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A Multi-Omics Approach for Understanding Blood Digestion Dynamics in Ixodes Scapularis and Identification of Anti-Tick Vaccine Targets

https://doi.org/10.2139/ssrn.4745251
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Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
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RNA-seq analysis of the salivary glands and midgut of the Argasid tick Ornithodoros rostratus
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Localization of vitellogenin production in the blacklegged tick,Ixodes scapularis(Acari: Ixodidae)
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Salp25D, anIxodes scapularisAntioxidant, Is 1 of 14 Immunodominant Antigens in Engorged Tick Salivary Glands
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The Sequence Alignment/Map format and SAMtools
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Ixolaris binding to factor X reveals a precursor state of factor Xa heparin‐binding exosite
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Transcriptional activities of two newly identified Haemaphysalis longicornis tick‐derived promoter regions in the Ixodes scapularis tick cell line (ISE6)
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The crystal structures of two salivary cystatins from the tick Ixodes scapularis and the effect of these inhibitors on the establishment of Borrelia burgdorferi infection in a murine model
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Antithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade
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Understanding the evolutionary structural variability and target specificity of tick salivary Kunitz peptides using next generation transcriptome data
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Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
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Insights into the development of Ixodes scapularis: a resource for research on a medically important tick species
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A repertoire of protease inhibitor families in Amblyomma americanum and other tick species: inter-species comparative analyses
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A proteomic insight into the midgut proteome of Ornithodoros moubata females reveals novel information on blood digestion in argasid ticks
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Characterization and expression analysis of a newly identified glutathione S-transferase of the hard tick Haemaphysalis longicornis during blood-feeding
inferredcites →https://doi.org/10.1186/s13071-018-2932-3openalex-extracted
Whole body transcriptomes and new insights into the biology of the tick Ixodes ricinus
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In silico selection of functionally important proteins from the mialome of Ornithodoros erraticus ticks and assessment of their protective efficacy as vaccine targets
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Proteomics informed by transcriptomics for a qualitative and quantitative analysis of the sialoproteome of adult Ornithodoros moubata ticks
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Hlcyst-1 and Hlcyst-2 are Potential Inhibitors of HlCPL-A in the Midgut of the Ixodid Tick Haemaphysalis longicornis
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Systems Biology of Tissue-Specific Response to Anaplasma phagocytophilum Reveals Differentiated Apoptosis in the Tick Vector Ixodes scapularis
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The serine protease homolog spheroide is involved in sensing of pathogenic Gram-positive bacteria
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Role of DUOX in gut inflammation: lessons from Drosophila model of gut-microbiota interactions
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Immunity-related genes in Ixodes scapularis—perspectives from genome information
inferredcites →https://doi.org/10.3389/fcimb.2017.00216openalex-extracted
Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction
inferredcites →https://doi.org/10.3389/fcimb.2017.00225openalex-extracted
A Dual Luciferase Reporter System for B. burgdorferi Measures Transcriptional Activity during Tick-Pathogen Interactions
inferredcites →https://doi.org/10.3389/fcimb.2017.00476openalex-extracted
Analysis of the Salivary Gland Transcriptome of Unfed and Partially Fed Amblyomma sculptum Ticks and Descriptive Proteome of the Saliva
inferredcites →https://doi.org/10.3389/fcimb.2020.00007openalex-extracted
A Peroxiredoxin From the Haemaphysalis longicornis Tick Affects Langat Virus Replication in a Hamster Cell Line
inferredcites →https://doi.org/10.3389/fmicb.2021.728996openalex-extracted
Virome and Blood Meal-Associated Host Responses in Ixodes persulcatus Naturally Fed on Patients
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Immunologic control of a parasitic arthropod. Identification of a protective antigen from Boophilus microplus.
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