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Significance testing of synergistic/antagonistic, dose level-dependent, or dose ratio-dependent effects in mixture dose-response analysis

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/etc.5620111014openalex-snapshot

A STATISTICAL PROCEDURE FOR MODELING CONTINUOUS TOXICITY DATA

inferredcites →https://doi.org/10.1002/etc.5620150824openalex-snapshot

QUANTITATIVE DESCRIPTION OF MIXTURE TOXICITY: EFFECT OF LEVEL OF RESPONSE ON INTERACTIONS

inferredcites →https://doi.org/10.1002/etc.5620160612openalex-snapshot

Interaction of Cd and Zn toxicity forFolsomia candidaWillem (Collembola: Isotomidae) in relation to bioavailability in soil

inferredcites →https://doi.org/10.1002/etc.5620190926openalex-snapshot

Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri : Mixtures composed of similarly acting chemicals

inferredcites →https://doi.org/10.1002/etc.5620190927openalex-snapshot

Predictability of the toxicity of a multiple mixture of dissimilarly acting chemicals to Vibrio fischeri

inferredcites →https://doi.org/10.1002/etc.5620191208openalex-snapshot

Mixture toxicity of copper and diazinon to larvae of the mayfly (Ephoron virgo) judging additivity at different effect levels

inferredcites →https://doi.org/10.1002/etc.5620220719openalex-snapshot

Joint acute toxicity of diazinon and copper toCeriodaphnia dubia

inferredcites →https://doi.org/10.1002/tox.2530100204openalex-snapshot

Toxicity of binary mixtures of organic chemicals

inferredcites →https://doi.org/10.1006/eesa.1997.1568openalex-snapshot

Single and Joint Toxic Effects of Copper and Zinc on Reproduction ofEnchytraeus crypticusin Relation to Sorption of Metals in Soils

inferredcites →https://doi.org/10.1006/eesa.2002.2155openalex-snapshot

Mixture Toxicity of Zinc, Cadmium, Copper, and Lead to the Potworm Enchytraeus albidus

inferredcites →https://doi.org/10.1007/978-94-011-1344-1_6openalex-snapshot

Cadmium

inferredcites →https://doi.org/10.1007/bf02143194openalex-snapshot

The use of sigmoidal dose response curves in soil ecotoxicological research

inferredcites →https://doi.org/10.1016/0043-1354(70)90018-7openalex-snapshot

Measurement of pollutant toxicity to fish. II. Utilizing and applying bioassay results

inferredcites →https://doi.org/10.1016/0043-1354(84)90071-xopenalex-snapshot

Dose-response functions in aquatic toxicity testing and the Weibull model

inferredcites →https://doi.org/10.1016/0166-445x(87)90029-4openalex-snapshot

Simple similar action and independent joint action - two similar models for the joint effects of toxicants applied as mixtures

inferredcites →https://doi.org/10.1016/b978-0-12-768350-8.50030-xopenalex-snapshot

Analysis of Chemical Combinations: Relating Isobolograms to Response Surfaces

inferredcites →https://doi.org/10.1016/j.etap.2003.10.004openalex-snapshot

Mechanistic approaches for mixture risk assessments—present capabilities with simple mixtures and future directions

inferredcites →https://doi.org/10.1016/s0022-5193(85)80176-4openalex-snapshot

The expected effect of a combination of agents: the general solution

inferredcites →https://doi.org/10.1016/s0031-6997(25)06847-4openalex-snapshot

The search for synergy: a critical review from a response surface perspective.

inferredcites →https://doi.org/10.1016/s0045-6535(97)10228-4openalex-snapshot

Mixture toxicity and tissue interactions of Cd, Cu, Pb and Zn in earthworms (Oligochaeta) in laboratory and field soils: A critical evaluation of data

inferredcites →https://doi.org/10.1016/s0048-9697(01)01113-5openalex-snapshot

Synergy and other ineffective mixture risk definitions

inferredcites →https://doi.org/10.1016/s0048-9697(05)80100-7openalex-snapshot

Combined effects of toxicants: the need and soundness of assessment approaches in ecotoxicology

inferredcites →https://doi.org/10.1016/s0048-9697(99)00228-4openalex-snapshot

Approaches to assessing combination effects of oestrogenic environmental pollutants

inferredcites →https://doi.org/10.1016/s0166-445x(99)00069-7openalex-snapshot

The single substance and mixture toxicity of quinolones to the bioluminescent bacterium Vibrio fischeri

inferredcites →https://doi.org/10.1016/s0300-483x(00)00196-7openalex-snapshot

Comparative evaluation of the combined osteolathyritic effects of two nitrile combinations on Xenopus embryos

inferredcites →https://doi.org/10.1021/es0101227openalex-snapshot

Something from “Nothing” − Eight Weak Estrogenic Chemicals Combined at Concentrations below NOECs Produce Significant Mixture Effects

inferredcites →https://doi.org/10.1080/00031305.1995.10476112openalex-snapshot

Teaching about Approximate Confidence Regions Based on Maximum Likelihood Estimation

inferredcites →https://doi.org/10.1080/00401706.1997.10485141openalex-snapshot

Applied Linear Statistical Models

inferredcites →https://doi.org/10.1093/toxsci/63.1.132openalex-snapshot

Toxicological Interactions among Arsenic, Cadmium, Chromium, and Lead in Human Keratinocytes

inferredcites →https://doi.org/10.1111/j.1539-6924.1994.tb00081.xopenalex-snapshot

Dose‐Response Analysis Using Spreadsheets

inferredcites →https://doi.org/10.1111/j.1744-7348.1939.tb06990.xopenalex-snapshot

THE TOXICITY OF POISONS APPLIED JOINTLY1

inferredcites →https://doi.org/10.1111/j.1744-7348.1950.tb00973.xopenalex-snapshot

STATISTICAL ASPECTS OF THE INDEPENDENT JOINT ACTION OF POISONS, PARTICULARLY INSECTICIDES

inferredcites →https://doi.org/10.1155/1994/101740openalex-snapshot

Monte Carlo Comparison of Rival Experimental Designs For Two‐Agent Combined Action Studies

inferredcites →https://doi.org/10.1198/108571102317475062openalex-snapshot

Statistical analysis of interactive cytotoxicity in human epidermal keratinocytes following exposure to a mixture of four metals

inferredcites →https://doi.org/10.1289/ehp.00108983openalex-snapshot

Prediction and Assessment of the Effects of Mixtures of Four Xenoestrogens

inferredcites →https://doi.org/10.1897/1551-5028(1997)016<1177:iocazt>2.3.co;2openalex-snapshot

INTERACTION OF Cd AND Zn TOXICITY FOR FOLSOMIA CANDIDA WILLEM (COLLEMBOLA: ISOTOMIDAE) IN RELATION TO BIOAVAILABILITY IN SOIL

inferredcites →https://doi.org/10.1897/1551-5028(2000)019<2341:pottom>2.3.co;2openalex-snapshot

PREDICTABILITY OF THE TOXICITY OF MULTIPLE CHEMICAL MIXTURES TO VIBRIO FISCHERI: MIXTURES COMPOSED OF SIMILARLY ACTING CHEMICALS

inferredcites →https://doi.org/10.1897/1551-5028(2000)019<2900:mtocad>2.0.co;2openalex-snapshot

MIXTURE TOXICITY OF COPPER AND DIAZINON TO LARVAE OF THE MAYFLY (EPHORON VIRGO) JUDGING ADDITIVITY AT DIFFERENT EFFECT LEVELS

inferredcites →https://doi.org/10.2307/2527657openalex-snapshot

A Unified Theory for Quantal Responses to Mixtures of Drugs: Non-Interactive Action

inferredcites →https://doi.org/10.2307/2531291openalex-snapshot

A General Noninteractive Multiple Toxicity Model Including Probit, Logit, and Weibull Transformations

inferredcites →https://doi.org/10.2307/2684811openalex-snapshot

Teaching about Approximate Confidence Regions Based on Maximum Likelihood Estimation

inferredcites →https://doi.org/10.2307/3802723openalex-snapshot

Model Selection and Multimodel Inference: A Practical Information-Theoretic Approach

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Warming Influence on the Toxicity of a Binary Mixture of Pesticides to the Zooplankton Species Artemia Franciscana

inferred← citeshttps://doi.org/10.1002/9780470061596.risk0287openalex-snapshot

Statistics for Environmental Toxicity

inferred← citeshttps://doi.org/10.1002/9781118445112.stat03795openalex-snapshot

Environmental Toxicology, Statistics in

inferred← citeshttps://doi.org/10.1002/9781118445112.stat03795.pub2openalex-snapshot

Environmental Toxicology, Statistics in

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A Toxicological Application of Signal Transduction

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Contamination and genotoxicity biomarker responses in bivalve mussels from the major Lithuanian rivers

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Similarity, independence, or interaction for binary mixture effects of nerve toxicants for the nematode Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1002/etc.198openalex-snapshot

Toxicity of three binary mixtures to Daphnia magna: Comparing chemical modes of action and deviations from conceptual models

inferred← citeshttps://doi.org/10.1002/etc.2296openalex-snapshot

Combined exposure to cyanobacteria and carbaryl results in antagonistic effects on the reproduction of daphnia pulex

inferred← citeshttps://doi.org/10.1002/etc.2780openalex-snapshot

Testing an application of a biotic ligand model to predict acute toxicity of metal mixtures to rainbow trout

inferred← citeshttps://doi.org/10.1002/etc.2792openalex-snapshot

Metal Mixtures Modeling Evaluation project: 1. Background

inferred← citeshttps://doi.org/10.1002/etc.2802openalex-snapshot

Interaction between nickel and cobalt toxicity inEnchytraeus crypticusis due to competitive uptake

inferred← citeshttps://doi.org/10.1002/etc.2862openalex-snapshot

Application of a generalized linear mixed model to analyze mixture toxicity: Survival of brown trout affected by copper and zinc

inferred← citeshttps://doi.org/10.1002/etc.2902openalex-snapshot

Mixture toxicity of nickel and zinc toDaphnia magnais noninteractive at low effect sizes but becomes synergistic at high effect sizes

inferred← citeshttps://doi.org/10.1002/etc.2971openalex-snapshot

Responses of wheat (Triticum aestivum) and turnip (Brassica rapa) to the combined exposure of carbaryl and ultraviolet radiation

inferred← citeshttps://doi.org/10.1002/etc.3147openalex-snapshot

Complex mixtures, complex responses: Assessing pharmaceutical mixtures using field and laboratory approaches

inferred← citeshttps://doi.org/10.1002/etc.3204openalex-snapshot

Acute toxicity of binary-metal mixtures of copper, zinc, and nickel toPimephales promelas: Evidence of more-than-additive effect

inferred← citeshttps://doi.org/10.1002/etc.3208openalex-snapshot

Co-exposure of ZnO nanoparticles and UV radiation toDaphnia magnaandDanio rerio: Combined effects rather than protection

inferred← citeshttps://doi.org/10.1002/etc.3235openalex-snapshot

Temperature and food concentration have limited influence on the mixture toxicity of copper and Microcystis aeruginosa to Daphnia magna

inferred← citeshttps://doi.org/10.1002/etc.3263openalex-snapshot

Concentration addition and response addition to analyze mixture toxicity: Is it worth testing?

inferred← citeshttps://doi.org/10.1002/etc.3332openalex-snapshot

Reproductive toxicity of binary and ternary mixture combinations of nickel, zinc, and lead to Ceriodaphnia dubia is best predicted with the independent action model

inferred← citeshttps://doi.org/10.1002/etc.3334openalex-snapshot

Criteria for deviation from predictions by the concentration addition model

inferred← citeshttps://doi.org/10.1002/etc.3380openalex-snapshot

Mixture toxicity and interactions of copper, nickel, cadmium, and zinc to barley at low effect levels: Something from nothing?

inferred← citeshttps://doi.org/10.1002/etc.3445openalex-snapshot

The effect of binary mixtures of zinc, copper, cadmium, and nickel on the growth of the freshwater diatom Navicula pelliculosa and comparison with mixture toxicity model predictions

inferred← citeshttps://doi.org/10.1002/etc.3503openalex-snapshot

Generalized concentration addition approach for predicting mixture toxicity

inferred← citeshttps://doi.org/10.1002/etc.3529openalex-snapshot

Mixture toxicity of copper, cadmium, and zinc to barley seedlings is not explained by antioxidant and oxidative stress biomarkers

inferred← citeshttps://doi.org/10.1002/etc.3628openalex-snapshot

Comparison of chronic mixture toxicity of nickel-zinc-copper and nickel-zinc-copper-cadmium mixtures betweenCeriodaphnia dubiaandPseudokirchneriella subcapitata

inferred← citeshttps://doi.org/10.1002/etc.3674openalex-snapshot

Additive toxicity of zinc and arsenate on barley (Hordeum vulgare) root elongation

inferred← citeshttps://doi.org/10.1002/etc.3878openalex-snapshot

Cumulative toxicity of neonicotinoid insecticide mixtures to Chironomus dilutus under acute exposure scenarios

inferred← citeshttps://doi.org/10.1002/etc.3913openalex-snapshot

Mixture toxicity in the marine environment: Model development and evidence for synergism at environmental concentrations

inferred← citeshttps://doi.org/10.1002/etc.3999openalex-snapshot

Mixtures of Cu, Ni, and Zn act mostly noninteractively onPseudokirchneriella subcapitatagrowth in natural waters

inferred← citeshttps://doi.org/10.1002/etc.4039openalex-snapshot

A framework for ecological risk assessment of metal mixtures in aquatic systems

inferred← citeshttps://doi.org/10.1002/etc.4164openalex-snapshot

Petroleum hydrocarbon mixture toxicity and a trait-based approach to soil invertebrate species for site-specific risk assessments

inferred← citeshttps://doi.org/10.1002/etc.4386openalex-snapshot

Acute Effects of Binary Mixtures of Imidacloprid and Tebuconazole on 4 Freshwater Invertebrates

inferred← citeshttps://doi.org/10.1002/etc.4399openalex-snapshot

Diffusive Gradients in Thin Films Can Predict the Toxicity of Metal Mixtures to Two Microalgae: Validation for Environmental Monitoring in Antarctic Marine Conditions

inferred← citeshttps://doi.org/10.1002/etc.4563openalex-snapshot

Validation of Bioavailability-Based Toxicity Models for Metals

inferred← citeshttps://doi.org/10.1002/etc.4889openalex-snapshot

Fire Suppression Agents Combined with Gasoline in Aquatic Ecosystems: A Mixture Approach

inferred← citeshttps://doi.org/10.1002/etc.499openalex-snapshot

Response predictions for organisms water-exposed to metal mixtures: A meta-analysis

inferred← citeshttps://doi.org/10.1002/etc.5034openalex-snapshot

Correlated Ni, Cu, and Zn Sensitivities of 8 Freshwater Algal Species and Consequences for Low-Level Metal Mixture Effects

inferred← citeshttps://doi.org/10.1002/etc.5038openalex-snapshot

Effect of Dissolved Organic Matter Concentration and Source on the Chronic Toxicity of Copper and Nickel Mixtures to Chlorella sp.

inferred← citeshttps://doi.org/10.1002/etc.5162openalex-snapshot

Toxicity and Risk Assessment of Zinc and Aluminum Mixtures to Ceriodaphnia silvestrii (Crustacea: Cladocera)

inferred← citeshttps://doi.org/10.1002/etc.5176openalex-snapshot

Interactive Metal Mixture Toxicity to Daphnia magna Populations as an Emergent Property in a Dynamic Energy Budget Individual-Based Model

inferred← citeshttps://doi.org/10.1002/etc.5285openalex-snapshot

Individual and Combined Effects of Manganese and Chromium on a Freshwater Chlorophyceae

inferred← citeshttps://doi.org/10.1002/etc.5401openalex-snapshot

Mixture Toxicity of Herbicides with Dissimilar Modes of Action to Myriophyllum spicatum

inferred← citeshttps://doi.org/10.1002/etc.5735openalex-snapshot

Metal Mixture Toxicity of Ni, Cu, and Zn in Freshwater Algal Communities and the Correlation of Single-Species Sensitivities Among Single Metals: A Comparative Analysis

inferred← citeshttps://doi.org/10.1002/etc.5927openalex-snapshot

Effects of Cadmium and Nickel Mixtures on Multiple Endpoints of the Microalga Raphidocelis subcapitata

inferred← citeshttps://doi.org/10.1002/etc.595openalex-snapshot

Interactions of cadmium and zinc impact their toxicity to the earthworm Aporrectodea caliginosa

inferred← citeshttps://doi.org/10.1002/etc.5970openalex-snapshot

Metal Mixture Effects of Ni, Cu, and Zn in a Multispecies, Two-Trophic–Level Algal–Daphnid Microcosm Can Be Predicted From Single-Trophic–Level Effects: The Role of Indirect Toxicity

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Embryo development, stress protein (Hsp70) responses, and histopathology in zebrafish (Danio rerio) following exposure to nickel chloride, chlorpyrifos, and binary mixtures of them

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Ecotoxicological effects of Mikado® and Viper® on algae and daphnids

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Cadmium and chlorpyrifos inhibit cellular immune response in spleen of rats

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Toxicity interactions of azole fungicide mixtures on Chlorella pyrenoidosa

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Important Issues in Ecotoxicological Investigations Using Earthworms

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Comparative Study of Risk Assessment Approaches Based on Different Methods for Deriving DNEL and PNEC of Chemical Mixtures

inferred← citeshttps://doi.org/10.1007/978-94-007-4470-7_5openalex-snapshot

Effects of Heavy Metals and Metalloids on Soil Organisms

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Evaluating Impacts of Multiple Stressors on Aquatic Ecosystems Using Isobolic Models

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Contaminant Mixtures and Reproduction in Aquatic Organisms

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Toxicity of Diclofenac: Cadmium Binary Mixtures to Algae Desmodesmus subspicatus Using Normalization Method

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Toxicity of Binary Metal Mixtures to the Tropical Ostracod Strandesia Trispinosa

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Influence of Nickel Chloride, Chlorpyrifos, and Imidacloprid in Combination with Different Temperatures on the Embryogenesis of the Zebrafish Danio rerio

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Single Versus Combined Lethal Effects of Three Agricultural Insecticides on Larvae of the Freshwater Insect Chironomus dilutus

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Impact of Suspended Solids on the Use of LuminoTox to Detect Toxicity of Micropollutants

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The Effects of Combinatorial Treatments With Stress Inducing Molecules on Growth of E. coli Colonies

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Organophosphorous insecticides as herbicide synergists on the green algae Pseudokirchneriella subcapitata and the aquatic plant Lemna minor

inferred← citeshttps://doi.org/10.1007/s10646-008-0291-0openalex-snapshot

Effects of 3,4-dichloroaniline and diazinon on different biological organisation levels of zebrafish (Danio rerio) embryos and larvae

inferred← citeshttps://doi.org/10.1007/s10646-009-0417-zopenalex-snapshot

A biology-based approach for mixture toxicity of multiple endpoints over the life cycle

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Cadmium, lead and their mixtures with copper: Paracentrotus lividus embryotoxicity assessment, prediction, and offspring quality evaluation

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Growth rate of Pseudokirchneriella subcapitata exposed to herbicides found in surface waters in the Alqueva reservoir (Portugal): a bottom-up approach using binary mixtures

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Transcriptional responses indicate attenuated oxidative stress in the springtail Folsomia candida exposed to mixtures of cadmium and phenanthrene

inferred← citeshttps://doi.org/10.1007/s10646-014-1347-yopenalex-snapshot

Prediction of the joint toxicity of five organophosphorus pesticides to Daphnia magna

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The use of growth and behavioral endpoints to assess the effects of pesticide mixtures upon aquatic organisms

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Ecotoxicological evaluation of propranolol hydrochloride and losartan potassium to Lemna minor L. (1753) individually and in binary mixtures

inferred← citeshttps://doi.org/10.1007/s10646-016-1633-yopenalex-snapshot

The interactive effects of microcystin-LR and cylindrospermopsin on the growth rate of the freshwater algae Chlorella vulgaris

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Assessing the environmental hazard of individual and combined pharmaceuticals: acute and chronic toxicity of fluoxetine and propranolol in the crustacean Daphnia magna

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Sensitivities of three tropical indigenous freshwater invertebrates to single and mixture exposures of diuron and carbofuran and their commercial formulations

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Toxicity prediction and assessment of an environmentally realistic pesticide mixture to Daphnia magna and Raphidocelis subcapitata

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Ecotoxicological assessment of the herbicide Winner Top and its active substances—are the other formulants truly inert?

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Freshwater neotropical oligochaetes as native test species for the toxicity evaluation of cadmium, mercury and their mixtures

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Comparative ecotoxicity of single and binary mixtures exposures of nickel and zinc on growth and biomarkers of Lemna gibba

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Comparative ecotoxicity of single and binary mixtures exposures of cadmium and zinc on growth and biomarkers of Lemna gibba

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Toxicity of binary mixtures of Cu, Cr and As to the earthworm Eisenia andrei

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Acute and chronic toxicity of 2,4-D and fipronil formulations (individually and in mixture) to the Neotropical cladoceran Ceriodaphnia silvestrii

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Comparative ecotoxicity of single and binary mixtures exposures of cadmium and nickel on growth and biomarkers of Lemna gibba

inferred← citeshttps://doi.org/10.1007/s10646-022-02574-yopenalex-snapshot

Toxicity of lanthanides on various fish cell lines

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Recommended rates of azoxystrobin and tebuconazole seem to be environmentally safe but ineffective against target fungi

inferred← citeshttps://doi.org/10.1007/s10646-024-02728-0openalex-snapshot

Isolated and combined effects of cobalt and nickel on the microalga Raphidocelis subcapitata

inferred← citeshttps://doi.org/10.1007/s10646-024-02761-zopenalex-snapshot

Effects of acute toxicity of the pesticide Chlorpyrifos and the metal Cadmium, both individually and in mixtures, on two species of native neotropical cladocerans

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Combined effects of a pyrethroid insecticide and azole fungicide on lepidopteran growth analysed with DEB-TKTD modelling

inferred← citeshttps://doi.org/10.1007/s10653-023-01491-1openalex-snapshot

New insights into the effects of antibiotics and copper on microbial community diversity and carbon source utilization

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Effects of dichlorobenzene, toluene, benzene and formaldehyde chemicals on Drosophila melanogaster mortality

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Effects of copper and cadmium mixtures on photosynthetic parameters of the freshwater microalga Ankistrodesmus densus (Chlorophyceae)

inferred← citeshttps://doi.org/10.1007/s11270-012-1335-xopenalex-snapshot

Ecotoxicological Assessment of Contaminated River Sites as a Proxy for the Water Framework Directive: an Acid Mine Drainage Case Study

inferred← citeshttps://doi.org/10.1007/s11356-010-0298-yopenalex-snapshot

The influence of natural stressors on the toxicity of nickel to Daphnia magna

inferred← citeshttps://doi.org/10.1007/s11356-012-1443-6openalex-snapshot

Synergistic effects caused by atrazine and terbuthylazine on chlorpyrifos toxicity to early-life stages of the zebrafish Danio rerio

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Brain glutathione redox system significance for the control of silica-coated magnetite nanoparticles with or without mercury co-exposures mediated oxidative stress in European eel (Anguilla anguilla L.)

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Combined effect of Cd and Pb spiked field soils on bioaccumulation, DNA damage, and peroxidase activities in Trifolium repens

inferred← citeshttps://doi.org/10.1007/s11356-016-6492-9openalex-snapshot

Reproductive and developmental toxicity of the herbicide Betanal® Expert and corresponding active ingredients to Daphnia spp.

inferred← citeshttps://doi.org/10.1007/s11356-018-1752-5openalex-snapshot

Toxicity interactions between manganese (Mn) and lead (Pb) or cadmium (Cd) in a model organism the nematode C. elegans

inferred← citeshttps://doi.org/10.1007/s11356-018-1909-2openalex-snapshot

Combined acute ecotoxicity of malathion and deltamethrin to Daphnia magna (Crustacea, Cladocera): comparison of different data analysis approaches

inferred← citeshttps://doi.org/10.1007/s11356-018-2302-xopenalex-snapshot

Ecotoxicological and biochemical mixture effects of an herbicide and a metal at the marine primary producer diatom Thalassiosira weissflogii and the primary consumer copepod Acartia tonsa

inferred← citeshttps://doi.org/10.1007/s11356-019-05040-1openalex-snapshot

Long-term exposure of Daphnia magna to carbendazim: how it affects toxicity to another chemical or mixture

inferred← citeshttps://doi.org/10.1007/s11356-019-07322-0openalex-snapshot

Assessment of the ecotoxicity of the pharmaceuticals bisoprolol, sotalol, and ranitidine using standard and behavioral endpoints

inferred← citeshttps://doi.org/10.1007/s11356-021-13296-9openalex-snapshot

Toxicity of fipronil and 2,4-D formulations (alone and in a mixture) to the tropical amphipod Hyalella meinerti

inferred← citeshttps://doi.org/10.1007/s11356-022-19111-3openalex-snapshot

A critical review of effect modeling for ecological risk assessment of plant protection products

inferred← citeshttps://doi.org/10.1007/s11356-023-26847-zopenalex-snapshot

Toxicity of fipronil and 2,4-D pesticides in Daphnia similis: a multiple endpoint approach

inferred← citeshttps://doi.org/10.1007/s11356-023-28066-yopenalex-snapshot

The acute effects of fipronil and 2,4-D, individually and in mixture: a threat to the freshwater Calanoida copepod Notodiaptomus iheringi

inferred← citeshttps://doi.org/10.1007/s11368-010-0195-5openalex-snapshot

Can mouth part deformities of Chironomus riparius serve as indicators for water and sediment pollution? A laboratory approach

inferred← citeshttps://doi.org/10.1007/s11368-011-0393-9openalex-snapshot

Joint toxicity of three plant protection products to Triticum aestivum (L.) and Brassica rapa (L.)

inferred← citeshttps://doi.org/10.1007/s11368-014-0892-6openalex-snapshot

Short-term exposure to carbaryl and UV radiation increases the reproduction output of the collembolan Folsomia candida

inferred← citeshttps://doi.org/10.1007/s11434-015-0925-6openalex-snapshot

Uniform design ray in the assessment of combined toxicities of multi-component mixtures

inferred← citeshttps://doi.org/10.1007/s11705-016-1574-2openalex-snapshot

Curcumin based combination therapy for anti-breast cancer: from in vitro drug screening to in vivo efficacy evaluation

inferred← citeshttps://doi.org/10.1007/s11783-017-0916-8openalex-snapshot

Toxicity models of metal mixtures established on the basis of “additivity” and “interactions”

inferred← citeshttps://doi.org/10.1007/s12571-023-01346-8openalex-snapshot

Global honeybee health decline factors and potential conservation techniques

inferred← citeshttps://doi.org/10.1007/s13253-010-0041-7openalex-snapshot

A Random Effects Model for Binary Mixture Toxicity Experiments

inferred← citeshttps://doi.org/10.1007/s40203-023-00168-yopenalex-snapshot

A mechanistic assessment of the nature of pharmacodynamic drug-drug interaction in vivo and in vitro

inferred← citeshttps://doi.org/10.1007/s41742-022-00433-6openalex-snapshot

The Ecotoxicity of Sugarcane Pesticides to Non-target Soil Organisms as a Function of Soil Properties and Moisture Conditions

inferred← citeshttps://doi.org/10.1016/b978-0-12-811063-8.00007-0openalex-snapshot

Environmental Toxicity Assessment of Complex Inorganic Materials

inferred← citeshttps://doi.org/10.1016/b978-0-443-23560-3.00027-9openalex-snapshot

Studies on the combined effects of heavy metals and pesticides on earthworms using models and indices

inferred← citeshttps://doi.org/10.1016/j.apsoil.2008.11.006openalex-snapshot

The combined stress effects of salinity and copper on the earthworm Eisenia fetida

inferred← citeshttps://doi.org/10.1016/j.apsoil.2009.11.006openalex-snapshot

Effects of natural (flooding and drought) and anthropogenic (copper and salinity) stressors on the earthworm Aporrectodea caliginosa under field conditions

inferred← citeshttps://doi.org/10.1016/j.apsoil.2011.04.009openalex-snapshot

Evaluation of the combined effects of dimethoate and spirodiclofen on plants and earthworms in a designed microcosm experiment

inferred← citeshttps://doi.org/10.1016/j.apsoil.2014.08.007openalex-snapshot

Single and mixture toxicity of gold nanoparticles and gold(III) to Enchytraeus buchholzi (Oligochaeta)

inferred← citeshttps://doi.org/10.1016/j.apsoil.2022.104526openalex-snapshot

Screening the habitat function of biochar-amended vineyard soils at field plot-scale, based on invertebrate avoidance behaviour

inferred← citeshttps://doi.org/10.1016/j.aquatox.2007.03.025openalex-snapshot

Comparison of nickel toxicity to cladocerans in soft versus hard surface waters

inferred← citeshttps://doi.org/10.1016/j.aquatox.2007.12.013openalex-snapshot

Temperature-dependent effects of the pesticides thiacloprid and diazinon on the embryonic development of zebrafish (Danio rerio)

inferred← citeshttps://doi.org/10.1016/j.aquatox.2008.05.012openalex-snapshot

Toxicity prediction of binary combinations of cadmium, carbendazim and low dissolved oxygen on Daphnia magna

inferred← citeshttps://doi.org/10.1016/j.aquatox.2009.04.008openalex-snapshot

Fear and loathing in the benthos: Responses of aquatic insect larvae to the pesticide imidacloprid in the presence of chemical signals of predation risk

inferred← citeshttps://doi.org/10.1016/j.aquatox.2010.07.017openalex-snapshot

Transcriptomic signatures in Chlamydomonas reinhardtii as Cd biomarkers in metal mixtures

inferred← citeshttps://doi.org/10.1016/j.aquatox.2011.01.007openalex-snapshot

Is ultraviolet radiation a synergistic stressor in combined exposures? The case study of Daphnia magna exposure to UV and carbendazim

inferred← citeshttps://doi.org/10.1016/j.aquatox.2012.02.030openalex-snapshot

The use of multiple endpoints to assess cellular responses to environmental contaminants in the interstitial marine ciliate Euplotes crassus

inferred← citeshttps://doi.org/10.1016/j.aquatox.2013.06.003openalex-snapshot

Structure–activity relationship of non-coplanar polychlorinated biphenyls toward skeletal muscle ryanodine receptors in rainbow trout (Oncorhynchus mykiss)

inferred← citeshttps://doi.org/10.1016/j.aquatox.2013.07.005openalex-snapshot

An investigation of the inter-clonal variation of the interactive effects of cadmium and Microcystis aeruginosa on the reproductive performance of Daphnia magna

inferred← citeshttps://doi.org/10.1016/j.aquatox.2017.02.001openalex-snapshot

Toxicity of abamectin and difenoconazole mixtures to a Neotropical cladoceran after simulated run-off and spray drift exposure

inferred← citeshttps://doi.org/10.1016/j.aquatox.2018.04.021openalex-snapshot

Combined effects of metal mixtures and predator stress on the freshwater isopod Asellus aquaticus

inferred← citeshttps://doi.org/10.1016/j.aquatox.2019.03.015openalex-snapshot

Toxicity of binary mixtures of pesticides to the marine microalgae Tisochrysis lutea and Skeletonema marinoi: Substance interactions and physiological impacts

inferred← citeshttps://doi.org/10.1016/j.aquatox.2019.04.008openalex-snapshot

Joint effects of gamma radiation and cadmium on subcellular-, individual- and population-level endpoints of the green microalga Raphidocelis subcapitata

inferred← citeshttps://doi.org/10.1016/j.aquatox.2020.105712openalex-snapshot

Functional responses of Hyalella meinerti after exposure to environmentally realistic concentrations of 2,4-D, fipronil, and vinasse (individually and in mixture)

inferred← citeshttps://doi.org/10.1016/j.aquatox.2022.106077openalex-snapshot

Effects of cadmium and cobalt mixtures on growth and photosynthesis of Raphidocelis subcapitata (Chlorophyceae)

inferred← citeshttps://doi.org/10.1016/j.aquatox.2025.107606openalex-snapshot

Ecological risks of imidacloprid and tebuconazole in tropical freshwater invertebrates: Single and mixture implications

inferred← citeshttps://doi.org/10.1016/j.aquatox.2026.107741openalex-snapshot

Zooplankton are adversely affected by chronic exposure to Raphidiopsis raciborskii (Cyanobacteria) and acetamiprid: A study of single and combined toxicity

inferred← citeshttps://doi.org/10.1016/j.buildenv.2025.112619openalex-snapshot

Safe or unsafe: Role of exposure time and interactions between volatile organic compounds in mixtures

inferred← citeshttps://doi.org/10.1016/j.cbpc.2008.05.003openalex-snapshot

Exposure to mercury reduces cold tolerance in the springtail Folsomia candida

inferred← citeshttps://doi.org/10.1016/j.cbpc.2024.110067openalex-snapshot

Pitfalls in measuring solution toxicity using the level of bioluminescence inhibition in Aliivibrio fischeri

inferred← citeshttps://doi.org/10.1016/j.chemolab.2019.02.003openalex-snapshot

Comparing D-optimal designs with common mixture experimental designs for logistic regression

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2009.03.027openalex-snapshot

Non-simultaneous ecotoxicity testing of single chemicals and their mixture results in erroneous conclusions about the joint action of the mixture

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2009.10.066openalex-snapshot

Pesticide exposure and inducible antipredator responses in the zooplankton grazer, Daphnia magna Straus

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2010.02.032openalex-snapshot

Mixture effects of nickel and chlorpyrifos on Folsomia candida (Collembola) explained from development of toxicity in time

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2010.05.031openalex-snapshot

Joint effects of three plant protection products to the terrestrial isopod Porcellionides pruinosus and the collembolan Folsomia candida

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2010.10.063openalex-snapshot

Evaluation on the toxicity of ionic liquid mixture with antagonism and synergism to Vibrio qinghaiensis sp.-Q67

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2012.03.043openalex-snapshot

Influence factors of multicomponent mixtures containing reactive chemicals and their joint effects

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2013.07.012openalex-snapshot

Alleviating CTAC and Flu combined pollution damage in Chlorella vulgaris by exogenous nitric oxide

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2013.12.023openalex-snapshot

Comparative and combined acute toxicity of butachlor, imidacloprid and chlorpyrifos on earthworm, Eisenia fetida

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2015.10.034openalex-snapshot

Toxicity interaction between chlorpyrifos, mancozeb and soil moisture to the terrestrial isopod Porcellionides pruinosus

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2015.11.064openalex-snapshot

Toxicity of seabird guano to sea urchin embryos and interaction with Cu and Pb

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2015.12.029openalex-snapshot

Dynamic energy-based modeling of uranium and cadmium joint toxicity to Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2016.05.050openalex-snapshot

Combined cytotoxic effects of pesticide mixtures present in the Chinese diet on human hepatocarcinoma cell line

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2017.04.146openalex-snapshot

Acute mixture toxicity of halogenated chemicals and their next generation counterparts on zebrafish embryos

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2017.09.027openalex-snapshot

Single and mixture toxicity of abamectin and difenoconazole to adult zebrafish (Danio rerio)

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2017.12.049openalex-snapshot

LuminoTox as a tool to optimize ozone doses for the removal of contaminants and their associated toxicity

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2018.06.139openalex-snapshot

Combined effects of antifouling biocides on the growth of three marine microalgal species

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2018.07.027openalex-snapshot

Lethal and sublethal toxicity of abamectin and difenoconazole (individually and in mixture) to early life stages of zebrafish

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2018.08.153openalex-snapshot

Unraveling the ecotoxicity of deep eutectic solvents using the mixture toxicity theory

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2019.03.104openalex-snapshot

Combined toxicities of tributyltin and polychlorinated biphenyls on the development and hatching of Japanese medaka (Oryzias latipes) embryos via in ovo nanoinjection

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2019.05.213openalex-snapshot

Toxicity assessment of metal mixtures to soil enzymes is influenced by metal dosing method

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2019.06.200openalex-snapshot

Single and mixture toxicity of four pharmaceuticals of environmental concern to aquatic organisms, including a behavioral assessment

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2019.125231openalex-snapshot

Zinc and aluminum mixtures have synergic effects to the algae Raphidocelis subcapitata at environmental concentrations

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2020.126433openalex-snapshot

Effects of glyphosate, cypermethrin, and chlorpyrifos on hematological parameters of the tegu lizard (Salvator merianae) in different embryo stages

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2021.133432openalex-snapshot

Mixture toxicity prediction of substances from different origin sources in Daphnia magna

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2022.136671openalex-snapshot

Acute and chronic ecotoxicological effects of pharmaceuticals and their mixtures in Daphnia similis

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2025.144791openalex-snapshot

Evaluating the acute toxicity of binary and ternary mixtures of Cu, Zn, As and Se to Daphnia magna: a component-based approach using isobologram analyses and ternary diagrams

inferred← citeshttps://doi.org/10.1016/j.cnd.2012.03.002openalex-snapshot

Les polluants organiques persistants : implication dans l’obésité et le syndrome métabolique

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2006.12.006openalex-snapshot

Is mixture toxicity measured on a biomarker indicative of what happens on a population level? A study with Lemna minor

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2008.03.002openalex-snapshot

Synergistic interaction between 4-nonylphenol and high but not low temperatures in Dendrobaena octaedra

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2008.07.006openalex-snapshot

Measuring and modelling mixture toxicity of imidacloprid and thiacloprid on Caenorhabditis elegans and Eisenia fetida

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2008.09.003openalex-snapshot

A model to analyze effects of complex mixtures on survival

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2009.04.014openalex-snapshot

Behavioural and developmental toxicity of chlorpyrifos and nickel chloride to zebrafish (Danio rerio) embryos and larvae

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2010.07.010openalex-snapshot

Effects of binary mixtures on the life traits of Daphnia magna

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2011.01.007openalex-snapshot

Predicting mixture toxicity of seven phenolic compounds with similar and dissimilar action mechanisms to Vibrio qinghaiensis sp.nov.Q67

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2011.06.003openalex-snapshot

Evaluation of the joint effect of glyphosate and dimethoate using a small-scale terrestrial ecosystem

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2012.09.022openalex-snapshot

Enzymatic biomarkers of earthworms Eisenia fetida in response to individual and combined cadmium and pyrene

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2013.05.018openalex-snapshot

Combined toxicity of pesticide mixtures on green algae and photobacteria

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2014.02.024openalex-snapshot

Identifying the component responsible for antagonism within ionic liquid mixtures using the up-to-down procedure integrated with a uniform design ray method

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2014.04.004openalex-snapshot

Carbaryl toxicity prediction to soil organisms under high and low temperature regimes

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2014.07.039openalex-snapshot

Changes of chemical chronic toxicity to Daphnia magna under different food regimes

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2014.10.015openalex-snapshot

Toxicity of mixtures of λ-cyhalothrin, imidacloprid and cadmium on the earthworm Eisenia fetida by combination index (CI)-isobologram method

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2015.02.008openalex-snapshot

10-Day survival of Hyalella azteca as a function of water quality parameters

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2015.02.022openalex-snapshot

Ecotoxicity and genotoxicity of a binary combination of triclosan and carbendazim to Daphnia magna

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2015.04.023openalex-snapshot

Nested interactions in the combined toxicity of uranium and cadmium to the nematode Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2015.07.012openalex-snapshot

Statistically significant deviations from additivity: What do they mean in assessing toxicity of mixtures?

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2015.07.021openalex-snapshot

Is UV radiation changing the toxicity of compounds to zebrafish embryos?

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2016.06.029openalex-snapshot

Graphene oxide alleviates the ecotoxicity of copper on the freshwater microalga Scenedesmus obliquus

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2016.11.017openalex-snapshot

Single- and mixture toxicity of three organic UV-filters, ethylhexyl methoxycinnamate, octocrylene, and avobenzone on Daphnia magna

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2017.04.020openalex-snapshot

Prediction of toxicity of zinc and nickel mixtures to Artemia sp. at various salinities: From additivity to antagonism

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2017.04.024openalex-snapshot

Effects of diuron and carbofuran and their mixtures on the microalgae Raphidocelis subcapitata

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2017.06.044openalex-snapshot

Global concentration additivity and prediction of mixture toxicities, taking nitrobenzene derivatives as an example

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2017.11.031openalex-snapshot

The ecotoxicity of binary mixtures of Imazamox and ionized ammonia on freshwater copepods: Implications for environmental risk assessment in groundwater bodies

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2018.03.003openalex-snapshot

Can chronic exposure to imidacloprid, clothianidin, and thiamethoxam mixtures exert greater than additive toxicity in Chironomus dilutus?

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2018.06.073openalex-snapshot

Effects of florfenicol and oxytetracycline on the tropical cladoceran Ceriodaphnia silvestrii: A mixture toxicity approach to predict the potential risks of antimicrobials for zooplankton

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2018.07.007openalex-snapshot

Commercial personal care product mixtures exhibit hormetic concentration-responses to Vibrio qinghaiensis sp.-Q67

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2018.12.087openalex-snapshot

Polyethylene glycol 400 significantly enhances the stimulation of 2-phenoxyethanol on Vibrio qinghaiensis sp.-Q67 bioluminescence

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