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Branched-chain amino acids in liver diseases

https://doi.org/10.21037/tgh.2018.07.06

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Serum Amino Acid Levels in Patients With Hepatocellular Carcinoma

inferredcites →https://doi.org/10.1002/14651858.cd001939openalex-snapshot

Branched-chain amino acids for hepatic encephalopathy

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Branched-chain amino acids for people with hepatic encephalopathy

inferredcites →https://doi.org/10.1002/14651858.cd001939.pub4openalex-snapshot

Branched-chain amino acids for people with hepatic encephalopathy

inferredcites →https://doi.org/10.1002/hep.23248openalex-snapshot

Branched chain amino acids enhance the maturation and function of myeloid dendritic cells ex vivo in patients with advanced cirrhosis†

inferredcites →https://doi.org/10.1002/hep.24412openalex-snapshot

Branched-chain amino acids as pharmacological nutrients in chronic liver disease

inferredcites →https://doi.org/10.1002/hep.27717openalex-snapshot

Metabolic and molecular responses to leucine‐enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

inferredcites →https://doi.org/10.1002/jcb.22688openalex-snapshot

Potential role of branched‐chain amino acids in glucose metabolism through the accelerated induction of the glucose‐sensing apparatus in the liver

inferredcites →https://doi.org/10.1002/jcb.24188openalex-snapshot

Branched‐chain amino acid deficiency stabilizes insulin‐induced vascular endothelial growth factor mRNA in hepatocellular carcinoma cells

inferredcites →https://doi.org/10.1002/jcsm.12032openalex-snapshot

Conversion of leucine to β-hydroxy-β-methylbutyrate by α-keto isocaproate dioxygenase is required for a potent stimulation of protein synthesis in L6 rat myotubes

inferredcites →https://doi.org/10.1002/mnfr.201300538openalex-snapshot

Pharmaceutical and nutraceutical approaches for preventing liver carcinogenesis: Chemoprevention of hepatocellular carcinoma using acyclic retinoid and branched‐chain amino acids

inferredcites →https://doi.org/10.1002/mnfr.201400918openalex-snapshot

Branched‐chain amino acids modulate the expression of hepatic fatty acid metabolism‐related genes in female broiler chickens

inferredcites →https://doi.org/10.1006/bbrc.1995.2391openalex-snapshot

Changes in the Ratio of Branched-Chain to Aromatic Amino Acids Affect the Secretion of Albumin in Cultured Rat Hepatocytes

inferredcites →https://doi.org/10.1007/bf02624599openalex-snapshot

Influence of branched-chain amino acid composition of culture media on the synthesis of plasma proteins by serum-free cultured rat hepatocytes

inferredcites →https://doi.org/10.1007/s00535-009-0031-0openalex-snapshot

Branched-chain amino acids suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats

inferredcites →https://doi.org/10.1007/s00535-017-1370-xopenalex-snapshot

Supplementation with branched-chain amino acids ameliorates hypoalbuminemia, prevents sarcopenia, and reduces fat accumulation in the skeletal muscles of patients with liver cirrhosis

inferredcites →https://doi.org/10.1007/s005350200082openalex-snapshot

Severe catabolic state after prolonged fasting in cirrhotic patients: effect of oral branched-chain amino-acid-enriched nutrient mixture

inferredcites →https://doi.org/10.1007/s00595-012-0288-4openalex-snapshot

Oral supplementation of branched-chain amino acids reduces early recurrence after hepatic resection in patients with hepatocellular carcinoma: a prospective study

inferredcites →https://doi.org/10.1007/s00726-011-1123-8openalex-snapshot

Isoleucine or valine deprivation stimulates fat loss via increasing energy expenditure and regulating lipid metabolism in WAT

inferredcites →https://doi.org/10.1007/s00726-017-2399-0openalex-snapshot

l-Arginine promotes protein synthesis and cell growth in brown adipocyte precursor cells via the mTOR signal pathway

inferredcites →https://doi.org/10.1007/s11011-008-9123-4openalex-snapshot

Metabolic fate of isoleucine in a rat model of hepatic encephalopathy and in cultured neural cells exposed to ammonia

inferredcites →https://doi.org/10.1007/s11011-012-9372-0openalex-snapshot

Lactulose, rifaximin or branched chain amino acids for hepatic encephalopathy: what is the evidence?

inferredcites →https://doi.org/10.1016/j.bbrc.2003.07.017openalex-snapshot

Significance of branched chain amino acids as possible stimulators of hepatocyte growth factor

inferredcites →https://doi.org/10.1016/j.bbrc.2003.11.023openalex-snapshot

Pharmacological activities of branched-chain amino acids: specificity of tissue and signal transduction

inferredcites →https://doi.org/10.1016/j.bbrc.2003.11.039openalex-snapshot

Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes

inferredcites →https://doi.org/10.1016/j.bbrc.2016.09.162openalex-snapshot

BCKA down-regulates mTORC2-Akt signal and enhances apoptosis susceptibility in cardiomyocytes

inferredcites →https://doi.org/10.1016/j.cgh.2011.08.028openalex-snapshot

Muscle Wasting Is Associated With Mortality in Patients With Cirrhosis

inferredcites →https://doi.org/10.1016/j.cld.2011.12.009openalex-snapshot

Malnutrition in Cirrhosis: Contribution and Consequences of Sarcopenia on Metabolic and Clinical Responses

inferredcites →https://doi.org/10.1016/j.clnu.2006.01.018openalex-snapshot

ESPEN Guidelines on Enteral Nutrition: Liver disease

inferredcites →https://doi.org/10.1016/j.clnu.2017.09.024openalex-snapshot

Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism

inferredcites →https://doi.org/10.1016/j.cmet.2007.08.003openalex-snapshot

Disruption of BCATm in Mice Leads to Increased Energy Expenditure Associated with the Activation of a Futile Protein Turnover Cycle

inferredcites →https://doi.org/10.1016/j.dld.2018.02.010openalex-snapshot

Hepatocellular carcinoma risk assessment by the measurement of liver stiffness variations in HCV cirrhotics treated with direct acting antivirals

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2017.01.009openalex-snapshot

High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation

inferredcites →https://doi.org/10.1016/j.hepres.2004.08.009openalex-snapshot

Effect of oral supplementation with branched-chain amino acid granules in the early stage of cirrhosis

inferredcites →https://doi.org/10.1016/j.hepres.2004.08.012openalex-snapshot

Nocturnal energy and BCAA supplementation in patients with liver cirrhosis

inferredcites →https://doi.org/10.1016/j.hepres.2004.10.010openalex-snapshot

Late evening snack and the change of blood glucose level in patients with liver cirrhosis

inferredcites →https://doi.org/10.1016/j.hepres.2004.11.009openalex-snapshot

The effect of a late evening snack in patients with liver cirrhosis

inferredcites →https://doi.org/10.1016/j.hepres.2005.01.009openalex-snapshot

Clinical comparison of branched-chain amino acid (-Leucine, -Isoleucine, -Valine) granules and oral nutrition for hepatic insufficiency in patients with decompensated liver cirrhosis (LIV–EN study)

inferredcites →https://doi.org/10.1016/j.jhep.2017.08.030openalex-snapshot

HCV eradication induced by direct-acting antiviral agents reduces the risk of hepatocellular carcinoma

inferredcites →https://doi.org/10.1016/j.jnutbio.2007.05.011openalex-snapshot

Localization of polypyrimidine-tract-binding protein is involved in the regulation of albumin synthesis by branched-chain amino acids in HepG2 cells

inferredcites →https://doi.org/10.1016/j.metabol.2012.03.011openalex-snapshot

Beneficial effect of branched-chain amino acid supplementation on glycemic control in chronic hepatitis C patients with insulin resistance: Implications for type 2 diabetes

inferredcites →https://doi.org/10.1016/j.nut.2004.07.017openalex-snapshot

Usefulness of granular BCAA after hepatectomy for liver cancer complicated with liver cirrhosis

inferredcites →https://doi.org/10.1016/j.nut.2006.10.008openalex-snapshot

BCAA-enriched snack improves nutritional state of cirrhosis

inferredcites →https://doi.org/10.1016/j.nut.2014.07.005openalex-snapshot

Sarcopenia impairs prognosis of patients with liver cirrhosis

inferredcites →https://doi.org/10.1016/j.nutres.2012.06.007openalex-snapshot

Supplementation with branched-chain amino acids attenuates hepatic apoptosis in rats with chronic liver disease

inferredcites →https://doi.org/10.1016/j.phrs.2017.12.018openalex-snapshot

Krüppel-like factor 15: Regulator of BCAA metabolism and circadian protein rhythmicity

inferredcites →https://doi.org/10.1016/s0006-291x(02)02717-1openalex-snapshot

Leucine promotes glucose uptake in skeletal muscles of rats

inferredcites →https://doi.org/10.1016/s0006-291x(03)00295-xopenalex-snapshot

Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system

inferredcites →https://doi.org/10.1016/s0016-5085(03)00323-8openalex-snapshot

Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial

inferredcites →https://doi.org/10.1016/s0950-351x(96)80771-3openalex-snapshot

Protein metabolism and liver disease

inferredcites →https://doi.org/10.1016/s1386-6346(02)00267-xopenalex-snapshot

Effect of oral supplementation with branched-chain amino acid granules on serum albumin level in the early stage of cirrhosis: a randomized pilot trial

inferredcites →https://doi.org/10.1016/s1542-3565(05)00017-0openalex-snapshot

Effects of Oral Branched-Chain Amino Acid Granules on Event-Free Survival in Patients With Liver Cirrhosis

inferredcites →https://doi.org/10.1016/s1665-2681(19)31735-1openalex-snapshot

Insulin resistance, hepatic steatosis and hepatitis C: A complex relationship with relevant clinical implications

inferredcites →https://doi.org/10.1038/ajg.2011.9openalex-snapshot

Effects of Branched-Chain Amino Acids Supplementation in Patients With Cirrhosis and a Previous Episode of Hepatic Encephalopathy: A Randomized Study

inferredcites →https://doi.org/10.1038/nm.4057openalex-snapshot

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance

inferredcites →https://doi.org/10.1038/nrendo.2014.171openalex-snapshot

Branched-chain amino acids in metabolic signalling and insulin resistance

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PROSPECTIVE RANDOMIZED CONTROL STUDY ON THE EFFECT OF BRANCHED‐CHAIN AMINO ACIDS IN PATIENTS WITH LIVER RESECTION FOR HEPATOCELLULAR CARCINOMA

inferredcites →https://doi.org/10.1046/j.1440-1746.2000.02220.xopenalex-snapshot

Effect of branched‐chain amino acids on the composition and cytolytic activity of liver‐associated lymphocytes in rats

inferredcites →https://doi.org/10.1053/j.gastro.2011.03.051openalex-snapshot

Malnutrition Impairs Interferon Signaling Through mTOR and FoxO Pathways in Patients With Chronic Hepatitis C

inferredcites →https://doi.org/10.1056/nejm199406233302501openalex-snapshot

Exercise Training and Nutritional Supplementation for Physical Frailty in Very Elderly People

inferredcites →https://doi.org/10.1074/jbc.m603536200openalex-snapshot

The Mammalian Target of Rapamycin (mTOR) Pathway Regulates Mitochondrial Oxygen Consumption and Oxidative Capacity

inferredcites →https://doi.org/10.1080/00365529850171521openalex-snapshot

Effects of Branched-Chain-Enriched Amino Acid Solution on Insulin and Glucagon Secretion and Blood Glucose Level in Liver Cirrhosis

inferredcites →https://doi.org/10.1080/01635581.2013.780628openalex-snapshot

Pre-, Peri-, and Postoperative Oral Administration of Branched-Chain Amino Acids for Primary Liver Cancer Patients for Hepatic Resection: A Systematic Review

inferredcites →https://doi.org/10.1093/ajcn/78.2.250openalex-snapshot

Essential amino acids are primarily responsible for the amino acid stimulation of muscle protein anabolism in healthy elderly adults

inferredcites →https://doi.org/10.1093/ajcn/83.2.500sopenalex-snapshot

New functions for amino acids: effects on gene transcription and translation

inferredcites →https://doi.org/10.1093/jn/130.10.2413openalex-snapshot

Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway

inferredcites →https://doi.org/10.1093/jn/130.11.2630openalex-snapshot

Stimulation of In Vitro Rat Muscle Protein Synthesis by Leucine Decreases with Age

inferredcites →https://doi.org/10.1093/jn/131.4.1171openalex-snapshot

Oral Administration of Leucine Stimulates Ribosomal Protein mRNA Translation but Not Global Rates of Protein Synthesis in the Liver of Rats

inferredcites →https://doi.org/10.1093/jn/136.1.277sopenalex-snapshot

Amino Acids and Muscle Loss with Aging

inferredcites →https://doi.org/10.1096/fj.03-1409fjeopenalex-snapshot

Amino acids and leucine allow insulin activation of the PKB/mTOR pathway in normal adipocytes treated with wortmannin and in adipocytes from db/db mice

inferredcites →https://doi.org/10.1097/00000658-198403000-00007openalex-snapshot

Branched Chain Metabolic Support

inferredcites →https://doi.org/10.1097/00004836-198410000-00012openalex-snapshot

Significance of Serum Aminograms in Diagnosis and Prognosis of Liver Diseases

inferredcites →https://doi.org/10.1097/mcg.0b013e31826be9adopenalex-snapshot

The Effect of Long-term Supplementation With Branched-chain Amino Acid Granules in Patients With Hepatitis C Virus-related Hepatocellular Carcinoma After Radiofrequency Thermal Ablation

inferredcites →https://doi.org/10.1097/mco.0b013e3283413726openalex-snapshot

Branched-chain amino acids in liver disease: new aspects of long known phenomena

inferredcites →https://doi.org/10.1097/meg.0000000000000986openalex-snapshot

Efficacy of branched-chain amino acid supplementation and walking exercise for preventing sarcopenia in patients with liver cirrhosis

inferredcites →https://doi.org/10.1111/hepr.12640openalex-snapshot

Impact of branched‐chain amino acid supplementation on survival in patients with advanced hepatocellular carcinoma treated with sorafenib: A multicenter retrospective cohort study

inferredcites →https://doi.org/10.1111/j.1349-7006.2009.01402.xopenalex-snapshot

Dietary supplementation with branched‐chain amino acids suppresses diethylnitrosamine‐induced liver tumorigenesis in obese and diabetic C57BL/KsJ‐db/db mice

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Modulation of human lymphocyte proliferation by amino acids

inferredcites →https://doi.org/10.1111/j.1440-1746.2010.06306.xopenalex-snapshot

Effects of branched‐chain amino acid‐enriched nutrient for patients with hepatocellular carcinoma following radiofrequency ablation: A one‐year prospective trial

inferredcites →https://doi.org/10.1111/j.1478-3231.2007.01559.xopenalex-snapshot

Branched‐chain amino acids improve insulin resistance in patients with hepatitis C virus‐related liver disease: report of two cases

inferredcites →https://doi.org/10.1111/j.1872-034x.2007.00166.xopenalex-snapshot

Restoration of innate host defense responses by oral supplementation of branched‐chain amino acids in decompensated cirrhotic patients

inferredcites →https://doi.org/10.1111/j.1872-034x.2007.00268.xopenalex-snapshot

Measurement of serum branched‐chain amino acids to tyrosine ratio level is useful in a prediction of a change of serum albumin level in chronic liver disease

inferredcites →https://doi.org/10.1111/j.1872-034x.2008.00391.xopenalex-snapshot

Effects of a late evening snack combined with α‐glucosidase inhibitor on liver cirrhosis

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Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis B virus infection for the fiscal year 2008 in Japan

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Guidelines for the treatment of chronic hepatitis and cirrhosis due to hepatitis C virus infection for the fiscal year 2008 in Japan

inferredcites →https://doi.org/10.1111/j.1872-034x.2010.00701.xopenalex-snapshot

Effect of an oral branched chain amino acid‐enriched snack in cirrhotic patients with sleep disturbance

inferredcites →https://doi.org/10.1111/j.1872-034x.2011.00795.xopenalex-snapshot

Effects of late evening snack including branched‐chain amino acid on the function of hepatic parenchymal cells in patients with liver cirrhosis

inferredcites →https://doi.org/10.1152/ajpendo.00520.2015openalex-snapshot

Enteral β-hydroxy-β-methylbutyrate supplementation increases protein synthesis in skeletal muscle of neonatal pigs

inferredcites →https://doi.org/10.1152/ajpendo.1993.264.5.e693openalex-snapshot

Myofibrillar protein synthesis in young and old men

inferredcites →https://doi.org/10.1152/ajpendo.2000.278.4.e620openalex-snapshot

Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78–84 and 23–32 yr olds

inferredcites →https://doi.org/10.1159/000327571openalex-snapshot

Oral Branched-Chain Amino Acid Granules Reduce the Incidence of Hepatocellular Carcinoma and Improve Event-Free Survival in Patients with Liver Cirrhosis

inferredcites →https://doi.org/10.1159/000343094openalex-snapshot

Valine, a Branched-Chain Amino Acid, Reduced HCV Viral Load and Led to Eradication of HCV by Interferon Therapy in a Decompensated Cirrhotic Patient

inferredcites →https://doi.org/10.1159/000343857openalex-snapshot

Quantitative Levels of Hepatitis B Virus DNA and Surface Antigen and the Risk of Hepatocellular Carcinoma in Patients with Hepatitis B Receiving Long-Term Nucleos(t)ide Analogue Therapy

inferredcites →https://doi.org/10.1172/jci108375openalex-snapshot

Effect of protein ingestion on splanchnic and leg metabolism in normal man and in patients with diabetes mellitus.

inferredcites →https://doi.org/10.1177/0148607183007006521openalex-snapshot

Does Modified Amino Acid Total Parenteral Nutrition Alter Immune‐Response in High Level Surgical Stress

inferredcites →https://doi.org/10.1186/2049-3002-2-6openalex-snapshot

Leucine supplementation differentially enhances pancreatic cancer growth in lean and overweight mice

inferredcites →https://doi.org/10.1207/s15327914nc391_17openalex-snapshot

Effect of the Molar Ratio of Branched-Chain to Aromatic Amino Acids on Growth and Albumin mRNA Expression of Human Liver Cancer Cell Lines in a Serum-Free Medium

inferredcites →https://doi.org/10.1245/s10434-016-5348-3openalex-snapshot

A Randomized Clinical Trial of Preoperative Administration of Branched-Chain Amino Acids to Prevent Postoperative Ascites in Patients with Liver Resection for Hepatocellular Carcinoma

inferredcites →https://doi.org/10.1248/bpb.31.469openalex-snapshot

Acute and Chronic Treatment of L-Isoleucine Ameliorates Glucose Metabolism in Glucose-Intolerant and Diabetic Mice

inferredcites →https://doi.org/10.1371/journal.pone.0082346openalex-snapshot

Branched Chain Amino Acid Suppresses Hepatocellular Cancer Stem Cells through the Activation of Mammalian Target of Rapamycin

inferredcites →https://doi.org/10.14814/phy2.13444openalex-snapshot

Effect of light-load resistance exercise on postprandial amino acid transporter expression in elderly men

inferredcites →https://doi.org/10.1507/endocrj.k10e-221openalex-snapshot

The effects of branched-chain amino acid granules on the accumulation of tissue triglycerides and uncoupling proteins in diet-induced obese mice

inferredcites →https://doi.org/10.18632/oncotarget.18447openalex-snapshot

Evaluation of the branched-chain amino acid-to-tyrosine ratio prior to treatment as a prognostic predictor in patients with liver cirrhosis

inferredcites →https://doi.org/10.18632/oncotarget.22205openalex-snapshot

Alteration of muscle fiber characteristics and the AMPK-SIRT1-PGC-1α axis in skeletal muscle of growing pigs fed low-protein diets with varying branched-chain amino acid ratios

inferredcites →https://doi.org/10.2169/internalmedicine.37.429openalex-snapshot

Preferential Use of Branched-Chain Amino Acids as an Energy Substrate in Patients with Liver Cirrhosis.

inferredcites →https://doi.org/10.2169/internalmedicine.51.7578openalex-snapshot

Long-term Branched-chain Amino Acid Supplementation Improves Glucose Tolerance in Patients with Nonalcoholic Steatohepatitis-related Cirrhosis

inferredcites →https://doi.org/10.2174/092986709789909620openalex-snapshot

Branched-Chain Amino Acids and Pigment Epithelium-Derived Factor: Novel Therapeutic Agents for Hepatitis C Virus-Associated Insulin Resistance

inferredcites →https://doi.org/10.2337/db07-0123openalex-snapshot

Increasing Dietary Leucine Intake Reduces Diet-Induced Obesity and Improves Glucose and Cholesterol Metabolism in Mice via Multimechanisms

inferredcites →https://doi.org/10.3177/jnsv.57.114openalex-snapshot

Effects of Branched-Chain Amino Acid Supplementation on Plasma Concentrations of Free Amino Acids, Insulin, and Energy Substrates in Young Men

inferredcites →https://doi.org/10.3389/fimmu.2018.00005openalex-snapshot

Nutrients Mediate Intestinal Bacteria–Mucosal Immune Crosstalk

inferredcites →https://doi.org/10.3390/ijms19040954openalex-snapshot

Branched Chain Amino Acids: Beyond Nutrition Metabolism

inferredcites →https://doi.org/10.3748/wjg.v18.i12.1379openalex-snapshot

Branched-chain amino acid treatment before transcatheter arterial chemoembolization for hepatocellular carcinoma

inferredcites →https://doi.org/10.3748/wjg.v19.i43.7620openalex-snapshot

Branched-chain amino acids in liver diseases

inferredcites →https://doi.org/10.3748/wjg.v20.i23.7298openalex-snapshot

Impairment of innate immune responses in cirrhotic patients and treatment by branched-chain amino acids

inferredcites →https://doi.org/10.3892/ijmm.22.1.105openalex-snapshot

Branched-chain amino acid-enriched supplementation improves insulin resistance in patients with chronic liver disease

inferredcites →https://doi.org/10.4049/jimmunol.179.10.7137openalex-snapshot

Extracellular Branched-Chain Amino Acids, Especially Valine, Regulate Maturation and Function of Monocyte-Derived Dendritic Cells

inferredcites →https://doi.org/10.4143/crt.2011.43.1.24openalex-snapshot

Effect of Oral Supplementation with Branched-chain Amino Acid (BCAA) during Radiotherapy in Patients with Hepatocellular Carcinoma: A Double-Blind Randomized Study

inferredcites →https://doi.org/10.5754/hge10389openalex-snapshot

Effects of Branched-Chain Amino Acid Infusions on Liver Regeneration and Plasma Amino Acid Patterns in Partially Hepatectomized Rats

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Quality of life indicators in hepatic encephalopathy following supplementation with branched chain amino acids and/or synbiotics: A post‐hoc analysis

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Liver

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Effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults: a systematic review and meta-analysis

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Branched-Chain Amino Acid Supplementation and Clinical Outcomes in Liver Cirrhosis: A Propensity Score-Matched Multicenter Retrospective Cohort Study

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Branched-chain amino acids and their metabolites decrease human and rat hepatic stellate cell activation

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Shifts in gut microbiota and their metabolites induced by bariatric surgery. Impact of factors shaping gut microbiota on bariatric surgery outcomes

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Design and Numerical Analysis of a Label-free Nano Biosensor Employing a Bi₂Se₃/MoS₂ Heterostructure for Enhanced Detection of Branched-chain Amino Acids (BCAAs)

inferred← citeshttps://doi.org/10.1007/s11901-021-00563-zopenalex-snapshot

Dietary Interventions in Liver Diseases: Focus on MAFLD and Cirrhosis

inferred← citeshttps://doi.org/10.1016/b978-0-323-90113-0.00002-xopenalex-snapshot

The therapeutic role of microbial metabolites in human health and diseases

inferred← citeshttps://doi.org/10.1016/bs.pmbts.2022.07.012openalex-snapshot

Human microbiome and cardiovascular diseases

inferred← citeshttps://doi.org/10.1016/j.ab.2022.114696openalex-snapshot

Amino acids, ammonia, and hepatic encephalopathy

inferred← citeshttps://doi.org/10.1016/j.apsb.2021.03.038openalex-snapshot

Notoginsenoside Ft1 acts as a TGR5 agonist but FXR antagonist to alleviate high fat diet-induced obesity and insulin resistance in mice

inferred← citeshttps://doi.org/10.1016/j.apsb.2026.09.029openalex-snapshot

Yupingfeng powder attenuates influenza A virus induced lung injury via gut microbiota-dependent modulation of branched-chain amino acid metabolism and macrophage polarization

inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2024.119054openalex-snapshot

Liver metabolism in human MASLD: A review of recent advancements using human tissue metabolomics

inferred← citeshttps://doi.org/10.1016/j.autrev.2022.103169openalex-snapshot

Psoriasis: Interplay between dysbiosis and host immune system

inferred← citeshttps://doi.org/10.1016/j.cgh.2024.09.041openalex-snapshot

Lifestyle and Pharmacologic Approaches to Prevention of Metabolic Dysfunction-associated Steatotic Liver Disease-related Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.1016/j.clnu.2022.03.027openalex-snapshot

Efficacy of branched chain amino acids supplementation in liver cirrhosis: A systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1016/j.cnd.2019.01.003openalex-snapshot

Acides aminés à chaîne ramifiée et insulino-sensibilité : amis ou ennemis ?

inferred← citeshttps://doi.org/10.1016/j.crmicr.2025.100442openalex-snapshot

Gut microbial communities in chronic rhinosinusitis patients in response to 1,8-Cineol treatment

inferred← citeshttps://doi.org/10.1016/j.csbj.2022.10.030openalex-snapshot

Advances in multi-omics study of biomarkers of glycolipid metabolism disorder

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116230openalex-snapshot

Deciphering the impact of greenhouse pesticides on hepatic metabolism profile: Toxicity experiments on HepG2 cells using chlorpyrifos and emamectin benzoate

inferred← citeshttps://doi.org/10.1016/j.fbio.2024.103809openalex-snapshot

Hepatoprotective effects of high Fischer's ratio oligopeptides from goat whey against CCl4-Induced acute liver injury in mice

inferred← citeshttps://doi.org/10.1016/j.fbio.2025.106205openalex-snapshot

Upcycling fish byproducts for skin health: An enzymatic approach to sustainable nutricosmetics

inferred← citeshttps://doi.org/10.1016/j.isci.2023.107754openalex-snapshot

Aggravated hepatic fibrosis induced by phenylalanine and tyrosine was ameliorated by chitooligosaccharides supplementation

inferred← citeshttps://doi.org/10.1016/j.jchromb.2020.122250openalex-snapshot

An improved pseudotargeted GC–MS/MS-based metabolomics method and its application in radiation-induced hepatic injury in a rat model

inferred← citeshttps://doi.org/10.1016/j.jff.2020.104232openalex-snapshot

Supplementation of beef extract improves chemotherapy-induced fatigue and toxic effects in mice

inferred← citeshttps://doi.org/10.1016/j.jff.2025.107073openalex-snapshot

Amino acids mixture ameliorates alcohol-induced liver and behavioral impairments by modulating Nrf2 and ethanol metabolism

inferred← citeshttps://doi.org/10.1016/j.jhep.2021.12.019openalex-snapshot

Histone acetylation of bile acid transporter genes plays a critical role in cirrhosis

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2025.109839openalex-snapshot

The supply of branched-chain amino acids and branched-chain keto acids alter lipid metabolism, oxidative stress, and apoptosis in primary bovine hepatocytes

inferred← citeshttps://doi.org/10.1016/j.jpba.2024.116369openalex-snapshot

Amino acid metabolomics and machine learning-driven assessment of future liver remnant growth after hepatectomy in livers of various backgrounds

inferred← citeshttps://doi.org/10.1016/j.liver.2021.100060openalex-snapshot

Nutritional therapy to cirrhotic patients on transplantation waiting lists

inferred← citeshttps://doi.org/10.1016/j.nut.2021.111194openalex-snapshot

Branched-chain amino acids protect the liver from cirrhotic injury via suppression of activation of lipopolysaccharide-binding protein, toll-like receptor 4, and signal transducer and activator of transcription 3, as well as Enterococcus faecalis translocation

inferred← citeshttps://doi.org/10.1016/j.tice.2026.103357openalex-snapshot

Indispensable amino acids vastly protect against CCl4-mediated aggravated liver cirrhosis and immunotoxicity

inferred← citeshttps://doi.org/10.1016/j.vas.2023.100302openalex-snapshot

The histopathological changes of liver and testis of Japanese quail chicks fed different levels of dietary L-valine

inferred← citeshttps://doi.org/10.1016/j.xcrm.2024.101853openalex-snapshot

Metabolomics at the cutting edge of risk prediction of MASLD

inferred← citeshttps://doi.org/10.1016/j.yexcr.2025.114853openalex-snapshot

MicroRNA-mediated metabolic control in HCC: From molecular networks to therapy

inferred← citeshttps://doi.org/10.1021/acs.analchem.4c06133openalex-snapshot

Multiscale Synergy Networks Offer Insights into Disease and Comorbidity Mechanisms

inferred← citeshttps://doi.org/10.1021/acsnutrsci.5c00020openalex-snapshot

Millets as Functional Foods for Liver Health: Insights into the Hepatoprotective Potential of Their Biomolecules

inferred← citeshttps://doi.org/10.1038/s41392-023-01569-3openalex-snapshot

Amino acid metabolism in health and disease

inferred← citeshttps://doi.org/10.1038/s41430-025-01642-wopenalex-snapshot

Exercise and nutrition interventions for sarcopenia in cirrhosis: a systematic review and network meta-analysis of randomized controlled trials

inferred← citeshttps://doi.org/10.1038/s41522-023-00398-0openalex-snapshot

Impaired flux of bile acids from the liver to the gut reveals microbiome-immune interactions associated with liver damage

inferred← citeshttps://doi.org/10.1038/s41598-020-59996-zopenalex-snapshot

Hyperproliferation is the main driver of metabolomic changes in psoriasis lesional skin

inferred← citeshttps://doi.org/10.1038/s41598-024-67498-5openalex-snapshot

Anti-inflammatory response to 1,8-Cineol and associated microbial communities in Otitis media patients

inferred← citeshttps://doi.org/10.1038/s41598-026-46326-yopenalex-snapshot

Low Fischer’s ratio is associated with increased mortality in patients with kidney failure

inferred← citeshttps://doi.org/10.1038/s44355-024-00001-zopenalex-snapshot

Alterations of the peptidomic composition of peripheral plasma after portal hypertension correction by transjugular intrahepatic portosystemic shunt

inferred← citeshttps://doi.org/10.1053/j.jrn.2021.05.008openalex-snapshot

Effect of Branched-Chain Amino Acid Infusion on In-Hospital Mortality of Patients With Hepatic Encephalopathy and End-Stage Kidney Disease: A Retrospective Cohort Study Using a National Inpatient Database

inferred← citeshttps://doi.org/10.1080/10408363.2024.2323132openalex-snapshot

The role of bile acid metabolism in bone and muscle: from analytics to mechanisms

inferred← citeshttps://doi.org/10.1080/10837450.2022.2129687openalex-snapshot

Combating hematopoietic and hepatocellular abnormalities resulting from administration of cisplatin: role of liver targeted glycyrrhetinic acid nanoliposomes loaded with amino acids

inferred← citeshttps://doi.org/10.1093/gastro/goaa066openalex-snapshot

Metabolic alterations and vulnerabilities in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1093/infdis/jiae157openalex-snapshot

CsiR-Mediated Signal Transduction Pathway in Response to Low Iron Conditions Promotes Escherichia coli K1 Invasion and Penetration of the Blood-Brain Barrier

inferred← citeshttps://doi.org/10.1097/meg.0000000000002595openalex-snapshot

Management of minimal and overt hepatic encephalopathy with branched-chain amino acids: a review of the evidence

inferred← citeshttps://doi.org/10.1101/2025.06.11.659225openalex-snapshot

Chenodeoxycholic Acid Modulation via Bacteroides intestinalis AM1 underscores a Novel Approach in Acute Liver Failure

inferred← citeshttps://doi.org/10.1101/2025.10.30.685560openalex-snapshot

Effect of Age and Sex on BCAA Metabolism in Mice

inferred← citeshttps://doi.org/10.1111/eci.13909openalex-snapshot

Systematic review with meta‐analysis: Branched‐chain amino acid supplementation in liver disease

inferred← citeshttps://doi.org/10.1111/eci.70096openalex-snapshot

Branched‐chain amino acids and all‐cause mortality in patients with liver cirrhosis, and the onset of diabetes in liver transplant recipients

inferred← citeshttps://doi.org/10.1111/obr.13341openalex-snapshot

The gut microbiota and its products: Establishing causal relationships with obesity related outcomes

inferred← citeshttps://doi.org/10.1124/dmd.121.000477openalex-snapshot

Perfluorinated Carboxylic Acids with Increasing Carbon Chain Lengths Upregulate Amino Acid Transporters and Modulate Compensatory Response of Xenobiotic Transporters in HepaRG Cells

inferred← citeshttps://doi.org/10.1128/msystems.00023-24openalex-snapshot

Alterations in the gut microbiota and its metabolites contribute to metabolic maladaptation in dairy cows during the development of hyperketonemia

inferred← citeshttps://doi.org/10.1136/gutjnl-2020-323071openalex-snapshot

Gut microbiota-derived metabolites as central regulators in metabolic disorders

inferred← citeshttps://doi.org/10.1145/3386052.3386077openalex-snapshot

Identification of the Association between Hepatitis B Virus and Liver Cancer using Machine Learning Approaches based on Amino Acid

inferred← citeshttps://doi.org/10.1155/2021/3259238openalex-snapshot

Oridonin Alters Hepatic Urea Cycle via Gut Microbiota and Protects against Acetaminophen‐Induced Liver Injury

inferred← citeshttps://doi.org/10.1186/s12876-025-03696-3openalex-snapshot

Prospective randomized, placebo-controlled study: role of branched-chain amino acids infusion as adjunct therapy post-liver surgery for patients in the intensive care unit

inferred← citeshttps://doi.org/10.1186/s12877-024-05445-9openalex-snapshot

Relationship between macronutrients and energy intake and liver serum transaminase levels in elderly athletes and non-athletes: findings from the Neyshabur longitudinal study on aging

inferred← citeshttps://doi.org/10.1186/s12920-025-02232-2openalex-snapshot

Assessment of genetic and metabolite associations of branched chain amino acids with metabolic disease in the UK Biobank using Mendelian randomization

inferred← citeshttps://doi.org/10.1186/s12970-020-00355-8openalex-snapshot

The addition of an amylopectin/chromium complex to branched-chain amino acids enhances muscle protein synthesis in rat skeletal muscle

inferred← citeshttps://doi.org/10.12659/aot.919502openalex-snapshot

Clinical Outcome of Residual Liver Volume and Hepatic Steatosis After Right-Lobe Living-Donor Hepatectomy

inferred← citeshttps://doi.org/10.12677/hjbm.2024.141009openalex-snapshot

Research Progress in the Treatment of Diabetic Nephropathy Based on Intestinal Microecology

inferred← citeshttps://doi.org/10.14302/issn.2372-6601.jhor-19-3095openalex-snapshot

Amino Acids and their Derivatives in Pathogenesis and Treatment of Liver Diseases

inferred← citeshttps://doi.org/10.14309/ctg.0000000000000222openalex-snapshot

Safety, Tolerability, and Physiological Effects of AXA1665, a Novel Composition of Amino Acids, in Subjects With Child–Pugh A and B Cirrhosis

inferred← citeshttps://doi.org/10.14336/ad.2022.0104openalex-snapshot

Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives

inferred← citeshttps://doi.org/10.14710/jbtr.v8i3.15078openalex-snapshot

Hepatogomax Improves Serum Albumin and Transaminase Enzyme Activity Levels in Sprague Dawley Rats Liver Cirrhosis

inferred← citeshttps://doi.org/10.15586/jrenhep.2019.56openalex-snapshot

Wasting Away with Cirrhosis: A Review of Hepatic Sarcopenia

inferred← citeshttps://doi.org/10.21037/tgh-24-14openalex-snapshot

Systematic metabolic profiling of mice with caerulein-induced acute pancreatitis

inferred← citeshttps://doi.org/10.21111/dnj.v3i1.3029openalex-snapshot

PENGARUH PEMBERIAN AMINOFUSIN HEPAR TERHADAP KADAR ALBUMIN DAN STATUS GIZI PASIEN SIROSIS DI RSUD CENGKARENG

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2475645/v1openalex-snapshot

Identification and validation of prognostic features of amino acid metabolism-related lncRNAs in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2475645/v2openalex-snapshot

Identification and validation of prognostic features of amino acid metabolism-related lncRNAs in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2524694/v1openalex-snapshot

The histological and pathological changes of liver and testis of Japanese quails fed different levels of dietary L-valine

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2769956/v1openalex-snapshot

Plasma meta-proteome and metabolome identify novel bacterial peptides and metabolites predictive of poor outcomes in Acute Liver Failure

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3898120/v1openalex-snapshot

Metabolomics-based Investigation of Primary Biliary Cholangitis: A Cholestatic Liver Disease

inferred← citeshttps://doi.org/10.21203/rs.3.rs-90745/v1openalex-snapshot

1H-NMR Metabolomics Analysis of The Intervention Effects of Ruangan Xiaoji Decoction on CCl4 Induced Liver Fibrosis in Rats

inferred← citeshttps://doi.org/10.2147/dmso.s221642openalex-snapshot

Branched Chain Amino Acids Protects Rat Mesangial Cells from High Glucose by Modulating TGF-β1 and BMP-7

inferred← citeshttps://doi.org/10.21608/bfsa.2023.327720openalex-snapshot

DISTURBANCES IN PLASMA ALIPHATIC AND AROMATIC AMINO ACIDS METABOLOMIC PROFILES IN EGYPTIAN OBESE WOMEN

inferred← citeshttps://doi.org/10.2174/0115680096274860231111210214openalex-snapshot

Investigating the Influence of Gut Microbiota-related Metabolites in Gastrointestinal Cancer

inferred← citeshttps://doi.org/10.22259/2639-3581.0202005openalex-snapshot

Amino Acids in the Diagnosis and Treatment of Liver Damage (Review)

inferred← citeshttps://doi.org/10.26717/bjstr.2019.23.003904openalex-snapshot

Amino Acids and Their Derivatives in Pathogenesis and Treatment of Liver Diseases (Mini-Review)

inferred← citeshttps://doi.org/10.30867/action.v8i2.969openalex-snapshot

Effect of hepatogomax on serum alkaline phosphatase, bilirubin, gamma-glutamyl transferase levels in Sprague Dawley rats cirrhosis

inferred← citeshttps://doi.org/10.31146/1682-8658-ecg-229-9-110-118openalex-snapshot

Sarcopenia and non-alcoholic fatty liver disease - complex pathogenetic relationships

inferred← citeshttps://doi.org/10.31146/1682-8658-ecg-236-4-3-36openalex-snapshot

Sarcopenia in patients with non-alcoholic fatty liver disease: pathogenesis, diagnosis and treatment (expert opinion)

inferred← citeshttps://doi.org/10.33140/mcr.05.01.06openalex-snapshot

Free Amino Acids in the Diagnosis and Treatment of Pathology the Hepatobiliary System (Review)

inferred← citeshttps://doi.org/10.3389/fimmu.2023.1124704openalex-snapshot

Gut microbiota and its metabolites – molecular mechanisms and management strategies in diabetic kidney disease

inferred← citeshttps://doi.org/10.3389/fimmu.2026.1734093openalex-snapshot

Particularly strong immune response to influenza vaccination in patients with decompensated liver cirrhosis linked to systemic inflammation

inferred← citeshttps://doi.org/10.3389/fmed.2024.1334865openalex-snapshot

Distinct metabolomic and lipidomic profiles in serum samples of patients with primary sclerosing cholangitis

inferred← citeshttps://doi.org/10.3389/fmicb.2025.1547348openalex-snapshot

Comparative analysis of the fecal microbiota in Père David's deer and five other captive deer species

inferred← citeshttps://doi.org/10.3389/fneur.2022.744945openalex-snapshot

The Effect of Branched Chain Amino Acid Supplementation on Stroke-Related Sarcopenia

inferred← citeshttps://doi.org/10.3389/fnut.2021.716613openalex-snapshot

Secondary Malnutrition and Nutritional Intervention in Cholestatic Liver Diseases in Infants

inferred← citeshttps://doi.org/10.3389/fnut.2022.1019430openalex-snapshot

Gut microbial response to host metabolic phenotypes

inferred← citeshttps://doi.org/10.3389/fphar.2021.723798openalex-snapshot

Glucose and Amino Acid Metabolic Dependencies Linked to Stemness and Metastasis in Different Aggressive Cancer Types

inferred← citeshttps://doi.org/10.3390/biom13050824openalex-snapshot

Branched Chain Amino Acids Are Associated with Physical Performance in Patients with End-Stage Liver Disease

inferred← citeshttps://doi.org/10.3390/biomedicines10061444openalex-snapshot

The Emerging Role of Branched-Chain Amino Acids in Liver Diseases

inferred← citeshttps://doi.org/10.3390/biomedicines14092082openalex-snapshot

Sarcopenia and Skeletal Muscle Dysfunction in Liver Cirrhosis: Clinical Perspectives of Myostatin Inhibition

inferred← citeshttps://doi.org/10.3390/cancers11101497openalex-snapshot

Comprehensive Metabolomic Search for Biomarkers to Differentiate Early Stage Hepatocellular Carcinoma from Cirrhosis

inferred← citeshttps://doi.org/10.3390/cells11030338openalex-snapshot

Sarcopenia Is a Cause and Consequence of Metabolic Dysregulation in Aging Humans: Effects of Gut Dysbiosis, Glucose Dysregulation, Diet and Lifestyle

inferred← citeshttps://doi.org/10.3390/healthcare13233029openalex-snapshot

The Role of the Gut Microbiome Dysbiosis in Metabolic Dysfunction: A Mini Review

inferred← citeshttps://doi.org/10.3390/ijms23074022openalex-snapshot

The Critical Role of the Branched Chain Amino Acids (BCAAs) Catabolism-Regulating Enzymes, Branched-Chain Aminotransferase (BCAT) and Branched-Chain α-Keto Acid Dehydrogenase (BCKD), in Human Pathophysiology

inferred← citeshttps://doi.org/10.3390/ijms23168999openalex-snapshot

The Link between Gut Microbiota and Hepatic Encephalopathy

inferred← citeshttps://doi.org/10.3390/ijms24087463openalex-snapshot

Metabolic Reprogramming of HCC: A New Microenvironment for Immune Responses

inferred← citeshttps://doi.org/10.3390/ijms26031372openalex-snapshot

Correlations Between Gut Microbiota Composition, Medical Nutrition Therapy, and Insulin Resistance in Pregnancy—A Narrative Review

inferred← citeshttps://doi.org/10.3390/jcm11247337openalex-snapshot

Role of Branched-Chain Amino Acids and Their Derivative β-Hydroxy-β-Methylbutyrate in Liver Cirrhosis

inferred← citeshttps://doi.org/10.3390/jcm9082381openalex-snapshot

Relationship between Osteosarcopenia and Frailty in Patients with Chronic Liver Disease

inferred← citeshttps://doi.org/10.3390/jcm9103239openalex-snapshot

Low Serum Branched-chain Amino Acid and Insulin-Like Growth Factor-1 Levels Are Associated with Sarcopenia and Slow Gait Speed in Patients with Liver Cirrhosis

inferred← citeshttps://doi.org/10.3390/life11030250openalex-snapshot

Emerging Treatment Options for Sarcopenia in Chronic Liver Disease

inferred← citeshttps://doi.org/10.3390/muscles3010008openalex-snapshot

Clinical and Therapeutic Implications of BCAAs Metabolism during Chronic Liver Disease in Humans: Crosstalk between Skeletal Muscle and Liver

inferred← citeshttps://doi.org/10.3390/nu12051429openalex-snapshot

Effects of Branched-Chain Amino Acid (BCAA) Supplementation on the Progression of Advanced Liver Disease: A Korean Nationwide, Multicenter, Prospective, Observational, Cohort Study

inferred← citeshttps://doi.org/10.3390/nu15194190openalex-snapshot

Use of Branched-Chain Amino Acids as a Potential Treatment for Improving Nutrition-Related Outcomes in Advanced Chronic Liver Disease

inferred← citeshttps://doi.org/10.3390/nu16172838openalex-snapshot

Interactions between Gut Microbiota and Natural Bioactive Polysaccharides in Metabolic Diseases: Review

inferred← citeshttps://doi.org/10.3390/nu16203538openalex-snapshot

Sportomics Analyses of the Exercise-Induced Impact on Amino Acid Metabolism and Acute-Phase Protein Kinetics in Female Olympic Athletes

inferred← citeshttps://doi.org/10.3390/nu17213346openalex-snapshot

Protein and Macronutrient Metabolism in Liver Cirrhosis: About Sarcopenia

inferred← citeshttps://doi.org/10.3390/ruminants5040051openalex-snapshot

The Basics of Clinical Nutrition for Compromised Ruminants—A Narrative Review

inferred← citeshttps://doi.org/10.3390/tropicalmed7120437openalex-snapshot

Evaluation of Amino Acids Profile as Non-Invasive Biomarkers of Hepatocellular Carcinoma in Egyptians

inferred← citeshttps://doi.org/10.34175/jno201902004openalex-snapshot

Protein Supplementation for the Prevention and Management of Sarcopenia in the Elderly

inferred← citeshttps://doi.org/10.4240/wjgs.v15.i11.2596openalex-snapshot

Effect of perioperative branched chain amino acids supplementation in liver cancer patients undergoing surgical intervention: A systematic review

inferred← citeshttps://doi.org/10.4251/wjgo.v13.i10.1440openalex-snapshot

Nutritional therapy for hepatocellular carcinoma

inferred← citeshttps://doi.org/10.4291/wjgp.v16.i4.109860openalex-snapshot

Metabolic changes after hepatectomy: Implications for perioperative management and long-term outcomes

inferred← citeshttps://doi.org/10.5009/gnl250187openalex-snapshot

Precision Strategy for Hepatocellular Carcinoma Surveillance after Hepatitis C Cure: Debates across Guidelines

inferred← citeshttps://doi.org/10.53350/pjmhs20221612527openalex-snapshot

A Study on the Role of Lactulose on Hepatic Encephalopathy Among Cirrhotic Patients with Acute Upper Gastrointestinal Bleeding

inferred← citeshttps://doi.org/10.7554/elife.80638openalex-snapshot

Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats and humans

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