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Design, Synthesis, Characterization, Molecular Docking Studies and Biological Evaluation of 5, 6, 7, 8-Tetrahydropyrido[3,4-D]Pyrimidine Derivatives as Antimicrobial Agents

https://doi.org/10.2139/ssrn.4789206
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inferredcites →https://doi.org/10.1002/cbdv.202300800openalex-extracted
Design, Synthesis of Novel 1,2,3‐Triazole Pendent Quinazolinones and Their Cytotoxicity against MCF‐7 Cell Line
inferredcites →https://doi.org/10.1002/jcc.21334openalex-extracted
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
inferredcites →https://doi.org/10.1007/978-1-4939-2269-7_19openalex-extracted
Small-Molecule Library Screening by Docking with PyRx
inferredcites →https://doi.org/10.1007/s10593-007-0100-3openalex-extracted
Synthesis of pyrido[3,4-d]pyrimidines by condensation of ethyl 1-benzyl-3-oxopiperidine-4-carboxylate with morpholine-4-carboxamidine
inferredcites →https://doi.org/10.1016/j.bioorg.2019.103390openalex-extracted
Design and synthesis of tetrahydropyridopyrimidine derivatives as dual GPR119 and DPP-4 modulators
inferredcites →https://doi.org/10.1016/j.bmcl.2014.04.068openalex-extracted
Discovery of 5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine inhibitors of Erk2
inferredcites →https://doi.org/10.1016/j.jscs.2014.06.007openalex-extracted
One-pot synthesis of pyrido[2,3-d]pyrimidine derivatives using sulfonic acid functionalized SBA-15 and the study on their antimicrobial activities
inferredcites →https://doi.org/10.1016/s0140-6736(21)02724-0openalex-extracted
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
inferredcites →https://doi.org/10.1016/s0966-842x(96)10085-8openalex-extracted
DNA gyrase as a drug target
inferredcites →https://doi.org/10.1021/acs.jmedchem.9b02052openalex-extracted
Identification of the Clinical Development Candidate MRTX849 , a Covalent KRASG12C Inhibitor for the Treatment of Cancer
inferredcites →https://doi.org/10.1021/acschemneuro.5b00304openalex-extracted
Substituted 5,6-(Dihydropyrido[3,4-d]pyrimidin-7(8H)-yl)-methanones as P2X7 Antagonists
inferredcites →https://doi.org/10.1021/acsmedchemlett.8b00382openalex-extracted
Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity
inferredcites →https://doi.org/10.1021/bi0159837openalex-extracted
DNA Gyrase Interaction with Coumarin-Based Inhibitors: The Role of the Hydroxybenzoate Isopentenyl Moiety and the 5‘-Methyl Group of the Noviose
inferredcites →https://doi.org/10.1021/jm301389hopenalex-extracted
Potent, Selective, and Orally Bioavailable Inhibitors of the Mammalian Target of Rapamycin Kinase Domain Exhibiting Single Agent Antiproliferative Activity
inferredcites →https://doi.org/10.1039/d3md00479aopenalex-extracted
Design, synthesis, and cytotoxicity of ibuprofen-appended benzoxazole analogues against human breast adenocarcinoma
inferredcites →https://doi.org/10.1177/2042098614554919openalex-extracted
Antimicrobial resistance: risk associated with antibiotic overuse and initiatives to reduce the problem
inferredcites →https://doi.org/10.2144/fsoa-2021-0012openalex-extracted
The COVID-19 Pandemic: a Threat to Antimicrobial Resistance Containment
inferredcites →https://doi.org/10.3389/bjbs.2023.11387openalex-extracted
Antimicrobial Resistance (AMR)
inferredcites →https://doi.org/10.3390/molecules25010091openalex-extracted
The Significance of Halogen Bonding in Ligand–Receptor Interactions: The Lesson Learned from Molecular Dynamic Simulations of the D4 Receptor
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