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Depp1 Emerges as a Prognostic Biomarker Associated with Stroma-Rich and Immunosuppressive Microenvironment and Predicts Poor Chemotherapy Response in Gastric Cancer

https://doi.org/10.2139/ssrn.4644577
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1 of the 47 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1158/1541-7786.mcr-19-0077 (notice 2024-11-01).

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Metabolic programming and immune suppression in the tumor microenvironment
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The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
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Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression
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Hallmarks of Cancer: The Next Generation
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The Molecular Signatures Database Hallmark Gene Set Collection
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Multiple roles of lymphatic vessels in tumor progression
inferredcites →https://doi.org/10.1016/s0140-6736(20)31288-5openalex-extracted
Gastric cancer
inferredcites →https://doi.org/10.1016/s1016-8478(23)07329-6openalex-extracted
Meta- and Gene Set Analysis of Stomach Cancer Gene Expression Data
inferredcites →https://doi.org/10.1016/s1470-2045(14)71116-7openalex-extracted
Nomograms in oncology: more than meets the eye
inferredcites →https://doi.org/10.1023/a:1008243606668openalex-extracted
Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer
inferredcites →https://doi.org/10.1038/ncomms3612openalex-extracted
Inferring tumour purity and stromal and immune cell admixture from expression data
inferredcites →https://doi.org/10.1038/nrdp.2017.36openalex-extracted
Gastric adenocarcinoma
inferredcites →https://doi.org/10.1038/s41392-021-00484-9openalex-extracted
Targeting tumor-associated macrophages to synergize tumor immunotherapy
inferredcites →https://doi.org/10.1038/s41392-022-01190-wopenalex-extracted
Signaling pathways and therapeutic interventions in gastric cancer
inferredcites →https://doi.org/10.1038/s41392-023-01332-8openalex-extracted
Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions
inferredcites →https://doi.org/10.1038/s41419-017-0223-0openalex-extracted
Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling
inferredcites →https://doi.org/10.1038/s41467-018-04179-8openalex-extracted
Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype
inferredcites →https://doi.org/10.1038/s41571-021-00546-5openalex-extracted
Clinical and therapeutic relevance of cancer-associated fibroblasts
inferredcites →https://doi.org/10.1038/s41571-022-00620-6openalex-extracted
Clinical relevance of tumour-associated macrophages
inferredcites →https://doi.org/10.1038/s41571-023-00747-0openalex-extracted
Global burden of gastric cancer: epidemiological trends, risk factors, screening and prevention
inferredcites →https://doi.org/10.1038/s41577-022-00694-4openalex-extracted
Immunomodulation by endothelial cells — partnering up with the immune system?
inferredcites →https://doi.org/10.1038/s41580-018-0080-4openalex-extracted
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
inferredcites →https://doi.org/10.1038/s41591-018-0022-xopenalex-extracted
Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition
inferredcites →https://doi.org/10.1056/nejmoa055531openalex-extracted
Perioperative Chemotherapy versus Surgery Alone for Resectable Gastroesophageal Cancer
inferredcites →https://doi.org/10.1089/omi.2011.0118openalex-extracted
clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters
inferredcites →https://doi.org/10.1093/bib/bbab108openalex-extracted
Venn diagrams in bioinformatics
inferredcites →https://doi.org/10.1093/bib/bbab260openalex-extracted
oncoPredict: an R package for predicting in vivo or cancer patient drug response and biomarkers from cell line screening data
inferredcites →https://doi.org/10.1093/bioinformatics/btq064openalex-extracted
GOSemSim: an R package for measuring semantic similarity among GO terms and gene products
inferredcites →https://doi.org/10.1093/molehr/gah186openalex-extracted
A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor
inferredcites →https://doi.org/10.1093/nar/gkv007openalex-extracted
limma powers differential expression analyses for RNA-sequencing and microarray studies
inferredcites →https://doi.org/10.1111/apm.1965.64.1.31openalex-extracted
THE TWO HISTOLOGICAL MAIN TYPES OF GASTRIC CARCINOMA: DIFFUSE AND SO‐CALLED INTESTINAL‐TYPE CARCINOMA
inferredcites →https://doi.org/10.1111/j.1365-2559.2008.03021.xopenalex-extracted
EGFR in gastric carcinomas: prognostic significance of protein overexpression and high gene copy number
inferredcites →https://doi.org/10.1158/0008-5472.can-17-0307openalex-extracted
TIMER: A Web Server for Comprehensive Analysis of Tumor-Infiltrating Immune Cells
inferredcites →https://doi.org/10.1158/1541-7786.mcr-19-0077openalex-extracted
RETRACTED: KRAS Activation in Gastric Adenocarcinoma Stimulates Epithelial-to-Mesenchymal Transition to Cancer Stem–Like Cells and Promotes Metastasis
inferredcites →https://doi.org/10.1158/2159-8290.cd-17-1260openalex-extracted
Targeted Therapies for Targeted Populations: Anti-EGFR Treatment for EGFR -Amplified Gastroesophageal Adenocarcinoma
inferredcites →https://doi.org/10.1186/1476-4598-13-224openalex-extracted
C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma
inferredcites →https://doi.org/10.1186/s10020-022-00468-7openalex-extracted
The dynamic alteration of transcriptional regulation by crucial TFs during tumorigenesis of gastric cancer
inferredcites →https://doi.org/10.1186/s12885-020-06814-4openalex-extracted
Deconvolution of diffuse gastric cancer and the suppression of CD34 on the BALB/c nude mice model
inferredcites →https://doi.org/10.1186/s13045-023-01451-3openalex-extracted
Gastric cancer treatment: recent progress and future perspectives
inferredcites →https://doi.org/10.1186/s13073-019-0638-6openalex-extracted
Molecular and pharmacological modulators of the tumor immune contexture revealed by deconvolution of RNA-seq data
inferredcites →https://doi.org/10.1186/s40880-018-0337-5openalex-extracted
Proposal and validation of a modified staging system to improve the prognosis predictive performance of the 8th AJCC/UICC pTNM staging system for gastric adenocarcinoma: a multicenter study with external validation
inferredcites →https://doi.org/10.1200/jco.2007.12.9791openalex-extracted
How To Build and Interpret a Nomogram for Cancer Prognosis
inferredcites →https://doi.org/10.1200/jco.2014.55.2208openalex-extracted
Moving Beyond the Hazard Ratio in Quantifying the Between-Group Difference in Survival Analysis
inferredcites →https://doi.org/10.1200/jco.21.02745openalex-extracted
Integration of Genomic Biology Into Therapeutic Strategies of Gastric Cancer Peritoneal Metastasis
inferredcites →https://doi.org/10.1371/journal.pgen.1000676openalex-extracted
Oncogenic Pathway Combinations Predict Clinical Prognosis in Gastric Cancer
inferredcites →https://doi.org/10.3389/fonc.2023.1175958openalex-extracted
Anti-HPV16 oncoproteins siRNA therapy for cervical cancer using a novel transdermal peptide PKU12
inferredcites →https://doi.org/10.7554/elife.26476openalex-extracted
Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data
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