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Glipizide, an antidiabetic drug, suppresses tumor growth and metastasis by inhibiting angiogenesis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/archinte.166.17.1871openalex-snapshot
Diabetes Mellitus and the Risk of Cancer
inferredcites →https://doi.org/10.1002/chin.200442237openalex-snapshot
Diabetes Mellitus: Pathogenesis and Treatment Strategies.
inferredcites →https://doi.org/10.1002/dmrr.736openalex-snapshot
Are sulphonylureas all the same? A cohort study on cardiovascular and cancer‐related mortality
inferredcites →https://doi.org/10.1002/ijc.21600openalex-snapshot
Diabetes mellitus and cancer risk in a population‐based case–controlstudy among men from Montreal, Canada
inferredcites →https://doi.org/10.1002/stem.1376openalex-snapshot
Natriuretic Peptide Receptor A Signaling Regulates Stem Cell Recruitment and Angiogenesis: A Model to Study Linkage Between Inflammation and Tumorigenesis
inferredcites →https://doi.org/10.1007/s00592-008-0083-2openalex-snapshot
Sulphonylureas and cancer: a case–control study
inferredcites →https://doi.org/10.1016/0720-048x(95)00714-2openalex-snapshot
A novel radiological approach for the experimental study of angiogenesis: angiography of the chick embryo and its chorioallantoic membrane
inferredcites →https://doi.org/10.1016/j.bmc.2008.07.003openalex-snapshot
TX-2152: A conformationally rigid and electron-rich diyne analogue of FTY720 with in vivo antiangiogenic activity
inferredcites →https://doi.org/10.1016/j.diabres.2010.08.022openalex-snapshot
Use of sulphonylurea and cancer in type 2 diabetes—The Hong Kong Diabetes Registry
inferredcites →https://doi.org/10.1016/j.resp.2004.09.005openalex-snapshot
Hypoxic incubation creates differential morphological effects during specific developmental critical windows in the embryo of the chicken (Gallus gallus)
inferredcites →https://doi.org/10.1016/s0092-8674(00)80108-7openalex-snapshot
Patterns and Emerging Mechanisms of the Angiogenic Switch during Tumorigenesis
inferredcites →https://doi.org/10.1016/s0167-7799(03)00004-0openalex-snapshot
A new science–business paradigm in anticancer drug development
inferredcites →https://doi.org/10.1021/jm0306273openalex-snapshot
Diabetes Mellitus: Pathogenesis and Treatment Strategies
inferredcites →https://doi.org/10.1038/bjc.1984.66openalex-snapshot
Endothelial proliferation in tumours and normal tissues: Continuous labelling studies
inferredcites →https://doi.org/10.1038/nrc2442openalex-snapshot
Modes of resistance to anti-angiogenic therapy
inferredcites →https://doi.org/10.1038/sj.bjc.6602619openalex-snapshot
Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies
inferredcites →https://doi.org/10.1056/nejm197111182852108openalex-snapshot
Tumor Angiogenesis: Therapeutic Implications
inferredcites →https://doi.org/10.1073/pnas.0408622102openalex-snapshot
Accessing key steps of human tumor progression in vivo by using an avian embryo model
inferredcites →https://doi.org/10.1089/biores.2013.0014openalex-snapshot
A Modified Aggregate Culture for Chondrogenesis of Human Adipose-Derived Stem Cells Genetically Modified with Growth and Differentiation Factor 5
inferredcites →https://doi.org/10.1093/aje/kwh334openalex-snapshot
Diabetes and Risk of Prostate Cancer in a Prospective Cohort of US Men
inferredcites →https://doi.org/10.1093/jnci/82.4.305openalex-snapshot
Expression of the Atrial Natriuretic Factor Gene in small Cell Lung Cancer Tumors and Tumor Cell Lines
inferredcites →https://doi.org/10.1093/jnci/djj015openalex-snapshot
Diabetes Mellitus and Risk of Colorectal Cancer in the Singapore Chinese Health Study
inferredcites →https://doi.org/10.1128/mcb.12.3.954openalex-snapshot
Induction of Mammary Tumors by Expression of Polyomavirus Middle T Oncogene: A Transgenic Mouse Model for Metastatic Disease
inferredcites →https://doi.org/10.1136/gut.2004.052167openalex-snapshot
Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study
inferredcites →https://doi.org/10.1152/ajpheart.1995.268.3.h1139openalex-snapshot
ANP increases capillary permeability to protein independent of perfusate protein composition
inferredcites →https://doi.org/10.1158/0008-5472.can-07-3086openalex-snapshot
Natriuretic Peptide Receptor A as a Novel Anticancer Target
inferredcites →https://doi.org/10.1172/jci23360openalex-snapshot
Vascular endothelium is critically involved in the hypotensive and hypovolemic actions of atrial natriuretic peptide
inferredcites →https://doi.org/10.1186/1476-4598-10-56openalex-snapshot
Natriuretic Peptide Receptor A as a Novel Target for Prostate Cancer
inferredcites →https://doi.org/10.1309/hw2m-yb5t-vf4a-m0y4openalex-snapshot
Hypercholesterolemia Impairs Angiogenesis in Patients With Breast Carcinoma and, Therefore, Lowers the Risk of Metastases
inferredcites →https://doi.org/10.1387/ijdb.9032025openalex-snapshot
The chick embryo chorioallantoic membrane as a model for in vivo research on angiogenesis
inferredcites →https://doi.org/10.18632/aging.100556openalex-snapshot
Metformin, aging and cancer
inferredcites →https://doi.org/10.18632/oncotarget.1864openalex-snapshot
Metformin-induced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells
inferredcites →https://doi.org/10.18632/oncotarget.1965openalex-snapshot
Oncobiguanides: Paracelsus' law and nonconventional routes for administering diabetobiguanides for cancer treatment
inferredcites →https://doi.org/10.18632/oncotarget.248openalex-snapshot
Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture
inferredcites →https://doi.org/10.18632/oncotarget.488openalex-snapshot
Metformin-induced preferential killing of breast cancer initiating CD44+CD24−/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts
inferredcites →https://doi.org/10.2174/092986708783330656openalex-snapshot
Type 2 Diabetes and Oral Antihyperglycemic Drugs
inferredcites →https://doi.org/10.2174/1568009054064624openalex-snapshot
The Chick Embryo Chorioallantoic Membrane as a Model System for the Study of Tumor Angiogenesis, Invasion and Development of Anti-Angiogenic Agents
inferredcites →https://doi.org/10.2337/dc06-0997openalex-snapshot
Increased Cancer-Related Mortality for Patients With Type 2 Diabetes Who Use Sulfonylureas or Insulin
inferredcites →https://doi.org/10.2337/diacare.20.4.597openalex-snapshot
Efficacy, Safety, and Dose-Response Characteristics of Glipizide Gastrointestinal Therapeutic System on Glycemic Control and Insulin Secretion in NIDDM: Results of two multicenter, randomized, placebo-controlled clinical trials

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4765193openalex-extracted
Synergistic Effects of Sulfonylureas with Chemotherapeutics: In Vitro Screening Reveals Enhanced Cytotoxicity of Doxorubicin in Combination with Sulfonylureas
inferred← citeshttps://doi.org/10.1002/ar.23777openalex-snapshot
HMGA1 Overexpression is Associated With the Malignant Status and Progression of Breast Cancer
inferred← citeshttps://doi.org/10.1002/cbin.11051openalex-snapshot
Establishment of an in ovo chick embryo yolk sac membrane (YSM) assay for pilot screening of potential angiogenic and anti‐angiogenic agents
inferred← citeshttps://doi.org/10.1002/ddr.21499openalex-snapshot
Evaluation of selected commercial pharmacotherapeutic drugs as potential pancreatic lipase inhibitors and antiproliferative compounds
inferred← citeshttps://doi.org/10.1002/mco2.70588openalex-snapshot
Loss of Beta‐Cell Identity and Function as a Mechanism of Secondary Failure of Sulfonylurea Therapy in Diabetes
inferred← citeshttps://doi.org/10.1007/978-981-95-4522-3_11openalex-snapshot
Repurposing of Therapeutics for Anticancer Activity
inferred← citeshttps://doi.org/10.1007/s00432-022-03936-zopenalex-snapshot
The 3D in vivo chorioallantoic membrane model and its role in breast cancer research
inferred← citeshttps://doi.org/10.1007/s10456-020-09707-zopenalex-snapshot
Decylubiquinone suppresses breast cancer growth and metastasis by inhibiting angiogenesis via the ROS/p53/ BAI1 signaling pathway
inferred← citeshttps://doi.org/10.1007/s10753-023-01850-1openalex-snapshot
Glipizide Alleviates Periodontitis Pathogenicity via Inhibition of Angiogenesis, Osteoclastogenesis and M1/M2 Macrophage Ratio in Periodontal Tissue
inferred← citeshttps://doi.org/10.1007/s12253-018-0402-zopenalex-snapshot
Anti-Diabetic Drugs: Cure or Risk Factors for Cancer?
inferred← citeshttps://doi.org/10.1007/s13300-018-0557-3openalex-snapshot
Association Between Metformin and Sulfonylurea Monotherapies and Cancer Incidence: A Real-World Cohort Study in Shanghai, China
inferred← citeshttps://doi.org/10.1016/b978-0-12-820472-6.00098-0openalex-snapshot
Type 2 Diabetes Mellitus
inferred← citeshttps://doi.org/10.1016/b978-0-12-821044-4.00005-4openalex-snapshot
Alternative Models in Biomedical Research: In Silico, In Vitro, Ex Vivo, and Nontraditional In Vivo Approaches
inferred← citeshttps://doi.org/10.1016/j.addr.2021.04.022openalex-snapshot
The chorioallantoic membrane as a bio-barrier model for the evaluation of nanoscale drug delivery systems for tumour therapy
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.153115openalex-snapshot
Targeting myeloid cell leukemia-1 protein to identify potential compounds for chronic myeloid leukemia treatment: Molecular docking and molecular dynamics simulation approaches
inferred← citeshttps://doi.org/10.1016/j.bcp.2016.02.015openalex-snapshot
Poly (ADP-ribose) polymerases inhibitor, Zj6413, as a potential therapeutic agent against breast cancer
inferred← citeshttps://doi.org/10.1016/j.bcp.2020.114052openalex-snapshot
Anti-metastatic effect of midazolam on melanoma B16F10 cells in the lungs of diabetic mice
inferred← citeshttps://doi.org/10.1016/j.ejphar.2019.172598openalex-snapshot
Sulfonylurea derivatives and cancer, friend or foe?
inferred← citeshttps://doi.org/10.1016/j.ejps.2020.105401openalex-snapshot
Understanding Breast cancer: from conventional therapies to repurposed drugs
inferred← citeshttps://doi.org/10.1016/j.jff.2018.07.032openalex-snapshot
Anthocyanins from Hibiscus sabdariffa calyx attenuate in vitro and in vivo melanoma cancer metastasis
inferred← citeshttps://doi.org/10.1016/j.tiv.2021.105128openalex-snapshot
A potential role of calpains in sulfonylureas (SUs) –mediated death of human pancreatic cancer cells (1.2B4)
inferred← citeshttps://doi.org/10.1016/j.yexcr.2015.03.012openalex-snapshot
Glipizide suppresses embryonic vasculogenesis and angiogenesis through targeting natriuretic peptide receptor A
inferred← citeshttps://doi.org/10.1016/j.yexcr.2019.111756openalex-snapshot
R5, a neutralizing antibody to Robo1, suppresses breast cancer growth and metastasis by inhibiting angiogenesis via down-regulating filamin A
inferred← citeshttps://doi.org/10.1021/acsomega.9b04004openalex-snapshot
Solubility Measurement and Various Solubility Parameters of Glipizide in Different Neat Solvents
inferred← citeshttps://doi.org/10.1038/srep27819openalex-snapshot
Glipizide suppresses prostate cancer progression in the TRAMP model by inhibiting angiogenesis
inferred← citeshttps://doi.org/10.1038/srep28139openalex-snapshot
The anti-angiogenic effect and novel mechanisms of action of Combretastatin A-4
inferred← citeshttps://doi.org/10.1039/d2ma00627hopenalex-snapshot
A sustainable nano drug delivery system for poorly soluble drug, glipizide: design, in vitro controlled release and kinetics
inferred← citeshttps://doi.org/10.1039/d5ra00204dopenalex-snapshot
Enhancing diabetes therapy with pH-sensitive co-delivery of metformin hydrochloride and glipizide using MCM-48-based dual drug delivery system
inferred← citeshttps://doi.org/10.1055/a-2237-8566openalex-snapshot
Encyclopaedic Review of Glipizide Pre-clinical and Clinical Status
inferred← citeshttps://doi.org/10.1080/13543784.2017.1333104openalex-snapshot
Enemies or weapons in hands: investigational anti-diabetic drug glibenclamide and cancer risk
inferred← citeshttps://doi.org/10.1080/15384101.2016.1184803openalex-snapshot
Proper autophagy is indispensable for angiogenesis during chick embryo development
inferred← citeshttps://doi.org/10.1111/cbdd.13013openalex-snapshot
New insights into antidiabetic drugs: Possible applications in cancer treatment
inferred← citeshttps://doi.org/10.1155/2018/1251345openalex-snapshot
Glimepiride Administered in Chow Reversibly Impairs Glucose Tolerance in Mice
inferred← citeshttps://doi.org/10.1159/000489979openalex-snapshot
Novel Therapeutic Strategies for Solid Tumor Based on Body’s Intrinsic Antitumor Immune System
inferred← citeshttps://doi.org/10.1371/journal.pone.0196697openalex-snapshot
MicroRNA-425 and microRNA-155 cooperatively regulate atrial natriuretic peptide expression and cGMP production
inferred← citeshttps://doi.org/10.1371/journal.pone.0244293openalex-snapshot
Prognostic roles of diabetes mellitus and hypertension in advanced hepatocellular carcinoma treated with sorafenib
inferred← citeshttps://doi.org/10.18632/oncotarget.3079openalex-snapshot
The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2705322/v1openalex-snapshot
Glipizide alleviates periodontitis pathogenicity via inhibition of angiogenesis, osteoclastogenesis, and M1/M2 macrophage ratio in periodontal tissue
inferred← citeshttps://doi.org/10.2174/1871520621666210910085733openalex-snapshot
Glipizide Combined with ANP Suppresses Breast Cancer Growth and Metastasis by Inhibiting Angiogenesis through VEGF/VEGFR2 Signaling
inferred← citeshttps://doi.org/10.2337/dc15-1358openalex-snapshot
The Use of Glyburide Compared With Other Sulfonylureas and the Risk of Cancer in Patients With Type 2 Diabetes
inferred← citeshttps://doi.org/10.33612/diss.103517830openalex-snapshot
Oral glucose lowering agents and cancer in type 2 diabetes mellitus: focus on sulphonylurea derivatives
inferred← citeshttps://doi.org/10.33612/diss.178801097openalex-snapshot
Glucose metabolism in cancer: heterogeneity and potentials for targeting in patients
inferred← citeshttps://doi.org/10.3389/fphar.2019.00109openalex-snapshot
A Comparative Study of Cluster Detection Algorithms in Protein–Protein Interaction for Drug Target Discovery and Drug Repurposing
inferred← citeshttps://doi.org/10.3389/fphar.2021.728458openalex-snapshot
Sulfonylureas for Treatment of Periodontitis-Diabetes Comorbidity-Related Complications: Killing Two Birds With One Stone
inferred← citeshttps://doi.org/10.3390/app142210469openalex-snapshot
Simultaneous HPLC of Metformin, Glipizide and Gliclazide, and Metformin Uptake and Protection of HEI-OC1 from Hyperglycaemia
inferred← citeshttps://doi.org/10.3390/cancers17071244openalex-snapshot
Can the Tumor Microenvironment Alter Ion Channels? Unraveling Their Role in Cancer
inferred← citeshttps://doi.org/10.3390/ijms221910550openalex-snapshot
β-Caryophyllene Induces Apoptosis and Inhibits Angiogenesis in Colorectal Cancer Models
inferred← citeshttps://doi.org/10.3390/ijms25042129openalex-snapshot
Exploring the Role of Surface and Mitochondrial ATP-Sensitive Potassium Channels in Cancer: From Cellular Functions to Therapeutic Potentials
inferred← citeshttps://doi.org/10.3390/ijms26041429openalex-snapshot
Combining Sulfonylureas with Anticancer Drugs: Evidence of Synergistic Efficacy with Doxorubicin In Vitro and In Vivo
inferred← citeshttps://doi.org/10.54097/hset.v54i.9760openalex-snapshot
Effect of Glipizide on non-insulin-dependent diabetes mellitus
inferred← citeshttps://doi.org/10.54287/gujsa.1281246openalex-snapshot
Investigation of Chloride Anion Binding Properties of Glipizide Drug
inferred← citeshttps://doi.org/10.7150/ijbs.11589openalex-snapshot
P-Selectin-Mediated Adhesion between Platelets and Tumor Cells Promotes Intestinal Tumorigenesis in Apc Min/+ Mice
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