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Osthole Regulates the Bile Acid-Gut Microbiota Axis Via Fxr to Ameliorate Dss-Induced Ulcerative Colitis

https://doi.org/10.2139/ssrn.5256346
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ROS-modulated therapeutic approaches in cancer treatment
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Osthole ameliorates neurogenic and inflammatory hyperalgesia by modulation of iNOS, COX-2, and inflammatory cytokines in mice
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IBD and the Gut Microbiota—from Bench to Personalized Medicine
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Pleiotropic Roles of Bile Acids in Metabolism
inferredcites →https://doi.org/10.1016/j.coph.2020.04.008openalex-snapshot
Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders
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Microgeographic Proteomic Networks of the Human Colonic Mucosa and Their Association With Inflammatory Bowel Disease
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Protective effects of scutellaria-coptis herb couple against non-alcoholic steatohepatitis via activating NRF2 and FXR pathways in vivo and in vitro
inferredcites →https://doi.org/10.1016/j.jhazmat.2024.134821openalex-snapshot
Butylparaben induces glycolipid metabolic disorders in mice via disruption of gut microbiota and FXR signaling
inferredcites →https://doi.org/10.1016/j.lfs.2022.121312openalex-snapshot
Deferasirox alleviates DSS-induced ulcerative colitis in mice by inhibiting ferroptosis and improving intestinal microbiota
inferredcites →https://doi.org/10.1016/j.phymed.2024.155466openalex-snapshot
Exploring the pathophysiological influence of heme oxygenase-1 on neuroinflammation and depression: A study of phytotherapeutic-based modulation
inferredcites →https://doi.org/10.1016/j.tibtech.2015.06.011openalex-snapshot
Proteobacteria: microbial signature of dysbiosis in gut microbiota
inferredcites →https://doi.org/10.1016/j.tiv.2016.11.014openalex-snapshot
Pharmacotoxicology of clinically-relevant concentrations of obeticholic acid in an organotypic human hepatocyte system
inferredcites →https://doi.org/10.1016/s0140-6736(13)60844-2openalex-snapshot
Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study
inferredcites →https://doi.org/10.1016/s1875-9572(08)60028-5openalex-snapshot
Effect of the Chinese Herb Extract Osthol on IL-4-induced Eotaxin Expression in BEAS-2B Cells
inferredcites →https://doi.org/10.1021/acs.jafc.0c06755openalex-snapshot
Troxerutin Improves Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice
inferredcites →https://doi.org/10.1038/aps.2017.71openalex-snapshot
Osthole pretreatment alleviates TNBS-induced colitis in mice via both cAMP/PKA-dependent and independent pathways
inferredcites →https://doi.org/10.1038/nrgastro.2017.119openalex-snapshot
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
inferredcites →https://doi.org/10.1038/s41575-019-0258-zopenalex-snapshot
Gut microbiota-derived metabolites as key actors in inflammatory bowel disease
inferredcites →https://doi.org/10.1074/jbc.m412752200openalex-snapshot
The Heteromeric Organic Solute Transporter α-β, Ostα-Ostβ, Is an Ileal Basolateral Bile Acid Transporter
inferredcites →https://doi.org/10.1080/19490976.2015.1127483openalex-snapshot
Consequences of bile salt biotransformations by intestinal bacteria
inferredcites →https://doi.org/10.1093/ecco-jcc/jjz002openalex-snapshot
Colonic Mucosal Transcriptomic Changes in Patients with Long-Duration Ulcerative Colitis Revealed Colitis-Associated Cancer Pathways
inferredcites →https://doi.org/10.1093/gastro/goae053openalex-snapshot
Global patterns in the epidemiology, cancer risk, and surgical implications of inflammatory bowel disease
inferredcites →https://doi.org/10.1097/fjc.0000000000001320openalex-snapshot
The Critical Effect of Bile Acids in Atherosclerosis
inferredcites →https://doi.org/10.1111/jcmm.16459openalex-snapshot
Osthole Enhances the Immunosuppressive Effects of Bone Marrow-Derived Mesenchymal Stem Cells by Promoting the Fas/FasL System
inferredcites →https://doi.org/10.1124/mol.107.039370openalex-snapshot
Activation of Nuclear Factor (Erythroid-2 Like) Factor 2 by Toxic Bile Acids Provokes Adaptive Defense Responses to Enhance Cell Survival at the Emergence of Oxidative Stress
inferredcites →https://doi.org/10.1136/gutjnl-2014-307649openalex-snapshot
Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii , a commensal bacterium deficient in Crohn’s disease
inferredcites →https://doi.org/10.1155/2018/4039019openalex-snapshot
Development of a Traditional Chinese Medicine Syndrome‐Specific Scale for Ulcerative Colitis: The Large Intestine Dampness‐Heat Syndrome Questionnaire
inferredcites →https://doi.org/10.1186/s12944-023-01971-4openalex-snapshot
Altered fecal bile acid composition in active ulcerative colitis
inferredcites →https://doi.org/10.1371/journal.pone.0050810openalex-snapshot
The Ileal Lipid Binding Protein Is Required for Efficient Absorption and Transport of Bile Acids in the Distal Portion of the Murine Small Intestine
inferredcites →https://doi.org/10.1371/journal.pone.0294169openalex-snapshot
Propolis alleviates ulcerative colitis injury by inhibiting the protein kinase C ‐ transient receptor potential cation channel subfamily V member 1 ‐ calcitonin gene-related peptide/substance P (PKC-TRPV1-CGRP/SP) signaling axis
inferredcites →https://doi.org/10.1515/znc-2009-5-610openalex-snapshot
Immunomodulatory and Anti-Inflammatory Activity of Selected Osthole Derivatives
inferredcites →https://doi.org/10.2147/ceg.s4343openalex-snapshot
Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis
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Hepatoprotective Effects of Cilnidipine in Cholestatic Liver Disease: Role of FXR and NRF2 Signalling
inferredcites →https://doi.org/10.3389/fphar.2024.1494210openalex-snapshot
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Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis
inferredcites →https://doi.org/10.4103/1735-5362.359432openalex-snapshot
Antioxidant and genoprotective effects of osthole against cadmium-induced DNA damage
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