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Increased Calponin-3 Contributes to Epileptogenesis Through Astrocytes and Adenosine Metabolism

https://doi.org/10.2139/ssrn.4807172
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Pentylenetetrazol (PTZ) Kindling Model of Epilepsy
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Adenosine dysfunction in epilepsy
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Increased levels of acidic calponin during dendritic spine plasticity after pilocarpine‐induced seizures
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Purinergic signaling in epilepsy
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ENT1 Inhibition Attenuates Epileptic Seizure Severity Via Regulation of Glutamatergic Neurotransmission
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Adenosine Augmentation Evoked by an ENT1 Inhibitor Improves Memory Impairment and Neuronal Plasticity in the APP/PS1 Mouse Model of Alzheimer’s Disease
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Calponins: Adaptable modular regulators of the actin cytoskeleton
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The role of adenosine in epilepsy
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Adenosine augmentation therapies (AATs) for epilepsy: Prospect of cell and gene therapies
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Increased expression of calponin-3 in epileptic patients and experimental rats
inferredcites →https://doi.org/10.1016/j.gene.2016.02.040openalex-extracted
Calponin isoforms CNN 1, CNN 2 and CNN 3: Regulators for actin cytoskeleton functions in smooth muscle and non-muscle cells
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Neuroimaging and cognitive functions in temporal lobe epilepsy: A review of the literature
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The role of astrocytic glutamate transporters GLT-1 and GLAST in neurological disorders: Potential targets for neurotherapeutics
inferredcites →https://doi.org/10.1016/j.pneurobio.2021.102105openalex-extracted
ATP and adenosine—Two players in the control of seizures and epilepsy development
inferredcites →https://doi.org/10.1016/j.wneu.2022.06.136openalex-extracted
Calponin 3 Acts as a Potential Diagnostic and Prognostic Marker and Promotes Glioma Cell Proliferation, Migration, and Invasion
inferredcites →https://doi.org/10.1016/s0140-6736(14)60456-6openalex-extracted
Epilepsy: new advances
inferredcites →https://doi.org/10.1023/b:nere.0000013739.15160.a8openalex-extracted
Astrocytic Response in Hippocampus and Cerebral Cortex in an Experimental Epilepsy Model
inferredcites →https://doi.org/10.1038/s41401-023-01149-9openalex-extracted
Neuronal K+-Cl- cotransporter KCC2 as a promising drug target for epilepsy treatment
inferredcites →https://doi.org/10.1046/j.1528-1157.2001.10401.xopenalex-extracted
A Proposed Diagnostic Scheme for People with Epileptic Seizures and with Epilepsy: Report of the ILAE Task Force on Classification and Terminology
inferredcites →https://doi.org/10.1083/jcb.201902050openalex-extracted
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity
inferredcites →https://doi.org/10.1093/brain/awab145openalex-extracted
Cation leak underlies neuronal excitability in an HCN1 developmental and epileptic encephalopathy
inferredcites →https://doi.org/10.1093/brain/awh555openalex-extracted
Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation
inferredcites →https://doi.org/10.1111/epi.13709openalex-extracted
ILAE classification of the epilepsies: Position paper of the ILAE Commission for Classification and Terminology
inferredcites →https://doi.org/10.1111/j.1528-1157.1980.tb04305.xopenalex-extracted
Endogenously Released Adenosine Regulates Excitability in the In Vitro Hippocampus
inferredcites →https://doi.org/10.1111/j.1530-0277.2010.01187.xopenalex-extracted
ENT1 Regulates Ethanol‐Sensitive EAAT2 Expression and Function in Astrocytes
inferredcites →https://doi.org/10.1124/pr.112.006361openalex-extracted
Adenosine Kinase: Exploitation for Therapeutic Gain
inferredcites →https://doi.org/10.1126/sciadv.aau2357openalex-extracted
GPR40 modulates epileptic seizure and NMDA receptor function
inferredcites →https://doi.org/10.1126/science.aaa1299openalex-extracted
Targeting LDH enzymes with a stiripentol analog to treat epilepsy
inferredcites →https://doi.org/10.1136/bmj.2.1700.227openalex-extracted
The Neuroglia Elements in the Human Brain
inferredcites →https://doi.org/10.1172/jci122599openalex-extracted
TMEM25 modulates neuronal excitability and NMDA receptor subunit NR2B degradation
inferredcites →https://doi.org/10.1172/jci33737openalex-extracted
Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice
inferredcites →https://doi.org/10.1172/jci65636openalex-extracted
Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis
inferredcites →https://doi.org/10.1371/journal.pone.0201252openalex-extracted
Intestinal FXYD12 and sodium-potassium ATPase: A comparative study on two euryhaline medakas in response to salinity changes
inferredcites →https://doi.org/10.1523/jneurosci.1574-14.2015openalex-extracted
Reactive Astrogliosis Causes the Development of Spontaneous Seizures
inferredcites →https://doi.org/10.1523/jneurosci.4781-03.2004openalex-extracted
Overexpression of Adenosine Kinase in Epileptic Hippocampus Contributes to Epileptogenesis
inferredcites →https://doi.org/10.2174/156652413804486214openalex-extracted
Functions of S100 Proteins
inferredcites →https://doi.org/10.2174/156802611795347582openalex-extracted
Molecular Biology of Nucleoside Transporters and their Distributions and Functions in the Brain
inferredcites →https://doi.org/10.3389/fncel.2018.00152openalex-extracted
Nucleocytoplasmic p27Kip1 Export Is Required for ERK1/2-Mediated Reactive Astroglial Proliferation Following Status Epilepticus
inferredcites →https://doi.org/10.3389/fneur.2020.591690openalex-extracted
Astrocytes as Guardians of Neuronal Excitability: Mechanisms Underlying Epileptogenesis
inferredcites →https://doi.org/10.3389/fnins.2020.610898openalex-extracted
Equilibrative Nucleoside Transporters-1 Inhibitors Act as Anti-epileptic Agents by Inhibiting Glutamatergic Transmission
inferredcites →https://doi.org/10.3390/jcm10020280openalex-extracted
Serum Calponin 3 Levels in Patients with Systemic Sclerosis: Possible Association with Skin Sclerosis and Arthralgia
inferredcites →https://doi.org/10.3791/56573openalex-extracted
Pentylenetetrazole-Induced Kindling Mouse Model
inferredcites →https://doi.org/10.3791/56573-vopenalex-extracted
Pentylenetetrazole-Induced Kindling Mouse Model
inferredcites →https://doi.org/10.3892/ol.2021.12895openalex-extracted
Calponin 3 suppresses proliferation, migration and invasion of non‑small cell lung cancer cells
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