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GM-CSF Upregulated in Rheumatoid Arthritis Reverses Cognitive Impairment and Amyloidosis in Alzheimer Mice

https://doi.org/10.3233/jad-2010-091471
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT)
inferredcites →https://doi.org/10.1002/1529-0131(200001)43:1<155::aid-anr20>3.0.co;2-3openalex-snapshot
The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide
inferredcites →https://doi.org/10.1002/1529-0131(200103)44:3<541::aid-anr102>3.0.co;2-6openalex-snapshot
Lymph draining from foot joints in rheumatoid arthritis provides insight into local cytokine and chemokine production and transport to lymph nodes
inferredcites →https://doi.org/10.1016/0006-291x(84)91209-9openalex-snapshot
Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
inferredcites →https://doi.org/10.1016/0092-8674(95)90234-1openalex-snapshot
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
inferredcites →https://doi.org/10.1016/j.cell.2005.12.039openalex-snapshot
CRIg: A Macrophage Complement Receptor Required for Phagocytosis of Circulating Pathogens
inferredcites →https://doi.org/10.1016/j.jneumeth.2009.08.021openalex-snapshot
A novel technique for simultaneous bilateral brain infusions in a mouse model of neurodegenerative disease
inferredcites →https://doi.org/10.1016/j.nbd.2004.09.009openalex-snapshot
Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to β-amyloid deposition in APP/PS1 double transgenic Alzheimer mice
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2003.12.011openalex-snapshot
Cognitive impairment in PDAPP mice depends on ApoE and ACT-catalyzed amyloid formation
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2005.09.043openalex-snapshot
Peripheral clearance of amyloid β peptide by complement C3-dependent adherence to erythrocytes
inferredcites →https://doi.org/10.1016/j.neuron.2006.01.022openalex-snapshot
Bone Marrow-Derived Microglia Play a Critical Role in Restricting Senile Plaque Formation in Alzheimer's Disease
inferredcites →https://doi.org/10.1016/j.neuroscience.2009.05.019openalex-snapshot
Sorafenib inhibits nuclear factor kappa B, decreases inducible nitric oxide synthase and cyclooxygenase-2 expression, and restores working memory in APPswe mice
inferredcites →https://doi.org/10.1016/j.neuroscience.2009.05.071openalex-snapshot
Granulocyte colony stimulating factor decreases brain amyloid burden and reverses cognitive impairment in Alzheimer's mice
inferredcites →https://doi.org/10.1016/s0006-8993(00)03186-3openalex-snapshot
Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
inferredcites →https://doi.org/10.1016/s0025-6196(25)18993-3openalex-snapshot
Clinicopathologic Studies of Primary Cerebral Amyloid Angiopathy
inferredcites →https://doi.org/10.1016/s0197-4580(01)00308-6openalex-snapshot
The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation
inferredcites →https://doi.org/10.1017/s1355617704101112openalex-snapshot
Semantic interference deficits and the detection of mild Alzheimer's disease and mild cognitive impairment without dementia
inferredcites →https://doi.org/10.1038/372092a0openalex-snapshot
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
inferredcites →https://doi.org/10.1038/nature06616openalex-snapshot
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
inferredcites →https://doi.org/10.1038/nm1555openalex-snapshot
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
inferredcites →https://doi.org/10.1038/sj.jcbfm.9600496openalex-snapshot
A Neuroprotective Function for the Hematopoietic Protein Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)
inferredcites →https://doi.org/10.1073/pnas.162350199openalex-snapshot
Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice
inferredcites →https://doi.org/10.1073/pnas.86.19.7611openalex-snapshot
Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.
inferredcites →https://doi.org/10.1084/jem.20062481openalex-snapshot
G-CSF rescues the memory impairment of animal models of Alzheimer's disease
inferredcites →https://doi.org/10.1093/brain/120.11.2083openalex-snapshot
Granulocyte-macrophage colony-stimulating factor crosses the blood-- brain and blood--spinal cord barriers
inferredcites →https://doi.org/10.1093/brain/awl255openalex-snapshot
Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons
inferredcites →https://doi.org/10.1093/brain/awn331openalex-snapshot
Powerful beneficial effects of macrophage colony-stimulating factor on -amyloid deposition and cognitive impairment in Alzheimer's disease
inferredcites →https://doi.org/10.1096/fj.04-1517fjeopenalex-snapshot
Bone marrow stem cells have the ability to populate the entire central nervous system into fully differentiated parenchymal microglia
inferredcites →https://doi.org/10.1097/bor.0b013e32805e87aeopenalex-snapshot
Macrophages and their products in rheumatoid arthritis
inferredcites →https://doi.org/10.1111/j.1471-4159.2009.06432.xopenalex-snapshot
Granulocyte‐macrophage colony‐stimulating factor antibody suppresses microglial activity: implications for anti‐inflammatory effects in Alzheimer’s Disease and multiple sclerosis
inferredcites →https://doi.org/10.1111/j.1749-6632.1996.tb34408.xopenalex-snapshot
Regulation of Tau Phosphorylation in Alzheimer's Disease
inferredcites →https://doi.org/10.1126/science.1072994openalex-snapshot
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
inferredcites →https://doi.org/10.1158/0008-5472.can-03-2971openalex-snapshot
Overexpression of the Colony-Stimulating Factor (CSF-1) and/or Its Receptor c-fms in Mammary Glands of Transgenic Mice Results in Hyperplasia and Tumor Formation
inferredcites →https://doi.org/10.1161/01.str.0000259707.43496.71openalex-snapshot
Granulocyte-Macrophage Colony-Stimulating Factor–Induced Vessel Growth Restores Cerebral Blood Supply After Bilateral Carotid Artery Occlusion
inferredcites →https://doi.org/10.1172/jci112087openalex-snapshot
Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity.
inferredcites →https://doi.org/10.1172/jci113971openalex-snapshot
Cytokines in chronic inflammatory arthritis. II. Granulocyte-macrophage colony-stimulating factor in rheumatoid synovial effusions.
inferredcites →https://doi.org/10.1177/153537020322800101openalex-snapshot
Erythropoietin: Physiology and Pharmacology Update
inferredcites →https://doi.org/10.1186/1471-2202-8-88openalex-snapshot
The hematopoietic factor GM-CSF (Granulocyte-macrophage colony-stimulating factor) promotes neuronal differentiation of adult neural stem cells in vitro
inferredcites →https://doi.org/10.1186/ar2406openalex-snapshot
Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha
inferredcites →https://doi.org/10.1272/jnms1923.62.260openalex-snapshot
Macrophage colony-stimulating factor in patients with rheumatoid arthritis.
inferredcites →https://doi.org/10.1523/jneurosci.0616-08.2008openalex-snapshot
Microglial Dysfunction and Defective β-Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
inferredcites →https://doi.org/10.1523/jneurosci.4147-08.2008openalex-snapshot
Rapid Microglial Response Around Amyloid Pathology after Systemic Anti-Aβ Antibody Administration in PDAPP Mice
inferredcites →https://doi.org/10.3233/jad-2006-9s330openalex-snapshot
Inflammation, anti-inflammatory agents and Alzheimer disease: The last 12 years
inferredcites →https://doi.org/10.4049/jimmunol.180.11.7414openalex-snapshot
Both Th1 and Th17 Are Immunopathogenic but Differ in Other Key Biological Activities

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4050072openalex-extracted
Increased Expression of KIF11/Kinesin5 Offsets Alzheimer Aβ-Mediated Toxicity and Cognitive Dysfunction in Cell Culture, Mice, and Humans
inferred← citeshttps://doi.org/10.1002/0471266949.bmc242.pub2openalex-snapshot
Cognition
inferred← citeshttps://doi.org/10.1002/9781119356752.ch14openalex-snapshot
Current and Prospective Treatments for Alzheimer's Disease (and Other Neurodegenerative Diseases)
inferred← citeshttps://doi.org/10.1002/acr.23243openalex-snapshot
Cognitive Impairment in Rheumatoid Arthritis: A Systematic Review
inferred← citeshttps://doi.org/10.1002/btpr.2071openalex-snapshot
Engineering superactive granulocyte macrophage colony‐stimulating factor transferrin fusion proteins as orally‐delivered candidate agents for treating neurodegenerative disease
inferred← citeshttps://doi.org/10.1002/jnr.23714openalex-snapshot
Granulocyte colony‐stimulating factor promotes behavioral recovery in a mouse model of traumatic brain injury
inferred← citeshttps://doi.org/10.1002/trc2.12158openalex-snapshot
Safety and efficacy of sargramostim (GM‐CSF) in the treatment of Alzheimer's disease
inferred← citeshttps://doi.org/10.1007/978-3-031-68237-7_50openalex-snapshot
Immune Transformations for Therapeutic Gain in Neurodegenerative Disease
inferred← citeshttps://doi.org/10.1007/bf03284025openalex-snapshot
Granulocyte-macrophage colony-stimulating factor
inferred← citeshttps://doi.org/10.1007/s00393-018-0504-8openalex-snapshot
Causal association between rheumatoid arthritis and a decreased risk of Alzheimer’s disease
inferred← citeshttps://doi.org/10.1007/s00401-013-1182-xopenalex-snapshot
Microglia actions in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1007/s00702-012-0794-yopenalex-snapshot
Distribution of granulocyte–monocyte colony-stimulating factor and its receptor α-subunit in the adult human brain with specific reference to Alzheimer’s disease
inferred← citeshttps://doi.org/10.1007/s10787-023-01397-5openalex-snapshot
Rheumatoid arthritis is a protective factor against Alzheimer’s disease: a bidirectional two-sample Mendelian randomization study
inferred← citeshttps://doi.org/10.1007/s10930-020-09894-0openalex-snapshot
Characterization of a Long-Acting Site-Specific PEGylated Murine GM-CSF Analog and Analysis of Its Hematopoietic Properties in Normal and Cyclophosphamide-Treated Neutropenic Rats
inferred← citeshttps://doi.org/10.1007/s11910-015-0531-7openalex-snapshot
The Role of Neuroinflammation in Dementias
inferred← citeshttps://doi.org/10.1007/s12017-014-8297-7openalex-snapshot
Growth Factors and Synaptic Plasticity in Relapsing–Remitting Multiple Sclerosis
inferred← citeshttps://doi.org/10.1007/s13311-019-00715-6openalex-snapshot
Can Disease-Modifying Anti-Rheumatic Drugs Reduce the Risk of Developing Dementia in Patients with Rheumatoid Arthritis?
inferred← citeshttps://doi.org/10.1007/s42452-026-08439-xopenalex-snapshot
Expanding horizons of immunotherapy: from oncology to multisystemic applications
inferred← citeshttps://doi.org/10.1016/b978-0-12-394816-8.00007-6openalex-snapshot
Beyond Amyloid
inferred← citeshttps://doi.org/10.1016/b978-0-12-802810-0.00013-1openalex-snapshot
Alzheimer’s Disease Drugs in Clinical Trials
inferred← citeshttps://doi.org/10.1016/b978-0-443-30008-0.00014-4openalex-snapshot
Anti-inflammatory and immunomodulating agents
inferred← citeshttps://doi.org/10.1016/j.bbi.2019.01.004openalex-snapshot
CREB signals as PBMC-based biomarkers of cognitive dysfunction: A novel perspective of the brain-immune axis
inferred← citeshttps://doi.org/10.1016/j.bbi.2024.08.003openalex-snapshot
Colony-stimulating factor 2 (CSF2) as a gut microbiome dependent immune factor that alters molecular and behavioral responses to cocaine in male mice
inferred← citeshttps://doi.org/10.1016/j.bbi.2026.106561openalex-snapshot
Suppressed brain-derived neurotrophic factor response to 6 min walking exercise in mild cognitive impairment
inferred← citeshttps://doi.org/10.1016/j.bbr.2016.01.032openalex-snapshot
Isoflurane in the presence or absence of surgery increases hippocampal cytokines associated with memory deficits and responses to brain injury in rats
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.08.028openalex-snapshot
Exosomal biomarkers in Down syndrome and Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.isci.2022.105288openalex-snapshot
Increased KIF11/kinesin-5 expression offsets Alzheimer Aβ-mediated toxicity and cognitive dysfunction
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2013.10.009openalex-snapshot
GM-CSF induces neuroprotective and anti-inflammatory responses in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine intoxicated mice
inferred← citeshttps://doi.org/10.1016/j.jneuroim.2018.03.009openalex-snapshot
Granulocyte-macrophage colony-stimulating factor neuroprotective activities in Alzheimer’s disease mice
inferred← citeshttps://doi.org/10.1016/j.jocn.2019.08.027openalex-snapshot
Cognitive impairment in patients with rheumatoid arthritis
inferred← citeshttps://doi.org/10.1016/j.nbd.2022.105694openalex-snapshot
The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice
inferred← citeshttps://doi.org/10.1016/j.neuint.2016.01.003openalex-snapshot
The Toll-like receptor 4-activated neuroprotective microglia subpopulation survives via granulocyte macrophage colony-stimulating factor and JAK2/STAT5 signaling
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2011.04.012openalex-snapshot
Long-term electromagnetic field treatment enhances brain mitochondrial function of both Alzheimer's transgenic mice and normal mice: a mechanism for electromagnetic field-induced cognitive benefit?
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2022.108119openalex-snapshot
Blood-brain barrier leakage in Alzheimer’s disease: From discovery to clinical relevance
inferred← citeshttps://doi.org/10.1016/j.scib.2024.09.022openalex-snapshot
Blood-derived factors to brain communication in brain diseases
inferred← citeshttps://doi.org/10.1016/j.smim.2021.101511openalex-snapshot
Colony stimulating factors in the nervous system
inferred← citeshttps://doi.org/10.1016/j.xcrm.2025.102525openalex-snapshot
Blood measure of neuronal death is exponentially higher with age, especially in females, and halted in Alzheimer’s disease by GM-CSF treatment
inferred← citeshttps://doi.org/10.1016/j.ymthe.2019.03.010openalex-snapshot
A Novel Endogenous Damage Signal, CSF-2, Activates Multiple Beneficial Functions of Adipose Tissue-Derived Mesenchymal Stem Cells
inferred← citeshttps://doi.org/10.1038/mp.2016.111openalex-snapshot
Reduced pCREB in Alzheimer’s disease prefrontal cortex is reflected in peripheral blood mononuclear cells
inferred← citeshttps://doi.org/10.1038/nature22067openalex-snapshot
Human umbilical cord plasma proteins revitalize hippocampal function in aged mice
inferred← citeshttps://doi.org/10.1038/s41392-025-02145-7openalex-snapshot
Antiageing strategy for neurodegenerative diseases: from mechanisms to clinical advances
inferred← citeshttps://doi.org/10.1038/s41467-024-47683-wopenalex-snapshot
Bacteroidota inhibit microglia clearance of amyloid-beta and promote plaque deposition in Alzheimer’s disease mouse models
inferred← citeshttps://doi.org/10.1038/s41582-024-01046-7openalex-snapshot
Immune mechanisms and shared immune targets in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1038/s41583-019-0255-9openalex-snapshot
Systemic factors as mediators of brain homeostasis, ageing and neurodegeneration
inferred← citeshttps://doi.org/10.1038/s41593-022-01238-8openalex-snapshot
Blood-to-brain communication in aging and rejuvenation
inferred← citeshttps://doi.org/10.1038/s41593-024-01847-5openalex-snapshot
Monocyte-derived macrophages act as reinforcements when microglia fall short in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41593-025-02117-8openalex-snapshot
A myeloid trisomy 21-associated gene variant is protective from Alzheimer’s disease
inferred← citeshttps://doi.org/10.1038/s41593-026-02417-7openalex-snapshot
Bone marrow myelopoiesis dysfunction in Alzheimer’s disease limits monocyte homing to the brain and drives disease progression
inferred← citeshttps://doi.org/10.1038/srep00697openalex-snapshot
The hematopoietic cytokine granulocyte-macrophage colony stimulating factor is important for cognitive functions
inferred← citeshttps://doi.org/10.1080/13543784.2026.2710112openalex-snapshot
Cognitive-enhancing drugs in Phase II clinical trials for Alzheimer’s disease: emerging therapeutic candidates
inferred← citeshttps://doi.org/10.1080/14737175.2017.1326818openalex-snapshot
Emerging treatments for Alzheimer’s disease for non-amyloid and non-tau targets
inferred← citeshttps://doi.org/10.1089/neu.2013.3106openalex-snapshot
Granulocyte-Macrophage Colony-Stimulating Factor Is Neuroprotective in Experimental Traumatic Brain Injury
inferred← citeshttps://doi.org/10.1093/jmcb/mjt028openalex-snapshot
A deficiency in CCR2+ monocytes: the hidden side of Alzheimer's disease
inferred← citeshttps://doi.org/10.1093/protein/gzv022openalex-snapshot
pH responsive granulocyte colony-stimulating factor variants with implications for treating Alzheimer's disease and other central nervous system disorders
inferred← citeshttps://doi.org/10.1101/2021.07.04.451073openalex-snapshot
Pro-inflammatory Cytokine GM-CSF Improves Learning/Memory and Brain Pathology in Dp16 Down Syndrome Mice and Improves Learning/Memory in Wild-Type Mice
inferred← citeshttps://doi.org/10.1101/2021.09.09.459627openalex-snapshot
Kif11 overexpression rescues cognition, long-term potentiation, and spine defects in mouse and cell models of Alzheimer’s disease
inferred← citeshttps://doi.org/10.1101/2024.03.12.584646openalex-snapshot
A Trisomy 21-linked Hematopoietic Gene Variant in Microglia Confers Resilience in Human iPSC Models of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1101/2024.07.14.24310223openalex-snapshot
Neuron loss in the brain starts in childhood, increases exponentially with age and is halted by GM-CSF treatment in Alzheimer’s disease
inferred← citeshttps://doi.org/10.1101/2025.10.06.680030openalex-snapshot
Alzheimer’s disease causes bone marrow myelopoiesis dysfunction
inferred← citeshttps://doi.org/10.1101/cshperspect.a028514openalex-snapshot
Role of the β Common (βc) Family of Cytokines in Health and Disease
inferred← citeshttps://doi.org/10.1111/1756-185x.13273openalex-snapshot
Chikungunya: A rheumatologist's perspective
inferred← citeshttps://doi.org/10.1111/bph.14546openalex-snapshot
The involvement of microglia in Alzheimer's disease: a new dog in the fight
inferred← citeshttps://doi.org/10.1111/nan.12002openalex-snapshot
Review: Experimental manipulations of microglia in mouse models of A lzheimer's pathology: activation reduces amyloid but hastens tau pathology
inferred← citeshttps://doi.org/10.1128/jvi.01805-22openalex-snapshot
Treatment with Granulocyte-Macrophage Colony-Stimulating Factor Reduces Viral Titers in the Brains of West Nile Virus-Infected Mice and Improves Survival
inferred← citeshttps://doi.org/10.1136/rmdopen-2025-006685openalex-snapshot
Cognitive impairment risk in patients with rheumatoid arthritis: a population-based cohort study
inferred← citeshttps://doi.org/10.1155/2012/489428openalex-snapshot
Apolipoprotein E: Essential Catalyst of the Alzheimer Amyloid Cascade
inferred← citeshttps://doi.org/10.1155/2016/8102478openalex-snapshot
Therapeutic Potential of Dental Pulp Stem Cell Secretome for Alzheimer’s Disease Treatment: An In Vitro Study
inferred← citeshttps://doi.org/10.1159/000178810openalex-snapshot
Chronically Administered Immunotherapy with Low-Dose IL-2 and IFN-α in Metastatic Renal Cell Carcinoma: A Feasible Option for Patients with a Good Prognostic Profile
inferred← citeshttps://doi.org/10.1159/000358437openalex-snapshot
Premature Immunosenescence Is Associated with Memory Dysfunction in Rheumatoid Arthritis
inferred← citeshttps://doi.org/10.11606/t.17.2021.tde-28012022-120553openalex-snapshot
Efeitos crônicos da infecção pelo vírus da Chikungunya na modulação da resposta imune e persistência viral
inferred← citeshttps://doi.org/10.1172/jci58656openalex-snapshot
The immunology of neurodegeneration
inferred← citeshttps://doi.org/10.1179/1743132811y.0000000069openalex-snapshot
Neurorestoration therapeutics for neurodegenerative and psychiatric disease
inferred← citeshttps://doi.org/10.1186/1471-2202-12-106openalex-snapshot
Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice
inferred← citeshttps://doi.org/10.1186/1744-8069-9-48openalex-snapshot
Transcriptional Mechanisms Underlying Sensitization of Peripheral Sensory Neurons by Granulocyte-/Granulocyte-Macrophage Colony Stimulating Factors
inferred← citeshttps://doi.org/10.1186/preaccept-1067356402138341openalex-snapshot
Should development of Alzheimer¿s disease-specific intravenous immunoglobulin be considered?
inferred← citeshttps://doi.org/10.1186/s13024-018-0284-2openalex-snapshot
Peripheral immune system in aging and Alzheimer’s disease
inferred← citeshttps://doi.org/10.1186/s13195-015-0117-2openalex-snapshot
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research
inferred← citeshttps://doi.org/10.1248/cpb.c23-00464openalex-snapshot
Neuroimmune Dysfunction in Alzheimer’s Disease and Other Forms of Dementia
inferred← citeshttps://doi.org/10.12688/f1000research.23729.1openalex-snapshot
Recruiting the innate immune system with GM-CSF to fight viral diseases, including West Nile Virus encephalitis and COVID-19
inferred← citeshttps://doi.org/10.1371/journal.pntd.0001446openalex-snapshot
Chikungunya Disease: Infection-Associated Markers from the Acute to the Chronic Phase of Arbovirus-Induced Arthralgia
inferred← citeshttps://doi.org/10.1371/journal.pone.0045535openalex-snapshot
Unveiling Clusters of RNA Transcript Pairs Associated with Markers of Alzheimer’s Disease Progression
inferred← citeshttps://doi.org/10.1371/journal.pone.0049468openalex-snapshot
Cell Therapy: A Safe and Efficacious Therapeutic Treatment for Alzheimer’s Disease in APP+PS1 Mice
inferred← citeshttps://doi.org/10.1371/journal.pone.0168106openalex-snapshot
Rheumatoid Arthritis Was Negatively Associated with Alzheimer’s Disease: A Population-Based Case-Control Study
inferred← citeshttps://doi.org/10.1371/journal.pone.0184697openalex-snapshot
Three-way interaction model to trace the mechanisms involved in Alzheimer’s disease transgenic mice
inferred← citeshttps://doi.org/10.1371/journal.pone.0323674openalex-snapshot
Granulocyte-macrophage colony-stimulating factor reduces lung bacterial load following traumatic brain injury and hemorrhage polytrauma in a juvenile rat model
inferred← citeshttps://doi.org/10.14283/jpad.2024.100openalex-snapshot
Non-Genetic Risk Factors of Alzheimer's Disease: An Updated Umbrella Review
inferred← citeshttps://doi.org/10.14336/ad.2020.0201openalex-snapshot
Reparative Effects of Stem Cell Factor and Granulocyte Colony-Stimulating Factor in Aged APP/PS1 Mice
inferred← citeshttps://doi.org/10.15252/embj.201694591openalex-snapshot
Young microglia restore amyloid plaque clearance of aged microglia
inferred← citeshttps://doi.org/10.1615/critrevimmunol.2022045080openalex-snapshot
Regulatory T Cell Therapeutics for Neuroinflammatory Disorders
inferred← citeshttps://doi.org/10.17816/nb34654openalex-snapshot
Role of the immune response in the pathogenesis of Alzheimer’s disease and possibilities of anti-inflammatory therapy
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1213395/v1openalex-snapshot
GM-CSF Promotes Immune Response and Survival in a Mouse Model of COVID-19
inferred← citeshttps://doi.org/10.2174/1567205016666190301111120openalex-snapshot
Pharmacological Interventions to Attenuate Alzheimer’s Disease Progression: The Story So Far
inferred← citeshttps://doi.org/10.2174/1567205016666190321154618openalex-snapshot
Systemic and CNS Inflammation Crosstalk: Implications for Alzheimer’s Disease
inferred← citeshttps://doi.org/10.2174/1570159x12666140828220938openalex-snapshot
Noradrenergic Regulation of Glial Activation: Molecular Mechanisms and Therapeutic Implications
inferred← citeshttps://doi.org/10.2174/1871527311312050008openalex-snapshot
Innate Immunity in Alzheimer’s Disease: A Complex Affair
inferred← citeshttps://doi.org/10.2217/fnl.12.6openalex-snapshot
Clearance of Amyloid-β Peptides By Microglia and Macrophages: the Issue of What, When and Where
inferred← citeshttps://doi.org/10.22215/etd/2018-14442openalex-snapshot
mGluR5 Modulation as a Treatment for Parkinson’s Disease
inferred← citeshttps://doi.org/10.22541/au.170667577.79095000/v1openalex-snapshot
Reevaluation of EPO and its Derivatives Centering on β Common Receptor
inferred← citeshttps://doi.org/10.31579/2692-9406/128openalex-snapshot
Recent Treatment Strategies in Alzheimer's Disease and Chronic Traumatic Encephalopathy
inferred← citeshttps://doi.org/10.3233/adr-190137openalex-snapshot
Nature’s Derivative(s) as Alternative Anti-Alzheimer’s Disease Treatments
inferred← citeshttps://doi.org/10.3233/bpl-230154openalex-snapshot
Effects of Intravenously Administered Plasma from Exercise-Trained Donors on Microglia and Cytokines in a Transgenic Rat Model of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3233/jad-190872openalex-snapshot
A Review of the Brain-Gut-Microbiome Axis and the Potential Role of Microbiota in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3233/jad-2011-110110openalex-snapshot
Caffeine Synergizes with Another Coffee Component to Increase Plasma GCSF: Linkage to Cognitive Benefits in Alzheimer's Mice
inferred← citeshttps://doi.org/10.3233/jad-220057openalex-snapshot
Peripheral Immune Cells and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease Pathology in Cognitively Intact Older Adults: The CABLE Study
inferred← citeshttps://doi.org/10.3233/rnn-150607openalex-snapshot
Granulocyte-colony stimulating factor promotes brain repair following traumatic brain injury by recruitment of microglia and increasing neurotrophic factor expression
inferred← citeshttps://doi.org/10.3389/fimmu.2021.706186openalex-snapshot
Sargramostim (rhu GM-CSF) as Cancer Therapy (Systematic Review) and An Immunomodulator. A Drug Before Its Time?
inferred← citeshttps://doi.org/10.3389/fnagi.2015.00126openalex-snapshot
Hematopoietic cytokines as therapeutic players in early stages Parkinson’s disease
inferred← citeshttps://doi.org/10.3389/fnagi.2018.00312openalex-snapshot
Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3389/fnagi.2021.718426openalex-snapshot
Innate Immune System Activation and Neuroinflammation in Down Syndrome and Neurodegeneration: Therapeutic Targets or Partners?
inferred← citeshttps://doi.org/10.3389/fnagi.2022.829049openalex-snapshot
Transcranial Electromagnetic Treatment “Rebalances” Blood and Brain Cytokine Levels in Alzheimer’s Patients: A New Mechanism for Reversal of Their Cognitive Impairment
inferred← citeshttps://doi.org/10.3389/fncel.2012.00051openalex-snapshot
Age-related changes in synaptic markers and monocyte subsets link the cognitive decline of APPSwe/PS1 mice
inferred← citeshttps://doi.org/10.3389/fncel.2020.00149openalex-snapshot
Targeting Microglial Population Dynamics in Alzheimer’s Disease: Are We Ready for a Potential Impact on Immune Function?
inferred← citeshttps://doi.org/10.3389/fnins.2024.1528374openalex-snapshot
Low-dose intranasal deferoxamine modulates memory, neuroinflammation, and the neuronal transcriptome in the streptozotocin rodent model of Alzheimer’s disease
inferred← citeshttps://doi.org/10.3389/fphar.2023.1196413openalex-snapshot
Alzheimer’s disease and neuroinflammation: will new drugs in clinical trials pave the way to a multi-target therapy?
inferred← citeshttps://doi.org/10.3389/fphys.2018.01520openalex-snapshot
Repurposing Proteostasis-Modifying Drugs to Prevent or Treat Age-Related Dementia: A Systematic Review
inferred← citeshttps://doi.org/10.3389/fvets.2022.918961openalex-snapshot
Promising prospective effects of Withania somnifera on broiler performance and carcass characteristics: A comprehensive review
inferred← citeshttps://doi.org/10.3390/biom14070827openalex-snapshot
Single-Cell RNA Sequencing Reveals Immunomodulatory Effects of Stem Cell Factor and Granulocyte Colony-Stimulating Factor Treatment in the Brains of Aged APP/PS1 Mice
inferred← citeshttps://doi.org/10.3390/ijms17122030openalex-snapshot
Checkpoints to the Brain: Directing Myeloid Cell Migration to the Central Nervous System
inferred← citeshttps://doi.org/10.3390/ijms18071418openalex-snapshot
Effects of an Inhibitor of Monocyte Recruitment on Recovery from Traumatic Brain Injury in Mice Treated with Granulocyte Colony-Stimulating Factor
inferred← citeshttps://doi.org/10.3390/vaccines8030485openalex-snapshot
The Role of Microglia during West Nile Virus Infection of the Central Nervous System
inferred← citeshttps://doi.org/10.3727/096368916x691114openalex-snapshot
Transient Microneedle Insertion into Hippocampus Triggers Neurogenesis and Decreases Amyloid Burden in a Mouse Model of Alzheimer's Disease
inferred← citeshttps://doi.org/10.4103/1673-5374.198980openalex-snapshot
Insights into the protective role of immunity in neurodegenerative disease
inferred← citeshttps://doi.org/10.4172/2167-7182.1000104openalex-snapshot
Rheumatoid Arthritis and Alzheimer Disease: Possible Cellular and Molecular Links
inferred← citeshttps://doi.org/10.4172/bdt.1000101openalex-snapshot
Granulocyte Macrophage Colony Stimulating Factor Treatment is Associated with Improved Cognition in Cancer Patients
inferred← citeshttps://doi.org/10.70675/4560bf49z9fd2z42a9z83e6zdd4b8e4e87eaopenalex-snapshot
Recherche de facteurs associés à la maladie d’Alzheimer par réutilisation de base de données massives
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