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Modulation of Iron Metabolism by New Chemicals Interacting with the Iron Regulatory System

https://doi.org/10.2139/ssrn.4960121
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Chloroacetamide Herbicides
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Thyroid endocrine disruption of acetochlor on zebrafish (Danio rerio) larvae
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Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
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Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
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Stereoselective induction of developmental toxicity and immunotoxicity by acetochlor in the early life stage of zebrafish
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Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis
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Cisplatin in cancer therapy: Molecular mechanisms of action
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Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review
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Deferasirox exposure induces reactive oxygen species and reduces growth and viability of myelodysplastic hematopoietic progenitors
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The formation and biological significance of N7-guanine adducts
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Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease
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Reactive chemistry for covalent probe and therapeutic development
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Specific interactions of chloroacetanilide herbicides with human ABC transporter proteins
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Environmental Electrophiles: Protein Adducts, Modulation of Redox Signaling, and Interaction with Persulfides/Polysulfides
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Chemoproteomic Profiling of Acetanilide Herbicides Reveals Their Role in Inhibiting Fatty Acid Oxidation
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High-Throughput Screening for the Discovery of Iron Homeostasis Modulators Using an Extremely Sensitive Fluorescent Probe
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Mechanisms of Mammalian Iron Homeostasis
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Iron Regulatory Element and Internal Loop/Bulge Structure for Ferritin mRNA Studied by Cobalt(III) Hexammine Binding, Molecular Modeling, and NMR Spectroscopy
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Detoxification of Cytotoxic Alachlor by Glutathione: Characterization of Conjugated Adducts by Electrospray Ionization Tandem Mass Spectrometry
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Transferrin receptor is necessary for development of erythrocytes and the nervous system
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Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
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The role of iron and reactive oxygen species in cell death
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Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice
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The resurgence of platinum-based cancer chemotherapy
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Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2
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Involvement of cigarette smoke-induced epithelial cell ferroptosis in COPD pathogenesis
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Multiscale interactome analysis coupled with off-target drug predictions reveals drug repurposing candidates for human coronavirus disease
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Hepcidin sequesters iron to sustain nucleotide metabolism and mitochondrial function in colorectal cancer epithelial cells
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Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
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Iron-sensitive fluorescent probes: monitoring intracellular iron pools
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The human iron-proteome†
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Regulation of cellular iron metabolism
inferredcites →https://doi.org/10.1073/pnas.0509744102openalex-snapshot
The up-regulation of ferritin expression using a small-molecule ligand to the native mRNA
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Direct Fe2+ Sensing by Iron-responsive Messenger RNA·Repressor Complexes Weakens Binding
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Review: Ferruginous Bodies: Implications in the Mechanism of Fiber and Particle Toxicity
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Intracellular Iron Transport and Storage: From Molecular Mechanisms to Health Implications
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Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene
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Cancer Incidence among Pesticide Applicators Exposed to Alachlor in the Agricultural Health Study
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Alachlor Use and Cancer Incidence in the Agricultural Health Study: An Updated Analysis
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TAK1 Inhibition Elicits Mitochondrial ROS to Block Intracellular Bacterial Colonization
inferredcites →https://doi.org/10.1111/bjh.13381openalex-snapshot
The iron chelator deferasirox affects redox signalling in haematopoietic stem/progenitor cells
inferredcites →https://doi.org/10.1111/cas.13234openalex-snapshot
BRAF mutations are associated with increased iron regulatory protein‐2 expression in colorectal tumorigenesis
inferredcites →https://doi.org/10.1126/sciadv.abg4302openalex-snapshot
Iron-sulfur cluster deficiency can be sensed by IRP2 and regulates iron homeostasis and sensitivity to ferroptosis independent of IRP1 and FBXL5
inferredcites →https://doi.org/10.1126/science.1176326openalex-snapshot
An E3 Ligase Possessing an Iron-Responsive Hemerythrin Domain Is a Regulator of Iron Homeostasis
inferredcites →https://doi.org/10.1126/science.1176333openalex-snapshot
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
inferredcites →https://doi.org/10.1128/mcb.00004-09openalex-snapshot
Cysteine Oxidation Regulates the RNA-Binding Activity of Iron Regulatory Protein 2
inferredcites →https://doi.org/10.1146/annurev.nutr.26.061505.111303openalex-snapshot
Regulation of Iron Metabolism by Hepcidin
inferredcites →https://doi.org/10.1155/2013/726954openalex-snapshot
Metal Dyshomeostasis and Inflammation in Alzheimer’s and Parkinson’s Diseases: Possible Impact of Environmental Exposures
inferredcites →https://doi.org/10.1158/0008-5472.can-13-1224openalex-snapshot
IRP2 Regulates Breast Tumor Growth
inferredcites →https://doi.org/10.1158/0008-5472.can-20-2017openalex-snapshot
Iron and Cancer: 2020 Vision
inferredcites →https://doi.org/10.1165/rcmb.2012-0011ocopenalex-snapshot
CHRNA3 / 5 , IREB2 , and ADCY2 Are Associated with Severe Chronic Obstructive Pulmonary Disease in Poland
inferredcites →https://doi.org/10.1165/rcmb.2014-0210ocopenalex-snapshot
IREB2 and GALC Are Associated with Pulmonary Artery Enlargement in Chronic Obstructive Pulmonary Disease
inferredcites →https://doi.org/10.1177/096032719601500902openalex-snapshot
Evaluation of the potential carcinogenicity and genetic toxicity to humans of the herbicide acetochlor
inferredcites →https://doi.org/10.1183/13993003.00711-2016openalex-snapshot
IRP2 as a potential modulator of cell proliferation, apoptosis and prognosis in nonsmall cell lung cancer
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Deferasirox drives ROS-mediated differentiation and induces interferon-stimulated gene expression in human healthy haematopoietic stem/progenitor cells and in leukemia cells
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Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3′-IRE stem–loops
inferredcites →https://doi.org/10.1371/journal.pone.0010163openalex-snapshot
Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert
inferredcites →https://doi.org/10.1371/journal.pone.0024395openalex-snapshot
Genetics of Sputum Gene Expression in Chronic Obstructive Pulmonary Disease
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Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice
inferredcites →https://doi.org/10.1371/journal.pone.0066220openalex-snapshot
Identification of Cisplatin-Binding Proteins Using Agarose Conjugates of Platinum Compounds
inferredcites →https://doi.org/10.1371/journal.pone.0098072openalex-snapshot
Abnormal Brain Iron Metabolism in Irp2 Deficient Mice Is Associated with Mild Neurological and Behavioral Impairments
inferredcites →https://doi.org/10.1371/journal.pone.0235563openalex-snapshot
Transmembrane protein western blotting: Impact of sample preparation on detection of SLC11A2 (DMT1) and SLC40A1 (ferroportin)
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The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity
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Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth
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Different Associations Between the IREB2 Variants and Chronic Obstructive Pulmonary Disease Susceptibility
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Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases
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Labile iron in cells and body fluids: physiology, pathology, and pharmacology
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Conservation in the Iron Responsive Element Family
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Targeting the Iron-Response Elements of the mRNAs for the Alzheimer’s Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity
inferredcites →https://doi.org/10.3390/ijms24043604openalex-snapshot
Optimization of Biotinylated RNA or DNA Pull-Down Assays for Detection of Binding Proteins: Examples of IRP1, IRP2, HuR, AUF1, and Nrf2
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Current Synthetic Routes to Peptidyl Mono-Fluoromethyl Ketones (FMKs) and Their Applications
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Article Commentary: Effects of Environmental Pollutants on Cellular Iron Homeostasis and Ultimate Links to Human Disease
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The Role of Iron Metabolism in Lung Inflammation and Injury
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