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Design, Development and Evaluation of Prodrug-Type TrkA-Selective Inhibitor with Antinociceptive Effects In Vivo

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inferredcites →https://doi.org/10.1007/978-0-387-49785-3_20openalex-extracted
Prodrugs of Carboxylic Acids
inferredcites →https://doi.org/10.1007/978-1-61779-536-7_1openalex-extracted
The Neurotrophin Family of Neurotrophic Factors: An Overview
inferredcites →https://doi.org/10.1007/s102860200016openalex-extracted
Genetics of congenital insensitivity to pain with anhidrosis (CIPA) or hereditary sensory and autonomic neuropathy type IV. Clinical, biological and molecular aspects of mutations in TRKA(NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor.
inferredcites →https://doi.org/10.1016/0014-5793(93)81580-sopenalex-extracted
Nucleoside analogues previously found to be inactive against HIV may be activated by simple chemical phosphorylation
inferredcites →https://doi.org/10.1016/j.chembiol.2009.05.010openalex-extracted
Amitriptyline is a TrkA and TrkB Receptor Agonist that Promotes TrkA/TrkB Heterodimerization and Has Potent Neurotrophic Activity
inferredcites →https://doi.org/10.1016/j.pharmthera.2015.10.002openalex-extracted
Allosteric small-molecule kinase inhibitors
inferredcites →https://doi.org/10.1016/j.tins.2013.12.002openalex-extracted
Opening paths to novel analgesics: the role of potassium channels in chronic pain
inferredcites →https://doi.org/10.1016/j.tips.2005.12.001openalex-extracted
Novel class of pain drugs based on antagonism of NGF
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b00964openalex-extracted
Targeting the Nerve Growth Factor (NGF) Pathway in Drug Discovery. Potential Applications to New Therapies for Chronic Pain
inferredcites →https://doi.org/10.1021/acs.jmedchem.8b00280openalex-extracted
Discovery of Allosteric, Potent, Subtype Selective, and Peripherally Restricted TrkA Kinase Inhibitors
inferredcites →https://doi.org/10.1021/acschembio.9b00126openalex-extracted
Deciphering the Allosteric Binding Mechanism of the Human Tropomyosin Receptor Kinase A (hTrkA) Inhibitors
inferredcites →https://doi.org/10.1038/aps.2016.33openalex-extracted
Activation of neuronal Kv7/KCNQ/M-channels by the opener QO58-lysine and its anti-nociceptive effects on inflammatory pain in rodents
inferredcites →https://doi.org/10.1038/nn1336openalex-extracted
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay
inferredcites →https://doi.org/10.1038/s41571-018-0113-0openalex-extracted
NTRK fusion-positive cancers and TRK inhibitor therapy
inferredcites →https://doi.org/10.1039/c2md20180aopenalex-extracted
Approaches to discover non-ATP site kinase inhibitors
inferredcites →https://doi.org/10.1039/c5cc08714gopenalex-extracted
A mild hydration of nitriles catalysed by copper( ii ) acetate
inferredcites →https://doi.org/10.1073/pnas.0611253104openalex-extracted
The function neutralizing anti-TrkA antibody MNAC13 reduces inflammatory and neuropathic pain
inferredcites →https://doi.org/10.1073/pnas.1611577114openalex-extracted
Structural characterization of nonactive site, TrkA-selective kinase inhibitors
inferredcites →https://doi.org/10.1083/jcb.122.2.443openalex-extracted
Neurotrophin-3 induced by tri-iodothyronine in cerebellar granule cells promotes Purkinje cell differentiation
inferredcites →https://doi.org/10.1093/bja/aet123openalex-extracted
Chronic pain epidemiology and its clinical relevance
inferredcites →https://doi.org/10.1126/scisignal.2003203openalex-extracted
Elucidating Human Phosphatase-Substrate Networks
inferredcites →https://doi.org/10.1128/aac.6.5.563openalex-extracted
Clinical Pharmacology of Pivampicillin
inferredcites →https://doi.org/10.2165/11630080-000000000-00000openalex-extracted
Adverse Effects Associated with Non-opioid and Opioid Treatment in Patients with Chronic Pain
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