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Plasma Metabolomic Profiling as a Tool to Identify Predictive Biomarkers of Methotrexate Efficacy in Rheumatoid Arthritis
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Molecular cloning of the cDNA of mouse mitochondrial NADP-dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation.
inferredcites →https://doi.org/10.1002/(sici)1097-4644(19960301)60:3<400::aid-jcb11>3.0.co;2-oopenalex-snapshot
Molecular cloning of the cDNA of mouse mitochondrial NADP-dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation
inferredcites →https://doi.org/10.1002/0471142727.mb3004s114openalex-snapshot
Metabolomics by Gas Chromatography–Mass Spectrometry: Combined Targeted and Untargeted Profiling
inferredcites →https://doi.org/10.1002/1097-0142(1950)3:1<32::aid-cncr2820030106>3.0.co;2-3openalex-snapshot
Index for rating diagnostic tests
inferredcites →https://doi.org/10.1002/acr.24042openalex-snapshot
2019 Update of the American College of Rheumatology Recommended Rheumatoid Arthritis Disease Activity Measures
inferredcites →https://doi.org/10.1002/art.1780310302openalex-snapshot
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
inferredcites →https://doi.org/10.1002/art.24653openalex-snapshot
Determinants of red blood cell methotrexate polyglutamate concentrations in rheumatoid arthritis patients receiving long‐term methotrexate treatment
inferredcites →https://doi.org/10.1002/art.34498openalex-snapshot
A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: The Treatment of Early Aggressive Rheumatoid Arthritis trial
inferredcites →https://doi.org/10.1002/art.38113openalex-snapshot
Association of Low Baseline Levels of Erythrocyte Folate With Treatment Nonresponse at Three Months in Rheumatoid Arthritis Patients Receiving Methotrexate
inferredcites →https://doi.org/10.1002/art.41622openalex-snapshot
The Pretreatment Gut Microbiome Is Associated With Lack of Response to Methotrexate in New‐Onset Rheumatoid Arthritis
inferredcites →https://doi.org/10.1002/bms.1200131004openalex-snapshot
Urinary metabolites ofL-threonine in type 1 diabetes determined by combined gas chromatography/chemical ionization mass spectrometry
inferredcites →https://doi.org/10.1016/j.bmc.2017.08.031openalex-snapshot
Improving oral bioavailability of cyclic peptides by N-methylation
inferredcites →https://doi.org/10.1016/j.jpba.2016.02.004openalex-snapshot
Exploration of the serum metabolite signature in patients with rheumatoid arthritis using gas chromatography–mass spectrometry
inferredcites →https://doi.org/10.1016/j.nutres.2020.03.005openalex-snapshot
Human gut microbiome composition and tryptophan metabolites were changed differently by fast food and Mediterranean diet in 4 days: a pilot study
inferredcites →https://doi.org/10.1038/nrrheum.2016.1openalex-snapshot
Metabolomics in rheumatic diseases: desperately seeking biomarkers
inferredcites →https://doi.org/10.1093/oso/9780198509844.001.0001openalex-snapshot
The Statistical Evaluation of Medical Tests for Classification and Prediction
inferredcites →https://doi.org/10.1097/md.0000000000025481openalex-snapshot
Current smoking predicts inadequate response to methotrexate monotherapy in rheumatoid arthritis patients naïve to DMARDs
inferredcites →https://doi.org/10.1128/aac.9.2.224openalex-snapshot
Biogenetic Origin of the d -Isoleucine and N -Methyl- l -Alloisoleucine Residues in the Actinomycins
inferredcites →https://doi.org/10.1136/ard.2008.096487openalex-snapshot
Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies
inferredcites →https://doi.org/10.1186/s13075-018-1729-2openalex-snapshot
Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: insights from systems biology
inferredcites →https://doi.org/10.2105/ajph.89.5.731openalex-snapshot
Minor tobacco alkaloids as biomarkers for tobacco use: comparison of users of cigarettes, smokeless tobacco, cigars, and pipes.
inferredcites →https://doi.org/10.3390/cancers12102842openalex-snapshot
(2R,3S)-Dihydroxybutanoic Acid Synthesis as a Novel Metabolic Function of Mutant Isocitrate Dehydrogenase 1 and 2 in Acute Myeloid Leukemia
inferredcites →https://doi.org/10.3390/jpm10040271openalex-snapshot
Identification of Metabolic Biomarkers in Relation to Methotrexate Response in Early Rheumatoid Arthritis
inferredcites →https://doi.org/10.3390/metabo11120824openalex-snapshot
Plasma Metabolome Normalization in Rheumatoid Arthritis Following Initiation of Methotrexate and the Identification of Metabolic Biomarkers of Efficacy
inferredcites →https://doi.org/10.3390/metabo12010024openalex-snapshot
Methotrexate Disposition, Anti-Folate Activity, and Metabolomic Profiling to Identify Molecular Markers of Disease Activity and Drug Response in the Collagen-Induced Arthritis Mouse Model
inferredcites →https://doi.org/10.3390/metabo12030211openalex-snapshot
High-Throughput UHPLC-MS to Screen Metabolites in Feces for Gut Metabolic Health
inferredcites →https://doi.org/10.3390/metabo8020031openalex-snapshot
Software Tools and Approaches for Compound Identification of LC-MS/MS Data in Metabolomics
inferredcites →https://doi.org/10.3892/etm.2012.567openalex-snapshot
1H NMR-based metabolomic analysis for identifying serum biomarkers to evaluate methotrexate treatment in patients with early rheumatoid arthritis
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4764473openalex-extracted
Optimization of Metabolomics Pretreatment Method of Cholangiocarcinoma Cells Based on Ultrahigh Performance Liquid Chromatography Coupled with Mass Spectrometry
inferred← citeshttps://doi.org/10.2139/ssrn.4804410openalex-extracted
Optimization of Metabolomics Pretreatment Method of Cholangiocarcinoma Cells Based on Ultrahigh Performance Liquid Chromatography Coupled with Mass Spectrometry
inferred← citeshttps://doi.org/10.1002/jcsm.13240openalex-snapshot
Urinary metabolomic biomarker candidates for skeletal muscle wasting in patients with rheumatoid arthritis
inferred← citeshttps://doi.org/10.1007/978-981-97-4723-8_1openalex-snapshot
Introduction to Clinical Applications of Biomolecules in Disease Diagnosis
inferred← citeshttps://doi.org/10.1007/s10067-025-07355-6openalex-snapshot
Evaluating treatment responsiveness in rheumatoid arthritis through predictive metabolomic profiling: A systematic review of studies examining methotrexate, TNF, and IL-6 inhibitors as therapeutic interventions
inferred← citeshttps://doi.org/10.1016/bs.pmbts.2025.05.015openalex-snapshot
Biomarkers in wearables, ingestible, and implantable sensors for health monitoring
inferred← citeshttps://doi.org/10.1016/j.autrev.2025.103975openalex-snapshot
The metabolic landscape of connective tissue diseases: Applications and discoveries in metabolomics research
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118755openalex-snapshot
Plasma metabolic profiling identifies elevated hippurate as a potential biomarker of methotrexate non-response in juvenile idiopathic arthritis
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115436openalex-snapshot
Exploring the alleviating effect and mechanism of the diterpenoid alkaloid Polyschistine D on rheumatoid arthritis based on network pharmacology and non-targeted metabolomics
inferred← citeshttps://doi.org/10.1038/s41392-023-01399-3openalex-snapshot
Small molecule metabolites: discovery of biomarkers and therapeutic targets
inferred← citeshttps://doi.org/10.1080/08820139.2024.2381078openalex-snapshot
Characteristics of T-Cell Receptor Repertoire for Differential Response to Methotrexate Treatment for Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.2147/oarrr.s372610openalex-snapshot
Towards Personalized Medicine in Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.3389/fphar.2026.1970975openalex-snapshot
Predictive biomarkers for precision treatment in rheumatoid arthritis: are we there yet?
inferred← citeshttps://doi.org/10.3390/futurepharmacol2040038openalex-snapshot
Metabolomic Profiling of Red Blood Cells to Identify Molecular Markers of Methotrexate Response in the Collagen Induced Arthritis Mouse Model
inferred← citeshttps://doi.org/10.3390/metabo15110715openalex-snapshot
Predictive Biomarkers of Methotrexate Treatment Response in Patients with Rheumatoid Arthritis: A Systematic Review
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