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The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Analysis and Interpretation of Treatment Effects in Subgroups of Patients in Randomized Clinical Trials
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Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
inferredcites →https://doi.org/10.1002/14651858.cd001886.pub3openalex-snapshot
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
inferredcites →https://doi.org/10.1002/14651858.cd001886.pub4openalex-snapshot
Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion
inferredcites →https://doi.org/10.1002/14651858.cd004896openalex-snapshot
Anti-fibrinolytic drugs for acute traumatic injury
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Causes of death following multiple trauma
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Disseminated intravascular coagulation with a fibrinolytic phenotype at an early phase of trauma predicts mortality
inferredcites →https://doi.org/10.1016/s0003-4975(99)00866-8openalex-snapshot
Hemostatic effects of aprotinin, tranexamic acid and ϵ-aminocaproic acid in primary cardiac surgery
inferredcites →https://doi.org/10.1016/s0140-6736openalex-snapshot
Correspondence - Tranexamic acid for traumatic brain injury
inferredcites →https://doi.org/10.1016/s0140-6736(00)02039-0openalex-snapshot
Subgroup analysis and other (mis)uses of baseline data in clinical trials
inferredcites →https://doi.org/10.1016/s0140-6736(03)12195-2openalex-snapshot
Transfusion medicine: looking to the future
inferredcites →https://doi.org/10.1016/s0140-6736(04)17188-2openalex-snapshot
Effect of intravenous corticosteroids on death within 14 days in 10 008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial
inferredcites →https://doi.org/10.1016/s0140-6736(10)60835-5openalex-snapshot
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
inferredcites →https://doi.org/10.1016/s0140-6736(10)60939-7openalex-snapshot
Antifibrinolytic therapy: new data and new concepts
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The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial
inferredcites →https://doi.org/10.1016/s0140-6736(99)05155-7openalex-snapshot
Treatment of traumatic bleeding with recombinant factor VIIa
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The problem of transfusion-associated acquired immunodeficiency syndrome in Africa: A quantitative approach
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Meta-analysis of systemic anti-fibrinolytics in traumatic hyphaema
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Macroeconomics and Health: Investing in Health for Economic Development
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Challenges for providing effective hemostasis in surgery and trauma
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Systematic Underestimation of Treatment Effects as a Result of Diagnostic Test Inaccuracy: Implications for the Interpretation and Design of Thromboprophylaxis Trials
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Equity dimensions of road traffic injuries in low- and middle-income countries
inferredcites →https://doi.org/10.1097/00000539-200105000-00010openalex-snapshot
Plasma Tranexamic Acid Concentrations During Cardiopulmonary Bypass
inferredcites →https://doi.org/10.1097/00000542-199502000-00009openalex-snapshot
The Dose-Response Relationship of Tranexamic Acid
inferredcites →https://doi.org/10.1097/00002030-200401230-00032openalex-snapshot
The incidence of HIV-1 associated with injections and transfusions in a prospective cohort, Rakai, Uganda
inferredcites →https://doi.org/10.1097/00005373-199502000-00006openalex-snapshot
Epidemiology of Trauma Deaths
inferredcites →https://doi.org/10.1097/ta.0b013e318169cd3copenalex-snapshot
Acute Coagulopathy of Trauma: Hypoperfusion Induces Systemic Anticoagulation and Hyperfibrinolysis
inferredcites →https://doi.org/10.1097/ta.0b013e3181877a9copenalex-snapshot
The Coagulopathy of Trauma: A Review of Mechanisms
inferredcites →https://doi.org/10.1136/ard.61.suppl_2.ii92openalex-snapshot
The National Institute for Clinical Excellence (NICE)
inferredcites →https://doi.org/10.1136/bmj.38875.757488.4fopenalex-snapshot
Deaths from injury in children and employment status in family: analysis of trends in class specific death rates
inferredcites →https://doi.org/10.1136/bmj.39140.623137.beopenalex-snapshot
Towards sustainable clinical trials
inferredcites →https://doi.org/10.1136/bmj.b2393openalex-snapshot
Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls
inferredcites →https://doi.org/10.1136/bmj.c117openalex-snapshot
Is a subgroup effect believable? Updating criteria to evaluate the credibility of subgroup analyses
inferredcites →https://doi.org/10.1136/emj.2002.004788openalex-snapshot
Research in emergency situations: with or without relatives consent
inferredcites →https://doi.org/10.1136/jcp.33.suppl_14.35openalex-snapshot
Basis of antifibrinolytic therapy
inferredcites →https://doi.org/10.1136/jcp.s3-14.1.35openalex-snapshot
Basis of antifibrinolytic therapy
inferredcites →https://doi.org/10.1177/1740774507087704openalex-snapshot
Specific barriers to the conduct of randomized trials
inferredcites →https://doi.org/10.1186/1471-2288-8-72openalex-snapshot
Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury
inferredcites →https://doi.org/10.1186/1471-2393-9-29openalex-snapshot
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review
inferredcites →https://doi.org/10.1186/1745-6215-11-40openalex-snapshot
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial
inferredcites →https://doi.org/10.1186/1745-6215-12-31openalex-snapshot
Reducing the environmental impact of trials: a comparison of the carbon footprint of the CRASH-1 and CRASH-2 clinical trials
inferredcites →https://doi.org/10.1213/ane.0b013e3181679555openalex-snapshot
Antifibrinolytic Therapy in Surgery for Congenital Heart Disease
inferredcites →https://doi.org/10.1371/journal.pone.0018987openalex-snapshot
Cost-Effectiveness Analysis of Administering Tranexamic Acid to Bleeding Trauma Patients Using Evidence from the CRASH-2 Trial
inferredcites →https://doi.org/10.1515/jibl.2009.12openalex-snapshot
Declaration of Helsinki Ethical Principles for Medical Research Involving Human Subjects
inferredcites →https://doi.org/10.1590/s1020-49892002000800017openalex-snapshot
Macroeconomics and health: investing in health for economic development
inferredcites →https://doi.org/10.1590/s1516-31802011000500014openalex-snapshot
Antifibrinolytic drugs for acute traumatic injury
inferredcites →https://doi.org/10.2165/00003495-200262150-00003openalex-snapshot
Pharmacological Strategies to Decrease Transfusion Requirements in Patients Undergoing Surgery
inferredcites →https://doi.org/10.2165/00124363-200721060-00004openalex-snapshot
Regulation of Therapeutic Research is Compromising the Interests of Patients1
inferredcites →https://doi.org/10.3310/hta16130openalex-snapshot
CRASH-2 (Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage) intracranial bleeding study: the effect of tranexamic acid in traumatic brain injury, a nested randomised, placebo-controlled trial.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.5137566openalex-extracted
Randomized, Controlled Trial of Tranexamic Acid on Blood Coagulation in Primary Total Hip Arthroplasty Using Rotational Thromboelastometry
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Tranexamic Acid and Blood Transfusion in Liver Resection—Reply
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Bayesian Statistics to Reanalyze Data From the STAAMP Trial
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Does Tranexamic Acid Cause Venous Thromboembolism After Trauma?
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Tranexamic Acid in General Surgery—Who Benefits the Most?
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Tranexamic acid for patients with nasal haemorrhage (epistaxis)
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Blood transfusion strategies for major bleeding in trauma
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Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery
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Tranexamic acid for the reduction of bleeding during functional endoscopic sinus surgery
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Antifibrinolytic drugs for treating primary postpartum haemorrhage
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Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis
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Pharmacological interventions for the prevention of bleeding in people undergoing elective hip or knee surgery: a systematic review and network meta-analysis
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Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation of hip, pelvic and long bone fractures: a systematic review and network meta-analysis
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Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for hip, pelvic and long bone fractures
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Pharmacological interventions for the treatment of bleeding in people treated for blunt force or penetrating injury in an emergency department: a systematic review and network meta-analysis
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Acquired Coagulation Disorders
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Treatment of individuals who cannot receive blood products for religious or other reasons
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Tranexamic acid in endoscopic sinus and skull base surgery: A systematic review and meta‐analysis
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Bad blood: A coagulopathy associated with trauma and massive transfusion review
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Recognition to repair: Managing reservoir complications in inflatable penile prosthesis surgery
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Non‐coagulopathic hemothorax in a dog: A case report
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Viscoelastic Testing for Coagulation Management in Vascular Surgery—A Narrative Review
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Instant clot forming and antibacterial wound dressings: Achieving hemostasis in trauma injuries with S‐ nitroso ‐N ‐acetylpenicillamine—tranexamic acid—propolis formulation
inferred← citeshttps://doi.org/10.1002/jha2.699openalex-snapshot
Prophylaxis with low dose tranexamic acid in acute myeloid leukemia patients undergoing intensive chemotherapy
inferred← citeshttps://doi.org/10.1002/lary.70933openalex-snapshot
Impact of Tranexamic Acid on Head and Neck Free Flap Outcomes: A Retrospective Cohort Analysis
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Recent Advances on Plasmin Inhibitors for the Treatment of Fibrinolysis‐Related Disorders
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Reducing Surgery for Pediatric Posttonsillectomy Hemorrhage Using Tranexamic Acid: A Quality Improvement Initiative
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Successful management of refractory bleeding in liver failure with tranexamic acid: Case report and literature review
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Computed tomographic features of presumed craniodorsal mediastinal haematoma and thoracic periaortitis secondary to spirocercosis in a dog
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Intravenous Haemostatic Adjuncts
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Traumatic Brain Injury (TBI): Current Diagnostic and Therapeutic Challenges
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Pharmacological Neuroprotection
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The Role of Blood Products in Damage Control Resuscitation in Explosion-Related Trauma
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Fibrinolysis Shutdown and Venous Thromboembolism
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Traumatic Brain Injury-Induced Coagulopathy
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Massive Transfusion Protocol
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Blood Transfusion in the Severe Trauma Patient
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Blood Transfusion and Traumatic Brain Injury
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Nonsurgical Treatment of Chronic Subdural Hematoma
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Haemostasis and Coagulopathy
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The Population at Risk Predictors of MOF
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Volume and Blood Management
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Resuscitation of Traumatic Hemorrhagic Shock
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Coagulation and Thrombosis
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Hematology/Blood Products
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Hematologic Changes with Aging
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Thromboembolism and Bleeding
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Out-of-Hospital Management of Traumatic Brain Injury
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Fluid Management and Hyperosmolar Therapy in Neurotrauma
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Thrombolytics and Antifibrinolytics
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Therapeutic Principles of Bleeding Disorders
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Hemorrhagic Shock in Children
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Approach to Thrombocytopenia in the ICU
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Anticoagulation in the Intensive Care Unit
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Rational and Timely Use of Coagulation Factor Concentrates in Massive Bleeding Without Point-of-Care Coagulation Monitoring
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Massive Transfusion Protocols
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Thromboembolism and Bleeding
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Thromboembolism and Bleeding
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Perioperative Considerations for Surgical Emergencies
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Soft-Tissue Reconstructive Considerations in the Damage Control Environment
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Thromboembolism and Bleeding
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Prehospital Care and Transport
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Prehospital Care and Transport
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Leitlinien zur Verwundetenversorgung
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Blood Transfusion in Neurosurgery
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Burn- and Trauma-Associated Pulmonary Infection
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Neurological Complications of Anticoagulation
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Benefits of the tranexamic acid in head trauma with no extracranial bleeding: a prospective follow-up of 180 patients
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Do not drink and lyse: alcohol intoxication increases fibrinolysis shutdown in injured patients
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CRASH 3: a monumental effort with minimal gain
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Systemic hemostatic agents initiated in trauma patients in the pre-hospital setting: a systematic review
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Application and observation of hemostatic effect of independently developed hemostatic equipment in a lethal swine exsanguination model
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Effectiveness of prophylactic pharmacological hemostatic agents for reduction of blood loss at vaginal surgery: a systematic review and meta-analysis
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Tranexamic acid reduces postoperative blood loss in lipedema patients undergoing large-volume power-assisted liposuction
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Intravenous tranexamic acid use in breast reconstruction: a retrospective study at a high-volume breast center
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Tranexamic acid with a pre-operative suspension of anticoagulation decreases operative time and blood transfusion in the treatment of pelvic and acetabulum fractures
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Efficacy of Topical Tranexamic Acid (Cyclokapron) in “Wet” Field Infiltration with Dilute Local Anaesthetic Solutions in Plastic Surgery
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The Use of Tranexamic Acid in Liposuction for Lipedema: A Retrospective Study on 230 Procedures
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Pilot Study of Combined Tranexamic Acid Therapy in Breast Reduction – Intravenous and Local Infiltration
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Invited Commentary: A Decade Older Polytrauma Patients Do As Well Without As the Younger Ones with Tranexamic Acid
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Safety and Efficacy of Tranexamic Acid to Minimise Perioperative Bleeding in Hepatic Surgery: A Systematic Review and Meta‐Analysis
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Postoperative pain evaluation in laparoscopic radical prostatectomy surgery using tranexamic acid: analgesia?, hyperalgesia??
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Tranexamic acid in radical cystectomy: a systematic review and meta-analysis of efficacy and safety
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Perioperative management of acetabular and pelvic fractures: evidence-based recommendations
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A breath of fresh air: an updated review of nebulised tranexamic acid for post-tonsillectomy haemorrhage
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An update on paediatric traumatic brain injury in the emergency department: a narrative review
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Peroperative administration of tranexamic acid in sleeve gastrectomy to reduce hemorrhage: a double-blind randomized controlled trial
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Feasibility of a standardized three-dose intravenous tranexamic acid protocol in bariatric surgery: a pilot study
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Effect of intraoperative tranexamic acid on blood loss and outcomes in intertrochanteric fractures: a retrospective study of 1728 patients
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Hemostatic disturbances in traumatic brain injury: from mechanism to management
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Intracranial hypertension in patients with aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis
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Tranexamic acid in Neurosurgery: a controversy indication—review
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Computational Model for Hyperfibrinolytic Onset of Acute Traumatic Coagulopathy
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Possible effect of the early administration of tranexamic acid on myocardial injury in patients with severe trauma
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Ghrelin may protect against vascular endothelial injury in Acute traumatic coagulopathy by mediating the RhoA/ROCK/MLC2 pathway
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Reply to “Bleeding in Sleeve Gastrectomy—A Simple and Cost-Effective Solution”
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The Effect of Preoperative Single-Dose Tranexamic Acid on Bleeding and Thromboembolic Events Following Bariatric Surgery
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Tranexamic acid in emergency medicine. An overview of reviews
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Is there a role for antifibrinolytics in pelvic and acetabular fracture surgery?
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A systematic review and meta-analysis assessing the use of tranexamic acid (TXA) in acute gastrointestinal bleeding
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Impact of Recent Studies for the Treatment of Intracerebral Hemorrhage
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The Utility of Tranexamic Acid in Endoscopic Surgeries for Benign Prostatic Hyperplasia
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Thromboelastography is a Marker for Clinically Significant Progressive Hemorrhagic Injury in Severe Traumatic Brain Injury
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The efficacy of prophylactic tranexamic acid in patients with hematologic malignancy: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1007/s12306-024-00826-0openalex-snapshot
Role of tranexamic acid in reducing peri-operative blood loss in open spine surgeries
inferred← citeshttps://doi.org/10.1007/s13181-024-00989-zopenalex-snapshot
Toxicity Following Tranexamic Acid Overdose
inferred← citeshttps://doi.org/10.1007/s13341-015-0540-9openalex-snapshot
Actualités en médecine d’urgence
inferred← citeshttps://doi.org/10.1007/s13341-016-0606-3openalex-snapshot
Retour d’expérience des attentats du 13 novembre 2015. Rôle spécifique des hôpitaux de proximité
inferred← citeshttps://doi.org/10.1007/s40137-015-0092-3openalex-snapshot
Massive Transfusion Protocols in the Pediatric Trauma Patient: An Update
inferred← citeshttps://doi.org/10.1007/s40140-016-0150-0openalex-snapshot
Anesthetic Management of the Burn Patient
inferred← citeshttps://doi.org/10.1007/s40140-020-00397-3openalex-snapshot
Is Fresh Frozen Plasma Still Necessary for Management of Acute Traumatic Coagulopathy?
inferred← citeshttps://doi.org/10.1007/s40140-021-00444-7openalex-snapshot
Pharmacologic Prevention and Treatment of Postpartum Hemorrhage
inferred← citeshttps://doi.org/10.1007/s40140-021-00509-7openalex-snapshot
The Use of Tranexamic Acid in Trauma
inferred← citeshttps://doi.org/10.1007/s40140-023-00567-zopenalex-snapshot
Antifibrinolytics as a Patient Blood Management Modality in Craniosynostosis Surgery: Current Concepts and a View to the Future
inferred← citeshttps://doi.org/10.1007/s40140-024-00681-6openalex-snapshot
The Role of Selected Adjuncts in the Management of the Bleeding Trauma Patient: Calcium and Vasopressin
inferred← citeshttps://doi.org/10.1007/s40263-025-01173-9openalex-snapshot
Update on Neuroprotection after Traumatic Brain Injury
inferred← citeshttps://doi.org/10.1007/s40719-024-00266-yopenalex-snapshot
Massive Transfusion Protocols in Pediatric Trauma
inferred← citeshttps://doi.org/10.1016/b978-0-08-102723-3.00036-6openalex-snapshot
Symptomatic and Supportive Care
inferred← citeshttps://doi.org/10.1016/b978-0-12-813596-9.00007-9openalex-snapshot
Potential Neuroprotective Strategies for Traumatic Brain Injury
inferred← citeshttps://doi.org/10.1016/b978-0-12-821711-5.00006-1openalex-snapshot
Molecular aspects of regeneration and neuroprotection in neurotraumatic diseases
inferred← citeshttps://doi.org/10.1016/b978-0-323-46202-0.00028-5openalex-snapshot
Blood Component and Pharmacologic Therapy for Hemostatic Disorders
inferred← citeshttps://doi.org/10.1016/b978-0-323-47661-4.00022-8openalex-snapshot
Hematology, Hemostasis, Thromboprophylaxis, and Transfusion Medicine in Burn Patients
inferred← citeshttps://doi.org/10.1016/b978-0-323-76469-8.00114-3openalex-snapshot
Management of the bleeding patient in the ICU
inferred← citeshttps://doi.org/10.1016/b978-0-443-11611-7.00112-2openalex-snapshot
Blood transfusion and patient blood management
inferred← citeshttps://doi.org/10.1016/b978-0-443-21707-4.00042-2openalex-snapshot
Peripartum hemorrhage and management
inferred← citeshttps://doi.org/10.1016/b978-1-4557-2296-9.00027-0openalex-snapshot
Blood Component and Pharmacologic Therapy for Hemostatic Disorders
inferred← citeshttps://doi.org/10.1016/b978-3-437-15102-6.00037-9openalex-snapshot
Herz-Kreislauf-Stillstand im alpinen Gelände
inferred← citeshttps://doi.org/10.1016/b978-3-437-23671-6.00003-1openalex-snapshot
Herz-Kreislauf-System
inferred← citeshttps://doi.org/10.1016/b978-3-437-23672-3.00003-2openalex-snapshot
Herz-Kreislauf-System
inferred← citeshttps://doi.org/10.1016/b978-3-437-23673-0.00003-3openalex-snapshot
Herz-Kreislauf-System
inferred← citeshttps://doi.org/10.1016/j.aan.2018.07.001openalex-snapshot
Care of the Severely Injured Orthopedic Trauma Patient
inferred← citeshttps://doi.org/10.1016/j.ab.2024.115714openalex-snapshot
Development of an assay to quantify tranexamic acid levels in plasma
inferred← citeshttps://doi.org/10.1016/j.ajem.2017.08.024openalex-snapshot
Battlefield to bedside: Translating wartime innovations to civilian Emergency Medicine
inferred← citeshttps://doi.org/10.1016/j.ajem.2018.03.033openalex-snapshot
Efficacy of prehospital administration of tranexamic acid in trauma patients: A meta-analysis of the randomized controlled trials
inferred← citeshttps://doi.org/10.1016/j.ajem.2019.04.051openalex-snapshot
Prehospital administration of tranexamic acid in trauma patients: A 1:1 matched comparative study from a level 1 trauma center
inferred← citeshttps://doi.org/10.1016/j.ajem.2019.158499openalex-snapshot
The efficacy of tranexamic acid for brain injury: A meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1016/j.ajem.2020.07.041openalex-snapshot
Massive transfusion protocol in adult trauma population
inferred← citeshttps://doi.org/10.1016/j.ajem.2020.08.062openalex-snapshot
Tranexamic acid for gastrointestinal bleeding: A systematic review with meta-analysis of randomized clinical trials
inferred← citeshttps://doi.org/10.1016/j.ajem.2020.12.013openalex-snapshot
Is the use of greater than 1 L of intravenous crystalloids associated with worse outcomes in trauma patients?
inferred← citeshttps://doi.org/10.1016/j.ajem.2022.01.069openalex-snapshot
Effectiveness and safety of tranexamic acid in pediatric trauma: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.ajem.2023.02.015openalex-snapshot
Rapid administration of Kcentra® during cardiopulmonary arrest
inferred← citeshttps://doi.org/10.1016/j.ajem.2024.12.004openalex-snapshot
Pharmacotherapy adjuncts for traumatic brain injury: A narrative review of evidence and considerations in the emergency department
inferred← citeshttps://doi.org/10.1016/j.ajem.2026.03.021openalex-snapshot
Practice changing articles: Early restrictive versus liberal oxygen for trauma patients
inferred← citeshttps://doi.org/10.1016/j.ajem.2026.09.049openalex-snapshot
Trends in tranexamic acid use in adult emergency departments: a 10-year multi-institutional analysis from Epic Cosmos
inferred← citeshttps://doi.org/10.1016/j.ajog.2016.01.184openalex-snapshot
Anti-hemorrhagic effect of prophylactic tranexamic acid in benign hysterectomy—a double-blinded randomized placebo-controlled trial
inferred← citeshttps://doi.org/10.1016/j.ajogmf.2024.101450openalex-snapshot
Tranexamic acid in preventing postpartum blood loss in vaginal delivery: a double-blinded randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.amj.2017.05.003openalex-snapshot
Logistical Concerns for Prehospital Blood Product Use by Air Medical Services
inferred← citeshttps://doi.org/10.1016/j.amj.2022.06.003openalex-snapshot
Prehospital Ultrasound Use to Guide Resuscitative Thoracotomy in Blunt Traumatic Cardiac Arrest
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2014.09.002openalex-snapshot
Pelvic ring fractures: has mortality improved following the implementation of damage control resuscitation?
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2023.07.040openalex-snapshot
The proteomic and metabolomic signatures of isolated and polytrauma traumatic brain injury
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2023.08.001openalex-snapshot
Temporal changes in the prehospital management of trauma patients: 2014–2021
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2024.115931openalex-snapshot
TXA combined with whole blood transfusion in trauma patients does not increase the risk of VTE but shock index does
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2025.116476openalex-snapshot
Change in novel plasmin activated clotting time assay predicts hyperfibrinolysis, massive transfusion, and mortality in trauma in under 3 minutes
inferred← citeshttps://doi.org/10.1016/j.amjsurg.2025.116778openalex-snapshot
A balancing act: Evaluating the impact of a massive transfusion response team on early balanced resuscitation in non-traumatic hemorrhage
inferred← citeshttps://doi.org/10.1016/j.annemergmed.2018.11.018openalex-snapshot
The Effect of Tranexamic Acid on Functional Outcomes: An Exploratory Analysis of the CRASH-2 Randomized Controlled Trial
inferred← citeshttps://doi.org/10.1016/j.annemergmed.2019.01.042openalex-snapshot
Does Oral or Topical Tranexamic Acid Control Bleeding From Epistaxis?
inferred← citeshttps://doi.org/10.1016/j.annemergmed.2020.12.013openalex-snapshot
The Use of Tranexamic Acid to Reduce the Need for Nasal Packing in Epistaxis (NoPAC): Randomized Controlled Trial
inferred← citeshttps://doi.org/10.1016/j.annemergmed.2024.05.026openalex-snapshot
STOP-MSU: Is It Time to STOP-Tranexamic Acid?
inferred← citeshttps://doi.org/10.1016/j.annemergmed.2025.06.609openalex-snapshot
Tranexamic Acid Timing and Mortality Impact After Trauma
inferred← citeshttps://doi.org/10.1016/j.anrea.2018.02.005openalex-snapshot
Prise en charge d’une parturiente atteinte d’un déficit sévère en facteur VII (≤ 5 %)
inferred← citeshttps://doi.org/10.1016/j.anrea.2026.07.004openalex-snapshot
Mettre en place une stratégie de Damage Control à l’arrivée à l’hôpital
inferred← citeshttps://doi.org/10.1016/j.arth.2015.08.025openalex-snapshot
Minimizing Blood Transfusion in Total Hip and Knee Arthroplasty Through a Multimodal Approach
inferred← citeshttps://doi.org/10.1016/j.bios.2022.114299openalex-snapshot
Assessment of fibrinolytic status in whole blood using a dielectric coagulometry microsensor
inferred← citeshttps://doi.org/10.1016/j.bja.2025.07.092openalex-snapshot
A novel role for ADAMTS13 in hyperfibrinolysis after trauma-induced shock☆
inferred← citeshttps://doi.org/10.1016/j.bja.2026.05.006openalex-snapshot
Coagulopathy in obstetric bleeding: a narrative review and comparison with trauma-induced coagulopathy
inferred← citeshttps://doi.org/10.1016/j.bjae.2024.09.005openalex-snapshot
Anaesthetic management of abdominal trauma
inferred← citeshttps://doi.org/10.1016/j.bjane.2022.08.002openalex-snapshot
Analysis of the efficacy of prophylactic tranexamic acid in preventing postpartum bleeding: systematic review with meta-analysis of randomized clinical trials
inferred← citeshttps://doi.org/10.1016/j.bjane.2024.844562openalex-snapshot
The debate on antifibrinolytics in liver transplantation: always, never, or sometimes?
inferred← citeshttps://doi.org/10.1016/j.bjane.2025.844719openalex-snapshot
Perioperative tranexamic acid in burn surgery: systematic review and meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1016/j.bjps.2025.03.022openalex-snapshot
The current state of tranexamic acid in mastectomy and breast reconstruction: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.blre.2026.101394openalex-snapshot
Supportive strategies in thrombocytopenia: Platelet transfusion and beyond
inferred← citeshttps://doi.org/10.1016/j.bpa.2020.04.005openalex-snapshot
Managing preoperative anemia: Evolving concepts and strategies for improving patient outcomes
inferred← citeshttps://doi.org/10.1016/j.bpa.2026.07.004openalex-snapshot
Transfusion management in critically ill patients
inferred← citeshttps://doi.org/10.1016/j.bpg.2019.02.002openalex-snapshot
The optimal use of blood components in the management of gastrointestinal bleeding
inferred← citeshttps://doi.org/10.1016/j.burns.2023.05.009openalex-snapshot
Tranexamic acid in burn surgery: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.burns.2024.09.009openalex-snapshot
Effects of intravenous tranexamic acid on bleeding during burn surgery: A double-blinded randomized clinical trial
inferred← citeshttps://doi.org/10.1016/j.cbpc.2015.09.009openalex-snapshot
Purification and characterization of tenerplasminin-1, a serine peptidase inhibitor with antiplasmin activity from the coral snake ( Micrurus tener tener ) venom
inferred← citeshttps://doi.org/10.1016/j.ccc.2016.08.004openalex-snapshot
Tranexamic Acid Update in Trauma
inferred← citeshttps://doi.org/10.1016/j.ccc.2017.12.005openalex-snapshot
Blood Product Administration in the Critical Care and Perioperative Settings
inferred← citeshttps://doi.org/10.1016/j.chest.2019.02.010openalex-snapshot
Antifibrinolytic Agents for Hemoptysis Management in Adults With Cystic Fibrosis
inferred← citeshttps://doi.org/10.1016/j.chest.2024.05.021openalex-snapshot
Tranexamic Acid Neurotoxicity After Nebulization and BAL
inferred← citeshttps://doi.org/10.1016/j.clbc.2025.01.011openalex-snapshot
Tranexamic Acid in Breast Surgery – A Systematic Review and Meta-Analysis
inferred← citeshttps://doi.org/10.1016/j.cnc.2023.02.011openalex-snapshot
Management of Intra-abdominal Traumatic Injury
inferred← citeshttps://doi.org/10.1016/j.eclinm.2025.103374openalex-snapshot
The effect of tranexamic acid on blood coagulation in primary total hip arthroplasty using rotational thromboelastometry: a randomized controlled trial
inferred← citeshttps://doi.org/10.1016/j.ejso.2021.05.006openalex-snapshot
Oncoplastic breast surgery: A guide to good practice
inferred← citeshttps://doi.org/10.1016/j.emc.2014.12.006openalex-snapshot
Emergency Department Evaluation and Treatment of Acute Hip and Thigh Pain
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