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Benzoxazole-based Zn(II) and Cu(II) Complexes Overcome Multidrug-resistance in Cancer

https://doi.org/10.21873/anticanres.12971

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Synthesis of Some Novel Benzoxazole Derivatives as Anticancer, Anti‐HIV‐1 and Antimicrobial Agents.

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Efflux Pump Inhibitors: A Strategy to Combat P‐Glycoprotein and the NorA Multidrug Resistance Pump

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Thirty Years of the Drug Candidate NAMI‐A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective

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Structure–activity relationships of novel N-acyloxy-1,4-dihydropyridines as P-glycoprotein inhibitors

inferredcites →https://doi.org/10.1016/j.bmc.2007.11.019openalex-snapshot

Synthesis, metal ion binding, and biological evaluation of new anticancer 2-(2′-hydroxyphenyl)benzoxazole analogs of UK-1

inferredcites →https://doi.org/10.1016/j.bmc.2009.01.072openalex-snapshot

Synthesis and biological evaluation of a small molecule library of 3rd generation multidrug resistance modulators

inferredcites →https://doi.org/10.1016/j.bmc.2017.08.053openalex-snapshot

In vitro antitumor activity of novel benzimidazole-based Cu(II) complexes

inferredcites →https://doi.org/10.1016/j.ejmech.2014.11.064openalex-snapshot

Benzoxazoles and oxazolopyridines in medicinal chemistry studies

inferredcites →https://doi.org/10.1016/j.ejmech.2017.01.044openalex-snapshot

Dregamine and tabernaemontanine derivatives as ABCB1 modulators on resistant cancer cells

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Platinum, palladium, gold and ruthenium complexes as anticancer agents: Current clinical uses, cytotoxicity studies and future perspectives

inferredcites →https://doi.org/10.1016/j.ejmech.2017.07.062openalex-snapshot

Overcoming ABC transporter-mediated multidrug resistance: The dual role of tyrosine kinase inhibitors as multitargeting agents

inferredcites →https://doi.org/10.1016/j.ejmech.2017.12.044openalex-snapshot

Recent advance in oxazole-based medicinal chemistry

inferredcites →https://doi.org/10.1016/j.ejps.2013.09.003openalex-snapshot

The role of a Schiff base scaffold, N-(2-hydroxy acetophenone) glycinate-in overcoming multidrug resistance in cancer

inferredcites →https://doi.org/10.1016/j.jorganchem.2017.03.038openalex-snapshot

Advances in the design of organometallic anticancer complexes

inferredcites →https://doi.org/10.1016/s0968-0896(02)00327-9openalex-snapshot

Synthesis and evaluation of anticancer benzoxazoles and benzimidazoles related to UK-1

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Chemical structure of phenothiazines and their biological activity

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Confocal Imaging to Quantify Passive Transport across Biomimetic Lipid Membranes

inferredcites →https://doi.org/10.1021/acs.jmedchem.7b01689openalex-snapshot

Ru(II) Compounds: Next-Generation Anticancer Metallotherapeutics?

inferredcites →https://doi.org/10.1021/ic400835nopenalex-snapshot

Next-Generation Metal Anticancer Complexes: Multitargeting via Redox Modulation

inferredcites →https://doi.org/10.1021/ic401662dopenalex-snapshot

DNA/Protein Binding, Molecular Docking, and in Vitro Anticancer Activity of Some Thioether-Dipyrrinato Complexes

inferredcites →https://doi.org/10.1021/jm030183aopenalex-snapshot

Multidrug Resistance Reversal Agents

inferredcites →https://doi.org/10.1021/jm070039fopenalex-snapshot

Development of Ruthenium Antitumor Drugs that Overcome Multidrug Resistance Mechanisms

inferredcites →https://doi.org/10.1021/jm900743copenalex-snapshot

Perspectives of P-Glycoprotein Modulating Agents in Oncology and Neurodegenerative Diseases: Pharmaceutical, Biological, and Diagnostic Potentials

inferredcites →https://doi.org/10.1039/c3dt33077jopenalex-snapshot

Zinc(ii) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cells

inferredcites →https://doi.org/10.1039/c5dt03919copenalex-snapshot

Metal-based drugs that break the rules

inferredcites →https://doi.org/10.1080/2164232x.2014.886963openalex-snapshot

Synthesis, characterization and biological profile of metal and azo-metal complexes of embelin

inferredcites →https://doi.org/10.1186/s13065-018-0459-5openalex-snapshot

Benzoxazole derivatives: design, synthesis and biological evaluation

inferredcites →https://doi.org/10.1248/cpb.c18-00158openalex-snapshot

Synthesis and Antimicrobial Activity of 2-Trifluoroacetonylbenzoxazole Ligands and Their Metal Complexes

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How to overcome ATP-binding cassette drug efflux transporter-mediated drug resistance?

inferredcites →https://doi.org/10.2174/138945011795378540openalex-snapshot

Improving Cancer Chemotherapy with Modulators of ABC Drug Transporters

inferredcites →https://doi.org/10.2174/1874-470210801020093openalex-snapshot

Reversal of ABC Drug Transporter-Mediated Multidrug Resistance in Cancer Cells: Evaluation of Current Strategies

inferredcites →https://doi.org/10.3390/molecules20057951openalex-snapshot

Special Issue: Practical Applications of Metal Complexes

inferredcites →https://doi.org/10.3390/molecules23051232openalex-snapshot

Evaluation of Transition Metal Complexes of Benzimidazole-Derived Scaffold as Promising Anticancer Chemotherapeutics

inferredcites →https://doi.org/10.5281/zenodo.1189321openalex-snapshot

Metallo - Bioactive Compounds As Potential Novel Anticancer Therapy

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Synthesis and Anti-Cancer Investigations of Novel Copper(II) Complexes Based on Adenine

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Zn(II) 5,5‐Diethylbarbiturate Complex Selectively Induces Apoptosis in Breast Cancer and Breast Cancer Stem‐Like Cells

inferred← citeshttps://doi.org/10.1002/smll.202107160openalex-snapshot

Intracellular Mutual Amplification of Oxidative Stress and Inhibition Multidrug Resistance for Enhanced Sonodynamic/Chemodynamic/Chemo Therapy

inferred← citeshttps://doi.org/10.1007/s10495-024-02059-9openalex-snapshot

Involvement of copper in cell death and cancer

inferred← citeshttps://doi.org/10.1016/j.apcato.2025.207031openalex-snapshot

Exploring magnetically recoverable catalysts for the synthesis of benzoxazoles derivatives

inferred← citeshttps://doi.org/10.1016/j.jphotochem.2023.114769openalex-snapshot

Insights into the photo- and thermal induced intramolecular processes of 2-(hydroxyphenyl)benzoxazoles: Experimental and theoretical aspects

inferred← citeshttps://doi.org/10.1016/j.mencom.2022.11.018openalex-snapshot

Synthesis, molecular structure and biological activity of Niii complexes based on substituted 2-(2-hydroxyphenyl)benzoxazole

inferred← citeshttps://doi.org/10.1016/j.molstruc.2021.131327openalex-snapshot

Green synthesis, X-ray crystal structure, evaluation as in vitro cytotoxic and antibacterial agents of a new Zn(II) complex containing dipicolinic acid

inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.138836openalex-snapshot

Synthesis and anti-cancer investigations of copper(II) complexes based on adenine

inferred← citeshttps://doi.org/10.1038/s41598-024-63433-wopenalex-snapshot

Cuproptosis-related lncRNA signature as a prognostic tool and therapeutic target in diffuse large B cell lymphoma

inferred← citeshttps://doi.org/10.1039/d0dt03566aopenalex-snapshot

Cu( i ) complexes as new antiproliferative agents against sensitive and doxorubicin resistant colorectal cancer cells: synthesis, characterization, and mechanisms of action

inferred← citeshttps://doi.org/10.1039/d0qi01344gopenalex-snapshot

Unprecedented collateral sensitivity for cisplatin-resistant lung cancer cells presented by new ruthenium organometallic compounds

inferred← citeshttps://doi.org/10.1186/s43094-020-00115-0openalex-snapshot

Anticancer activity of benzoxazole derivative (2015 onwards): a review

inferred← citeshttps://doi.org/10.1186/s43094-021-00252-0openalex-snapshot

Synthesis, characterization, and pharmacological evaluation of some metal complexes of quercetin as P-gp inhibitors

inferred← citeshttps://doi.org/10.21873/anticanres.13864openalex-snapshot

New Chalcone Derivative Inhibits ABCB1 in Multidrug Resistant T-cell Lymphoma and Colon Adenocarcinoma Cells

inferred← citeshttps://doi.org/10.3389/fonc.2022.1020566openalex-snapshot

Development and validation of a cuproptosis-associated prognostic model for diffuse large B-cell lymphoma

inferred← citeshttps://doi.org/10.3390/antibiotics9100649openalex-snapshot

Benzoxazole-Based Metal Complexes to Reverse Multidrug Resistance in Bacteria

inferred← citeshttps://doi.org/10.3390/ph13120453openalex-snapshot

Antimicrobial, Anticancer and Multidrug-Resistant Reversing Activity of Novel Oxygen-, Sulfur- and Selenoflavones and Bioisosteric Analogues

inferred← citeshttps://doi.org/10.58567/ci02010003openalex-snapshot

Repurposing anti-parasite benzimidazole drugs as selective anti-cancer chemotherapeutics

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