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Global Hotspots and Development Trends in the New Generation of Artificial Heart Valves: A Bibliometric Analysis from 1991 to 2024

https://doi.org/10.2139/ssrn.5077607
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Polyurethane heart valves: Fatigue failure, calcification, and polyurethane structure
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Spatially Heterogeneous Tubular Scaffolds for In Situ Heart Valve Tissue Engineering Using Melt Electrowriting
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Programmable Melt Electrowriting to Engineer Soft Connective Tissues with Prescribed, Biomimetic, Biaxial Mechanical Properties
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Formulation and Evaluation of PVA/Gelatin/Carrageenan Inks for 3D Printing and Development of Tissue‐Engineered Heart Valves
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Developing a Clinically Relevant Tissue Engineered Heart Valve—A Review of Current Approaches
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Engineering Heart Valve Interfaces Using Melt Electrowriting: Biomimetic Design Strategies from Multi‐Modal Imaging
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Functional Oxidized Hyaluronic Acid Cross‐Linked Decellularized Heart Valves for Improved Immunomodulation, Anti‐Calcification, and Recellularization
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Development of Innovative Biomaterials and Devices for the Treatment of Cardiovascular Diseases
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Introducing Controlled Microporosity in Melt Electrowriting
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CiteSpace II: Detecting and visualizing emerging trends and transient patterns in scientific literature
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Science mapping software tools: Review, analysis, and cooperative study among tools
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Research on fatigue optimization simulation of polymeric heart valve based on the iterative sub‐regional thickened method
inferredcites →https://doi.org/10.1002/jbm.a.34420openalex-snapshot
3D Bioprinting of heterogeneous aortic valve conduits with alginate/gelatin hydrogels
inferredcites →https://doi.org/10.1002/jbm.a.37641openalex-snapshot
Hydrogel‐polyurethane fiber composites with enhanced microarchitectural control for heart valve replacement
inferredcites →https://doi.org/10.1002/jbm.b.30546openalex-snapshot
A novel polymer for potential use in a trileaflet heart valve
inferredcites →https://doi.org/10.1002/jbm.b.34427openalex-snapshot
Trilayer scaffold with cardiosphere‐derived cells for heart valve tissue engineering
inferredcites →https://doi.org/10.1002/jbm.b.35355openalex-snapshot
Bacterial cellulose as a promising material for pulmonary valve prostheses: In vivo study in a sheep model
inferredcites →https://doi.org/10.1002/mabi.201800390openalex-snapshot
Hybrid Pericardium with VEGF‐Loaded Hyaluronic Acid Hydrogel Coating to Improve the Biological Properties of Bioprosthetic Heart Valves
inferredcites →https://doi.org/10.1002/ped4.12359openalex-snapshot
Transcatheter pulmonary valve replacement in congenital heart diseases
inferredcites →https://doi.org/10.1002/smll.201900873openalex-snapshot
Biologically Inspired Scaffolds for Heart Valve Tissue Engineering via Melt Electrowriting
inferredcites →https://doi.org/10.1002/term.2010openalex-snapshot
Cells for tissue engineering of cardiac valves
inferredcites →https://doi.org/10.1007/s00276-009-0525-8openalex-snapshot
Diameters of normal thoracic vascular structures in pediatric patients
inferredcites →https://doi.org/10.1007/s00289-018-2450-7openalex-snapshot
A novel anti-calcification method for bioprosthetic heart valves using dopamine-modified alginate
inferredcites →https://doi.org/10.1007/s10439-016-1605-7openalex-snapshot
Implantation of a Tissue-Engineered Tubular Heart Valve in Growing Lambs
inferredcites →https://doi.org/10.1007/s10439-018-02119-7openalex-snapshot
Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Applications: In Vitro Hemodynamic Study
inferredcites →https://doi.org/10.1007/s10439-020-02466-4openalex-snapshot
Fluid–Structure Interaction Models of Bioprosthetic Heart Valve Dynamics in an Experimental Pulse Duplicator
inferredcites →https://doi.org/10.1007/s10439-022-03039-3openalex-snapshot
Designing a Novel Asymmetric Transcatheter Aortic Valve for Stenotic Bicuspid Aortic Valves Using Patient-Specific Computational Modeling
inferredcites →https://doi.org/10.1007/s10856-019-6237-7openalex-snapshot
Exogenous hyaluronic acid and chondroitin sulfate crosslinking treatment for increasing the amount and stability of glycosaminoglycans in bioprosthetic heart valves
inferredcites →https://doi.org/10.1007/s12265-016-9722-0openalex-snapshot
In Vitro Hydrodynamic Assessment of a New Transcatheter Heart Valve Concept (the TRISKELE)
inferredcites →https://doi.org/10.1007/s13239-016-0277-7openalex-snapshot
Morphology, Clinicopathologic Correlations, and Mechanisms in Heart Valve Health and Disease
inferredcites →https://doi.org/10.1007/s13239-020-00460-4openalex-snapshot
Transcatheter Mitral Valve Replacement: State of the Art
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Nonbacterial thrombotic endocarditis: A review
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Calcification and fatigue failure in a polyurethane heart valve
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Degradation of Biomaterials
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Tissue-engineered heart valves
inferredcites →https://doi.org/10.1016/b978-0-12-814661-3.00007-1openalex-snapshot
Computer modeling and simulation of heart valve function and intervention
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In vitro experimental methods for assessment of prosthetic heart valves
inferredcites →https://doi.org/10.1016/b978-0-12-814661-3.00013-7openalex-snapshot
Polymeric heart valves
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A novel nanocomposite polymer for development of synthetic heart valve leaflets
inferredcites →https://doi.org/10.1016/j.actbio.2012.01.006openalex-snapshot
Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture
inferredcites →https://doi.org/10.1016/j.actbio.2013.12.005openalex-snapshot
Three-dimensional printed trileaflet valve conduits using biological hydrogels and human valve interstitial cells
inferredcites →https://doi.org/10.1016/j.actbio.2019.02.002openalex-snapshot
Modifying decellularized aortic valve scaffolds with stromal cell-derived factor-1α loaded proteolytically degradable hydrogel for recellularization and remodeling
inferredcites →https://doi.org/10.1016/j.actbio.2021.04.046openalex-snapshot
Collagen fibre-mediated mechanical damage increases calcification of bovine pericardium for use in bioprosthetic heart valves
inferredcites →https://doi.org/10.1016/j.actbio.2024.10.045openalex-snapshot
Polymeric artificial heart valves derived from modified diol-based polycarbonate polyurethanes
inferredcites →https://doi.org/10.1016/j.addr.2011.01.008openalex-snapshot
Aortic valve disease and treatment: The need for naturally engineered solutions
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Valvular Heart Disease: Classic Teaching and Emerging Paradigms
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Reoperation After the Ross Procedure: Incidence, Management, and Survival
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Structural and temporal dynamics analysis on drug-eluting stents: History, research hotspots and emerging trends
inferredcites →https://doi.org/10.1016/j.bioactmat.2024.01.017openalex-snapshot
Structural and temporal dynamics analysis of zinc-based biomaterials: History, research hotspots and emerging trends
inferredcites →https://doi.org/10.1016/j.biomaterials.2008.01.001openalex-snapshot
The effect of bioactive hydrogels on the secretion of extracellular matrix molecules by valvular interstitial cells
inferredcites →https://doi.org/10.1016/j.biomaterials.2009.10.019openalex-snapshot
The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells
inferredcites →https://doi.org/10.1016/j.biomaterials.2011.05.078openalex-snapshot
Immune responses to implants – A review of the implications for the design of immunomodulatory biomaterials
inferredcites →https://doi.org/10.1016/j.biomaterials.2012.03.015openalex-snapshot
Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno- and homografts
inferredcites →https://doi.org/10.1016/j.biomaterials.2013.04.059openalex-snapshot
Off-the-shelf human decellularized tissue-engineered heart valves in a non-human primate model
inferredcites →https://doi.org/10.1016/j.biomaterials.2013.12.072openalex-snapshot
Engineering hybrid polymer-protein super-aligned nanofibers via rotary jet spinning
inferredcites →https://doi.org/10.1016/j.biomaterials.2014.09.013openalex-snapshot
Polymeric heart valves for surgical implantation, catheter-based technologies and heart assist devices
inferredcites →https://doi.org/10.1016/j.biomaterials.2017.02.007openalex-snapshot
In situ heart valve tissue engineering using a bioresorbable elastomeric implant – From material design to 12 months follow-up in sheep
inferredcites →https://doi.org/10.1016/j.biomaterials.2017.04.033openalex-snapshot
JetValve: Rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement
inferredcites →https://doi.org/10.1016/j.biomaterials.2017.10.011openalex-snapshot
Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure
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Mechanical considerations for polymeric heart valve development: Biomechanics, materials, design and manufacturing
inferredcites →https://doi.org/10.1016/j.biomaterials.2022.121675openalex-snapshot
Strategies for development of decellularized heart valve scaffolds for tissue engineering
inferredcites →https://doi.org/10.1016/j.biopha.2021.111288openalex-snapshot
Structural stability of novel composite heart valve prostheses - Fatigue and wear performance
inferredcites →https://doi.org/10.1016/j.bios.2021.113932openalex-snapshot
Frontier and hot topics in electrochemiluminescence sensing technology based on CiteSpace bibliometric analysis
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Heart valve health, disease, replacement, and repair: a 25-year cardiovascular pathology perspective
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Material modeling and recent findings in transcatheter aortic valve implantation simulations
inferredcites →https://doi.org/10.1016/j.compbiomed.2022.105440openalex-snapshot
Design of an aortic polymeric valve with asymmetric leaflets and evaluation of its performance by finite element method
inferredcites →https://doi.org/10.1016/j.compbiomed.2023.107623openalex-snapshot
Mechanical modeling of the maturation process for tissue-engineered implants: Application to biohybrid heart valves
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Double bond crosslinked and phosphocholinated biological heart valve with robust antithrombogenicity, durability and anticalcification property
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Bioinspired NiTi-reinforced polymeric heart valve exhibiting excellent hemodynamics and reduced stress
inferredcites →https://doi.org/10.1016/j.eurpolymj.2024.113349openalex-snapshot
Siloxane-based segmented poly(urethane-urea) elastomers with enhanced mechanical properties, hydrophobicity and anti-calcification based on hierarchical phase separation for potential applications of polymeric heart valve
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Chitosan/hyaluronic acid polyanion bilayer applied from carbon acid as an advanced coating with intelligent antimicrobial properties for improved biological prosthetic heart valves
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Surgical pericardial heart valves: 50 Years of evolution
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In Situ Remodeling Overrules Bioinspired Scaffold Architecture of Supramolecular Elastomeric Tissue-Engineered Heart Valves
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Minimally-Invasive Implantation of Living Tissue Engineered Heart Valves
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Cost-Effectiveness of Transcatheter Aortic Valve Replacement Compared With Surgical Aortic Valve Replacement in High-Risk Patients With Severe Aortic Stenosis
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Transcatheter Implantation of Homologous “Off-the-Shelf” Tissue-Engineered Heart Valves With Self-Repair Capacity
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Challenges in Infective Endocarditis
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Preliminary Implantation of a Novel TAVR Device With Polymeric Leaflets for Symptomatic Calcific Aortic Disease
inferredcites →https://doi.org/10.1016/j.jmst.2018.09.026openalex-snapshot
Novel transcatheter aortic heart valves exhibiting excellent hemodynamic performance and low-fouling property
inferredcites →https://doi.org/10.1016/j.joi.2018.03.005openalex-snapshot
Examining the usage, citation, and diffusion patterns of bibliometric mapping software: A comparative study of three tools
inferredcites →https://doi.org/10.1016/j.jtcvs.2009.11.006openalex-snapshot
In vivo monitoring of function of autologous engineered pulmonary valve
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A novel restorative pulmonary valved conduit in a chronic sheep model: Mid-term hemodynamic function and histologic assessment
inferredcites →https://doi.org/10.1016/j.jtcvs.2019.09.164openalex-snapshot
Failure of decellularized porcine small intestinal submucosa as a heart valved conduit
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Bioinspired Heart Valve Prosthesis Made by Silicone Additive Manufacturing
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Fabricating hydrogels to mimic biological tissues of complex shapes and high fatigue resistance
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On-demand heart valve manufacturing using focused rotary jet spinning
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Biomaterials and biofabrication strategies for tissue-engineered heart valves
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T cell mimicry in inflammatory heart disease
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Materials and manufacturing perspectives in engineering heart valves: a review
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Recent advancements in polymeric heart valves: From basic research to clinical trials
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Transcatheter aortic valve replacement (TAVR): Recent updates
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An overview of scientometric mapping for the safety science community: Methods, tools, and framework
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A Perivascular Origin for Mesenchymal Stem Cells in Multiple Human Organs
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3D printing of heart valves
inferredcites →https://doi.org/10.1016/s0003-4975(03)01300-6openalex-snapshot
Preclinical assessment of a trileaflet mechanical valve in the mitral position in a calf model
inferredcites →https://doi.org/10.1016/s0021-9290(00)00003-8openalex-snapshot
A synthetic fiber-reinforced stentless heart valve
inferredcites →https://doi.org/10.1016/s0022-5223(00)70008-0openalex-snapshot
Tissue-engineered valved conduits in the pulmonary circulation
inferredcites →https://doi.org/10.1016/s0022-5223(19)41751-0openalex-snapshot
Scanning and light microscopy of human aortic leaflets in stressed and relaxed states
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Burden of valvular heart diseases: a population-based study
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A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease
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Early failure of the tissue engineered porcine heart valve SYNERGRAFT™ in pediatric patients
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Biomechanically Compatible Hydrogel Bioprosthetic Valves
inferredcites →https://doi.org/10.1021/acsabm.9b00911openalex-snapshot
Interfacial Coating Method for Amine-Rich Surfaces using Poly(ethylene glycol) Diacrylate Applied to Bioprosthetic Valve Tissue Models
inferredcites →https://doi.org/10.1021/acsami.5b07254openalex-snapshot
Physical Characterization and Platelet Interactions under Shear Flows of a Novel Thermoset Polyisobutylene-based Co-polymer
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Poly(2-methacryloyloxyethyl phosphorylcholine) Grafted Bioprosthetic Heart Valve Exhibited Improved Antithrombogenicity and Anticalcification Properties
inferredcites →https://doi.org/10.1021/acsbiomaterials.8b01311openalex-snapshot
Nonglutaraldehyde Fixation for off the Shelf Decellularized Bovine Pericardium in Anticalcification Cardiac Valve Applications
inferredcites →https://doi.org/10.1021/bm050590zopenalex-snapshot
The Antithrombogenic Potential of a Polyhedral Oligomeric Silsesquioxane (POSS) Nanocomposite
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Will heart valve tissue engineering change the world?
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Current perspectives on treatment of valvular heart disease
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Facile engineering of interactive double network hydrogels for heart valve regeneration
inferredcites →https://doi.org/10.1038/s41569-020-0422-8openalex-snapshot
Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity
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Fabrication and In Vitro Characterization of a Tissue Engineered PCL-PLLA Heart Valve
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A New Nanocomposite Copolymer Based On Functionalised Graphene Oxide for Development of Heart Valves
inferredcites →https://doi.org/10.1038/s41598-020-76322-9openalex-snapshot
Geometry influences inflammatory host cell response and remodeling in tissue-engineered heart valves in-vivo
inferredcites →https://doi.org/10.1039/c8tb02565gopenalex-snapshot
Hydrogel hybrid porcine pericardium for the fabrication of a pre-mounted TAVI valve with improved biocompatibility
inferredcites →https://doi.org/10.1039/c9tb00879aopenalex-snapshot
Pre-mounted dry TAVI valve with improved endothelialization potential using REDV-loaded PEGMA hydrogel hybrid pericardium
inferredcites →https://doi.org/10.1039/d0bm00412jopenalex-snapshot
Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis
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Performance characterization and biocompatibility assessment of silicone polyurethanes for polymer heart valve applications
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Calcific Aortic Stenosis — Time to Look More Closely at the Valve
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Global, Regional, and National Burden of Rheumatic Heart Disease, 1990–2015
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Bioprosthetic heart valve structural degeneration associated with metabolic syndrome: Mitigation with polyoxazoline modification
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Bovine pericardium leaflet damage during transcatheter aortic valve crimping: a study of the mechanisms
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A review of polymeric heart valves leaflet geometric configuration and structural optimization
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Rotary jet spinning review – a potential high yield future for polymer nanofibers
inferredcites →https://doi.org/10.1088/1748-605x/ab3d24openalex-snapshot
Optimization of polycaprolactone fibrous scaffold for heart valve tissue engineering
inferredcites →https://doi.org/10.1088/1748-605x/ab52e2openalex-snapshot
Trilayered tissue structure with leaflet-like orientations developed through in vivo tissue engineering
inferredcites →https://doi.org/10.1088/1748-605x/ab6f46openalex-snapshot
Curcumin-crosslinked acellular bovine pericardium for the application of calcification inhibition heart valves
inferredcites →https://doi.org/10.1088/1748-605x/aba239openalex-snapshot
Tough pNAGA hydrogel hybridized porcine pericardium for the pre-mounted TAVI valve with improved anti-tearing properties and hemocompatibility
inferredcites →https://doi.org/10.1088/1748-605x/ac94aeopenalex-snapshot
Anisotropicity and flexibility in trilayered microfibrous substrates promote heart valve leaflet tissue engineering
inferredcites →https://doi.org/10.1088/1748-605x/ac9f91openalex-snapshot
3D-bioprinting of aortic valve interstitial cells: impact of hydrogel and printing parameters on cell viability
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Analysis of bioprinting strategies for skin diseases and injuries through structural and temporal dynamics: historical perspectives, research hotspots, and emerging trends
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Allograft Heart Valves: Current Aspects and Future Applications
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Endothelial Progenitor Cells as a Sole Source for Ex Vivo Seeding of Tissue-Engineered Heart Valves
inferredcites →https://doi.org/10.1093/rb/rbad098openalex-snapshot
Recent progress in functional modification and crosslinking of bioprosthetic heart valves
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Application of Stereolithography for Scaffold Fabrication for Tissue Engineered Heart Valves
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Challenges in tissue engineering
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A review of the immune response stimulated by xenogenic tissue heart valves
inferredcites →https://doi.org/10.1111/xen.12080openalex-snapshot
Bioprosthetic heart valves of the future
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Visions of TAVR Future: Development and Optimization of a Second Generation Novel Polymeric TAVR
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3D printed patient-specific aortic root models with internal sensors for minimally invasive applications
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Computational modeling guides tissue-engineered heart valve design for long-term in vivo performance in a translational sheep model
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Pediatric tri-tube valved conduits made from fibroblast-produced extracellular matrix evaluated over 52 weeks in growing lambs
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Bioengineering Challenges for Heart Valve Tissue Engineering
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Heart Valve Structure and Function in Development and Disease
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Aortic Valve Disease
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Tissue Engineering of Functional Trileaflet Heart Valves From Human Marrow Stromal Cells
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Functional Living Trileaflet Heart Valves Grown In Vitro
inferredcites →https://doi.org/10.1161/01.cir.103.11.1522openalex-snapshot
Bone Formation and Inflammation in Cardiac Valves
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Distribution of circumferential stress in ruptured and stable atherosclerotic lesions. A structural analysis with histopathological correlation.
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Challenges and Opportunities in Valvular Heart Disease: From Molecular Mechanisms to the Community
inferredcites →https://doi.org/10.1161/circ.102.suppl_3.iii-44openalex-snapshot
Functional Living Trileaflet Heart Valves Grown In Vitro
inferredcites →https://doi.org/10.1161/circresaha.111.256149openalex-snapshot
Steps Toward Safe Cell Therapy Using Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1161/circulationaha.104.498378openalex-snapshot
From Stem Cells to Viable Autologous Semilunar Heart Valve
inferredcites →https://doi.org/10.1161/circulationaha.105.591768openalex-snapshot
Human Semilunar Cardiac Valve Remodeling by Activated Cells From Fetus to Adult
inferredcites →https://doi.org/10.1161/circulationaha.106.183095openalex-snapshot
Prevention of Infective Endocarditis
inferredcites →https://doi.org/10.1177/0885328214530589openalex-snapshot
Fiber-reinforced hydrogel scaffolds for heart valve tissue engineering
inferredcites →https://doi.org/10.1186/s12872-019-01312-3openalex-snapshot
Advances in transcatheter mitral and tricuspid therapies
inferredcites →https://doi.org/10.1186/s13019-020-01292-yopenalex-snapshot
Clinical performance of decellularized heart valves versus standard tissue conduits: a systematic review and meta-analysis
inferredcites →https://doi.org/10.1371/journal.pone.0039969openalex-snapshot
Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus
inferredcites →https://doi.org/10.1515/jdis-2017-0006openalex-snapshot
Science Mapping: A Systematic Review of the Literature
inferredcites →https://doi.org/10.1517/14712598.2015.1051527openalex-snapshot
Current progress in tissue engineering of heart valves: multiscale problems, multiscale solutions
inferredcites →https://doi.org/10.1586/erd.09.12openalex-snapshot
Tissue engineering of heart valves: advances and current challenges
inferredcites →https://doi.org/10.1615/jlongtermeffmedimplants.2015011817openalex-snapshot
Application of Hydrogels in Heart Valve Tissue Engineering
inferredcites →https://doi.org/10.3145/epi.2020.ene.03openalex-snapshot
Software tools for conducting bibliometric analysis in science: An up-to-date review
inferredcites →https://doi.org/10.3389/fbioe.2022.844010openalex-snapshot
Improved Cytocompatibility and Reduced Calcification of Glutaraldehyde-Crosslinked Bovine Pericardium by Modification With Glutathione
inferredcites →https://doi.org/10.3389/fbioe.2022.988533openalex-snapshot
Biohybrid elastin-like venous valve with potential for in situ tissue engineering
inferredcites →https://doi.org/10.3389/fcvm.2018.00155openalex-snapshot
Cell Sources for Tissue Engineering Strategies to Treat Calcific Valve Disease
inferredcites →https://doi.org/10.3389/fcvm.2022.791949openalex-snapshot
The Technological Basis of a Balloon-Expandable TAVR System: Non-occlusive Deployment, Anchorage in the Absence of Calcification and Polymer Leaflets
inferredcites →https://doi.org/10.3389/fcvm.2023.1137827openalex-snapshot
Polymeric prosthetic heart valves: A review of current technologies and future directions
inferredcites →https://doi.org/10.3390/ijms23158567openalex-snapshot
Biofabrication of Sodium Alginate Hydrogel Scaffolds for Heart Valve Tissue Engineering
inferredcites →https://doi.org/10.3390/ijms24043963openalex-snapshot
Polymeric Heart Valves Will Displace Mechanical and Tissue Heart Valves: A New Era for the Medical Devices
inferredcites →https://doi.org/10.3390/jcdd7040057openalex-snapshot
Biology and Biomechanics of the Heart Valve Extracellular Matrix
inferredcites →https://doi.org/10.3390/medicina58111695openalex-snapshot
Engineering a New Polymeric Heart Valve Using 3D Printing—TRISKELION
inferredcites →https://doi.org/10.3390/medsci10020032openalex-snapshot
Valvular Heart Disease Epidemiology
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