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Mathematical modelling of drug delivery to solid tumour
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Outgoing claims: the papers this work cites, builds on, or argues with.
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Morphometric analyses of the microvasculature of tumors during growth and after x-irradiation
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Differential macromolecular leakage from the vasculature of tumors
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Decreased cardiac toxicity of doxorubicin administered by continuous intravenous infusion in combination chemotherapy for metastatic breast carcinoma
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Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer
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Tissue distribution and therapeutic effect of intravenous free or encapsulated liposomal doxorubicin on human prostate carcinoma xenografts
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Hindered transport of large molecules in liquid‐filled pores
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Microscopic observations on the growth of blood capillaries in the living mammal
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Flow cytometric assessment of the cellular pharmacokinetics of fluorescent drugs
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MRIgHIFU: A tool for image‐guided therapeutics
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Three‐dimensional spatial and temporal temperature control with MR thermometry‐guided focused ultrasound (MRgHIFU)
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Measurement of Material Extravasation in Microvascular Networks Using Fluorescence Video-Microscopy
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Transport of molecules across tumor vasculature
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Cell killing action of cell cycle phase-non-specific antitumor agents is dependent on concentration-time product
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Microvascular structure of benign and malignant tumors of the colon in humans
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Poroviscoelastic Modeling of Liver Biomechanical Response in Unconfined Compression
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P-Glycoprotein Induction and Tumor Cell-Kill Dynamics in Response to Differential Doxorubicin Dosing Strategies: A Theoretical Pharmacodynamic Model
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Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes
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Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes
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Comparative intracellular uptake of adriamycin and 4'-deoxydoxorubicin by nonsmall cell lung tumor cells in culture and its relationship to cell survival
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Drugs released from polymers: diffusion and elimination in brain tissue
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Microvascular permeability of normal and neoplastic tissues
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Transport of fluid and macromolecules in tumors. I. Role of interstitial pressure and convection
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Transport of fluid and macromolecules in tumors. II. Role of heterogeneous perfusion and lymphatics
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Transport of fluid and macromolecules in tumors
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Transport of fluid and macromolecules in tumors. IV. A microscopic model of the perivascular distribution
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Pharmacokinetics of adriamycin in patients with breast cancer: Correlation between pharmacokinetic parameters and clinical short-term response
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Principles and models of biological transport
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A mathematical model of Doxorubicin treatment efficacy for non-Hodgkin?s lymphoma: investigation of the current protocol through theoretical modelling results
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Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation
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Transient interstitial fluid flow in brain tumors: Effect on drug delivery
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On an acoustics–thermal–fluid coupling model for the prediction of temperature elevation in liver tumor
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Simulation study on acoustic streaming and convective cooling in blood vessels during a high-intensity focused ultrasound thermal ablation
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Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus
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Magnetic resonance imaging of high intensity focused ultrasound mediated drug delivery from temperature-sensitive liposomes: An in vivo proof-of-concept study
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Optimization of a novel and improved thermosensitive liposome formulated with DPPC and a Brij surfactant using a robust in vitro system
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Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model
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A thermosensitive liposome prepared with a Cu2+ gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy
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Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound
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Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood–tumor and blood–brain barriers improve outcomes in a rat glioma model
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Effect of heterogeneous vasculature on interstitial transport within a solid tumor
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[186Re]Liposomal doxorubicin (Doxil): in vitro stability, pharmacokinetics, imaging and biodistribution in a head and neck squamous cell carcinoma xenograft model
inferredcites →https://doi.org/10.1016/s0006-2952(98)00307-4openalex-snapshot
A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
inferredcites →https://doi.org/10.1016/s0009-2509(98)00173-0openalex-snapshot
Three-dimensional simulation of IgG delivery to tumors
inferredcites →https://doi.org/10.1016/s0009-9260(66)80027-2openalex-snapshot
Microcirculation of tumors Part I: Anatomy, function, and necrosis
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Inhibition of the P-glycoprotein- and multidrug resistance protein-mediated efflux of anthracyclines and calceinacetoxymethyl ester by PAK-104P
inferredcites →https://doi.org/10.1016/s0021-9673(01)85930-6openalex-snapshot
Molecular weight distribution analysis by gel chromatography on sephadex
inferredcites →https://doi.org/10.1016/s0022-2836(64)80115-7openalex-snapshot
Negative staining of phospholipids and their structural modification by surface-active agents as observed in the electron microscope
inferredcites →https://doi.org/10.1016/s0022-2836(65)80093-6openalex-snapshot
Diffusion of univalent ions across the lamellae of swollen phospholipids
inferredcites →https://doi.org/10.1016/s0026-2862(82)80002-2openalex-snapshot
Vascular permeability to macromolecules in rabbit paw and skeletal muscle: A lymphatic study with a mathematical interpretation of transport processes
inferredcites →https://doi.org/10.1016/s0168-3659(01)00308-xopenalex-snapshot
Determinants of drug delivery and transport to solid tumors
inferredcites →https://doi.org/10.1016/s0168-3659(03)00240-2openalex-snapshot
Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin
inferredcites →https://doi.org/10.1016/s0168-3659(99)00248-5openalex-snapshot
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
inferredcites →https://doi.org/10.1016/s0304-4165(03)00139-9openalex-snapshot
Simulation model of doxorubicin activity in islets of human breast cancer cells
inferredcites →https://doi.org/10.1016/s0360-3016(96)00389-6openalex-snapshot
Thermosensitive liposomes: Extravasation and release of contents in tumor microvascular networks
inferredcites →https://doi.org/10.1016/s0959-8049(97)00114-7openalex-snapshot
Influence of drug exposure parameters on the activity of paclitaxel in multicellular spheroids
inferredcites →https://doi.org/10.1016/s1476-5586(03)80008-8openalex-snapshot
A Mathematical Model for Cisplatin Cellular Pharmacodynamics
inferredcites →https://doi.org/10.1023/a:1011076110317openalex-snapshot
Simulation of the Delivery of Doxorubicin to Hepatoma
inferredcites →https://doi.org/10.1023/a:1016206631006openalex-snapshot
Thermosensitive Sterically Stabilized Liposomes: Formulation and in Vitro Studies on Mechanism of Doxorubicin Release by Bovine Serum and Human Plasma
inferredcites →https://doi.org/10.1023/a:1018949218380openalex-snapshot
Enhanced Delivery and Antitumor Activity of Doxorubicin Using Long-Circulating Thermosensitive Liposomes Containing Amphipathic Polyethylene Glycol in Combination with Local Hyperthermia
inferredcites →https://doi.org/10.1023/a:1025785505977openalex-snapshot
Drug Delivery and Transport to Solid Tumors
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Dependence of the cytostatic effect of adriamycin on drug concentration and exposure time in vitro
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Imaging of angiogenesis: from microscope to clinic
inferredcites →https://doi.org/10.1038/nrc1591openalex-snapshot
High-intensity focused ultrasound in the treatment of solid tumours
inferredcites →https://doi.org/10.1038/sj.neo.7900096openalex-snapshot
A Mathematical Model for Comparison of Bolus Injection, Continuous Infusion, and Liposomal Delivery of Doxorubicin to Tumor Cells
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Investigating the effects of ABC transporter-based acquired drug resistance mechanisms at the cellular and tissue scale
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Differential effects of mitomycin C and doxorubicin on P-glycoprotein expression
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Use of Plasma Pharmacokinetics to Predict and Prevent Methotrexate Toxicity
inferredcites →https://doi.org/10.1056/nejm199809243391307openalex-snapshot
Doxorubicin-Induced Cardiomyopathy
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Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment
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Mosaic blood vessels in tumors: Frequency of cancer cells in contact with flowing blood
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Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy
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Open junctions in the endothelium of the postcapillary venules of the diaphragm.
inferredcites →https://doi.org/10.1085/jgp.78.4.349openalex-snapshot
A Fickian diffusion transport process with features of transport catalysis. Doxorubicin transport in human red blood cells.
inferredcites →https://doi.org/10.1093/jnci/53.5.1229openalex-snapshot
Quantitative Studies on the Developing Vascular System of Rat Hepatoma2
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Tissue Perfusion Inhomogeneity During Early Tumor Growth in Rats 2
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Microcirculatory Studies in Rat Mammary Carcinoma. I. Transparent Chamber Method, Development of Microvasculature, and Pressures in Tumor Vessels 2 3
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Tumor Vascular Permeability, Accumulation, and Penetration of Macromolecular Drug Carriers
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TP53 Mutational Status and Cetuximab Benefit in Rectal Cancer: 5-Year Results of the EXPERT-C Trial
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Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy
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Numerical simulations of heating patterns and tissue temperature response due to high-intensity focused ultrasound
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Improved Volumetric MR-HIFU Ablation by Robust Binary Feedback Control
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Ultrasound stimulated release of liposomal calcein
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Characterization of Heterogeneous Distribution of Tumor Blood Flow in the Rat
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KINETICS OF WOUND HEALING IN RABBIT EAR CHAMBERS, A TIME LAPSE CINEMICROSCOPIC STUDY
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Effects of variation in perfusion rates and of perfusion models in computational models of radio frequency tumor ablation
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Volumetric HIFU ablation under 3D guidance of rapid MRI thermometry
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Effects of different parameters in the fast scanning method for HIFU treatment
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Theoretical and experimental evaluation of a temperature controller for scanned focused ultrasound hyperthermia
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Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model
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Effect of acoustic nonlinearity on heating of biological tissue by high-intensity focused ultrasound
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Physical mechanisms of the therapeutic effect of ultrasound (a review)
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Permeability of single capillaries to intermediate-sized colored solutes
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Integral-mass balance method for determination of solvent drag reflection coefficient
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Filtration, Diffusion and Molecular Sieving Through Peripheral Capillary Membranes
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Regulation of vascular endothelial barrier function
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Cisplatin induces renal expression of P-glycoprotein and canalicular multispecific organic anion transporter
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Analysis of Tissue and Arterial Blood Temperatures in the Resting Human Forearm
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Interstitial-lymphatic mechanisms in the control of extracellular fluid volume
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Determination and Modeling of Kinetics of Cancer Cell Killing by Doxorubicin and Doxorubicin Encapsulated in Targeted Liposomes
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Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors
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Mosaic Tumor Vessels: Cellular Basis and Ultrastructure of Focal Regions Lacking Endothelial Cell Markers
inferredcites →https://doi.org/10.1158/1078-0432.826.11.2openalex-snapshot
Mathematical Modeling and Optimization of Drug Delivery from Intratumorally Injected Microspheres
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Novel Temperature-Sensitive Liposomes with Prolonged Circulation Time
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The Distribution of the Anticancer Drug Doxorubicin in Relation to Blood Vessels in Solid Tumors
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Basic Principles of Pharmacokinetics
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A tumor cord model for Doxorubicin delivery and dose optimization in solid tumors
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Doxorubicin clearance in the obese.
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Dose-Finding and Pharmacokinetic Study of Cisplatin, Gemcitabine, and SU5416 in Patients With Solid Tumors
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Reduced Cardiotoxicity and Preserved Antitumor Efficacy of Liposome-Encapsulated Doxorubicin and Cyclophosphamide Compared With Conventional Doxorubicin and Cyclophosphamide in a Randomized, Multicenter Trial of Metastatic Breast Cancer
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Long-Term Survival Results of a Randomized Trial Comparing Gemcitabine Plus Cisplatin, With Methotrexate, Vinblastine, Doxorubicin, Plus Cisplatin in Patients With Bladder Cancer
inferredcites →https://doi.org/10.2165/00003088-200342050-00002openalex-snapshot
Pharmacokinetics of Pegylated Liposomal Doxorubicin
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The design and application of upwind schemes on unstructured meshes
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Localised drug release using MRI-controlled focused ultrasound hyperthermia
inferredcites →https://doi.org/10.3109/02656736.2012.677930openalex-snapshot
Targeted drug delivery by high intensity focused ultrasound mediated hyperthermia combined with temperature-sensitive liposomes: Computational modelling and preliminary in vivovalidation
inferredcites →https://doi.org/10.3109/02656736.2012.736670openalex-snapshot
Enhanced drug delivery in rabbit VX2 tumours using thermosensitive liposomes and MRI-controlled focused ultrasound hyperthermia
inferredcites →https://doi.org/10.3109/08982104.2013.779702openalex-snapshot
Towards an understanding of the release behavior of temperature-sensitive liposomes: a possible explanation of the “pseudoequilibrium” release behavior at the phase transition temperature
inferredcites →https://doi.org/10.3109/10739689709148315openalex-snapshot
Geometric Resistance and Microvascular Network Architecture of Human Colorectal Carcinoma
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Reduction of Doxorubicin Cardiotoxicity by Prolonged Continuous Intravenous Infusion
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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