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Role of ACAT1-positive late endosomes in macrophages: Cholesterol metabolism and therapeutic applications for Niemann-Pick disease type C

https://doi.org/10.2152/jmi.61.270

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Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.ymgme.2012.11.005openalex-snapshot

Effects of cyclodextrin in two patients with Niemann–Pick Type C disease

inferredcites →https://doi.org/10.1016/s0002-9440(10)64723-2openalex-snapshot

Localization of Human Acyl-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) in Macrophages and in Various Tissues

inferredcites →https://doi.org/10.1016/s0021-9258(19)36846-2openalex-snapshot

Molecular cloning and functional expression of human acyl-coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese hamster ovary cells.

inferredcites →https://doi.org/10.1038/ncb1035openalex-snapshot

The endoplasmic reticulum is the site of cholesterol-induced cytotoxicity in macrophages

inferredcites →https://doi.org/10.1038/nri3520openalex-snapshot

Macrophages in atherosclerosis: a dynamic balance

inferredcites →https://doi.org/10.1073/pnas.0810895106openalex-snapshot

Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1 −/− mouse

inferredcites →https://doi.org/10.1073/pnas.0914309107openalex-snapshot

Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells

inferredcites →https://doi.org/10.1074/jbc.273.41.26747openalex-snapshot

Identification of a Form of Acyl-CoA:Cholesterol Acyltransferase Specific to Liver and Intestine in Nonhuman Primates

inferredcites →https://doi.org/10.1074/jbc.m003927200openalex-snapshot

Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine

inferredcites →https://doi.org/10.1074/jbc.m300542200openalex-snapshot

Distinct Endosomal Compartments in Early Trafficking of Low Density Lipoprotein-derived Cholesterol

inferredcites →https://doi.org/10.1074/jbc.m407167200openalex-snapshot

Macropinocytosis Is the Endocytic Pathway That Mediates Macrophage Foam Cell Formation with Native Low Density Lipoprotein

inferredcites →https://doi.org/10.1097/00041433-199310000-00003openalex-snapshot

The role of macrophages in atherogenesis

inferredcites →https://doi.org/10.1097/00062752-200001000-00009openalex-snapshot

Niemann-Pick disease

inferredcites →https://doi.org/10.1097/01.lab.0000095687.17383.39openalex-snapshot

Acyl-Coenzyme A:Cholesterol Acyltransferase 2 (ACAT2) Is Induced in Monocyte-Derived Macrophages: In Vivo and In Vitro Studies

inferredcites →https://doi.org/10.1146/annurev.cellbio.22.010305.104656openalex-snapshot

Cholesterol Sensing, Trafficking, and Esterification

inferredcites →https://doi.org/10.1172/jci10310openalex-snapshot

Increased atherosclerosis in LDL receptor–null mice lacking ACAT1 in macrophages

inferredcites →https://doi.org/10.1267/ahc.13033openalex-snapshot

ACAT1-associated Late Endosomes/Lysosomes Significantly Improve Impaired Intracellular Cholesterol Metabolism and the Survival of Niemann-Pick Type C Mice

inferredcites →https://doi.org/10.5551/jat.4416openalex-snapshot

Association of ACAT1-Positive Vesicles with Late Endosomes/ Lysosomes in Cholesterol-Rich Human Macrophages

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4760648openalex-extracted

Cholesterol Metabolism-Mediated Immune Regulation and Cancer Immunotherapy

inferred← citeshttps://doi.org/10.1016/j.cbpb.2017.12.001openalex-snapshot

Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation

inferred← citeshttps://doi.org/10.1186/s12864-018-5345-yopenalex-snapshot

Gene co-expression networks associated with carcass traits reveal new pathways for muscle and fat deposition in Nelore cattle

inferred← citeshttps://doi.org/10.1515/hmbci-2018-0024openalex-snapshot

Circulating low density lipoprotein (LDL)

inferred← citeshttps://doi.org/10.3389/fmed.2022.815467openalex-snapshot

Metabolomic Analysis Uncovers Lipid and Amino Acid Metabolism Disturbance During the Development of Ascites in Alcoholic Liver Disease

inferred← citeshttps://doi.org/10.3390/ijms19040972openalex-snapshot

Evaluation of Two Liver Treatment Strategies in a Mouse Model of Niemann–Pick-Disease Type C1

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