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The Impact of Indoleamine 2,3-dioxygenase (IDO) Expression on Stage III Gastric Cancer

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/j.1460-2075.1992.tb05481.xopenalex-snapshot
Induced expression of PD‐1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.
inferredcites →https://doi.org/10.1007/s10120-011-0041-5openalex-snapshot
Japanese classification of gastric carcinoma: 3rd English edition
inferredcites →https://doi.org/10.1007/s10120-015-0519-7openalex-snapshot
Programmed cell death protein 1 expression is an independent prognostic factor in gastric cancer after curative resection
inferredcites →https://doi.org/10.1007/s10555-012-9395-3openalex-snapshot
The role of FOXP3 in the development and metastatic spread of breast cancer
inferredcites →https://doi.org/10.1016/j.immuni.2005.03.013openalex-snapshot
GCN2 Kinase in T Cells Mediates Proliferative Arrest and Anergy Induction in Response to Indoleamine 2,3-Dioxygenase
inferredcites →https://doi.org/10.1016/j.immuni.2015.11.024openalex-snapshot
Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy
inferredcites →https://doi.org/10.1016/s1470-2045(16)30406-5openalex-snapshot
Predictive biomarkers for checkpoint inhibitor-based immunotherapy
inferredcites →https://doi.org/10.1038/bjc.2011.513openalex-snapshot
Clinicopathological significance of indoleamine 2,3-dioxygenase 1 expression in colorectal cancer
inferredcites →https://doi.org/10.1038/ni846openalex-snapshot
CTLA-4–Ig regulates tryptophan catabolism in vivo
inferredcites →https://doi.org/10.1038/srep21319openalex-snapshot
Increased expression of IDO associates with poor postoperative clinical outcome of patients with gastric adenocarcinoma
inferredcites →https://doi.org/10.1056/nejmoa1200690openalex-snapshot
Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
inferredcites →https://doi.org/10.1080/2162402x.2015.1100789openalex-snapshot
Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma
inferredcites →https://doi.org/10.1097/mpa.0b013e3182575e4aopenalex-snapshot
Indoleamine 2,3-dioxygenase Affects the Aggressiveness of Intraductal Papillary Mucinous Neoplasms Through Foxp3+CD4+CD25+ T Cells in Peripheral Blood
inferredcites →https://doi.org/10.1126/science.281.5380.1191openalex-snapshot
Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism
inferredcites →https://doi.org/10.1128/cvi.05402-11openalex-snapshot
Serum Indoleamine 2,3-Dioxygenase Activity Predicts Prognosis of Pulmonary Tuberculosis
inferredcites →https://doi.org/10.1136/gut.2009.185108openalex-snapshot
Gut CD103 + dendritic cells express indoleamine 2,3-dioxygenase which influences T regulatory/T effector cell balance and oral tolerance induction
inferredcites →https://doi.org/10.1186/2051-1426-2-3openalex-snapshot
Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8+ T cells directly within the tumor microenvironment
inferredcites →https://doi.org/10.1200/jco.2011.36.5908openalex-snapshot
Five-Year Outcomes of a Randomized Phase III Trial Comparing Adjuvant Chemotherapy With S-1 Versus Surgery Alone in Stage II or III Gastric Cancer
inferredcites →https://doi.org/10.18632/oncotarget.1916openalex-snapshot
Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation, and cisplatin
inferredcites →https://doi.org/10.18632/oncotarget.8216openalex-snapshot
A phase I study of indoximod in patients with advanced malignancies
inferredcites →https://doi.org/10.3389/fimmu.2014.00521openalex-snapshot
Immunological Relevance of the Coevolution of IDO1 and AHR
inferredcites →https://doi.org/10.4049/jimmunol.0903670openalex-snapshot
An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
inferredcites →https://doi.org/10.4049/jimmunol.1002777openalex-snapshot
IDO and Regulatory T Cell Support Are Critical for Cytotoxic T Lymphocyte-Associated Ag-4 Ig-Mediated Long-Term Solid Organ Allograft Survival

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4772539openalex-extracted
Predicting Immunotherapy Efficacy with Machine Learning in Gastrointestinal Cancers: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1002/jlb.4mr0120-221ropenalex-snapshot
Integrated immune gene expression signature and molecular classification in gastric cancer: New insights
inferred← citeshttps://doi.org/10.1007/16833_2023_182openalex-snapshot
Metabolomics of Gastrointestinal Cancers
inferred← citeshttps://doi.org/10.1016/j.cellin.2026.100330openalex-snapshot
Endogenous metabolite signaling orchestrates tumor immune evasion
inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.173921openalex-snapshot
The footprint of kynurenine pathway in every cancer: a new target for chemotherapy
inferred← citeshttps://doi.org/10.1016/j.intimp.2019.05.009openalex-snapshot
Recent advances in the study of regulatory T cells in gastric cancer
inferred← citeshttps://doi.org/10.1016/j.modpat.2024.100532openalex-snapshot
Expression and Prognostic Significance of LAG-3, TIGIT, VISTA, and IDO1 in Endometrial Serous Carcinoma
inferred← citeshttps://doi.org/10.1016/j.prp.2022.154124openalex-snapshot
Solid-type poorly differentiated adenocarcinoma of the stomach: A characteristic morphology reveals a distinctive immunoregulatory tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.prp.2024.155655openalex-snapshot
IDO1-mediated catabolism of tryptophan in gastric tumors: Its potential role in the axis of histopathology, differentiation and metastasis
inferred← citeshttps://doi.org/10.1016/j.semcancer.2020.07.001openalex-snapshot
News on immune checkpoint inhibitors as immunotherapy strategies in adult and pediatric solid tumors
inferred← citeshttps://doi.org/10.1080/17568919.2026.2741229openalex-snapshot
Heterocyclic scaffolds targeting IDO1: progress in medicinal chemistry and clinical development
inferred← citeshttps://doi.org/10.1097/pai.0000000000000761openalex-snapshot
Expression of Indoleamine 2, 3-dioxygenase 1 (IDO1) and Tryptophanyl-tRNA Synthetase (WARS) in Gastric Cancer Molecular Subtypes
inferred← citeshttps://doi.org/10.1097/pai.0000000000001238openalex-snapshot
IDO1 Expression and CD8+ T-Cell Levels Are Useful Prognostic Biomarkers in Preoperative Gastric Cancer Specimens Before Neoadjuvant Chemotherapy
inferred← citeshttps://doi.org/10.1111/bcp.14316openalex-snapshot
Mechanism‐based treatment of cancer with immune checkpoint inhibitor therapies
inferred← citeshttps://doi.org/10.1126/scisignal.abj4220openalex-snapshot
Metabolite activation of tumorigenic signaling pathways in the tumor microenvironment
inferred← citeshttps://doi.org/10.1177/1756284818815334openalex-snapshot
Role of indoleamine 2,3-dioxygenase in pathology of the gastrointestinal tract
inferred← citeshttps://doi.org/10.1186/s12885-020-06956-5openalex-snapshot
The prognostic value of IDO expression in solid tumors: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1186/s12885-025-15308-0openalex-snapshot
Quercetin inhibits gastric cancer cell proliferation and migration and is associated with the suppression of the IDO1-Kynurenine-AhR axis
inferred← citeshttps://doi.org/10.1371/journal.pone.0259940openalex-snapshot
The role of the immunoescape in colorectal cancer liver metastasis
inferred← citeshttps://doi.org/10.2152/jmi.68.362openalex-snapshot
Impact of CKLF-like MARVEL transmembrane domain containing 6 (CMTM6) expression in gastric cancer
inferred← citeshttps://doi.org/10.2217/imt-2021-0103openalex-snapshot
Immunotherapy for Gastric Cancer: A 2021 Update
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1359914openalex-snapshot
Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors
inferred← citeshttps://doi.org/10.3389/fmicb.2026.1820111openalex-snapshot
The microbiota-tryptophan-brain axis in neurodegenerative diseases: pathogenic mechanisms, disease-specific roles, and translational therapeutics
inferred← citeshttps://doi.org/10.3389/fonc.2022.954495openalex-snapshot
Prognostic role of indoleamine 2,3-dioxygenase 1 expression in solid tumors: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.3389/fonc.2025.1495722openalex-snapshot
Expression of immune checkpoints (IDO and PD-L1) in oral tongue cancer patients: a 10-year retrospective cohort study in Pakistan
inferred← citeshttps://doi.org/10.3389/fphar.2025.1632446openalex-snapshot
IDO and TDO inhibitors in cancer immunotherapy: mechanisms, clinical development, and future directions
inferred← citeshttps://doi.org/10.3390/cancers13112689openalex-snapshot
Expression of Immune Checkpoint Regulators IDO, VISTA, LAG3, and TIM3 in Resected Pancreatic Ductal Adenocarcinoma
inferred← citeshttps://doi.org/10.3390/diagnostics11122370openalex-snapshot
Expression of Immune Checkpoints in Malignant Tumors: Therapy Targets and Biomarkers for the Gastric Cancer Prognosis
inferred← citeshttps://doi.org/10.3390/ijms232213846openalex-snapshot
The Correlation of Ten Immune Checkpoint Gene Expressions and Their Association with Gastric Cancer Development
inferred← citeshttps://doi.org/10.3390/ijms26083706openalex-snapshot
Promising Gastric Cancer Biomarkers—Focus on Tryptophan Metabolism via the Kynurenine Pathway
inferred← citeshttps://doi.org/10.3390/ijms26135937openalex-snapshot
Predicting Immunotherapy Efficacy with Machine Learning in Gastrointestinal Cancers: A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.3892/ijmm.2020.4658openalex-snapshot
Estrogen induces IDO expression via TGF‑β in chorionic villi and decidua during early stages of pregnancy
inferred← citeshttps://doi.org/10.3892/ol.2024.14670openalex-snapshot
T lymphocyte‑related immune response and immunotherapy in gastric cancer (Review)
inferred← citeshttps://doi.org/10.70675/739c9512za8cbz4463z972bz023d80c26b17openalex-snapshot
Screening de molécules antivirales actives sur le virus BK et compréhension du mécanisme d'action
inferred← citeshttps://doi.org/10.7150/jca.31727openalex-snapshot
Role of IDO and TDO in Cancers and Related Diseases and the Therapeutic Implications
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