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Hippocampal transcriptomic remodeling following heat stress implicates complement and coagulation pathways in neural stem cell-associated responses

https://doi.org/10.2139/ssrn.7513480
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Outgoing claims: the papers this work cites, builds on, or argues with.

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The Orphan Nuclear Receptor NR4A1 Specifies a Distinct Subpopulation of Quiescent Myeloid-Biased Long-Term HSCs
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The Classical Complement Cascade Mediates CNS Synapse Elimination
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Adult Neurogenesis in the Hippocampus: From Stem Cells to Behavior
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A Fatty Acid Oxidation-Dependent Metabolic Shift Regulates Adult Neural Stem Cell Activity
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Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT
inferredcites →https://doi.org/10.1016/j.heliyon.2024.e37319openalex-snapshot
Genetic patterning in hippocampus of rat undergoing impaired spatial memory induced by long-term heat stress
inferredcites →https://doi.org/10.1016/j.neuron.2016.12.017openalex-snapshot
Role of Mitochondrial Metabolism in the Control of Early Lineage Progression and Aging Phenotypes in Adult Hippocampal Neurogenesis
inferredcites →https://doi.org/10.1016/j.neuron.2017.10.008openalex-snapshot
Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage
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Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
inferredcites →https://doi.org/10.1021/pr501312topenalex-snapshot
Heat-Stress-Induced Metabolic Changes and Altered Male Reproductive Function
inferredcites →https://doi.org/10.1038/3305openalex-snapshot
Neurogenesis in the adult human hippocampus
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Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis
inferredcites →https://doi.org/10.1038/ncomms15096openalex-snapshot
Developmental activities of the complement pathway in migrating neurons
inferredcites →https://doi.org/10.1038/nm0603-669openalex-snapshot
The biology of VEGF and its receptors
inferredcites →https://doi.org/10.1038/s41467-020-14466-yopenalex-snapshot
Fibrinogen induces neural stem cell differentiation into astrocytes in the subventricular zone via BMP signaling
inferredcites →https://doi.org/10.1038/s41591-019-0375-9openalex-snapshot
Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease
inferredcites →https://doi.org/10.1038/s41591-024-03395-8openalex-snapshot
A systematic review and meta-analysis of heat exposure impacts on maternal, fetal and neonatal health
inferredcites →https://doi.org/10.1080/14728222.2017.1279146openalex-snapshot
The NR4A subfamily of nuclear receptors: potential new therapeutic targets for the treatment of inflammatory diseases
inferredcites →https://doi.org/10.1093/bioinformatics/bty560openalex-snapshot
fastp: an ultra-fast all-in-one FASTQ preprocessor
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The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
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Fatty acid transport proteins
inferredcites →https://doi.org/10.1097/wnr.0000000000002042openalex-snapshot
Heat stress induces IL-1β and IL-18 overproduction via ROS-activated NLRP3 inflammasome: implication in neuroinflammation in mice with heat stroke
inferredcites →https://doi.org/10.1109/tbme.2025.3537297openalex-snapshot
Thermal Threshold for Localized Blood-Brain Barrier Disruption
inferredcites →https://doi.org/10.1126/science.abl5163openalex-snapshot
Impact of neurodegenerative diseases on human adult hippocampal neurogenesis
inferredcites →https://doi.org/10.1152/ajpregu.00712.2005openalex-snapshot
Heat stress reduces cerebral blood velocity and markedly impairs orthostatic tolerance in humans
inferredcites →https://doi.org/10.1161/circulationaha.120.045765openalex-snapshot
Extracellular Vesicle–Mediated Delivery of Circular RNA SCMH1 Promotes Functional Recovery in Rodent and Nonhuman Primate Ischemic Stroke Models
inferredcites →https://doi.org/10.1378/chest.124.3_suppl.26sopenalex-snapshot
The Protein C Pathway
inferredcites →https://doi.org/10.1523/jneurosci.2723-06.2006openalex-snapshot
Tumor Necrosis Factor Receptor 1 Is a Negative Regulator of Progenitor Proliferation in Adult Hippocampal Neurogenesis
inferredcites →https://doi.org/10.1523/jneurosci.4491-12.2013openalex-snapshot
An Activated Protein C Analog Stimulates Neuronal Production by Human Neural Progenitor Cells via a PAR1-PAR3-S1PR 1 -Akt Pathway
inferredcites →https://doi.org/10.2174/092986708783955455openalex-snapshot
Fibrinolysis: The Key to New Pathogenetic Mechanisms
inferredcites →https://doi.org/10.3389/fnins.2024.1437216openalex-snapshot
How can heatstroke damage the brain? A mini review
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Role of neuroinflammation mediated potential alterations in adult neurogenesis as a factor for neuropsychiatric symptoms in Post-Acute COVID-19 syndrome—A narrative review
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