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Dtx3 Suppresses Bladder Cancer Cell Invasion and Metastasis by Inhibiting the Notch Signaling Pathway

https://doi.org/10.2139/ssrn.4996792
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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1001/jama.2020.17598openalex-snapshot
Bladder Cancer
inferredcites →https://doi.org/10.1007/s10549-021-06138-2openalex-snapshot
DTX3 copy number increase in breast cancer: a study of associations to molecular subtype, proliferation and prognosis
inferredcites →https://doi.org/10.1007/s11033-021-06916-7openalex-snapshot
Deltex E3 ubiquitin ligase 3 inhibits colorectal cancer cell growth and regulates cell cycle progression via upregulating E2F transcription factor 1
inferredcites →https://doi.org/10.1016/j.canlet.2019.07.012openalex-snapshot
Notch signaling in breast cancer: From pathway analysis to therapy
inferredcites →https://doi.org/10.1016/j.ccr.2014.02.018openalex-snapshot
From Fly Wings to Targeted Cancer Therapies: A Centennial for Notch Signaling
inferredcites →https://doi.org/10.1016/j.ceb.2023.102244openalex-snapshot
Mechanical regulation of the Notch signaling pathway
inferredcites →https://doi.org/10.1016/j.eururo.2023.03.029openalex-snapshot
Epidemiology of Bladder Cancer in 2023: A Systematic Review of Risk Factors
inferredcites →https://doi.org/10.1016/j.semcancer.2021.04.008openalex-snapshot
Notch signaling in cancer: Complexity and challenges on the path to clinical translation
inferredcites →https://doi.org/10.1016/j.str.2005.07.015openalex-snapshot
Structure and Notch Receptor Binding of the Tandem WWE Domain of Deltex
inferredcites →https://doi.org/10.1016/s0140-6736(22)01188-6openalex-snapshot
Current best practice for bladder cancer: a narrative review of diagnostics and treatments
inferredcites →https://doi.org/10.1038/ncb1327openalex-snapshot
Regulation of Notch signalling by non-visual β-arrestin
inferredcites →https://doi.org/10.1038/ng0598-74openalex-snapshot
Human deltex is a conserved regulator of Notch signalling
inferredcites →https://doi.org/10.1038/nm.3678openalex-snapshot
A new tumor suppressor role for the Notch pathway in bladder cancer
inferredcites →https://doi.org/10.1038/nrc3035openalex-snapshot
Notch signalling in solid tumours: a little bit of everything but not all the time
inferredcites →https://doi.org/10.1038/nrc3817openalex-snapshot
Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity
inferredcites →https://doi.org/10.1038/nrd4252openalex-snapshot
Therapeutic modulation of Notch signalling — are we there yet?
inferredcites →https://doi.org/10.1038/nrg3272openalex-snapshot
The Notch signalling system: recent insights into the complexity of a conserved pathway
inferredcites →https://doi.org/10.1038/nrm.2016.94openalex-snapshot
Notch signalling in context
inferredcites →https://doi.org/10.1038/s41585-018-0005-1openalex-snapshot
Unravelling disparate roles of NOTCH in bladder cancer
inferredcites →https://doi.org/10.1074/jbc.m105245200openalex-snapshot
Role of Deltex-1 as a Transcriptional Regulator Downstream of the Notch Receptor
inferredcites →https://doi.org/10.1074/jbc.m110.194936openalex-snapshot
Fbxw7-dependent Degradation of Notch Is Required for Control of “Stemness” and Neuronal-Glial Differentiation in Neural Stem Cells
inferredcites →https://doi.org/10.1074/jbc.m301157200openalex-snapshot
The BAL-binding Protein BBAP and Related Deltex Family Members Exhibit Ubiquitin-Protein Isopeptide Ligase Activity
inferredcites →https://doi.org/10.1080/15384101.2020.1859196openalex-snapshot
DCAF13 promotes triple-negative breast cancer metastasis by mediating DTX3 mRNA degradation
inferredcites →https://doi.org/10.1093/genetics/131.1.99openalex-snapshot
A genetic analysis of deltex and its interaction with the Notch locus in Drosophila melanogaster.
inferredcites →https://doi.org/10.1093/genetics/136.2.585openalex-snapshot
A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein.
inferredcites →https://doi.org/10.1111/cas.14288openalex-snapshot
Ubiquitination of NOTCH2 by DTX3 suppresses the proliferation and migration of human esophageal carcinoma
inferredcites →https://doi.org/10.1111/febs.15792openalex-snapshot
Regulation of Notch signaling by E3 ubiquitin ligases
inferredcites →https://doi.org/10.1111/jcmm.16674openalex-snapshot
Ring finger protein 19A is overexpressed in non‐small cell lung cancer and mediates p53 ubiquitin‐degradation to promote cancer growth
inferredcites →https://doi.org/10.1158/1078-0432.ccr-15-2360openalex-snapshot
Not all NOTCH Is Created Equal: The Oncogenic Role of NOTCH2 in Bladder Cancer and Its Implications for Targeted Therapy
inferredcites →https://doi.org/10.1172/jci120401openalex-snapshot
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis
inferredcites →https://doi.org/10.1172/jci152424openalex-snapshot
Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis
inferredcites →https://doi.org/10.1172/jci78185openalex-snapshot
NOTCH pathway inactivation promotes bladder cancer progression
inferredcites →https://doi.org/10.1186/1471-2407-14-628openalex-snapshot
Canonical Notch signalling is inactive in urothelial carcinoma
inferredcites →https://doi.org/10.1242/dev.063610openalex-snapshot
Notch signaling: simplicity in design, versatility in function
inferredcites →https://doi.org/10.1242/dev.121.8.2633openalex-snapshot
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats
inferredcites →https://doi.org/10.3322/caac.21834openalex-snapshot
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
inferredcites →https://doi.org/10.3389/fgene.2021.654736openalex-snapshot
Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma
inferredcites →https://doi.org/10.3390/cells12131680openalex-snapshot
The DTX Protein Family: An Emerging Set of E3 Ubiquitin Ligases in Cancer
inferredcites →https://doi.org/10.7150/jca.48141openalex-snapshot
Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway
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