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Intranasal Curcumin Improves Silica Induced Oxidative Lung Damage and Fibrosis Via Nrf-2/Keap-1 Pathway and Mitophagy

https://doi.org/10.2139/ssrn.4761569
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inferredcites →https://doi.org/10.1002/biof.1175openalex-extracted
Curcumin improves hypoxia induced dysfunctions in 3T3‐L1 adipocytes by protecting mitochondria and down regulating inflammation
inferredcites →https://doi.org/10.1002/jcp.24307openalex-extracted
Decreased expression of autophagic beclin 1 protein in idiopathic pulmonary fibrosis fibroblasts
inferredcites →https://doi.org/10.1002/tox.23124openalex-extracted
Silica dust exposure induces pulmonary fibrosis through autophagy signaling
inferredcites →https://doi.org/10.1007/s00204-010-0511-2openalex-extracted
Comparative effects of curcumin and resveratrol on aflatoxin B1-induced liver injury in rats
inferredcites →https://doi.org/10.1007/s10495-012-0798-yopenalex-extracted
Silica phagocytosis causes apoptosis and necrosis by different temporal and molecular pathways in alveolar macrophages
inferredcites →https://doi.org/10.1007/s12035-014-8705-xopenalex-extracted
The Glutathione System: A New Drug Target in Neuroimmune Disorders
inferredcites →https://doi.org/10.1016/j.cyto.2022.155949openalex-extracted
Protective effects of intranasal curcumin on silica-induced lung damage
inferredcites →https://doi.org/10.1016/j.ebiom.2019.07.063openalex-extracted
Mitochondrial dysfunction in human primary alveolar type II cells in emphysema
inferredcites →https://doi.org/10.1016/j.envpol.2006.08.013openalex-extracted
The antioxidative response system in Glycine max (L.) Merr. exposed to Deltamethrin, a synthetic pyrethroid insecticide
inferredcites →https://doi.org/10.1016/j.molmed.2004.09.003openalex-extracted
Nrf2–Keap1 defines a physiologically important stress response mechanism
inferredcites →https://doi.org/10.1016/j.neuroscience.2011.12.053openalex-extracted
Exercise induces mitochondrial biogenesis after brain ischemia in rats
inferredcites →https://doi.org/10.1016/j.redox.2019.101148openalex-extracted
Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice
inferredcites →https://doi.org/10.1016/j.taap.2021.115861openalex-extracted
Intranasal curcumin and dexamethasone combination ameliorates inflammasome (NLRP3) activation in lipopolysachharide exposed asthma exacerbations
inferredcites →https://doi.org/10.1016/s0021-9258(18)68680-6openalex-extracted
H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.
inferredcites →https://doi.org/10.1016/s0021-9258(18)71480-4openalex-extracted
SV40-transformed Human Lung Fibroblasts Secrete a 92-kDa Type IV Collagenase Which Is Identical to That Secreted by Normal Human Macrophages
inferredcites →https://doi.org/10.1016/s1086-5802(16)31126-3openalex-extracted
Antioxidant Nutrients: Current Dietary Recommendations and Research Update
inferredcites →https://doi.org/10.1038/cdd.2012.81openalex-extracted
The pathways of mitophagy for quality control and clearance of mitochondria
inferredcites →https://doi.org/10.1038/s41401-021-00693-6openalex-extracted
Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages
inferredcites →https://doi.org/10.1038/s41586-020-2938-9openalex-extracted
Fibrosis: from mechanisms to medicines
inferredcites →https://doi.org/10.1042/bj20021619openalex-extracted
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element
inferredcites →https://doi.org/10.1073/pnas.2008006117openalex-extracted
Nearly free surface silanols are the critical molecular moieties that initiate the toxicity of silica particles
inferredcites →https://doi.org/10.1074/jbc.m111.308460openalex-extracted
Autophagy Promotes Intracellular Degradation of Type I Collagen Induced by Transforming Growth Factor (TGF)-β1
inferredcites →https://doi.org/10.1080/15548627.2021.1997052openalex-extracted
AMBRA1 regulates mitophagy by interacting with ATAD3A and promoting PINK1 stability
inferredcites →https://doi.org/10.1093/carcin/20.5.911openalex-extracted
Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes
inferredcites →https://doi.org/10.1093/toxsci/kfh121openalex-extracted
Silica-Induced Apoptosis in Mouse Alveolar Macrophages Is Initiated by Lysosomal Enzyme Activity
inferredcites →https://doi.org/10.1097/01.mcp.0000152998.11335.24openalex-extracted
Basic pathogenetic mechanisms in silicosis: current understanding
inferredcites →https://doi.org/10.1111/all.14202openalex-extracted
Silica‐related diseases in the modern world
inferredcites →https://doi.org/10.1111/j.1742-7843.2005.pto_97103.xopenalex-extracted
Comparative Effects of Curcumin and an Analogue of Curcumin in Carbon Tetrachloride‐Induced Hepatotoxicity in Rats
inferredcites →https://doi.org/10.1111/resp.13695openalex-extracted
Silica‐associated lung disease: An old‐world exposure in modern industries
inferredcites →https://doi.org/10.1128/mcb.00099-20openalex-extracted
The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
inferredcites →https://doi.org/10.1146/annurev.pharmtox.46.120604.141046openalex-extracted
Cell Survival Responses to Environmental Stresses Via the Keap1-Nrf2-ARE Pathway
inferredcites →https://doi.org/10.1152/ajplung.00213.2012openalex-extracted
Insufficient autophagy in idiopathic pulmonary fibrosis
inferredcites →https://doi.org/10.1152/ajplung.00245.2005openalex-extracted
Induction of secondary apoptosis, inflammation, and lung fibrosis after intratracheal instillation of apoptotic cells in rats
inferredcites →https://doi.org/10.1155/2019/7090534openalex-extracted
Role of Nrf2 and Its Activators in Respiratory Diseases
inferredcites →https://doi.org/10.1155/2022/3769134openalex-extracted
Early Identification, Accurate Diagnosis, and Treatment of Silicosis
inferredcites →https://doi.org/10.1159/000457945openalex-extracted
Attenuation of Oxidative Stress-Induced Osteoblast Apoptosis by Curcumin is Associated with Preservation of Mitochondrial Functions and Increased Akt-GSK3β Signaling
inferredcites →https://doi.org/10.1161/circresaha.119.316007openalex-extracted
The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction
inferredcites →https://doi.org/10.1172/jci74942openalex-extracted
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
inferredcites →https://doi.org/10.1183/09031936.00205009openalex-extracted
Bone marrow-derived mononuclear cell therapy attenuates silica-induced lung fibrosis
inferredcites →https://doi.org/10.1191/0960327103ht411oaopenalex-extracted
Protective effect of curcumin against lead neurotoxicity in rat
inferredcites →https://doi.org/10.1371/journal.pone.0041394openalex-extracted
Autophagy in Idiopathic Pulmonary Fibrosis
inferredcites →https://doi.org/10.1371/journal.pone.0216711openalex-extracted
Curcumin attenuates oxidative stress in RAW264.7 cells by increasing the activity of antioxidant enzymes and activating the Nrf2-Keap1 pathway
inferredcites →https://doi.org/10.22037/ijpr.2019.1100749openalex-extracted
Anti-Inflammatory and Anti-Oxidative Effects of Myrtenol in the Rats with Allergic Asthma.
inferredcites →https://doi.org/10.3109/15376516.2013.879974openalex-extracted
N-acetylcysteine alleviated silica-induced lung fibrosis in rats by down-regulation of ROS and mitochondrial apoptosis signaling
inferredcites →https://doi.org/10.3390/cancers13010046openalex-extracted
The KEAP1–NRF2 System as a Molecular Target of Cancer Treatment
inferredcites →https://doi.org/10.3390/ijms22084162openalex-extracted
New Insights into Pathomechanisms and Treatment Possibilities for Lung Silicosis
inferredcites →https://doi.org/10.4049/jimmunol.1600265openalex-extracted
Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis
inferredcites →https://doi.org/10.5897/ajbr.9000127openalex-extracted
Glutathione S-transferase activity of erythrocyte genotypes HbAA, HbAS and HbSS in male volunteers administered with fansidar and quinine
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