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Genetic control of de novo lipogenesis: role in diet-induced obesity

https://doi.org/10.3109/10409231003667500

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Scd3—A Novel Gene of the Stearoyl-CoA Desaturase Family with Restricted Expression in Skin

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Inducible Gene Targeting in Mice Using the Cre/loxSystem

inferredcites →https://doi.org/10.1007/s00109-009-0449-0openalex-snapshot

Elovl6: a new player in fatty acid metabolism and insulin sensitivity

inferredcites →https://doi.org/10.1016/j.bbrc.2005.12.029openalex-snapshot

Glucose activation of ChREBP in hepatocytes occurs via a two-step mechanism

inferredcites →https://doi.org/10.1016/j.bbrc.2008.01.075openalex-snapshot

Mouse Elovl-6 promoter is an SREBP target

inferredcites →https://doi.org/10.1016/j.cell.2004.11.043openalex-snapshot

Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP

inferredcites →https://doi.org/10.1016/j.cell.2005.12.022openalex-snapshot

Protein Sensors for Membrane Sterols

inferredcites →https://doi.org/10.1016/j.cell.2008.07.048openalex-snapshot

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

inferredcites →https://doi.org/10.1016/j.cell.2009.05.036openalex-snapshot

Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

inferredcites →https://doi.org/10.1016/j.cmet.2004.12.008openalex-snapshot

Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes

inferredcites →https://doi.org/10.1016/j.cmet.2005.04.002openalex-snapshot

“New” hepatic fat activates PPARα to maintain glucose, lipid, and cholesterol homeostasis

inferredcites →https://doi.org/10.1016/j.cmet.2005.05.004openalex-snapshot

Metabolic control through the PGC-1 family of transcription coactivators

inferredcites →https://doi.org/10.1016/j.cmet.2005.06.006openalex-snapshot

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

inferredcites →https://doi.org/10.1016/j.cmet.2007.10.014openalex-snapshot

Hepatic Stearoyl-CoA Desaturase-1 Deficiency Protects Mice from Carbohydrate-Induced Adiposity and Hepatic Steatosis

inferredcites →https://doi.org/10.1016/j.cmet.2009.01.002openalex-snapshot

Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy

inferredcites →https://doi.org/10.1016/j.cmet.2009.01.011openalex-snapshot

The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator-1 β in the Pathogenesis of Fructose-Induced Insulin Resistance

inferredcites →https://doi.org/10.1016/s0021-9258(17)34693-8openalex-snapshot

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

inferredcites →https://doi.org/10.1016/s0021-9258(19)85167-0openalex-snapshot

Exploration of a liver-specific, glucose/insulin-responsive promoter in transgenic mice

inferredcites →https://doi.org/10.1016/s0022-2275(20)30465-xopenalex-snapshot

Cloning and characterization of a mammalian fatty acyl-CoA elongase as a lipogenic enzyme regulated by SREBPs

inferredcites →https://doi.org/10.1016/s1097-2765(05)00010-9openalex-snapshot

Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice

inferredcites →https://doi.org/10.1038/15446openalex-snapshot

Scd1 is expressed in sebaceous glands and is disrupted in the asebia mouse

inferredcites →https://doi.org/10.1038/383728a0openalex-snapshot

An oxysterol signalling pathway mediated by the nuclear receptor LXRα

inferredcites →https://doi.org/10.1038/75651openalex-snapshot

Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat

inferredcites →https://doi.org/10.1038/nature05485openalex-snapshot

Inflammation and metabolic disorders

inferredcites →https://doi.org/10.1038/nature08532openalex-snapshot

Human genetics illuminates the paths to metabolic disease

inferredcites →https://doi.org/10.1038/nbt915openalex-snapshot

Approaches for the sequence-specific knockdown of mRNA

inferredcites →https://doi.org/10.1038/nm1662openalex-snapshot

Crucial role of a long-chain fatty acid elongase, Elovl6, in obesity-induced insulin resistance

inferredcites →https://doi.org/10.1038/nrd1469openalex-snapshot

Lipid metabolic enzymes: emerging drug targets for the treatment of obesity

inferredcites →https://doi.org/10.1038/nrg2468openalex-snapshot

Metabolic syndrome: from epidemiology to systems biology

inferredcites →https://doi.org/10.1038/oby.2008.528openalex-snapshot

Gene–Environment Interactions in the Etiology of Obesity: Defining the Fundamentals

inferredcites →https://doi.org/10.1042/bst0340223openalex-snapshot

Regulation of acetyl-CoA carboxylase

inferredcites →https://doi.org/10.1073/pnas.0401516101openalex-snapshot

Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

inferredcites →https://doi.org/10.1073/pnas.0401627101openalex-snapshot

Stearoyl-CoA desaturase 1 deficiency increases fatty acid oxidation by activating AMP-activated protein kinase in liver

inferredcites →https://doi.org/10.1073/pnas.0404297101openalex-snapshot

Central role for liver X receptor in insulin-mediated activation of Srebp-1c transcription and stimulation of fatty acid synthesis in liver

inferredcites →https://doi.org/10.1073/pnas.0409451102openalex-snapshot

Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice

inferredcites →https://doi.org/10.1073/pnas.0505714102openalex-snapshot

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

inferredcites →https://doi.org/10.1073/pnas.0603115103openalex-snapshot

Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis

inferredcites →https://doi.org/10.1073/pnas.0706794104openalex-snapshot

Continuous fat oxidation in acetyl–CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

inferredcites →https://doi.org/10.1073/pnas.0909055106openalex-snapshot

aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues

inferredcites →https://doi.org/10.1073/pnas.0931394100openalex-snapshot

Fatty acid synthesis is essential in embryonic development: Fatty acid synthase null mutants and most of the heterozygotes die in utero

inferredcites →https://doi.org/10.1073/pnas.132384699openalex-snapshot

Loss of stearoyl–CoA desaturase-1 function protects mice against adiposity

inferredcites →https://doi.org/10.1073/pnas.1534923100openalex-snapshot

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

inferredcites →https://doi.org/10.1073/pnas.161284298openalex-snapshot

A glucose-responsive transcription factor that regulates carbohydrate metabolism in the liver

inferredcites →https://doi.org/10.1073/pnas.1733877100openalex-snapshot

Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets

inferredcites →https://doi.org/10.1073/pnas.91.23.10809openalex-snapshot

Ubiquitous receptor: a receptor that modulates gene activation by retinoic acid and thyroid hormone receptors.

inferredcites →https://doi.org/10.1073/pnas.95.11.5987openalex-snapshot

Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice

inferredcites →https://doi.org/10.1073/pnas.96.22.12737openalex-snapshot

Sterol regulatory element binding protein-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis-related genes

inferredcites →https://doi.org/10.1073/pnas.96.24.13656openalex-snapshot

Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes

inferredcites →https://doi.org/10.1073/pnas.97.4.1444openalex-snapshot

The subcellular localization of acetyl-CoA carboxylase 2

inferredcites →https://doi.org/10.1074/jbc.271.10.5321openalex-snapshot

Transcriptional Glucose Signaling through The Glucose Response Element Is Mediated by the Pentose Phosphate Pathway

inferredcites →https://doi.org/10.1074/jbc.273.40.25537openalex-snapshot

Polyunsaturated Fatty Acids Decrease Expression of Promoters with Sterol Regulatory Elements by Decreasing Levels of Mature Sterol Regulatory Element-binding Protein

inferredcites →https://doi.org/10.1074/jbc.273.52.35299openalex-snapshot

Nuclear Sterol Regulatory Element-binding Proteins Activate Genes Responsible for the Entire Program of Unsaturated Fatty Acid Biosynthesis in Transgenic Mouse Liver

inferredcites →https://doi.org/10.1074/jbc.274.33.23577openalex-snapshot

Sterol Regulatory Element Binding Protein-1 Expression Is Suppressed by Dietary Polyunsaturated Fatty Acids

inferredcites →https://doi.org/10.1074/jbc.274.36.25892openalex-snapshot

Fish Oil Feeding Decreases Mature Sterol Regulatory Element-binding Protein 1 (SREBP-1) by Down-regulation of SREBP-1c mRNA in Mouse Liver

inferredcites →https://doi.org/10.1074/jbc.274.50.35832openalex-snapshot

Sterol Regulatory Element-binding Protein-1 as a Key Transcription Factor for Nutritional Induction of Lipogenic Enzyme Genes

inferredcites →https://doi.org/10.1074/jbc.m007273200openalex-snapshot

Unsaturated Fatty Acids Down-regulate SREBP Isoforms 1a and 1c by Two Mechanisms in HEK-293 Cells

inferredcites →https://doi.org/10.1074/jbc.m108413200openalex-snapshot

Identification of a Mammalian Long Chain Fatty Acyl Elongase Regulated by Sterol Regulatory Element-binding Proteins

inferredcites →https://doi.org/10.1074/jbc.m109.014225openalex-snapshot

Skin-specific Deletion of Stearoyl-CoA Desaturase-1 Alters Skin Lipid Composition and Protects Mice from High Fat Diet-induced Obesity

inferredcites →https://doi.org/10.1074/jbc.m111041200openalex-snapshot

Direct and Indirect Mechanisms for Regulation of Fatty Acid Synthase Gene Expression by Liver X Receptors

inferredcites →https://doi.org/10.1074/jbc.m310512200openalex-snapshot

ATP-Citrate Lyase Deficiency in the Mouse

inferredcites →https://doi.org/10.1074/jbc.m311000200openalex-snapshot

Lipopenia and Skin Barrier Abnormalities in DGAT2-deficient Mice

inferredcites →https://doi.org/10.1074/jbc.m311301200openalex-snapshot

Mlx Is the Functional Heteromeric Partner of the Carbohydrate Response Element-binding Protein in Glucose Regulation of Lipogenic Enzyme Genes

inferredcites →https://doi.org/10.1074/jbc.m402781200openalex-snapshot

Stearoyl-CoA Desaturase 1 Gene Expression Is Necessary for Fructose-mediated Induction of Lipogenic Gene Expression by Sterol Regulatory Element-binding Protein-1c-dependent and -independent Mechanisms

inferredcites →https://doi.org/10.1074/jbc.m503181200openalex-snapshot

Mitochondrial Glycerol-3-phosphate Acyltransferase-1 Is Essential inLiver for the Metabolism of ExcessAcyl-CoAs

inferredcites →https://doi.org/10.1074/jbc.m605023200openalex-snapshot

The Liver X Receptor (LXR) and Hepatic Lipogenesis

inferredcites →https://doi.org/10.1074/jbc.m610158200openalex-snapshot

Stearoyl-CoA Desaturase-1 Mediates the Pro-lipogenic Effects of Dietary Saturated Fat

inferredcites →https://doi.org/10.1074/jbc.m806108200openalex-snapshot

Unsaturated Fatty Acids Inhibit Proteasomal Degradation of Insig-1 at a Postubiquitination Step

inferredcites →https://doi.org/10.1074/jbc.m807503200openalex-snapshot

Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin

inferredcites →https://doi.org/10.1093/jn/128.6.923openalex-snapshot

Polyunsaturated Fatty Acid Regulation of Gene Expression

inferredcites →https://doi.org/10.1093/jn/131.9.2260openalex-snapshot

Targeted Disruption of Stearoyl-CoA Desaturase1 Gene in Mice Causes Atrophy of Sebaceous and Meibomian Glands and Depletion of Wax Esters in the Eyelid

inferredcites →https://doi.org/10.1093/jn/132.11.3333openalex-snapshot

Dietary Polyunsaturated Fats Regulate Rat Liver Sterol Regulatory Element Binding Proteins-1 and -2 in Three Distinct Stages and by Different Mechanisms

inferredcites →https://doi.org/10.1093/nar/20.8.1871openalex-snapshot

Cis-regulation of the L-type pyruvate kinase gene promoter by glucose, insulin and cyclic AMP

inferredcites →https://doi.org/10.1101/gad.844900openalex-snapshot

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ

inferredcites →https://doi.org/10.1101/gad.9.9.1033openalex-snapshot

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

inferredcites →https://doi.org/10.1111/j.1432-1033.1983.tb07751.xopenalex-snapshot

Carnitine palmitoyltransferase I

inferredcites →https://doi.org/10.1111/j.1467-789x.2006.00220.xopenalex-snapshot

Obesity drugs and their targets: correlation of mouse knockout phenotypes with drug effects in vivo

inferredcites →https://doi.org/10.1111/j.1753-4887.2004.tb00046.xopenalex-snapshot

Methods in Nutrition Science: Cre/loxP System for Generating Tissue-specific Knockout Mouse Models

inferredcites →https://doi.org/10.1111/j.1753-4887.2004.tb00058.xopenalex-snapshot

Polyunsaturated Fatty Acid Regulation of Gene Expression

inferredcites →https://doi.org/10.1111/j.1753-4887.2008.00128.xopenalex-snapshot

Gene-environment interaction and obesity

inferredcites →https://doi.org/10.1124/mol.62.6.1299openalex-snapshot

Novel Roles of Liver X Receptors Exposed by Gene Expression Profiling in Liver and Adipose Tissue

inferredcites →https://doi.org/10.1126/science.1056843openalex-snapshot

Continuous Fatty Acid Oxidation and Reduced Fat Storage in Mice Lacking Acetyl-CoA Carboxylase 2

inferredcites →https://doi.org/10.1126/science.288.5475.2379openalex-snapshot

Reduced Food Intake and Body Weight in Mice Treated with Fatty Acid Synthase Inhibitors

inferredcites →https://doi.org/10.1126/science.294.5548.1866openalex-snapshot

Nuclear Receptors and Lipid Physiology: Opening the X-Files

inferredcites →https://doi.org/10.1128/mcb.01122-06openalex-snapshot

Hepatic De Novo Lipogenesis Is Present in Liver-Specific ACC1-Deficient Mice

inferredcites →https://doi.org/10.1128/mcb.21.22.7558-7568.2001openalex-snapshot

Autoregulation of the Human Liver X Receptor α Promoter

inferredcites →https://doi.org/10.1128/mcb.22.23.8204-8214.2002openalex-snapshot

Mitochondrial Glycerol-3-Phosphate Acyltransferase-Deficient Mice Have Reduced Weight and Liver Triacylglycerol Content and Altered Glycerolipid Fatty Acid Composition

inferredcites →https://doi.org/10.1146/annurev-nutr-080508-141200openalex-snapshot

Management of the Metabolic Syndrome and Type 2 Diabetes Through Lifestyle Modification

inferredcites →https://doi.org/10.1146/annurev.biochem.73.011303.074027openalex-snapshot

MONITORING ENERGY BALANCE: Metabolites of Fatty Acid Synthesis as Hypothalamic Sensors

inferredcites →https://doi.org/10.1146/annurev.biochem.75.103004.142512openalex-snapshot

Obesity-Related Derangements in Metabolic Regulation

inferredcites →https://doi.org/10.1146/annurev.nutr.17.1.77openalex-snapshot

REGULATION OF MAMMALIAN ACETYL-COENZYME A CARBOXYLASE

inferredcites →https://doi.org/10.1146/annurev.nutr.25.050304.092532openalex-snapshot

Control of Energy Homeostasis: Role of Enzymes and Intermediates of Fatty Acid Metabolism in the Central Nervous System

inferredcites →https://doi.org/10.1146/annurev.nutr.27.061406.093618openalex-snapshot

ChREBP, a Transcriptional Regulator of Glucose and Lipid Metabolism

inferredcites →https://doi.org/10.1146/annurev.nutr.28.061807.155434openalex-snapshot

Malonyl-CoA, a Key Signaling Molecule in Mammalian Cells

inferredcites →https://doi.org/10.1172/jci0213880openalex-snapshot

Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands

inferredcites →https://doi.org/10.1172/jci0215593openalex-snapshot

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

inferredcites →https://doi.org/10.1172/jci118645openalex-snapshot

Human fatty acid synthesis is stimulated by a eucaloric low fat, high carbohydrate diet.

inferredcites →https://doi.org/10.1172/jci119247openalex-snapshot

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells.

inferredcites →https://doi.org/10.1172/jci13880openalex-snapshot

Leptin modulates the effects of acyl CoA:diacylglycerol acyltransferase deficiency on murine fur and sebaceous glands

inferredcites →https://doi.org/10.1172/jci15593openalex-snapshot

SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

inferredcites →https://doi.org/10.1172/jci200523962openalex-snapshot

Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1

inferredcites →https://doi.org/10.1172/jci23962openalex-snapshot

Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase–1

inferredcites →https://doi.org/10.1172/jci25256openalex-snapshot

Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation

inferredcites →https://doi.org/10.1172/jci26991openalex-snapshot

Critical role of stearoyl-CoA desaturase-1 (SCD1) in the onset of diet-induced hepatic insulin resistance

inferredcites →https://doi.org/10.1172/jci27300openalex-snapshot

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2

inferredcites →https://doi.org/10.1172/jci2961openalex-snapshot

Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.

inferredcites →https://doi.org/10.1172/jci31183openalex-snapshot

Brain fatty acid synthase activates PPARα to maintain energy homeostasis

inferredcites →https://doi.org/10.1172/jci34275openalex-snapshot

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

inferredcites →https://doi.org/10.1172/jci34314openalex-snapshot

ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver

inferredcites →https://doi.org/10.1172/jci6223openalex-snapshot

Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting

inferredcites →https://doi.org/10.1194/jlr.m500553-jlr200openalex-snapshot

Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity

inferredcites →https://doi.org/10.1194/jlr.m700592-jlr200openalex-snapshot

Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6−/− mice

inferredcites →https://doi.org/10.1194/jlr.m800379-jlr200openalex-snapshot

Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation

inferredcites →https://doi.org/10.1194/jlr.r800079-jlr200openalex-snapshot

Fatty acid metabolism: target for metabolic syndrome

inferredcites →https://doi.org/10.1210/jc.2005-1709openalex-snapshot

Contributions of Different Fatty Acid Sources to Very Low-Density Lipoprotein-Triacylglycerol in the Fasted and Fed States

inferredcites →https://doi.org/10.1210/me.14.5.741openalex-snapshot

Cross-Talk between Fatty Acid and Cholesterol Metabolism Mediated by Liver X Receptor-

inferredcites →https://doi.org/10.1301/nr2004.jun243-246openalex-snapshot

Cre/loxP System for Generating Tissue-specific Knockout Mouse Models

inferredcites →https://doi.org/10.2337/diabetes.53.2007.s36openalex-snapshot

Putative Metabolic Effects of the Liver X Receptor (LXR)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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High total water loss driven by low-fat diet in desert-adapted mice

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The Long Non‐Coding RNA Obesity‐Related (Obr) Contributes To Lipid Metabolism Through Epigenetic Regulation

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Silymarin and Its Isolated Flavanonol Lignans Are Liver X Receptor Antagonists

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Triglyceride Metabolism in the Liver

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Contribution of Adipose Tissue Inflammation to the Development of Type 2 Diabetes Mellitus

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Alleviative effect of Ruellia tuberosa L. on NAFLD and hepatic lipid accumulation via modulating hepatic de novo lipogenesis in high‐fat diet plus streptozotocin‐induced diabetic rats

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Inhibition of Adenosine Monophosphate–Activated Protein Kinase–3‐Hydroxy‐3‐Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance

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Transmembrane channel activity in human hepatocytes and cholangiocytes derived from induced pluripotent stem cells

inferred← citeshttps://doi.org/10.1002/j.2040-4603.2018.tb00008.xopenalex-snapshot

Triglyceride Metabolism in the Liver

inferred← citeshttps://doi.org/10.1002/j.2040-4603.2019.tb00055.xopenalex-snapshot

Contribution of Adipose Tissue Inflammation to the Development of Type 2 Diabetes Mellitus

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Parenteral nutrition emulsion inhibits CYP3A4 in an iPSC derived liver organoids testing platform

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Carnosic acid attenuates obesity‐induced glucose intolerance and hepatic fat accumulation by modulating genes of lipid metabolism in C57BL / 6J ‐ob/ob mice

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Sesamol ameliorates diet‐induced obesity in C57BL/6J mice and suppresses adipogenesis in 3T3‐L1 cells via regulating mitochondria‐lipid metabolism

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Diallyl Trisulfide Prevents Obesity and Decreases miRNA‐335 Expression in Adipose Tissue in a Diet‐Induced Obesity Rat Model

inferred← citeshttps://doi.org/10.1002/path.5150openalex-snapshot

Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney

inferred← citeshttps://doi.org/10.1002/ptr.7584openalex-snapshot

Hypolipogenic effects of Icariside E4 via phosphorylation of AMPK and inhibition of MID1IP1 in HepG2 cells

inferred← citeshttps://doi.org/10.1002/wrna.1295openalex-snapshot

‘Micro‐managers’ of hepatic lipid metabolism and NAFLD

inferred← citeshttps://doi.org/10.1007/978-3-319-25065-6_1openalex-snapshot

Transcriptional Regulation of De Novo Lipogenesis in Liver

inferred← citeshttps://doi.org/10.1007/978-3-319-25065-6_12openalex-snapshot

Monounsaturated Fatty Acid Mediated Liver-Adipose Tissue Crosstalk and Metabolic Regulation

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Adipose Tissue DNL and Its Role in Metabolic Homeostasis

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Role of Lipogenesis and Lipid Desaturases in Non-alcoholic Fatty Liver Disease

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Xylitol: One Name, Numerous Benefits

inferred← citeshttps://doi.org/10.1007/978-3-319-27027-2_33openalex-snapshot

Xylitol: One Name, Numerous Benefits

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Genetic deletion of Wdr13 improves the metabolic phenotype of Lepr db/db mice by modulating AP1 and PPARγ target genes

inferred← citeshttps://doi.org/10.1007/s00125-022-05790-7openalex-snapshot

Serum sex hormone-binding globulin is a mediator of the association between intrahepatic lipid content and type 2 diabetes: the Maastricht Study

inferred← citeshttps://doi.org/10.1007/s00210-025-04069-zopenalex-snapshot

The current findings on the gut-liver axis and the molecular basis of NAFLD/NASH associated with gut microbiome dysbiosis

inferred← citeshttps://doi.org/10.1007/s00394-013-0538-2openalex-snapshot

Adipose tissue remodeling in rats exhibiting fructose-induced obesity

inferred← citeshttps://doi.org/10.1007/s00394-013-0613-8openalex-snapshot

Differential effects of high-carbohydrate and high-fat diets on hepatic lipogenesis in rats

inferred← citeshttps://doi.org/10.1007/s00441-018-2812-3openalex-snapshot

Fatty acids promote bovine skeletal muscle satellite cell differentiation by regulating ELOVL3 expression

inferred← citeshttps://doi.org/10.1007/s10068-024-01741-7openalex-snapshot

Effect of onion peel extract and quercetin at an equivalent concentration in the extract on the improvement of dyslipidemia induced by high fat diet in rats

inferred← citeshttps://doi.org/10.1007/s10735-025-10693-zopenalex-snapshot

Maternal high-fat diet and its multigenerational impact on hypertension and metabolic alterations in Wistar rat offspring

inferred← citeshttps://doi.org/10.1007/s11010-010-0571-xopenalex-snapshot

Up-regulation of stearoyl-CoA desaturase 1 and elongase 6 genes expression in rat lipogenic tissues by chronic food restriction and chronic food restriction/refeeding

inferred← citeshttps://doi.org/10.1007/s11101-023-09912-wopenalex-snapshot

Ameliorative role of bioactive phytoconstituents targeting obesity associated NAFLD by modulation of inflammation and lipogenesis pathways: a comprehensive review

inferred← citeshttps://doi.org/10.1007/s11160-012-9288-0openalex-snapshot

Characteristics and metabolism of different adipose tissues in fish

inferred← citeshttps://doi.org/10.1007/s11357-021-00342-0openalex-snapshot

Circulating fatty acids and endocannabinoidome-related mediator profiles associated to human longevity

inferred← citeshttps://doi.org/10.1007/s11418-016-0968-2openalex-snapshot

Inhibitory effects of compounds isolated from the dried branches and leaves of murta (Myrceugenia euosma) on lipid accumulation in 3T3-L1 cells

inferred← citeshttps://doi.org/10.1007/s11427-016-0322-xopenalex-snapshot

The size matters: regulation of lipid storage by lipid droplet dynamics

inferred← citeshttps://doi.org/10.1007/s11745-010-3521-1openalex-snapshot

Insulin Stimulates Lipogenesis and Attenuates Beta‐Oxidation in White Adipose Tissue of Fed Rainbow Trout

inferred← citeshttps://doi.org/10.1007/s11745-013-3786-2openalex-snapshot

Up‐Regulation of Stearoyl‐CoA Desaturase 1 Increases Liver MUFA Content in Obese Zucker but Not Goto‐Kakizaki Rats

inferred← citeshttps://doi.org/10.1007/s11745-014-3894-7openalex-snapshot

Cross‐Sectional Associations of Food Consumption with Plasma Fatty Acid Composition and Estimated Desaturase Activities in Finnish Children

inferred← citeshttps://doi.org/10.1007/s11745-015-4090-0openalex-snapshot

Tissue Specific Effects of Dietary Carbohydrates and Obesity on ChREBPα and ChREBPβ Expression

inferred← citeshttps://doi.org/10.1007/s11745-016-4199-9openalex-snapshot

Fatty Acid de Novo Synthesis in Adult Intrauterine Growth‐Restricted Offspring, and Adult Male Response to a High Fat Diet

inferred← citeshttps://doi.org/10.1007/s11892-015-0607-4openalex-snapshot

Nonalcoholic Fatty Liver Disease and Type 2 Diabetes: Common Pathophysiologic Mechanisms

inferred← citeshttps://doi.org/10.1007/s12010-024-05170-4openalex-snapshot

Therapeutic Potential of Suaeda japonica Makino Leaf Extract Against Obesity in 3T3-L1 Preadipocytes and HFD-Induced C57BL/6 J Mice

inferred← citeshttps://doi.org/10.1007/s12011-018-1542-4openalex-snapshot

Effect of Duration of Exposure to Fluoride and Type of Diet on Lipid Parameters and De Novo Lipogenesis

inferred← citeshttps://doi.org/10.1007/s12020-012-9815-8openalex-snapshot

Fructose intake during pregnancy up-regulates the expression of maternal and fetal hepatic sterol regulatory element-binding protein-1c in rats

inferred← citeshttps://doi.org/10.1007/s12170-014-0379-4openalex-snapshot

Review Article: An Adipocentric View of the Metabolic Syndrome and Cardiovascular Disease

inferred← citeshttps://doi.org/10.1007/s12263-012-0300-zopenalex-snapshot

Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet

inferred← citeshttps://doi.org/10.1007/s12263-012-0329-zopenalex-snapshot

Altered expression of genes involved in lipid metabolism in obese subjects with unfavourable phenotype

inferred← citeshttps://doi.org/10.1007/s12562-017-1104-2openalex-snapshot

Effects of temperature on growth and fatty acid synthesis in the cyclopoid copepod Paracyclopina nana

inferred← citeshttps://doi.org/10.1007/s13105-014-0313-8openalex-snapshot

Resveratrol does not increase body fat loss induced by energy restriction

inferred← citeshttps://doi.org/10.1007/s13105-015-0419-7openalex-snapshot

Over-nutrient environment during both prenatal and postnatal development increases severity of islet injury, hyperglycemia, and metabolic disorders in the offspring

inferred← citeshttps://doi.org/10.1007/s13668-013-0046-2openalex-snapshot

Nutritional Genetics and Energy Metabolism in Human Obesity

inferred← citeshttps://doi.org/10.1007/s13668-014-0077-3openalex-snapshot

Deconstructing the Paleolithic Diet: Components that Reduce Cardiovascular Disease Risk

inferred← citeshttps://doi.org/10.1007/s13679-025-00626-yopenalex-snapshot

Understanding the Link Between Sterol Regulatory Element Binding Protein (SREBPs) and Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD)

inferred← citeshttps://doi.org/10.1016/b978-0-12-811752-1.00004-3openalex-snapshot

Nutritional Regulation of Mitochondrial Function

inferred← citeshttps://doi.org/10.1016/j.abst.2025.11.005openalex-snapshot

Mechanistic insights on effective ratio of Linoelaidic and Docosapentaenoic acid by modulating adipogenic and inflammatory biomarkers in 3T3-L1 preadipocytes

inferred← citeshttps://doi.org/10.1016/j.ajpath.2021.05.020openalex-snapshot

Vitamin C Deficiency Inhibits Nonalcoholic Fatty Liver Disease Progression through Impaired de Novo Lipogenesis

inferred← citeshttps://doi.org/10.1016/j.apjtb.2015.12.006openalex-snapshot

Anti-lipogenic effect of Senna alata leaf extract in high-fat diet-induced obese mice

inferred← citeshttps://doi.org/10.1016/j.aqrep.2026.103850openalex-snapshot

Partial replacement of fish meal with Yarrowia lipolytica alters hepatic lipid metabolism in turbot (Scophthalmus maximus): Potential involvement of the C/EBPα–Apoea axis

inferred← citeshttps://doi.org/10.1016/j.aquaculture.2016.02.007openalex-snapshot

Utilisation of dietary carbohydrates in farmed fishes: New insights on influencing factors, biological limitations and future strategies

inferred← citeshttps://doi.org/10.1016/j.aquatox.2016.07.002openalex-snapshot

A brominated flame retardant 2,2⿲,4,4⿲ tetrabrominated diphenyl ether (BDE-47) leads to lipogenesis in the copepod Tigriopus japonicus

inferred← citeshttps://doi.org/10.1016/j.aquatox.2016.10.025openalex-snapshot

BDE-47 induces oxidative stress, activates MAPK signaling pathway, and elevates de novo lipogenesis in the copepod Paracyclopina nana

inferred← citeshttps://doi.org/10.1016/j.arcmed.2024.102986openalex-snapshot

Role of Angiotensin II in Non-Alcoholic Steatosis Development

inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2024.119066openalex-snapshot

De novo lipid synthesis in cardiovascular tissue and disease

inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.01.006openalex-snapshot

Long-term dietary effects on substrate selection and muscle fiber type in very-long-chain acyl-CoA dehydrogenase deficient (VLCAD−/−) mice

inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.04.024openalex-snapshot

Animal models of NAFLD from the pathologist's point of view

inferred← citeshttps://doi.org/10.1016/j.bbalip.2011.06.001openalex-snapshot

Lipid metabolism in mammalian tissues and its control by retinoic acid

inferred← citeshttps://doi.org/10.1016/j.bbalip.2016.07.012openalex-snapshot

SCD1 deficiency protects mice against ethanol-induced liver injury

inferred← citeshttps://doi.org/10.1016/j.bbalip.2018.08.001openalex-snapshot

Spexin: A novel regulator of adipogenesis and fat tissue metabolism

inferred← citeshttps://doi.org/10.1016/j.bbalip.2019.158582openalex-snapshot

A high-fat diet enriched in medium chain triglycerides triggers hepatic thermogenesis and improves metabolic health in lean and obese mice

inferred← citeshttps://doi.org/10.1016/j.bbalip.2021.159018openalex-snapshot

The effects of neuronostatin on proliferation and differentiation of rat primary preadipocytes and 3T3-L1 cells

inferred← citeshttps://doi.org/10.1016/j.bbalip.2023.159348openalex-snapshot

Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets

inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.03.048openalex-snapshot

Ablation of prolactin receptor increases hepatic triglyceride accumulation

inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.07.121openalex-snapshot

CPT1a downregulation protects against cholesterol-induced fibrosis in tubular epithelial cells by downregulating TGFβ-1 and inflammasome

inferred← citeshttps://doi.org/10.1016/j.bbrc.2020.01.143openalex-snapshot

MicroRNA-103 represses hepatic de novo lipogenesis and alleviates NAFLD via targeting FASN and SCD1

inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.06.040openalex-snapshot

MIG12 is involved in the LXR activation-mediated induction of the polymerization of mammalian acetyl-CoA carboxylase

inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.08.092openalex-snapshot

The role of Stearoyl-CoA desaturase in hepatic de novo lipogenesis

inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.02.018openalex-snapshot

Hepatic oleate regulates one-carbon metabolism during high carbohydrate feeding

inferred← citeshttps://doi.org/10.1016/j.bbrep.2026.102499openalex-snapshot

Anti-cancer effect of palmitic acid against the endometrial cancer progression via inducing ferroptosis

inferred← citeshttps://doi.org/10.1016/j.bcdf.2016.01.002openalex-snapshot

Gum arabic suppressed diet-induced obesity by alteration the expression of mRNA levels of genes involved in lipid metabolism in mouse liver

inferred← citeshttps://doi.org/10.1016/j.bcp.2018.02.022openalex-snapshot

Lipid bilayer stress in obesity-linked inflammatory and metabolic disorders

inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116116openalex-snapshot

The pathophysiology of visceral adipose tissues in cardiometabolic diseases

inferred← citeshttps://doi.org/10.1016/j.biocel.2012.12.019openalex-snapshot

Stat3 pathway correlates with the roles of leptin in mouse liver fibrosis and sterol regulatory element binding protein-1c expression of rat hepatic stellate cells

inferred← citeshttps://doi.org/10.1016/j.biocel.2021.106053openalex-snapshot

Loss of lymphocyte cytosolic protein 1 (LCP1) induces browning in 3T3-L1 adipocytes via β3-AR and the ERK-independent signaling pathway

inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109156openalex-snapshot

Prophylactic and therapeutic role of Betulin in mitigating obesity-related metabolic dysfunction in rats fed on high-fat diet

inferred← citeshttps://doi.org/10.1016/j.biopha.2021.111969openalex-snapshot

Protective effects of p-coumaric acid against high-fat diet-induced metabolic dysregulation in mice

inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117575openalex-snapshot

The potential role of transcription factor sterol regulatory element binding proteins (SREBPs) in Alzheimer's disease

inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118633openalex-snapshot

The pathogenesis of metabolic dysfunction-associated steatotic liver disease and nucleoside reverse transcriptase inhibitors (NRTIs) -based HIV-antiretroviral regimens: A comprehensive narrative review

inferred← citeshttps://doi.org/10.1016/j.cbi.2018.04.023openalex-snapshot

Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase

inferred← citeshttps://doi.org/10.1016/j.cbi.2018.08.025openalex-snapshot

Deoxypodophyllotoxin in Anthriscus sylvestris alleviates fat accumulation in the liver via AMP-activated protein kinase, impeding SREBP-1c signal

inferred← citeshttps://doi.org/10.1016/j.cbi.2026.112012openalex-snapshot

β-Nicotinamide mononucleotide prevents senescence and lipid accumulation in hepatic stellate cells by restoring SIRT1 function

inferred← citeshttps://doi.org/10.1016/j.cbpb.2010.08.007openalex-snapshot

Effects of early neonatal development and delayed feeding immediately post-hatch on the hepatic lipogenic program in broiler chicks

inferred← citeshttps://doi.org/10.1016/j.cbpb.2012.05.014openalex-snapshot

De novo lipogenesis in the liver and adipose tissues of ducks during early growth stages after hatching

inferred← citeshttps://doi.org/10.1016/j.cbpb.2015.11.006openalex-snapshot

Expression of mitochondria-related genes is elevated in overfeeding-induced goose fatty liver

inferred← citeshttps://doi.org/10.1016/j.clinre.2016.11.002openalex-snapshot

CD40 signaling and hepatic steatosis: Unanticipated links

inferred← citeshttps://doi.org/10.1016/j.cmet.2015.02.016openalex-snapshot

Lack of Sterol Regulatory Element Binding Factor-1c Imposes Glial Fatty Acid Utilization Leading to Peripheral Neuropathy

inferred← citeshttps://doi.org/10.1016/j.crfs.2021.03.003openalex-snapshot

Long-term intake of ginger protease-degraded collagen hydrolysate reduces blood lipid levels and adipocyte size in mice

inferred← citeshttps://doi.org/10.1016/j.ebiom.2023.104714openalex-snapshot

Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseases

inferred← citeshttps://doi.org/10.1016/j.ejbt.2015.03.009openalex-snapshot

Diet high in α-linolenic acid up-regulate PPAR-α gene expression in the liver of goats

inferred← citeshttps://doi.org/10.1016/j.ejogrb.2015.03.002openalex-snapshot

54G/C polymorphism of SREBF-1 gene is associated with polycystic ovary syndrome

inferred← citeshttps://doi.org/10.1016/j.ejphar.2017.09.010openalex-snapshot

Anti-atherosclerotic effect of hesperidin in LDLr −/− mice and its possible mechanism

inferred← citeshttps://doi.org/10.1016/j.ejphar.2018.04.026openalex-snapshot

Salusin-α attenuates hepatic steatosis and atherosclerosis in high fat diet-fed low density lipoprotein receptor deficient mice

inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.175989openalex-snapshot

Human skin stem cell-derived hepatic cells as in vitro drug discovery model for insulin-driven de novo lipogenesis

inferred← citeshttps://doi.org/10.1016/j.euprot.2015.05.003openalex-snapshot

Deciphering metabolic networks by blue native polyacrylamide gel electrophoresis: A functional proteomic exploration

inferred← citeshttps://doi.org/10.1016/j.exger.2018.01.016openalex-snapshot

Differential response to caloric restriction of retroperitoneal, epididymal, and subcutaneous adipose tissue depots in rats

inferred← citeshttps://doi.org/10.1016/j.fct.2012.04.039openalex-snapshot

Protective potentials of wild rice (Zizania latifolia (Griseb) Turcz) against obesity and lipotoxicity induced by a high-fat/cholesterol diet in rats

inferred← citeshttps://doi.org/10.1016/j.fct.2018.12.006openalex-snapshot

Dietary fish oil supplementation during early pregnancy in rats on a cafeteria-diet prevents fatty liver in adult male offspring

inferred← citeshttps://doi.org/10.1016/j.focha.2023.100430openalex-snapshot

Differences and correlation among various fatty acids of cow milk and goat milk probiotic yoghurt: Gas chromatography, PCA and network based analysis

inferred← citeshttps://doi.org/10.1016/j.foodchem.2012.09.012openalex-snapshot

Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling

inferred← citeshttps://doi.org/10.1016/j.foodres.2018.08.004openalex-snapshot

Bacupari peel extracts (Garcinia brasiliensis) reduces the biometry, lipogenesis and hepatic steatosis in obese rats

inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.01.023openalex-snapshot

Lipid oxidation products in the pathogenesis of non-alcoholic steatohepatitis

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e25263openalex-snapshot

Postbiotic potential of Bacillus velezensis KMU01 cell-free supernatant for the alleviation of obesity in mice

inferred← citeshttps://doi.org/10.1016/j.indcrop.2025.121306openalex-snapshot

VfSCD enhances cold resistance of tung tree through a previously uncovered synthesis pathway of unsaturated fatty acids

inferred← citeshttps://doi.org/10.1016/j.isci.2022.105135openalex-snapshot

Deficiency of peroxisomal NUDT7 stimulates de novo lipogenesis in hepatocytes

inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.12.001openalex-snapshot

Bile Acid–Mediated Activation of Brown Fat Protects From Alcohol-Induced Steatosis and Liver Injury in Mice

inferred← citeshttps://doi.org/10.1016/j.jep.2017.08.032openalex-snapshot

Korean red ginseng ( Panax ginseng ) inhibits obesity and improves lipid metabolism in high fat diet-fed castrated mice

inferred← citeshttps://doi.org/10.1016/j.jep.2022.115806openalex-snapshot

Inhibition on XBP1s-driven lipogenesis by Qushi Huayu Decoction contributes to amelioration of hepatic steatosis induced by fructose

inferred← citeshttps://doi.org/10.1016/j.jep.2023.116789openalex-snapshot

Anti-obesity effect of Lythri herba water extracts in vitro and in vivo

inferred← citeshttps://doi.org/10.1016/j.jff.2015.04.007openalex-snapshot

L-carnitine ameliorates dyslipidemic and hepatic disorders induced by a high-fat diet via regulating lipid metabolism, self-antioxidant capacity, and inflammatory response

inferred← citeshttps://doi.org/10.1016/j.jff.2024.106305openalex-snapshot

HPP-1S attenuates oleic acid-induced steatosis in HepG2 cells and nonalcoholic fatty liver disease in a rat model of high-fat diet-induced obesity

inferred← citeshttps://doi.org/10.1016/j.jhepr.2019.07.002openalex-snapshot

From NASH to diabetes and from diabetes to NASH: Mechanisms and treatment options

inferred← citeshttps://doi.org/10.1016/j.jhepr.2023.100902openalex-snapshot

A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2014.12.011openalex-snapshot

Palmitic acid induces central leptin resistance and impairs hepatic glucose and lipid metabolism in male mice

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2016.09.010openalex-snapshot

High-fructose corn syrup-55 consumption alters hepatic lipid metabolism and promotes triglyceride accumulation

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.09.026openalex-snapshot

Age-dependent alterations of glucose clearance and homeostasis are temporally separated and modulated by dietary fat

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.12.003openalex-snapshot

Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2018.08.011openalex-snapshot

Maternal fructose induces gender-dependent changes in both LXRα promoter methylation and cholesterol metabolism in progeny

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2025.110017openalex-snapshot

Calcitriol/Vitamin D receptor ameliorates fructose-induced enteritis-hepatitis axis dysregulation in mice

inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110647openalex-snapshot

Network Modeling and Inference of Peroxisome Proliferator-Activated Receptor Pathway in High fat diet-linked Obesity

inferred← citeshttps://doi.org/10.1016/j.lfs.2017.09.012openalex-snapshot

High-intensity interval training has beneficial effects on cardiac remodeling through local renin-angiotensin system modulation in mice fed high-fat or high-fructose diets

inferred← citeshttps://doi.org/10.1016/j.livres.2022.06.001openalex-snapshot

Heterogeneous population of macrophages in the development of non-alcoholic fatty liver disease

inferred← citeshttps://doi.org/10.1016/j.mad.2016.07.003openalex-snapshot

Methionine restriction improves renal insulin signalling in aged kidneys

inferred← citeshttps://doi.org/10.1016/j.mcpro.2023.100637openalex-snapshot

CREB-Regulated Transcriptional Coactivator 2 Proteome Landscape is Modulated by SREBF1

inferred← citeshttps://doi.org/10.1016/j.meafoo.2024.100142openalex-snapshot

Advances in therapeutic applications of fish oil: A review

inferred← citeshttps://doi.org/10.1016/j.meatsci.2012.11.019openalex-snapshot

Candidate gene marker associations with fatty acid profiles in heavy pigs

inferred← citeshttps://doi.org/10.1016/j.metabol.2014.04.003openalex-snapshot

De novo lipogenesis in health and disease

inferred← citeshttps://doi.org/10.1016/j.metop.2023.100234openalex-snapshot

SENP2 knockdown in human adipocytes reduces glucose metabolism and lipid accumulation, while increases lipid oxidation

inferred← citeshttps://doi.org/10.1016/j.molmet.2014.02.004openalex-snapshot

Genetic inhibition of hepatic acetyl-CoA carboxylase activity increases liver fat and alters global protein acetylation

inferred← citeshttps://doi.org/10.1016/j.molmet.2019.08.020openalex-snapshot

Fibroblast growth factor 21 is required for the therapeutic effects of Lactobacillus rhamnosus GG against fructose-induced fatty liver in mice

inferred← citeshttps://doi.org/10.1016/j.numecd.2022.09.003openalex-snapshot

Association between de novo lipogenesis susceptibility genes and coronary artery disease

inferred← citeshttps://doi.org/10.1016/j.nut.2012.06.005openalex-snapshot

Azuki bean polyphenols intake during lactation upregulate AMPK in male rat offspring exposed to fetal malnutrition

inferred← citeshttps://doi.org/10.1016/j.nut.2014.03.029openalex-snapshot

Effects of Artemisia species on de novo lipogenesis in vivo

inferred← citeshttps://doi.org/10.1016/j.nut.2018.01.017openalex-snapshot

Magnolol promotes thermogenesis and attenuates oxidative stress in 3T3-L1 adipocytes

inferred← citeshttps://doi.org/10.1016/j.phymed.2019.152935openalex-snapshot

Polydatin attenuates atherosclerosis in apolipoprotein E-deficient mice: Role of reverse cholesterol transport

inferred← citeshttps://doi.org/10.1016/j.psj.2025.105096openalex-snapshot

Identify key transcript factors of adipocyte differentiation in abdominal fat of broilers based on ATAC-seq and RNA-seq

inferred← citeshttps://doi.org/10.1016/j.sajb.2022.05.011openalex-snapshot

Duranta repens L. reverses hepatic and peripheral insulin resistance in fructose-induced hyperinsulinaemic rats – Experimental and computational findings

inferred← citeshttps://doi.org/10.1016/j.steroids.2011.01.009openalex-snapshot

Photo-DHEA—A functional photoreactive dehydroepiandrosterone (DHEA) analog

inferred← citeshttps://doi.org/10.1016/j.tem.2017.10.003openalex-snapshot

Insights into Stearoyl-CoA Desaturase-1 Regulation of Systemic Metabolism

inferred← citeshttps://doi.org/10.1016/j.tifs.2025.105525openalex-snapshot

Next-generation strategies for designing cultured fat with enhanced flavor and functionality

inferred← citeshttps://doi.org/10.1016/j.tips.2015.08.001openalex-snapshot

Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism

inferred← citeshttps://doi.org/10.1016/j.toxlet.2016.12.010openalex-snapshot

Salvianolic acid B protects against chronic alcoholic liver injury via SIRT1-mediated inhibition of CRP and ChREBP in rats

inferred← citeshttps://doi.org/10.1017/s0007114515000811openalex-snapshot

Lipid hydrolysis products affect the composition of infant gut microbial communitiesin vitro

inferred← citeshttps://doi.org/10.1017/s0007114517002501openalex-snapshot

A maternal high-fat, high-sucrose diet alters insulin sensitivity and expression of insulin signalling and lipid metabolism genes and proteins in male rat offspring: effect of folic acid supplementation

inferred← citeshttps://doi.org/10.1017/s1751731116000380openalex-snapshot

Effects of inhibiting PI3K-Akt-mTOR pathway on lipid metabolism homeostasis in goose primary hepatocytes

inferred← citeshttps://doi.org/10.1017/s204017441400035xopenalex-snapshot

Supplementation with methyl donors during lactation to high-fat-sucrose-fed dams protects offspring against liver fat accumulation when consuming an obesogenic diet

inferred← citeshttps://doi.org/10.1017/s2040174419000515openalex-snapshot

The loss of ERE-dependent ERα signaling potentiates the effects of maternal high-fat diet on energy homeostasis in female offspring fed an obesogenic diet

inferred← citeshttps://doi.org/10.1017/s2040174421000416openalex-snapshot

Fetal programming by androgen excess impairs liver lipid content and PPARg expression in adult rats

inferred← citeshttps://doi.org/10.1021/acsnano.6c12691openalex-snapshot

Multimodal Nanoscale Imaging Reveals Cellular and Metabolic Complexity of Human Breast Milk

inferred← citeshttps://doi.org/10.1021/acsptsci.4c00301openalex-snapshot

Lipid Metabolism Modulatory Cisplatin Prodrug Sensitizes Resistant Prostate Cancer toward Androgen Deprivation Therapy

inferred← citeshttps://doi.org/10.1021/jf302757jopenalex-snapshot

Elongation and Desaturation Pathways in Mammary Gland Epithelial Cells Are Associated with Modulation of Fat and Membrane Composition

inferred← citeshttps://doi.org/10.1038/ijo.2017.149openalex-snapshot

Antrodia cinnamomea reduces obesity and modulates the gut microbiota in high-fat diet-fed mice

inferred← citeshttps://doi.org/10.1038/nature14557openalex-snapshot

The CREB coactivator CRTC2 controls hepatic lipid metabolism by regulating SREBP1

inferred← citeshttps://doi.org/10.1038/ncomms3300openalex-snapshot

Overexpression of Atg5 in mice activates autophagy and extends lifespan

inferred← citeshttps://doi.org/10.1038/nrm3293openalex-snapshot

Sirtuins as regulators of metabolism and healthspan

inferred← citeshttps://doi.org/10.1038/s41366-018-0106-1openalex-snapshot

DNA methylation variant, B-vitamins intake and longitudinal change in body mass index

inferred← citeshttps://doi.org/10.1038/s41598-017-06560-xopenalex-snapshot

Loss of ERα partially reverses the effects of maternal high-fat diet on energy homeostasis in female mice

inferred← citeshttps://doi.org/10.1038/s41598-017-15141-xopenalex-snapshot

MicroRNA-27a regulates hepatic lipid metabolism and alleviates NAFLD via repressing FAS and SCD1

inferred← citeshttps://doi.org/10.1038/s41598-018-26701-0openalex-snapshot

Glucose challenge metabolomics implicates medium-chain acylcarnitines in insulin resistance

inferred← citeshttps://doi.org/10.1038/s41598-023-40888-xopenalex-snapshot

Partially defatted rather than native poppy seeds beneficially alter lipid metabolism in rats fed a high-fat diet

inferred← citeshttps://doi.org/10.1038/s41598-025-93438-yopenalex-snapshot

Comprehensive understanding of context-specific functions of PHF2 in lipid metabolic tissues

inferred← citeshttps://doi.org/10.1038/s41598-025-99693-3openalex-snapshot

Integrating microbiome and metabolome analyses to unravel the role of inulin in enhancing the meat quality and bone health of ducks

inferred← citeshttps://doi.org/10.1038/s42003-025-08105-9openalex-snapshot

The metabolic underpinnings of sebaceous lipogenesis

inferred← citeshttps://doi.org/10.1038/s42255-018-0021-8openalex-snapshot

Metabolic adaptation and maladaptation in adipose tissue

inferred← citeshttps://doi.org/10.1038/srep20405openalex-snapshot

Targeting arginase-II protects mice from high-fat-diet-induced hepatic steatosis through suppression of macrophage inflammation

inferred← citeshttps://doi.org/10.1038/srep26242openalex-snapshot

Preventing High Fat Diet-induced Obesity and Improving Insulin Sensitivity through Neuregulin 4 Gene Transfer

inferred← citeshttps://doi.org/10.1038/srep28734openalex-snapshot

New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats

inferred← citeshttps://doi.org/10.1039/c9ra10143hopenalex-snapshot

Protective effects of aqueous extract from Gei Herba on blood-deficiency mice: insights gained by a metabolomic approach

inferred← citeshttps://doi.org/10.1042/bsr20192188openalex-snapshot

Dynamic characteristics of lipid metabolism in cultured granulosa cells from geese follicles at different developmental stages

inferred← citeshttps://doi.org/10.1042/cs20110373openalex-snapshot

Beneficial effects of rosuvastatin on insulin resistance, adiposity, inflammatory markers and non-alcoholic fatty liver disease in mice fed on a high-fat diet

inferred← citeshttps://doi.org/10.1053/j.gastro.2017.08.039openalex-snapshot

Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis

inferred← citeshttps://doi.org/10.1055/a-1087-7405openalex-snapshot

Patchouli Oil Attenuates High Fat Diet-induced Non-alcoholic Hepatic Steatosis

inferred← citeshttps://doi.org/10.1055/a-1150-7446openalex-snapshot

Epigenetic Downregulation of FASN in Visceral Adipose Tissue of Insulin Resistant Subjects

inferred← citeshttps://doi.org/10.1073/pnas.2212220119openalex-snapshot

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila

inferred← citeshttps://doi.org/10.1074/jbc.m113.537191openalex-snapshot

Circadian Control of Fatty Acid Elongation by SIRT1 Protein-mediated Deacetylation of Acetyl-coenzyme A Synthetase 1

inferred← citeshttps://doi.org/10.1074/jbc.m114.592493openalex-snapshot

Fat/Vessel-derived Secretory Protein (Favine)/CCDC3 Is Involved in Lipid Accumulation

inferred← citeshttps://doi.org/10.1074/jbc.m117.782334openalex-snapshot

The retinol-binding protein receptor STRA6 regulates diurnal insulin responses

inferred← citeshttps://doi.org/10.1074/jbc.r114.576355openalex-snapshot

Pathway-selective Insulin Resistance and Metabolic Disease: The Importance of Nutrient Flux

inferred← citeshttps://doi.org/10.1080/09712119.2017.1411264openalex-snapshot

The contributions of hepatic de novo lipogenesis to the difference in body fat mass of genetically lean and fat duck breeds

inferred← citeshttps://doi.org/10.1080/13813455.2020.1743724openalex-snapshot

Spirulina reduces diet-induced obesity through downregulation of lipogenic genes expression in Psammomys obesus

inferred← citeshttps://doi.org/10.1080/15384047.2017.1323597openalex-snapshot

CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice

inferred← citeshttps://doi.org/10.1080/19336896.2020.1729074openalex-snapshot

The role of cellular prion protein in lipid metabolism in the liver

inferred← citeshttps://doi.org/10.1089/ars.2010.3749openalex-snapshot

New Insights from Rodent Models of Fatty Liver Disease

inferred← citeshttps://doi.org/10.1089/jmf.2014.3194openalex-snapshot

Vigna nakashimae Extract Prevents Hepatic Steatosis in Obese Mice Fed High-Fat Diets

inferred← citeshttps://doi.org/10.1089/jmf.2016.3860openalex-snapshot

Fermented Moringa oleifera Decreases Hepatic Adiposity and Ameliorates Glucose Intolerance in High-Fat Diet-Induced Obese Mice

inferred← citeshttps://doi.org/10.1093/advances/nmac097openalex-snapshot

Human Milk Lipid Profiles around the World: A Systematic Review and Meta-Analysis

inferred← citeshttps://doi.org/10.1093/eurheartj/ehx518openalex-snapshot

Fructose metabolism, cardiometabolic risk, and the epidemic of coronary artery disease

inferred← citeshttps://doi.org/10.1093/jmicro/dfac034openalex-snapshot

Glutaraldehyde and uranyl acetate dual fixation combined sputtering/unroofing enables intracellular fatty acids TOF-SIMS imaging with organelle-corresponding subcellular distribution

inferred← citeshttps://doi.org/10.1093/jpp/rgag094openalex-snapshot

Intervention effects and underlying mechanisms of bioactive components from Citrus species on type 2 diabetes and fatty liver diseases: a mechanistic review

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