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METTL14 Regulates Autophagy and Osteogenic Differentiation of BMSCs Targeting Beclin-1 via an M 6 A-IGF2BPs-Dependent Mechanism

https://doi.org/10.2139/ssrn.3940258
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jbmr.3756openalex-extracted
Beclin1 Modulates Bone Homeostasis by Regulating Osteoclast and Chondrocyte Differentiation
inferredcites →https://doi.org/10.1007/s00198-018-4573-yopenalex-extracted
Genome-wide identification of m6A-associated SNPs as potential functional variants for bone mineral density
inferredcites →https://doi.org/10.1016/j.bbadis.2018.09.015openalex-extracted
The GDF11-FTO-PPARγ axis controls the shift of osteoporotic MSC fate to adipocyte and inhibits bone formation during osteoporosis
inferredcites →https://doi.org/10.1016/j.cell.2007.12.018openalex-extracted
Autophagy in the Pathogenesis of Disease
inferredcites →https://doi.org/10.1016/j.cell.2015.05.014openalex-extracted
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
inferredcites →https://doi.org/10.1016/j.molcel.2010.09.023openalex-extracted
Autophagy and the Integrated Stress Response
inferredcites →https://doi.org/10.1016/j.molcel.2012.10.015openalex-extracted
ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility
inferredcites →https://doi.org/10.1016/j.molcel.2016.05.041openalex-extracted
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
inferredcites →https://doi.org/10.1016/j.omtn.2019.12.001openalex-extracted
m6A Methylation of Precursor-miR-320/RUNX2 Controls Osteogenic Potential of Bone Marrow-Derived Mesenchymal Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2017.11.016openalex-extracted
METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification
inferredcites →https://doi.org/10.1016/j.tibs.2021.01.006openalex-extracted
Regulation of Autophagy Enzymes by Nutrient Signaling
inferredcites →https://doi.org/10.1016/s0140-6736(18)32112-3openalex-extracted
Osteoporosis
inferredcites →https://doi.org/10.1038/cr.2014.3openalex-extracted
Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
inferredcites →https://doi.org/10.1038/cr.2017.117openalex-extracted
Mettl3-/Mettl14-mediated mRNA N6-methyladenosine modulates murine spermatogenesis
inferredcites →https://doi.org/10.1038/mt.2015.152openalex-extracted
Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis
inferredcites →https://doi.org/10.1038/ncb2902openalex-extracted
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells
inferredcites →https://doi.org/10.1038/nchembio.687openalex-extracted
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
inferredcites →https://doi.org/10.1038/s41418-018-0254-9openalex-extracted
Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulation
inferredcites →https://doi.org/10.1038/s41419-020-03315-xopenalex-extracted
ALKBH5 suppresses tumor progression via an m6A-dependent epigenetic silencing of pre-miR-181b-1/YAP signaling axis in osteosarcoma
inferredcites →https://doi.org/10.1038/s41422-018-0034-6openalex-extracted
RNA N6-methyladenosine modification in cancers: current status and perspectives
inferredcites →https://doi.org/10.1038/s41556-018-0045-zopenalex-extracted
Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation
inferredcites →https://doi.org/10.1038/s41556-021-00669-yopenalex-extracted
Autophagosome biogenesis comes out of the black box
inferredcites →https://doi.org/10.1038/s41593-017-0057-1openalex-extracted
N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications
inferredcites →https://doi.org/10.1074/jbc.m112.444190openalex-extracted
Suppression of Autophagy in Osteocytes Mimics Skeletal Aging
inferredcites →https://doi.org/10.1080/15548627.2018.1483807openalex-extracted
Defective autophagy in osteoblasts induces endoplasmic reticulum stress and causes remarkable bone loss
inferredcites →https://doi.org/10.1080/15548627.2020.1839286openalex-extracted
Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3
inferredcites →https://doi.org/10.1111/acel.12709openalex-extracted
Autophagy controls mesenchymal stem cell properties and senescence during bone aging
inferredcites →https://doi.org/10.7150/thno.17949openalex-extracted
Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis
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