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Mitochondrial Dysfunction and Lipid Homeostasis

https://doi.org/10.2174/138920012803762792
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Outgoing claims: the papers this work cites, builds on, or argues with.

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The mitochondrial antioxidant defence system and its response to oxidative stress
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Fatty acid synthase: A metabolic oncogene in prostate cancer?
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The tyrosine kinase receptor HER2 (erbB‐2): From oncogenesis to adipogenesis
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Metabolic alterations and targeted therapies in prostate cancer
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Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity
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Topology of Hepatic Mitochondrial Carnitine Palmitoyltransferase I
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Mitochondrial Genetics and Cancer
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inferredcites →https://doi.org/10.1007/s00246-011-9889-8openalex-snapshot
Peroxisome Proliferator Activated Receptor-Alpha (PPARα) and PPAR Gamma Coactivator-1alpha (PGC-1α) Regulation of Cardiac Metabolism in Diabetes
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A general introduction to the biochemistry of mitochondrial fatty acid β‐oxidation
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Role of Fatty Acid Binding Proteins and Long Chain Fatty Acids in Modulating Nuclear Receptors and Gene Transcription
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Metabolic syndrome associated with HIV and highly active antiretroviral therapy
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The Role of Mitochondria in Glioma Pathophysiology
inferredcites →https://doi.org/10.1016/j.abb.2009.09.011openalex-snapshot
Triacylglycerol-induced impairment in mitochondrial biogenesis and function in J774.2 and mouse peritoneal macrophage foam cells
inferredcites →https://doi.org/10.1016/j.arcmed.2005.11.012openalex-snapshot
Oxidative Stress at the Vascular Wall. Mechanistic and Pharmacological Aspects
inferredcites →https://doi.org/10.1016/j.atherosclerosis.2005.10.005openalex-snapshot
Impact of oxidized low density lipoprotein on vascular cells
inferredcites →https://doi.org/10.1016/j.bbabio.2010.02.035openalex-snapshot
The regulation and turnover of mitochondrial uncoupling proteins
inferredcites →https://doi.org/10.1016/j.bbabio.2010.04.001openalex-snapshot
Lipotoxicity, fatty acid uncoupling and mitochondrial carrier function
inferredcites →https://doi.org/10.1016/j.bbalip.2007.02.012openalex-snapshot
Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter
inferredcites →https://doi.org/10.1016/j.bbalip.2007.06.003openalex-snapshot
Statins and foam cell formation: Impact on LDL oxidation and uptake of oxidized lipoproteins via scavenger receptors
inferredcites →https://doi.org/10.1016/j.bbalip.2009.09.005openalex-snapshot
Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: Molecular mechanisms and therapeutic perspectives
inferredcites →https://doi.org/10.1016/j.bbalip.2009.09.011openalex-snapshot
Mitochondrial dysfunction and lipotoxicity
inferredcites →https://doi.org/10.1016/j.bbalip.2009.09.017openalex-snapshot
Lipotoxicity in macrophages: evidence from diseases associated with the metabolic syndrome
inferredcites →https://doi.org/10.1016/j.bbamcr.2006.05.003openalex-snapshot
Activation of superoxide dismutases: Putting the metal to the pedal
inferredcites →https://doi.org/10.1016/j.bbrc.2007.03.045openalex-snapshot
Gpx4 protects mitochondrial ATP generation against oxidative damage
inferredcites →https://doi.org/10.1016/j.bbrc.2009.05.085openalex-snapshot
Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells
inferredcites →https://doi.org/10.1016/j.biocel.2009.02.005openalex-snapshot
Importance of lipid metabolism for intracellular and mitochondrial membrane fusion/fission processes
inferredcites →https://doi.org/10.1016/j.biocel.2009.04.010openalex-snapshot
Structural and functional link between the mitochondrial network and the endoplasmic reticulum
inferredcites →https://doi.org/10.1016/j.cardiores.2006.08.023openalex-snapshot
The PPAR regulatory system in cardiac physiology and disease
inferredcites →https://doi.org/10.1016/j.cca.2010.08.038openalex-snapshot
Mechanisms of LDL oxidation
inferredcites →https://doi.org/10.1016/j.ceca.2010.10.004openalex-snapshot
Uncoupling protein 3 adjusts mitochondrial Ca2+ uptake to high and low Ca2+ signals
inferredcites →https://doi.org/10.1016/j.exger.2010.01.003openalex-snapshot
The sites and topology of mitochondrial superoxide production
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2004.10.037openalex-snapshot
Nitroxia: The pathological consequence of dysfunction in the nitric oxide–cytochrome c oxidase signaling pathway
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2005.01.015openalex-snapshot
Mechanism underlying oxidative stress-mediated lipotoxicity: Exposure of J774.2 macrophages to triacylglycerols facilitates mitochondrial reactive oxygen species production and cellular necrosis
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2005.02.014openalex-snapshot
Mitochondrial dysfunction in cardiovascular disease
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2009.09.009openalex-snapshot
Oxidative risk for atherothrombotic cardiovascular disease
inferredcites →https://doi.org/10.1016/j.gde.2009.10.009openalex-snapshot
HIF-1: upstream and downstream of cancer metabolism
inferredcites →https://doi.org/10.1016/j.jnutbio.2010.01.005openalex-snapshot
Liver fatty acid-binding protein and obesity
inferredcites →https://doi.org/10.1016/j.mce.2006.12.002openalex-snapshot
Mechanism of StAR's regulation of mitochondrial cholesterol import
inferredcites →https://doi.org/10.1016/j.mce.2010.07.005openalex-snapshot
TNF-α induces mitochondrial dysfunction in 3T3-L1 adipocytes
inferredcites →https://doi.org/10.1016/j.mito.2004.07.027openalex-snapshot
Mitochondrial dysfunction in cancer
inferredcites →https://doi.org/10.1016/j.nut.2007.10.017openalex-snapshot
Lipotoxic effects of triacylglycerols in J774.2 macrophages
inferredcites →https://doi.org/10.1016/j.pathophys.2006.05.002openalex-snapshot
Oxidative stress and atherosclerosis
inferredcites →https://doi.org/10.1016/j.pneurobio.2004.11.003openalex-snapshot
Antiepileptic popular ketogenic diet: emerging twists in an ancient story
inferredcites →https://doi.org/10.1016/j.tcb.2007.07.011openalex-snapshot
Mitochondria–endoplasmic reticulum choreography: structure and signaling dynamics
inferredcites →https://doi.org/10.1016/j.tem.2009.04.001openalex-snapshot
Mitochondrial generation of free radicals and hypoxic signaling
inferredcites →https://doi.org/10.1016/j.tips.2005.02.005openalex-snapshot
Mitochondrial nitric oxide synthase
inferredcites →https://doi.org/10.1016/j.yjmcc.2009.05.013openalex-snapshot
Oxidative stress and cardiovascular disease: Novel tools give (free) radical insight
inferredcites →https://doi.org/10.1016/s0143416002001872openalex-snapshot
Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria
inferredcites →https://doi.org/10.1016/s0278-6915(99)00090-3openalex-snapshot
Intracellular Antioxidants: from Chemical to Biochemical Mechanisms
inferredcites →https://doi.org/10.1016/s0891-5849(02)00905-xopenalex-snapshot
Superoxide dismutase multigene family: a comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression
inferredcites →https://doi.org/10.1016/s0891-5849(02)01197-8openalex-snapshot
Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells
inferredcites →https://doi.org/10.1016/s0891-5849(03)00239-9openalex-snapshot
Beyond LDL oxidation: ROS in vascular signal transduction
inferredcites →https://doi.org/10.1016/s0891-5849(03)00510-0openalex-snapshot
Mitochondrial nitric oxide synthase is not eNOS, nNOS or iNOS
inferredcites →https://doi.org/10.1016/s0899-9007(99)00266-xopenalex-snapshot
Fatty-acid synthase and human cancer: new perspectives on its role in tumor biology
inferredcites →https://doi.org/10.1038/cr.2009.69openalex-snapshot
Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis
inferredcites →https://doi.org/10.1038/ijo.2008.123openalex-snapshot
Regulation of food intake and energy expenditure by hypothalamic malonyl-CoA
inferredcites →https://doi.org/10.1038/nrd2222openalex-snapshot
Peroxynitrite: biochemistry, pathophysiology and development of therapeutics
inferredcites →https://doi.org/10.1038/nrm2391openalex-snapshot
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
inferredcites →https://doi.org/10.1038/sj.onc.1209607openalex-snapshot
Mitochondrial mutations in cancer
inferredcites →https://doi.org/10.1042/bj20091541openalex-snapshot
Mitochondrial peroxiredoxin involvement in antioxidant defence and redox signalling
inferredcites →https://doi.org/10.1042/bj20101680openalex-snapshot
Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase
inferredcites →https://doi.org/10.1042/bj2630313openalex-snapshot
Fuel selection and carbon flux during the starved-to-fed transition
inferredcites →https://doi.org/10.1042/bj2920907openalex-snapshot
Interaction of acyl-CoA binding protein (ACBP) on processes for which acyl-CoA is a substrate, product or inhibitor
inferredcites →https://doi.org/10.1042/bse0470053openalex-snapshot
Mitochondrial proton and electron leaks
inferredcites →https://doi.org/10.1073/pnas.0403390101openalex-snapshot
Inhibition of fatty acid synthase (FAS) suppresses HER2/neu ( erb B-2) oncogene overexpression in cancer cells
inferredcites →https://doi.org/10.1073/pnas.84.2.378openalex-snapshot
Malonyl-CoA binding site and the overt carnitine palmitoyltransferase activity reside on the opposite sides of the outer mitochondrial membrane.
inferredcites →https://doi.org/10.1074/jbc.m407258200openalex-snapshot
Mitochondrial Reactive Oxygen Species Control the Transcription Factor CHOP-10/GADD153 and Adipocyte Differentiation
inferredcites →https://doi.org/10.1074/jbc.r600016200openalex-snapshot
The Role of Hypothalamic Malonyl-CoA in Energy Homeostasis
inferredcites →https://doi.org/10.1089/ars.2009.2531openalex-snapshot
Mitochondrial Dysfunction in Diabetes: From Molecular Mechanisms to Functional Significance and Therapeutic Opportunities
inferredcites →https://doi.org/10.1089/ars.2009.2695openalex-snapshot
Mitochondrial Glutathione, a Key Survival Antioxidant
inferredcites →https://doi.org/10.1093/jn/126.suppl_4.1053sopenalex-snapshot
The Role of Oxidized Low Density Lipoprotein in Atherogenesis
inferredcites →https://doi.org/10.1093/jn/130.2.294sopenalex-snapshot
Role of Acyl-CoA Binding Protein in Acyl-CoA Metabolism and Acyl-CoA–Mediated Cell Signaling
inferredcites →https://doi.org/10.1111/j.1365-2184.2007.00498.xopenalex-snapshot
Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells
inferredcites →https://doi.org/10.1111/j.1530-0277.2008.00827.xopenalex-snapshot
Molecular Mechanisms of Alcoholic Fatty Liver
inferredcites →https://doi.org/10.1111/j.1742-4658.2010.07978.xopenalex-snapshot
Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity
inferredcites →https://doi.org/10.1111/j.1749-6632.2001.tb03943.xopenalex-snapshot
Scavenger Receptors, Oxidized LDL, and Atherosclerosis
inferredcites →https://doi.org/10.1111/j.1749-6632.2010.05616.xopenalex-snapshot
A novel function of mtDNA: its involvement in metastasis
inferredcites →https://doi.org/10.1113/jphysiol.2003.049478openalex-snapshot
Mitochondrial formation of reactive oxygen species
inferredcites →https://doi.org/10.1126/science.1104343openalex-snapshot
Mitochondrial Dysfunction and Type 2 Diabetes
inferredcites →https://doi.org/10.1139/o09-168openalex-snapshot
Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assemblyThis paper is one of a selection of papers published in this special issue entitled “Canadian Society of Biochemistry, Molecular & Cellular Biology 52nd Annual Meeting…
inferredcites →https://doi.org/10.1139/y09-135openalex-snapshot
Mechanisms associated with mitochondrial-generated reactive oxygen species in cancerThis article is one of a selection of papers published in a Special Issue on Oxidative Stress in Health and Disease.
inferredcites →https://doi.org/10.1152/ajpendo.90958.2008openalex-snapshot
Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis
inferredcites →https://doi.org/10.1155/2008/253817openalex-snapshot
The PPARα‐PGC‐1α Axis Controls Cardiac Energy Metabolism in Healthy and Diseased Myocardium
inferredcites →https://doi.org/10.1158/0008-5472.can-05-4673openalex-snapshot
Fatty Acid Synthase and Cancer: New Application of an Old Pathway
inferredcites →https://doi.org/10.1158/0008-5472.can-09-1550openalex-snapshot
An RNA Interference Screen Identifies Metabolic Regulators NR1D1 and PBP as Novel Survival Factors for Breast Cancer Cells with the ERBB2 Signature
inferredcites →https://doi.org/10.1161/01.res.0000248212.86638.e9openalex-snapshot
Free Radicals, Mitochondria, and Oxidized Lipids
inferredcites →https://doi.org/10.1172/jci26640openalex-snapshot
Restoration of hypothalamic lipid sensing normalizes energy and glucose homeostasis in overfed rats
inferredcites →https://doi.org/10.1186/1471-2407-11-56openalex-snapshot
Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells
inferredcites →https://doi.org/10.1186/bcr2240openalex-snapshot
Peroxisome proliferator-activated receptor-γ protects ERBB2-positive breast cancer cells from palmitate toxicity
inferredcites →https://doi.org/10.1186/bcr2777openalex-snapshot
Fatty acid synthase phosphorylation: a novel therapeutic target in HER2-overexpressing breast cancer cells
inferredcites →https://doi.org/10.1210/me.2007-0538openalex-snapshot
Hypothalamic Malonyl-Coenzyme A and the Control of Energy Balance
inferredcites →https://doi.org/10.1373/clinchem.2007.100156openalex-snapshot
The Perfect Storm: Obesity, Adipocyte Dysfunction, and Metabolic Consequences
inferredcites →https://doi.org/10.1677/joe-09-0359openalex-snapshot
PPAR control: it's SIRTainly as easy as PGC
inferredcites →https://doi.org/10.2174/092986708784534956openalex-snapshot
How Insulin Receptor Substrate Proteins Regulate the Metabolic Capacity of the Liver - Implications for Health and Disease
inferredcites →https://doi.org/10.2174/138161207781039661openalex-snapshot
Visceral Fat as Target of Highly Active Antiretroviral Therapy-Associated Metabolic Syndrome
inferredcites →https://doi.org/10.2337/diab.45.3.273openalex-snapshot
Are the β-Cell Signaling Molecules Malonyl-CoA and Cystolic Long-Chain Acyl-CoA Implicated in Multiple Tissue Defects of Obesity and NIDDM?
inferredcites →https://doi.org/10.2337/diabetes.54.suppl_2.s97openalex-snapshot
Mechanisms of Pancreatic β-Cell Death in Type 1 and Type 2 Diabetes
inferredcites →https://doi.org/10.2353/ajpath.2009.081155openalex-snapshot
Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations
inferredcites →https://doi.org/10.2478/v10039-009-0035-2openalex-snapshot
Role of adipokines in complications related to obesity. A review
inferredcites →https://doi.org/10.3233/jad-2010-100495openalex-snapshot
Is Alzheimer's Disease a Disorder of Mitochondria-Associated Membranes?
inferredcites →https://doi.org/10.3892/ijo_00000455openalex-snapshot
Fatty acid synthase activity regulates HER2 extracellular domain shedding into the circulation of HER2-positive metastatic breast cancer patients
inferredcites →https://doi.org/10.3892/ijo_00000725openalex-snapshot
Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: A mechanistic model supporting prevention strategies
inferredcites →https://doi.org/10.3945/ajcn.2009.28449copenalex-snapshot
Adiponectin in insulin resistance: lessons from translational research
inferredcites →https://doi.org/10.4161/cc.8.18.9505openalex-snapshot
The hypothalamus bridges the gap between physiology and biochemistry in high-fat diet-induced hepatic insulin resistance
inferredcites →https://doi.org/10.5551/jat.3939openalex-snapshot
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Effects of intermittent fasting regimens on glycemic, hepatic, anthropometric, and clinical markers in patients with non-alcoholic fatty liver disease: Systematic review and meta-analysis of randomized controlled trials
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Aminooxyacetic acid ameliorates alcohol-induced learning and memory deficits through BDNF-TrkB pathway and calcium homeostasis
inferred← citeshttps://doi.org/10.1213/ane.0000000000002773openalex-snapshot
The Effects of Agrin Isoforms on Diabetic Neuropathic Pain in a Rat Streptozotocin Model
inferred← citeshttps://doi.org/10.1371/journal.pgen.1006152openalex-snapshot
A High Temperature-Dependent Mitochondrial Lipase EXTRA GLUME1 Promotes Floral Phenotypic Robustness against Temperature Fluctuation in Rice (Oryza sativa L.)
inferred← citeshttps://doi.org/10.1530/joe-17-0190openalex-snapshot
Anti-inflammatory effects of exercise training in adipose tissue do not require FGF21
inferred← citeshttps://doi.org/10.15698/mic2014.07.156openalex-snapshot
Sphingolipids and mitochondrial function, lessons learned from yeast
inferred← citeshttps://doi.org/10.17533/udea.iatreia.15098openalex-snapshot
Estudio de la deficiencia de acil-CoA deshidrogenasa de cadena muy larga con cardiomiopatía mediante el uso de un sustrato deuterado
inferred← citeshttps://doi.org/10.18632/aging.101204openalex-snapshot
Mouse mitochondrial lipid composition is defined by age in brain and muscle
inferred← citeshttps://doi.org/10.18632/oncotarget.9835openalex-snapshot
Crosstalk between osteoprotegerin (OPG), fatty acid synthase (FASN) and, cycloxygenase-2 (COX-2) in breast cancer: implications in carcinogenesis
inferred← citeshttps://doi.org/10.21203/rs.3.rs-10539896/v1openalex-snapshot
A novel multisystem approach uncovers conserved mitochondrial complex I disease phenotypes and suppressors
inferred← citeshttps://doi.org/10.2147/cmar.s255817openalex-snapshot
Aberrant Expression of Citrate Synthase is Linked to Disease Progression and Clinical Outcome in Prostate Cancer
inferred← citeshttps://doi.org/10.2174/0929867322666150729114036openalex-snapshot
Mitochondria-Mediated Oxidative Stress: Old Target for New Drugs
inferred← citeshttps://doi.org/10.3389/fendo.2023.1267170openalex-snapshot
Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism
inferred← citeshttps://doi.org/10.3389/fphar.2025.1546878openalex-snapshot
Predicting new-onset stroke with machine learning: development of a model integrating traditional Chinese and western medicine
inferred← citeshttps://doi.org/10.3389/fphys.2020.01050openalex-snapshot
Dyslipidemia in Kidney Disorders: Perspectives on Mitochondria Homeostasis and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.3390/antiox10101602openalex-snapshot
Oxidative Stress Linked Organ Lipid Hydroperoxidation and Dysregulation in Mouse Model of Nonalcoholic Steatohepatitis: Revealed by Lipidomic Profiling of Liver and Kidney
inferred← citeshttps://doi.org/10.3390/antiox13121540openalex-snapshot
From Adipose to Ailing Kidneys: The Role of Lipid Metabolism in Obesity-Related Chronic Kidney Disease
inferred← citeshttps://doi.org/10.3390/biom16081126openalex-snapshot
ALS: An Organism-Wide Bioenergetic Failure Due to Mitochondrial Dysfunctions?
inferred← citeshttps://doi.org/10.3390/biomedicines11092416openalex-snapshot
SAMM50-rs2073082, -rs738491 and -rs3761472 Interactions Enhancement of Susceptibility to Non-Alcoholic Fatty Liver Disease
inferred← citeshttps://doi.org/10.3390/diseases12110277openalex-snapshot
Mitochondrial Dysfunction and Risk Factors for Noncommunicable Diseases: From Basic Concepts to Future Prospective
inferred← citeshttps://doi.org/10.3390/ijms20194924openalex-snapshot
The Role of Adipose Tissue Mitochondria: Regulation of Mitochondrial Function for the Treatment of Metabolic Diseases
inferred← citeshttps://doi.org/10.3390/ijms26020752openalex-snapshot
Type 2 Diabetes Induces Mitochondrial Dysfunction in Zebrafish Skeletal Muscle Leading to Diabetic Myopathy via the miR-139-5p/NAMPT Pathway
inferred← citeshttps://doi.org/10.3390/ma14154180openalex-snapshot
Fluorescent Materials for Monitoring Mitochondrial Biology
inferred← citeshttps://doi.org/10.37349/edd.2024.00057openalex-snapshot
Impact of mitochondrial lipid alterations on liver disease mechanisms and progression
inferred← citeshttps://doi.org/10.4093/dmj.2023.0275openalex-snapshot
PDZD8 Augments Endoplasmic Reticulum-Mitochondria Contact and Regulates Ca2+ Dynamics and Cypd Expression to Induce Pancreatic β-Cell Death during Diabetes
inferred← citeshttps://doi.org/10.4330/wjc.v18.i4.117929openalex-snapshot
Daming capsule combined with SGLT2i confers protection against diabetes with myocardial ischemia/reperfusion injury induced ferroptosis via AMPK
inferred← citeshttps://doi.org/10.5551/jat.24398openalex-snapshot
Antioxidant Effects of Statins in the Management of Cardiometabolic Disorders
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