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Effects of Voluntary or Regular Exercise in Adolescent Male Rats Exposed to Chronic Social Isolation on Cognitive Functions, Anxiety, and Neurotrophic Factors

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Cognitive dysfunction and epigenetic alterations of the BDNF gene are induced by social isolation during early adolescence
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Effect of aerobic exercise on BDNF/proBDNF expression in the ischemic hippocampus and depression recovery of rats after stroke
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An overview of the currency and usefulness of behavioral tests used from past to present to assess anxiety, social behavior and depression in rats and mice
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Long term treadmill exercise performed to chronic social isolated rats regulate anxiety behavior without improving learning
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Behavioural and neurochemical effects of post-weaning social isolation in rodents—Relevance to developmental neuropsychiatric disorders
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Positive effects of aerobic exercise on learning and memory functioning, which correlate with hippocampal IGF-1 increase in adolescent rats
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The effect of mild stress stimulation on the nerve growth factor (NGF) and tyrosine kinase receptor A (TrkA) immunoreactivity in the paraventricular nucleus (PVN) of the hypothalamus and hippocampus in aged vs. adult rats
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Neurogenesis decreases during brain maturation from adolescence to adulthood
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Animal models of major depression and their clinical implications
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Effects of environmental enrichment and voluntary exercise on neurogenesis, learning and memory, and pattern separation: BDNF as a critical variable?
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Puberty and adolescence as a time of vulnerability to stressors that alter neurobehavioral processes
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The effects of social deprivation on adolescent development and mental health
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Developmental changes in hypothalamus–pituitary–adrenal activity over the transition to adolescence: Normative changes and associations with puberty
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From normal fear to pathological anxiety.
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Anticipation of rewarding electrical brain stimulation evokes ultrasonic vocalization in rats.
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The role of voluntary exercise in enriched rearing: A behavioral analysis.
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Maternal care, isolation-induced infant ultrasonic calling, and their relations to adult anxiety-related behavior in the rat.
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Loneliness as a specific risk factor for depressive symptoms: Cross-sectional and longitudinal analyses.
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Neural consequences of enviromental enrichment
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Neurotrophin signalling in health and disease
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Dose dependent effects of oxytocin on cognitive defects and anxiety disorders in adult rats following acute infantile maternal deprivation stress
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Postacute Ischemia Vascular Endothelial Growth Factor Transfer by Transferrin-Targeted Liposomes Attenuates Ischemic Brain Injury After Experimental Stroke in Rats
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Environmental Change, the Stress Response, and Neurogenesis: Fig. 1
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Cognitive benefit and cost of acute stress is differentially modulated by individual brain state
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Differential roles for hippocampal areas CA1 and CA3 in the contextual encoding and retrieval of extinguished fear
inferredcites →https://doi.org/10.1111/j.1749-6632.2011.06028.xopenalex-extracted
Social isolation
inferredcites →https://doi.org/10.1146/annurev-psych-010814-015240openalex-extracted
The Neuroendocrinology of Social Isolation
inferredcites →https://doi.org/10.1146/annurev.neuro.24.1.677openalex-extracted
Neurotrophins: Roles in Neuronal Development and Function
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Long-Term Potentiation and Memory
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Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
inferredcites →https://doi.org/10.1371/journal.pone.0124859openalex-extracted
Physical Exercise Enhances Cognitive Flexibility as Well as Astrocytic and Synaptic Markers in the Medial Prefrontal Cortex
inferredcites →https://doi.org/10.1517/14740338.2016.1140743openalex-extracted
Long-term side effects of glucocorticoids
inferredcites →https://doi.org/10.1523/jneurosci.2335-09.2009openalex-extracted
The Structural Integrity of an Amygdala–Prefrontal Pathway Predicts Trait Anxiety
inferredcites →https://doi.org/10.1523/jneurosci.2577-05.2005openalex-extracted
Depression of Synaptic Transmission by Vascular Endothelial Growth Factor in Adult Rat Hippocampus and Evidence for Increased Efficacy after Chronic Seizures
inferredcites →https://doi.org/10.1530/ec-16-0100openalex-extracted
The role of glucocorticoids and corticotropin-releasing hormone regulation on anxiety symptoms and response to treatment
inferredcites →https://doi.org/10.18699/vj21.025openalex-extracted
The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response
inferredcites →https://doi.org/10.30621/jbachs.1017172openalex-extracted
Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals
inferredcites →https://doi.org/10.3109/10520295.2013.825318openalex-extracted
Effects of exercise and poor indoor air quality on learning, memory and blood IGF-1 in adolescent mice
inferredcites →https://doi.org/10.3109/10520295.2014.946968openalex-extracted
Effects of voluntary and involuntary exercise on cognitive functions, and VEGF and BDNF levels in adolescent rats
inferredcites →https://doi.org/10.5604/20831862.1132130openalex-extracted
Swimming exercise increases neurogenesis in the subventricular zone, and upregulates NGF and Synapsin I level in the olfactory bulb of the adult rats
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