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Elevated Brain-Derived Neurotrophic Factor Levels and Preserved Hippocampal Dendritic Spine Density Underlie the Rapid-Onset Antidepressant Effect of Extracts from Mallotus Oppositifolius

https://doi.org/10.2139/ssrn.4752205
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Safe African Medicinal Plants for Clinical Studies
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Cluster analysis reveals risk factors for repeated suicide attempts in a multi-ethnic Asian population
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Anti-inflammatory and anti-oxidant activities of Mallotus oppositifolius (Geisel) methanol leaf extracts
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Mouse strain differences in the unpredictable chronic mild stress: a four-antidepressant survey
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Critical role of brain-derived neurotrophic factor in mood disorders
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Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex
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The Role of AMPA receptor modulation in the treatment of neuropsychiatric diseases
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The long-lasting antidepressant effects of rapastinel (GLYX-13) are associated with a metaplasticity process in the medial prefrontal cortex and hippocampus
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Effects of ifenprodil on the antidepressant-like activity of NMDA ligands in the forced swim test in mice
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Antibacterial, anti-inflammatory and antimalarial activities of some Nigerian medicinal plants
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The hippocampus and depression
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The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?
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GLYX-13, a NMDA Receptor Glycine-Site Functional Partial Agonist, Induces Antidepressant-Like Effects Without Ketamine-Like Side Effects
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21st Century natural product research and drug development and traditional medicines
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Depression, antidepressants, and the shrinking hippocampus
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Inhibition of hippocampo-prefrontal cortex excitatory responses by the mesocortical DA system
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Depression in children and young people: identification and management in primary, community and secondary care (NICE guideline CG28)
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The Epidemiology of Depression Across Cultures
inferredcites →https://doi.org/10.1146/annurev.psych.48.1.191openalex-extracted
THE EFFECTS OF STRESSFUL LIFE EVENTS ON DEPRESSION
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Fine and distributed subcellular retinotopy of excitatory inputs to the dendritic tree of a collision-detecting neuron
inferredcites →https://doi.org/10.1155/2014/324063openalex-extracted
Antidepressant Effects ofMallotus oppositifoliusin Acute Murine Models
inferredcites →https://doi.org/10.1155/2017/7260130openalex-extracted
Brain-Derived Neurotrophic Factor, Depression, and Physical Activity: Making the Neuroplastic Connection
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Suicide Attempts Among Patients Starting Depression Treatment With Medications or Psychotherapy
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Chronic Depression
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Rapid Golgi Analysis Method for Efficient and Unbiased Classification of Dendritic Spines
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Structural MRI correlates for vulnerability and resilience to major depressive disorder
inferredcites →https://doi.org/10.1515/jbcpp-2015-0029openalex-extracted
Scientific evidence of plant with a rapid-onset and sustained antidepressant effect in a chronic model of depression: Mallotus oppositifolius
inferredcites →https://doi.org/10.1523/jneurosci.20-22-j0003.2000openalex-extracted
Essential Role of D1 But Not D2 Receptors in the NMDA Receptor-Dependent Long-Term Potentiation at Hippocampal-Prefrontal Cortex SynapsesIn Vivo
inferredcites →https://doi.org/10.1523/jneurosci.21-13-04915.2001openalex-extracted
Glutamatergic Afferents from the Hippocampus to the Nucleus Accumbens Regulate Activity of Ventral Tegmental Area Dopamine Neurons
inferredcites →https://doi.org/10.1523/jneurosci.3849-06.2007openalex-extracted
Acute Psychosocial Stress Reduces Cell Survival in Adult Hippocampal Neurogenesis without Altering Proliferation
inferredcites →https://doi.org/10.17226/25801openalex-extracted
Guide for the Care and Use of Laboratory Animals
inferredcites →https://doi.org/10.3389/fphar.2022.962549openalex-extracted
Extract of Mallotus oppositifolius (Geiseler) Müll. Arg. increased prefrontal cortex dendritic spine density and serotonin and attenuated para-chlorophenylalanine-aggravated aggressive and depressive behaviors in mice
inferredcites →https://doi.org/10.4088/jcp.v69n0610openalex-extracted
Rapid Onset of Antidepressant Action
inferredcites →https://doi.org/10.4103/0019-5545.58890openalex-extracted
Depression, suicidality and antidepressants: A coincidence?
inferredcites →https://doi.org/10.4103/0975-7406.183226openalex-extracted
Enhancement of inhibitory neurotransmission and inhibition of excitatory mechanisms underlie the anticonvulsant effects of Mallotus oppositifolius
inferredcites →https://doi.org/10.5567/pharmacologia.2012.683.692openalex-extracted
Screening of Central Effects of the Leaves of Mallotus oppositifolius (Geiseler) Mull. Arg. in Mice
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African indigenous plants with chemotherapeutic potentials and biotechnological approach to the production of bioactive prophylactic agents
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