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Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Long-term Ocular Manifestations in Nephropathic Cystinosis
inferredcites →https://doi.org/10.1001/archopht.1987.01060120065025openalex-snapshot
Contrast Sensitivity Function in Nephropathic Cystinosis
inferredcites →https://doi.org/10.1001/archopht.1989.01070020809012openalex-snapshot
Crystal Deposition Following Keratoplasty in Nephropathic Cystinosis
inferredcites →https://doi.org/10.1001/archopht.1990.01070070075038openalex-snapshot
A Randomized Placebo-Controlled Trial of Cysteamine Eye Drops in Nephropathic Cystinosis
inferredcites →https://doi.org/10.1001/jama.281.3.249openalex-snapshot
Prevalence of Lysosomal Storage Disorders
inferredcites →https://doi.org/10.1006/mgme.1998.2725openalex-snapshot
A Randomized Clinical Trial of Topical Cysteamine Disulfide (Cystamine) versus Free Thiol (Cysteamine) in the Treatment of Corneal Cystine Crystals in Cystinosis
inferredcites →https://doi.org/10.1006/mgme.1998.2790openalex-snapshot
Identification and Detection of the Common 65-kb Deletion Breakpoint in the Nephropathic Cystinosis Gene (CTNS)
inferredcites →https://doi.org/10.1007/bf01805472openalex-snapshot
Cystinosis in the Federal Republic of Germany. Coordination and analysis of the data
inferredcites →https://doi.org/10.1007/s00467-003-1077-5openalex-snapshot
New aspects of the pathogenesis of cystinosis
inferredcites →https://doi.org/10.1007/s00467-011-1942-6openalex-snapshot
Genetic basis of cystinosis in Turkish patients: a single-center experience
inferredcites →https://doi.org/10.1007/s12098-015-2014-xopenalex-snapshot
Lysosomal Storage Disorders in Egyptian Children
inferredcites →https://doi.org/10.1016/j.ejpb.2008.04.010openalex-snapshot
Formulation and in vitro evaluation of cysteamine hydrochloride viscous solutions for the treatment of corneal cystinosis
inferredcites →https://doi.org/10.1016/j.ejpb.2013.04.017openalex-snapshot
Feasibility of corneal drug delivery of cysteamine using vitamin E modified silicone hydrogel contact lenses
inferredcites →https://doi.org/10.1016/j.ejpb.2016.07.009openalex-snapshot
Effect of pH and penetration enhancers on cysteamine stability and trans-corneal transport
inferredcites →https://doi.org/10.1016/j.ijpharm.2010.03.065openalex-snapshot
Gel formulations for treatment of the ophthalmic complications in cystinosis
inferredcites →https://doi.org/10.1016/j.ijpharm.2016.10.044openalex-snapshot
Preformulation of cysteamine gels for treatment of the ophthalmic complications in cystinosis
inferredcites →https://doi.org/10.1016/j.jpeds.2016.12.055openalex-snapshot
Ocular Complications of Infantile Nephropathic Cystinosis
inferredcites →https://doi.org/10.1016/j.survophthal.2006.10.006openalex-snapshot
Ophthalmic Manifestations and Histopathology of Infantile Nephropathic Cystinosis: Report of a Case and Review of the Literature
inferredcites →https://doi.org/10.1016/j.ymgme.2007.07.008openalex-snapshot
A review of the role of enhanced apoptosis in the pathophysiology of cystinosis
inferredcites →https://doi.org/10.1016/j.ymgme.2013.12.298openalex-snapshot
A new gel formulation of topical cysteamine for the treatment of corneal cystine crystals in cystinosis: The Cystadrops OCT-1 study
inferredcites →https://doi.org/10.1016/s0022-3468(05)80282-9openalex-snapshot
Renal transplantation for infantile cystinosis: Long-term follow-up
inferredcites →https://doi.org/10.1021/acs.molpharmaceut.6b00488openalex-snapshot
Synergistic Cysteamine Delivery Nanowafer as an Efficacious Treatment Modality for Corneal Cystinosis
inferredcites →https://doi.org/10.1038/eye.1991.139openalex-snapshot
A randomised placebo-controlled trial of topical cysteamine therapy in patients with nephropathic cystinosis
inferredcites →https://doi.org/10.1038/ng0498-319openalex-snapshot
A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis
inferredcites →https://doi.org/10.1038/sj.ejhg.5200349openalex-snapshot
Molecular Analysis of Cystinosis: Probable Irish Origin of the Most Common French Canadian Mutation
inferredcites →https://doi.org/10.1053/j.ajkd.2014.07.020openalex-snapshot
Patient and Graft Survival Following Kidney Transplantation in Recipients With Cystinosis: A Cohort Study
inferredcites →https://doi.org/10.1056/nejm198703263161304openalex-snapshot
Removal of Corneal Crystals by Topical Cysteamine in Nephropathic Cystinosis
inferredcites →https://doi.org/10.1056/nejmc1309480openalex-snapshot
Nephropathic Cystinosis — A Gap between Developing and Developed Nations
inferredcites →https://doi.org/10.1086/302118openalex-snapshot
CTNS Mutations in an American-Based Population of Cystinosis Patients
inferredcites →https://doi.org/10.1086/302509openalex-snapshot
Molecular Characterization of CTNS Deletions in Nephropathic Cystinosis: Development of a PCR-Based Detection Assay
inferredcites →https://doi.org/10.1089/jop.1996.12.499openalex-snapshot
The Penetration of Topical Cysteamine into the Human Eye
inferredcites →https://doi.org/10.1093/hmg/8.13.2507openalex-snapshot
Severity of phenotype in cystinosis varies with mutations in the CTNS gene: predicted effect on the model of cystinosin
inferredcites →https://doi.org/10.1093/hmg/ddh152openalex-snapshot
Molecular pathogenesis of cystinosis: effect of CTNS mutations on the transport activity and subcellular localization of cystinosin
inferredcites →https://doi.org/10.1097/00003226-200203000-00009openalex-snapshot
Age-Related Prevalence of Anterior Segment Complications in Patients With Infantile Nephropathic Cystinosis
inferredcites →https://doi.org/10.1101/gr.10.2.165openalex-snapshot
The Genomic Region Encompassing the Nephropathic Cystinosis Gene (CTNS): Complete Sequencing of a 200-kb Segment and Discovery of a Novel Gene within the Common Cystinosis-Causing Deletion
inferredcites →https://doi.org/10.1111/apa.12807openalex-snapshot
Epidemiology of lysosomal storage diseases in Sweden
inferredcites →https://doi.org/10.1111/j.1442-9071.2008.01886.xopenalex-snapshot
Clinicopathological features of ocular cystinosis
inferredcites →https://doi.org/10.1126/science.7112129openalex-snapshot
Cystine Transport Is Defective in Isolated Leukocyte Lysosomes from Patients with Cystinosis
inferredcites →https://doi.org/10.1136/bjo.75.5.311openalex-snapshot
Clearance of corneal crystals in nephropathic cystinosis by topical cysteamine 0.5%.
inferredcites →https://doi.org/10.1136/bjo.87.1.28openalex-snapshot
A multicentre randomised double masked clinical trial of a new formulation of topical cysteamine for the treatment of corneal cystine crystals in cystinosis
inferredcites →https://doi.org/10.1136/bjophthalmol-2016-309278openalex-snapshot
Efficacy of topical cysteamine in nephropathic cystinosis
inferredcites →https://doi.org/10.1136/jmg.13.6.434openalex-snapshot
Infantile cystinosis in France: genetics, incidence, geographic distribution.
inferredcites →https://doi.org/10.1136/jmg.35.5.366openalex-snapshot
A comparison of disease and gene frequencies of inborn errors of metabolism among different ethnic groups in the West Midlands, UK.
inferredcites →https://doi.org/10.1152/ajprenal.00318.2010openalex-snapshot
The pathogenesis of cystinosis: mechanisms beyond cystine accumulation
inferredcites →https://doi.org/10.1159/000153992openalex-snapshot
Hereditary Disorders in Saguenay-Lac-St-Jean (Quebec, Canada)
inferredcites →https://doi.org/10.1159/000245065openalex-snapshot
Report of a Brazilian Multicenter Study on Nephropathic Cystinosis
inferredcites →https://doi.org/10.1159/000301237openalex-snapshot
Chapter 14: Demography of the UK Paediatric Renal Replacement Therapy population in 2008
inferredcites →https://doi.org/10.1167/iovs.16-21080openalex-snapshot
A New Viscous Cysteamine Eye Drops Treatment for Ophthalmic Cystinosis: An Open-Label Randomized Comparative Phase III Pivotal Study
inferredcites →https://doi.org/10.1172/jci108448openalex-snapshot
Cystinosis. Intracellular cystine depletion by aminothiols in vitro and in vivo.
inferredcites →https://doi.org/10.1186/s13023-015-0307-9openalex-snapshot
Excellent long-term outcome of renal transplantation in cystinosis patients
inferredcites →https://doi.org/10.1586/17469899.2013.814885openalex-snapshot
Cysteamine ophthalmic solution 0.44% for the treatment of corneal cystine crystals in cystinosis
inferredcites →https://doi.org/10.1681/asn.v12102170openalex-snapshot
Characterization of a Putative Founder Mutation that Accounts for the High Incidence of Cystinosis in Brittany
inferredcites →https://doi.org/10.2147/opth.s36626openalex-snapshot
Treatment of corneal cystine crystal accumulation in patients with cystinosis
inferredcites →https://doi.org/10.2215/cjn.02000311openalex-snapshot
Improvement in the Renal Prognosis in Nephropathic Cystinosis
inferredcites →https://doi.org/10.3109/13816810903200953openalex-snapshot
Characterization ofCTNSmutations in Arab patients with Cystinosis
inferredcites →https://doi.org/10.4103/1319-2442.106315openalex-snapshot
Nephropathic cystinosis in a developing country: The Egyptian experience
inferredcites →https://doi.org/10.7326/0003-4819-147-4-200708210-00006openalex-snapshot
Nephropathic Cystinosis in Adults: Natural History and Effects of Oral Cysteamine Therapy
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/s40123-025-01170-7openalex-snapshot
The Use of a Viscous Cysteamine Eyedrop in a Belgian Cohort: Early 3-Year Results
inferred← citeshttps://doi.org/10.1016/j.ajo.2020.07.052openalex-snapshot
Efficacy and Safety of Topical Cysteamine in Corneal Cystinosis: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1016/j.bioadv.2022.213235openalex-snapshot
Thermo-responsive and mucoadhesive gels for the treatment of cystinosis
inferred← citeshttps://doi.org/10.1016/j.ejpb.2021.05.019openalex-snapshot
Gold nanoparticle synthesis in contact lenses for drug-less ocular cystinosis treatment
inferred← citeshttps://doi.org/10.1016/j.exer.2022.109338openalex-snapshot
The TGM2 Inhibitor Cysteamine Hydrochloride Does Not Impact Corneal Epithelial and Stromal Wound Healing in Vitro and in Vivo
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2018.08.006openalex-snapshot
Novel approaches for improving stability of cysteamine formulations
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.121992openalex-snapshot
Ocular biodistribution of cysteamine delivered by a sustained release microsphere/thermoresponsive gel eyedrop
inferred← citeshttps://doi.org/10.1016/j.nefro.2019.05.005openalex-snapshot
Implementación de un método para la cuantificación de cistina intraleucocitaria como apoyo diagnóstico para la cistinosis
inferred← citeshttps://doi.org/10.1016/j.nefroe.2019.05.006openalex-snapshot
Implementation of a method to quantify white blood cell cystine as a diagnostic support for cystinosis
inferred← citeshttps://doi.org/10.1016/j.yexmp.2025.104995openalex-snapshot
Therapeutic strategies in cystinosis: A focus on cysteamine and beyond
inferred← citeshttps://doi.org/10.1038/s41598-022-07750-yopenalex-snapshot
Development of a fibrin-mediated gene delivery system for the treatment of cystinosis via design of experiment
inferred← citeshttps://doi.org/10.1097/mnh.0000000000000934openalex-snapshot
Genetic testing in the evaluation of recipient candidates and living kidney donors
inferred← citeshttps://doi.org/10.1136/bjophthalmol-2016-309278openalex-snapshot
Efficacy of topical cysteamine in nephropathic cystinosis
inferred← citeshttps://doi.org/10.1136/bjophthalmol-2020-316450openalex-snapshot
Long-term follow-up of cystinosis patients treated with 0.55% cysteamine hydrochloride
inferred← citeshttps://doi.org/10.1177/1120672119848899openalex-snapshot
Ocular manifestations of intermediate cystinosis: To treat or not to treat?
inferred← citeshttps://doi.org/10.1177/11206721221078649openalex-snapshot
Analysis of tear film in cystinosis patients treated with topical viscous cysteamine hydrochloride (Cystadrops ® )
inferred← citeshttps://doi.org/10.1186/s12886-020-01336-wopenalex-snapshot
Examination of corneal deposits in nephropathic cystinosis using in vivo confocal microscopy and anterior segment optical coherence tomography: an age-dependent cross sectional study
inferred← citeshttps://doi.org/10.12659/ajcr.916737openalex-snapshot
Asymmetrical Ocular Manifestations of Nephropathic Cystinosis; A Case Report
inferred← citeshttps://doi.org/10.1556/650.2022.32484openalex-snapshot
Ciszteamintartalmú szemcsepp alkalmazása cystinosisban
inferred← citeshttps://doi.org/10.2147/opth.s479770openalex-snapshot
An Open-Label, Phase III Study to Assess the Efficacy and Safety of Cysteamine Ophthalmic Solution 0.55% in Japanese Cystinosis Patients
inferred← citeshttps://doi.org/10.3390/biomedinformatics6020011openalex-snapshot
Artificial Intelligence in Corneal Drug Delivery Systems
inferred← citeshttps://doi.org/10.3390/diagnostics10110911openalex-snapshot
Ophthalmic Evaluation of Diagnosed Cases of Eye Cystinosis: A Tertiary Care Center’s Experience
inferred← citeshttps://doi.org/10.3390/ph15010002openalex-snapshot
Limitations and Challenges in the Stability of Cysteamine Eye Drop Compounded Formulations
inferred← citeshttps://doi.org/10.3390/ph16081146openalex-snapshot
Oxidative Stress and Antioxidant-Based Interventional Medicine in Ophthalmology
inferred← citeshttps://doi.org/10.3390/pharmaceutics12121177openalex-snapshot
Recent Research in Ocular Cystinosis: Drug Delivery Systems, Cysteamine Detection Methods and Future Perspectives
inferred← citeshttps://doi.org/10.3390/pharmaceutics14102194openalex-snapshot
Cysteamine Eye Drops in Hyaluronic Acid Packaged in Innovative Single-Dose Systems: Stability and Ocular Biopermanence
inferred← citeshttps://doi.org/10.3390/pharmaceutics16081052openalex-snapshot
Development and Evaluation of Different Electrospun Cysteamine-Loaded Nanofibrous Webs: A Promising Option for Treating a Rare Lysosomal Storage Disorder
inferred← citeshttps://doi.org/10.3892/mi.2025.242openalex-snapshot
Pediatric cystinosis: Corneal cystine deposits and papilledema in a 4‑year‑old: A case report
inferred← citeshttps://doi.org/10.4274/tjo.galenos.2024.89957openalex-snapshot
Ocular Involvement in Patients with Infantile Nephropathic Cystinosis
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