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Α-Bromoketone Derivatives from Lithocholic Acid: A Comprehensive Evaluation of Their Antibacterial Activity

https://doi.org/10.2139/ssrn.5120336
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Darstellung der Ester
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p-Hydroxybenzoic Acid Esters as Preservatives*
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Transport across the bacterial outer membrane
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The biosynthesis of ethyl lithocholate by fecal microorganisms
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
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Outer membrane permeability and antibiotic resistance
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New lithocholic and chenodeoxycholic piperazinylcarboxamides with antiproliferative and pro-apoptotic effects on human cancer cell lines
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Lithocholic acid and derivatives: Antibacterial activity
inferredcites →https://doi.org/10.1016/j.steroids.2025.109560openalex-snapshot
Improved synthesis and characterization of bile acid esters: Organogelation and supramolecular properties
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PREPARATION OF DEUTERIUM STEROID HORMONES FROM BILE ACIDS AND THE FORMATION OF α,β-UNSATURATED KETONES FROM 3-KETOCHOLANE DERIVATIVES
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Nuclear magnetic resonance spectroscopy of bile acids. Development of two-dimensional NMR methods for the elucidation of proton resonance assignments for five common hydroxylated bile acids, and their parent bile acid, 5 beta-cholanoic acid.
inferredcites →https://doi.org/10.1016/s0076-6879(77)46014-2openalex-snapshot
[10] Haloketones as affinity labeling reagents
inferredcites →https://doi.org/10.1016/s0169-409x(96)00423-1openalex-snapshot
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
inferredcites →https://doi.org/10.1016/s0378-4347(00)83187-4openalex-snapshot
Separation and quantitation of fatty acids, sterols and bile acids in feces by gas chromatography as the butyl ester—acetate derivatives
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Replacement of Less-Preferred Dipolar Aprotic and Ethereal Solvents in Synthetic Organic Chemistry with More Sustainable Alternatives
inferredcites →https://doi.org/10.1021/acs.jnatprod.8b00382openalex-snapshot
Helvolic Acid Derivatives with Antibacterial Activities against Streptococcus agalactiae from the Marine-Derived Fungus Aspergillus fumigatus HNMF0047
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Oxidations and Dehydrogenations with N-Bromosuccinimide and Related N-Haloimides.
inferredcites →https://doi.org/10.1021/ja01114a011openalex-snapshot
Preparation and Dehydrohalogenation of 4-Halo-3-ketosteroids
inferredcites →https://doi.org/10.1021/ja01135a039openalex-snapshot
Simultaneous Oxidation and Bromination of 21-Acetoxypregnan-3α,17α-diol-11,20-dione
inferredcites →https://doi.org/10.1021/ja01171a066openalex-snapshot
The Scope and Mechanism of the Reaction of Dinitrophenylhydrazine with Steroidal Bromo Ketones
inferredcites →https://doi.org/10.1021/ja01630a046openalex-snapshot
The Stereochemistry of α-Haloketones. V. Prediction of the Stereochemistry of α-Brominated Ketosteroids
inferredcites →https://doi.org/10.1021/ja01641a020openalex-snapshot
Chemical Studies with 11-Oxygenated Steroids. V. A One-Step Oxidation-Halogenation of 3-Hydroxysteroids
inferredcites →https://doi.org/10.1021/jo01348a015openalex-snapshot
Some Reactions of Steroidal α-Bromo Ketones1
inferredcites →https://doi.org/10.1023/a:1018907026460openalex-snapshot
Soft Drugs Based on Hydrocortisone: The Inactive Metabolite Approach and Its Application to Steroidal Antiinflammatory Agents
inferredcites →https://doi.org/10.1038/s41598-024-57251-3openalex-snapshot
Bile acid metabolites enhance expression of cathelicidin antimicrobial peptide in airway epithelium through activation of the TGR5-ERK1/2 pathway
inferredcites →https://doi.org/10.1038/srep42717openalex-snapshot
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
inferredcites →https://doi.org/10.1039/c5nj01718aopenalex-snapshot
The role of atropisomers on the photo-reactivity and fatigue of diarylethene-based metal–organic frameworks
inferredcites →https://doi.org/10.1039/d3ra08086bopenalex-snapshot
Lithocholic acid derivatives as potent modulators of the nuclear receptor RORγt
inferredcites →https://doi.org/10.1039/p29900001567openalex-snapshot
A survey of the high-field 1H NMR spectra of the steroid hormones, their hydroxylated derivatives, and related compounds
inferredcites →https://doi.org/10.1055/s-0035-1562519openalex-snapshot
Solid-Phase Synthesis of Heterocycles with α-Haloketones as the Key Building Blocks
inferredcites →https://doi.org/10.1080/00397918608078765openalex-snapshot
Synthetic Studies on Vitamin D Analogues VI. A New Synthesis of 25-Hydroxycholesterol from Lithocholic Acid
inferredcites →https://doi.org/10.1111/jam.14921openalex-snapshot
Characterization of a non‐glycosylated fraction from honey proteins of Melipona beecheii with antimicrobial activity against Escherichia coli O157:H7
inferredcites →https://doi.org/10.1128/9781683670131.ch1openalex-snapshot
The Gram-Positive Bacterial Cell Wall
inferredcites →https://doi.org/10.1201/9781420014495.ch3openalex-snapshot
Disk Diffusion Test and Gradient Methodologies
inferredcites →https://doi.org/10.1201/9781420014495.ch4openalex-snapshot
Macro- and Microdilution Methods of Antimicrobial Susceptibility Testing
inferredcites →https://doi.org/10.1248/cpb.27.252openalex-snapshot
The convenient synthesis of 25-hydroxycholesterol.
inferredcites →https://doi.org/10.1517/17460441.2012.714363openalex-snapshot
The influence of lipophilicity in drug discovery and design
inferredcites →https://doi.org/10.2139/ssrn.4997404openalex-snapshot
Improved Synthesis and Characterization of Bile Acid Esters: Organogelation and Supramolecular Properties
inferredcites →https://doi.org/10.3390/81100793openalex-snapshot
The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis
inferredcites →https://doi.org/10.3390/biomedicines11102698openalex-snapshot
Steroids Bearing Heteroatom as Potential Drugs for Medicine
inferredcites →https://doi.org/10.3390/healthcare11131946openalex-snapshot
Antimicrobial Resistance: A Growing Serious Threat for Global Public Health
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