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Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest

https://doi.org/10.2147/ott.s166018
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/ar.21517openalex-snapshot
Anticancer Potential of Euphorbia helioscopia L Extracts Against Human Cancer Cells
inferredcites →https://doi.org/10.1007/3-540-06873-2_15openalex-snapshot
Molecular approaches for designing antiviral and antitumor compounds
inferredcites →https://doi.org/10.1007/bf02673865openalex-snapshot
Cyclin/cdk complexes: Their involvement in cell cycle progression and mitotic division
inferredcites →https://doi.org/10.1016/j.bcp.2010.07.013openalex-snapshot
Human papillomavirus type 16 E5 oncoprotein as a new target for cervical cancer treatment
inferredcites →https://doi.org/10.1016/j.canlet.2010.07.015openalex-snapshot
Targeting apoptosis pathways in cancer by Chinese medicine
inferredcites →https://doi.org/10.1016/j.canlet.2011.01.013openalex-snapshot
Targeting apoptosis pathways in cancer stem cells
inferredcites →https://doi.org/10.1016/j.ccr.2005.06.012openalex-snapshot
Killing cancer cells by flipping the Bcl-2/Bax switch
inferredcites →https://doi.org/10.1016/j.molmed.2007.07.001openalex-snapshot
From traditional Chinese medicine to rational cancer therapy
inferredcites →https://doi.org/10.1016/j.tcb.2013.07.006openalex-snapshot
Evading apoptosis in cancer
inferredcites →https://doi.org/10.1016/j.tiv.2014.02.002openalex-snapshot
Involvement of extrinsic and intrinsic apoptotic pathways together with endoplasmic reticulum stress in cell death induced by naphthylchalcones in a leukemic cell line: Advantages of multi-target action
inferredcites →https://doi.org/10.1016/s0065-230x(08)60102-5openalex-snapshot
Human Papillomaviruses and cervical Cancer
inferredcites →https://doi.org/10.1016/s0140-6736(03)13778-6openalex-snapshot
Cervical cancer
inferredcites →https://doi.org/10.1016/s0959-8049(01)00352-5openalex-snapshot
Chemoradiotherapy for cervical cancer
inferredcites →https://doi.org/10.1038/35037710openalex-snapshot
The biochemistry of apoptosis
inferredcites →https://doi.org/10.1038/35077213openalex-snapshot
Proliferation, cell cycle and apoptosis in cancer
inferredcites →https://doi.org/10.1038/nrc2248openalex-snapshot
The impact of a negligent G2/M checkpoint on genomic instability and cancer induction
inferredcites →https://doi.org/10.1038/sj.cdd.4400476openalex-snapshot
Emerging roles of caspase-3 in apoptosis
inferredcites →https://doi.org/10.1046/j.1432-1327.1998.2520001.xopenalex-snapshot
Mitochondria and apoptosis
inferredcites →https://doi.org/10.1080/14786419.2011.622275openalex-snapshot
Analysis of euphornin inEuphorbia helioscopiaL. and its cytotoxicity to mice lung adenocarcinoma cells (LA795)
inferredcites →https://doi.org/10.1093/carcin/bgh180openalex-snapshot
Silibinin causes cell cycle arrest and apoptosis in human bladder transitional cell carcinoma cells by regulating CDKI-CDK-cyclin cascade, and caspase 3 and PARP cleavages
inferredcites →https://doi.org/10.1093/emboj/16.3.545openalex-snapshot
Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation
inferredcites →https://doi.org/10.1111/j.1745-7270.2005.00108.xopenalex-snapshot
Caspase Family Proteases and Apoptosis
inferredcites →https://doi.org/10.1126/science.281.5381.1309openalex-snapshot
Mitochondria and Apoptosis
inferredcites →https://doi.org/10.1126/science.7878464openalex-snapshot
Apoptosis in the Pathogenesis and Treatment of Disease
inferredcites →https://doi.org/10.1159/000477308openalex-snapshot
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
inferredcites →https://doi.org/10.1529/biophysj.105.068122openalex-snapshot
Bistability in Apoptosis: Roles of Bax, Bcl-2, and Mitochondrial Permeability Transition Pores
inferredcites →https://doi.org/10.3892/mco.2014.324openalex-snapshot
Candidate biomarkers for cervical cancer treatment: Potential for clinical practice (Review)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112649zenodo-depositor-declared
Euphorbia helioscopia L.: A phytochemical and pharmacological overview
inferred← citeshttps://doi.org/10.1016/j.sajb.2024.08.049openalex-snapshot
Evaluation of bioactive compounds, antioxidant and antimicrobial properties of Bulbophyllum griffithii (Lindl.) Rchb.f., an unexplored rare orchid of therapeutic importance
inferred← citeshttps://doi.org/10.1038/s41598-023-49995-1openalex-snapshot
LC–MS profiling, in vitro and in silico C-ABL kinase inhibitory approach to identify potential anticancer agents from Dalbergia sissoo leaves
inferred← citeshttps://doi.org/10.1038/s41598-025-04522-2openalex-snapshot
Investigation of the mechanism of euphornin against cervical cancer using network pharmacology
inferred← citeshttps://doi.org/10.1111/ppl.70257openalex-snapshot
Genetic modification of Water spinach (Ipomoea aquatica), a genoprotective perennial leafy green
inferred← citeshttps://doi.org/10.1177/1934578x20953249openalex-snapshot
Chemical Composition and Antimicrobial Activity of the Essential Oil From Euphorbia helioscopia L.
inferred← citeshttps://doi.org/10.13189/azb.2024.120106openalex-snapshot
Select Phytocompounds from Cocculus hirsutus (L.) W. Theob. Extract Having Anti-Cancer Potential as Identified by LC-MS and in Silico Studies
inferred← citeshttps://doi.org/10.15212/amm-2024-0050openalex-snapshot
Preliminary study on Zeqi: from pharmacological action of active ingredients to clinical application research
inferred← citeshttps://doi.org/10.2147/ijgm.s395553openalex-snapshot
Comprehensive Analysis Reveals Distinct Immunological and Prognostic Characteristics of CD276/B7-H3 in Pan-Cancer
inferred← citeshttps://doi.org/10.3389/fnut.2023.1304903openalex-snapshot
Chemical and biochemical characterization of Ipomoea aquatica: genoprotective potential and inhibitory mechanism of its phytochemicals against α-amylase and α-glucosidase
inferred← citeshttps://doi.org/10.3892/or.2022.8288openalex-snapshot
Inhibition of LDHA suppresses cell proliferation and increases mitochondrial apoptosis via the JNK signaling pathway in cervical cancer cells
inferred← citeshttps://doi.org/10.4103/japtr.japtr_210_25openalex-snapshot
Bioactivity assessment of methanolic extract of Rhododendron cowanianum: An endemic species of Nepal
inferred← citeshttps://doi.org/10.4103/japtr.japtr_235_25openalex-snapshot
Bioactive potential of Rhododendron lowndesii: Extraction, antioxidant analysis, antimicrobial assay, and Liquid Chromatography-mass Spectrometry profiling
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