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Biomimetic Ion Channel Shortens QT Interval of Type 2 Long QT Syndrome Through Efficient Transmembrane Transport of Potassium Ions

https://doi.org/10.2139/ssrn.4642313
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Highly Selective Transmembrane Transport of Exogenous Lithium Ions through Rationally Designed Supramolecular Channels
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Pyridine/Oxadiazole‐Based Helical Foldamer Ion Channels with Exceptionally High K+/Na+ Selectivity
inferredcites →https://doi.org/10.1002/anie.202214194openalex-extracted
Highly Selective Transmembrane Transport of Exogenous Lithium Ions through Rationally Designed Supramolecular Channels
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The conduction velocity-potassium relationship in the heart is modulated by sodium and calcium
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Role of slow delayed rectifying potassium current in dynamics of repolarization and electrical memory in swine ventricles
inferredcites →https://doi.org/10.1016/0002-8703(85)90626-xopenalex-extracted
Idiopathic long QT syndrome: Progress and questions
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Highlights for the 6th International Ion Channel Conference: ion channel structure, function, disease and therapeutics
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Defective protein trafficking in hERG-associated hereditary long QT syndrome (LQT2): molecular mechanisms and restoration of intracellular protein processing
inferredcites →https://doi.org/10.1016/j.cell.2019.12.003openalex-extracted
Structural Basis of Human KCNQ1 Modulation and Gating
inferredcites →https://doi.org/10.1016/j.ejphar.2003.12.017openalex-extracted
Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic β-cells
inferredcites →https://doi.org/10.1016/j.ejphar.2021.174441openalex-extracted
Mechanisms of gefitinib-induced QT prolongation
inferredcites →https://doi.org/10.1016/j.yjmcc.2018.01.009openalex-extracted
Restoration of mutant hERG stability by inhibition of HDAC6
inferredcites →https://doi.org/10.1016/s1054-3589(10)59004-5openalex-extracted
Pharmacology of Cardiac Potassium Channels
inferredcites →https://doi.org/10.1021/acs.nanolett.0c00567openalex-extracted
Highly Efficient Exclusion of Alkali Metal Ions via Electrostatic Repulsion Inside Positively Charged Channels
inferredcites →https://doi.org/10.1021/jacs.0c12128openalex-extracted
Foldamer-Based Potassium Channels with High Ion Selectivity and Transport Activity
inferredcites →https://doi.org/10.1021/jo052222ropenalex-extracted
Phenanthroline Dicarboxamide-Based Helical Foldamers: Stable Helical Structures in Methanol
inferredcites →https://doi.org/10.1038/sj.npp.1300844openalex-extracted
Inhibition of G Protein-Activated Inwardly Rectifying K+ Channels by Ifenprodil
inferredcites →https://doi.org/10.1093/cvr/28.6.762openalex-extracted
Role of ATP sensitive potassium channel in extracellular potassium accumulation and cardiac arrhythmias during myocardial ischaemia
inferredcites →https://doi.org/10.1093/eurheartj/ehv316openalex-extracted
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
inferredcites →https://doi.org/10.1093/hmg/ddl230openalex-extracted
C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3ϵ
inferredcites →https://doi.org/10.1097/00005344-199103000-00018openalex-extracted
Effects of the New Class III Antiarrhythmic Drug E-4031 on Myocardial Contractility and Electrophysiological Parameters
inferredcites →https://doi.org/10.1097/fjc.0b013e31817dd013openalex-extracted
In Vivo Effects of the IKr Agonist NS3623 on Cardiac Electrophysiology of the Guinea Pig
inferredcites →https://doi.org/10.1097/fjc.0b013e3181bfb17copenalex-extracted
Clobutinol Delays Ventricular Repolarization in the Guinea Pig Heart: Comparison With Cardiac Effects of hERG K+ Channel Inhibitor E-4031
inferredcites →https://doi.org/10.1111/apha.13471openalex-extracted
Polyunsaturated fatty acid‐derived IKs channel activators shorten the QT interval ex‐vivo and in‐vivo
inferredcites →https://doi.org/10.1111/nyas.14425openalex-extracted
Targeting the β‐adrenergic receptor in the clinical management of congenital long QT syndrome
inferredcites →https://doi.org/10.1126/science.2305257openalex-extracted
Glucose, Sulfonylureas, and Neurotransmitter Release: Role of ATP-Sensitive K + Channels
inferredcites →https://doi.org/10.1136/heartjnl-2020-318259openalex-extracted
Diagnosis, management and therapeutic strategies for congenital long QT syndrome
inferredcites →https://doi.org/10.1152/physrev.00002.2005openalex-extracted
Molecular Physiology of Cardiac Repolarization
inferredcites →https://doi.org/10.1161/01.cir.101.6.616openalex-extracted
Effectiveness and Limitations of β-Blocker Therapy in Congenital Long-QT Syndrome
inferredcites →https://doi.org/10.1161/01.cir.88.2.782openalex-extracted
Diagnostic criteria for the long QT syndrome. An update.
inferredcites →https://doi.org/10.1161/circulationaha.108.772533openalex-extracted
High Efficacy of β-Blockers in Long-QT Syndrome Type 1
inferredcites →https://doi.org/10.1177/1074248417729880openalex-extracted
Cardiac Potassium Channels: Physiological Insights for Targeted Therapy
inferredcites →https://doi.org/10.5603/kp.2015.0190openalex-extracted
2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
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