex-snapshot

New Insights into Oxidative and Reductive Stress Responses and Their Relation to the Anticancer Activity of Selenium-Containing Compounds as Hydrogen Selenide Donors

inferred← citeshttps://doi.org/10.3390/ijms21155302openalex-snapshot

Non-Thermal Plasma Couples Oxidative Stress to TRAIL Sensitization through DR5 Upregulation

inferred← citeshttps://doi.org/10.3390/ijms22031009openalex-snapshot

Selenium Compounds as Novel Potential Anticancer Agents

inferred← citeshttps://doi.org/10.4062/biomolther.2022.017openalex-snapshot

Modulation of Reactive Oxygen Species to Overcome 5-Fluorouracil Resistance

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.