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Protein Profile of Mouse Endolymph Extracts its Protective Role in Controlling the Cochlear Homeostasis

https://doi.org/10.2139/ssrn.4876614
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Drug‐induced ototoxicity: Mechanisms, Pharmacogenetics, and protective strategies
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Clusterin (Apolipoprotein J) Protein Levels Are Increased in Hippocampus and in Frontal Cortex in Alzheimer's Disease
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α2-Macroglobulin-Mediated Degradation of Amyloid β1–42: A Mechanism to Enhance Amyloid β Catabolism
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Sudden Sensorineural Hearing Loss
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Clusterin facilitates in vivo clearance of extracellular misfolded proteins
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Osteopontin: a new emerging role in psoriasis
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How is the highly positive endocochlear potential formed? The specific architecture of the stria vascularis and the roles of the ion-transport apparatus
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The unique electrical properties in an extracellular fluid of the mammalian cochlea; their functional roles, homeostatic processes, and pathological significance
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Comprehensive genetic testing in the clinical evaluation of 1119 patients with hearing loss
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Systemic Lipopolysaccharide Compromises the Blood-Labyrinth Barrier and Increases Entry of Serum Fluorescein into the Perilymph
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The role of osteopontin in inflammatory processes
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Silencing of Long Non-coding RNA GAS5 Suppresses Neuron Cell Apoptosis and Nerve Injury in Ischemic Stroke Through Inhibiting DNMT3B-Dependent MAP4K4 Methylation
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Ionic environment of cochlear hair cells
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Protein profiles of perilymph and endolymph of the guinea pig
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Contributions of mouse models to understanding of age- and noise-related hearing loss
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The multiple functions and mechanisms of osteopontin
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Protease‐activated alpha‐2‐macroglobulin can inhibit amyloid formation via two distinct mechanisms
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Expression of the carrier protein apolipoprotein D in the mouse inner ear
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Current concepts in age-related hearing loss: Epidemiology and mechanistic pathways
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An optimized, clinically relevant mouse model of cisplatin-induced ototoxicity
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Perilymph sampling from the cochlear apex: A reliable method to obtain higher purity perilymph samples from scala tympani
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APOE-amyloid interaction: Therapeutic targets
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TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia
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Dementia prevention, intervention, and care
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Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
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Gap junction systems in the mammalian cochlea
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Polymorphisms in the α-2 macroglobulin gene in psychogeriatric patients
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APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches
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Fetuin-A and Cystatin C Are Endogenous Inhibitors of Human Meprin Metalloproteases
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Serpin Structure, Mechanism, and Function
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Electric Field Effect on Phospholipid Monolayers at an Aqueous–Organic Liquid–Liquid Interface
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A comparative encyclopedia of DNA elements in the mouse genome
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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
inferredcites →https://doi.org/10.1038/s41598-022-22498-1openalex-snapshot
The LRP1/CD91 ligands, tissue-type plasminogen activator, α2-macroglobulin, and soluble cellular prion protein have distinct co-receptor requirements for activation of cell-signaling
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Alpha 2-macroglobulin acts as a clearance factor in the lysosomal degradation of extracellular misfolded proteins
inferredcites →https://doi.org/10.1056/nejmra1616601openalex-snapshot
Hearing Loss in Adults
inferredcites →https://doi.org/10.1073/pnas.0705102104openalex-snapshot
Electrochemical attosyringe
inferredcites →https://doi.org/10.1073/pnas.0711463105openalex-snapshot
The endocochlear potential depends on two K + diffusion potentials and an electrical barrier in the stria vascularis of the inner ear
inferredcites →https://doi.org/10.1073/pnas.162228299openalex-snapshot
Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease
inferredcites →https://doi.org/10.1080/01616412.2000.11740678openalex-snapshot
Apolipoprotein D in the aging brain and in Alzheimer’s dementia
inferredcites →https://doi.org/10.1080/19420862.2018.1518888openalex-snapshot
MHC-associated peptide proteomics enabling highly sensitive detection of immunogenic sequences for the development of therapeutic antibodies with low immunogenicity
inferredcites →https://doi.org/10.1096/fj.06-7986comopenalex-snapshot
The extracellular chaperone clusterin influences amyloid formation and toxicity by interacting with prefibrillar structures
inferredcites →https://doi.org/10.1097/00005537-199910000-00021openalex-snapshot
Cochlear Fluid Space Dimensions for Six Species Derived From Reconstructions of Three‐Dimensional Magnetic Resonance Images
inferredcites →https://doi.org/10.1111/cas.14756openalex-snapshot
Proteomics and phosphoproteomics reveal key regulators associated with cytostatic effect of amino acid transporter LAT1 inhibitor
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Expression of an inwardly rectifying K+ channel, Kir5.1, in specific types of fibrocytes in the cochlear lateral wall suggests its functional importance in the establishment of endocochlear potential
inferredcites →https://doi.org/10.1126/science.8346443openalex-snapshot
Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families
inferredcites →https://doi.org/10.1136/jmg.37.1.41openalex-snapshot
Prevalent connexin 26 gene (GJB2) mutations in Japanese
inferredcites →https://doi.org/10.1152/jn.1959.22.2.149openalex-snapshot
STRIA VASCULARIS AS SOURCE OF ENDOCOCHLEAR POTENTIAL
inferredcites →https://doi.org/10.1155/2013/615745openalex-snapshot
Elevated Osteopontin Levels in Mild Cognitive Impairment and Alzheimer’s Disease
inferredcites →https://doi.org/10.1155/2021/9979157openalex-snapshot
Deletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity
inferredcites →https://doi.org/10.1159/000027753openalex-snapshot
Development of Monovalent Ions in the Endolymph in Mouse Cochlea
inferredcites →https://doi.org/10.1159/000045707openalex-snapshot
Antiproteases and Cells in the Pathogenesis of β2-Microglobulin Amyloidosis: Role of α2-Macroglobulin and Macrophages
inferredcites →https://doi.org/10.1254/jphs.12124fpopenalex-snapshot
Establishment of Stable Cell Lines With High Expression of Heterodimers of Human 4F2hc and Human Amino Acid Transporter LAT1 or LAT2 and Delineation of Their Differential Interaction With ^|^alpha;-Alkyl Moieties
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Apolipoproteins: metabolic role and clinical biochemistry applications
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Osteopontin in Bone Metabolism and Bone Diseases
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Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
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Short-chain fatty acids bind to apoptosis-associated speck-like protein to activate inflammasome complex to prevent Salmonella infection
inferredcites →https://doi.org/10.1517/14728214.2011.552427openalex-snapshot
Emerging treatments for noise-induced hearing loss
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An ATP-Dependent Inwardly Rectifying Potassium Channel, KAB-2 (Kir4.1), in Cochlear Stria Vascularis of Inner Ear: Its Specific Subcellular Localization and Correlation with the Formation of Endocochlear Potential
inferredcites →https://doi.org/10.1530/joe-17-0453openalex-snapshot
Clusterin deficiency induces lipid accumulation and tissue damage in kidney
inferredcites →https://doi.org/10.21769/bioprotoc.3349openalex-snapshot
Photoaffinity Labeling of Respiratory Complex I in Bovine Heart Submitochondrial Particles by Photoreactive [125I] amilorides
inferredcites →https://doi.org/10.26508/lsa.202201887openalex-snapshot
Apolipoprotein E intersects with amyloid-β within neurons
inferredcites →https://doi.org/10.3109/00016488409107555openalex-snapshot
Effects of Pure Tone on Endocochlear Potential and Potassium Ion Concentration in the Guinea Pig Cochlea
inferredcites →https://doi.org/10.3109/03008208909002412openalex-snapshot
The Nature and Significance of Osteopontin
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Modulation of Amyloid-β1–40 Transport by ApoA1 and ApoJ Across an in vitro Model of the Blood-Brain Barrier
inferredcites →https://doi.org/10.3389/fnmol.2017.00300openalex-snapshot
Hearing Loss Controlled by Optogenetic Stimulation of Nonexcitable Nonglial Cells in the Cochlea of the Inner Ear
inferredcites →https://doi.org/10.3389/fnmol.2018.00356openalex-snapshot
Cell-Specific Transcriptome Analysis Shows That Adult Pillar and Deiters' Cells Express Genes Encoding Machinery for Specializations of Cochlear Hair Cells
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Osteopontin as a Link between Inflammation and Cancer: The Thorax in the Spotlight
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The Complement System, Aging, and Aging-Related Diseases
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