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Recent Advances in Anti-virulence Therapeutic Strategies With a Focus on Dismantling Bacterial Membrane Microdomains, Toxin Neutralization, Quorum-Sensing Interference and Biofilm Inhibition

https://doi.org/10.3389/fcimb.2019.00074

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Microevolution of Pseudomonas aeruginosa to a Chronic Pathogen of the Cystic Fibrosis Lung

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Exploration of Modulated Genetic Circuits Governing Virulence Determinants in Staphylococcus aureus

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Potential Emergence of Multi-quorum Sensing Inhibitor Resistant (MQSIR) Bacteria

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The hierarchy quorum sensing network in Pseudomonas aeruginosa

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Host Responses to Biofilm

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Specific inhibitions of annonaceous acetogenins on class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae

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Development of a novel series of non-natural triaryl agonists and antagonists of the Pseudomonas aeruginosa LasR quorum sensing receptor

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Design, synthesis and biological evaluation of 4-(alkyloxy)-6-methyl-2H-pyran-2-one derivatives as quorum sensing inhibitors

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Membrane Microdomain Disassembly Inhibits MRSA Antibiotic Resistance

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Infection Control by Antibody Disruption of Bacterial Quorum Sensing Signaling

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Dioxygenase-Mediated Quenching of Quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

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Structural and Functional Analysis of Bacillus subtilis YisP Reveals a Role of Its Product in Biofilm Production

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Small Molecule Inhibitors of Clostridium difficile Toxin B-Induced Cellular Damage

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Attenuating Staphylococcus aureus Virulence by Targeting Flotillin Protein Scaffold Activity

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Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis

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α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

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Auto Poisoning of the Respiratory Chain by a Quorum-Sensing-Regulated Molecule Favors Biofilm Formation and Antibiotic Tolerance

inferredcites →https://doi.org/10.1016/j.ejmech.2014.02.014openalex-snapshot

Benzamidobenzoic acids as potent PqsD inhibitors for the treatment of Pseudomonas aeruginosa infections

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Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD

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Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa

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Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists

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Zingerone silences quorum sensing and attenuates virulence of Pseudomonas aeruginosa

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Enzymatic dispersal of dual-species biofilms carrying Listeria monocytogenes and other associated food industry bacteria

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Quorum quenching enzymes

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Pseudomonas aeruginosa Biofilm Infections: Community Structure, Antimicrobial Tolerance and Immune Response

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Considerations and caveats in anti-virulence drug development

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Exploring functional membrane microdomains in bacteria: an overview

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Discovery of potent inhibitors targeting Vibrio harveyi LuxR through shape and e-pharmacophore based virtual screening and its biological evaluation

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Inhibition of quorum sensing-controlled biofilm formation in Pseudomonas aeruginosa by quorum-sensing inhibitors

inferredcites →https://doi.org/10.1016/j.micpath.2017.09.043openalex-snapshot

Inhibition of quorum sensing related virulence factors of Pseudomonas aeruginosa by pyridoxal lactohydrazone

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Inhibition of alpha-hemolysin expression by resveratrol attenuates Staphylococcus aureus virulence

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The quorum quenching antibody RS2-1G9 protects macrophages from the cytotoxic effects of the Pseudomonas aeruginosa quorum sensing signalling molecule N-3-oxo-dodecanoyl-homoserine lactone

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New frontiers for anti-biofilm drug development

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Coumarins reduce biofilm formation and the virulence of Escherichia coli O157:H7

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Enzyme targets for drug design of new anti-virulence therapeutics

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Quorum-Sensing Systems as Targets for Antivirulence Therapy

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Host–pathogen interactions in sepsis

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Truncated Autoinducing Peptides as Antagonists ofStaphylococcus lugdunensisQuorum Sensing

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Quorum-Quenching and Matrix-Degrading Enzymes in Multilayer Coatings Synergistically Prevent Bacterial Biofilm Formation on Urinary Catheters

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Development of Molecularly Imprinted Polymers To Block Quorum Sensing and Inhibit Bacterial Biofilm Formation

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Biosynthesis of Squalene from Farnesyl Diphosphate in Bacteria: Three Steps Catalyzed by Three Enzymes

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Application of Dual Inhibition Concept within Looped Autoregulatory Systems toward Antivirulence Agents against Pseudomonas aeruginosa Infections

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Designed Small-Molecule Inhibitors of the Anthranilyl-CoA Synthetase PqsA Block Quinolone Biosynthesis in Pseudomonas aeruginosa

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Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance

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Structure-Based Design and Biological Evaluation of Triphenyl Scaffold-Based Hybrid Compounds as Hydrolytically Stable Modulators of a LuxR-Type Quorum Sensing Receptor

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Pseudomonas aeruginosa LasR·DNA Binding Is Directly Inhibited by Quorum Sensing Antagonists

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Receptor-Based Peptides for Inhibition of Leukotoxin Activity

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The Increasingly Complex Mechanism of HMG-CoA Reductase

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Passive Control of Quorum Sensing: Prevention of Pseudomonas aeruginosa Biofilm Formation by Imprinted Polymers

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Attenuation of Vibrio fischeri Quorum Sensing Using Rationally Designed Polymers

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Cross Species Quorum Quenching Using a Native AI-2 Processing Enzyme

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Structure-Based Design and Screen of Novel Inhibitors for Class II 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase from Streptococcus Pneumoniae

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Mechanisms and Synthetic Modulators of AHL-Dependent Gene Regulation

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Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

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Small Molecule Disruption of Quorum Sensing Cross-Regulation in Pseudomonas aeruginosa Causes Major and Unexpected Alterations to Virulence Phenotypes

inferredcites →https://doi.org/10.1021/jm991031bopenalex-snapshot

Solution Structure of Polymyxins B and E and Effect of Binding to Lipopolysaccharide: An NMR and Molecular Modeling Study

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Antimicrobial peptides of multicellular organisms

inferredcites →https://doi.org/10.1038/ismej.2011.122openalex-snapshot

Quorum quenching quandary: resistance to antivirulence compounds

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Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases

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Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice

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Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

inferredcites →https://doi.org/10.1038/nchembio.153openalex-snapshot

Transition state analogs of 5′-methylthioadenosine nucleosidase disrupt quorum sensing

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Targeting virulence: a new paradigm for antimicrobial therapy

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Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

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Poring over pores: α-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia

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Plasmid transfer in biofilms: a perspective on limitations and opportunities

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Lovastatin and beyond: the history of the HMG-CoA reductase inhibitors

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Quorum sensing signal–response systems in Gram-negative bacteria

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Biofilms: an emergent form of bacterial life

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Subinhibitory concentrations of resveratrol reduce alpha-hemolysin production in Staphylococcus aureus isolates by downregulating saeRS

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Release of Staphylococcus aureus extracellular vesicles and their application as a vaccine platform

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VLP-based vaccine induces immune control of Staphylococcus aureus virulence regulation

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Combination Therapy Strategy of Quorum Quenching Enzyme and Quorum Sensing Inhibitor in Suppressing Multiple Quorum Sensing Pathways of P. aeruginosa

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Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

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Terrein is an inhibitor of quorum sensing and c-di-GMP in Pseudomonas aeruginosa: a connection between quorum sensing and c-di-GMP

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Structural and Biochemical Characterization of AaL, a Quorum Quenching Lactonase with Unusual Kinetic Properties

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Small-molecule AgrA inhibitors F12 and F19 act as antivirulence agents against Gram-positive pathogens

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Mechanistic analysis of a synthetic inhibitor of the Pseudomonas aeruginosa LasI quorum-sensing signal synthase

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Discovery of new diketopiperazines inhibiting Burkholderia cenocepacia quorum sensing in vitro and in vivo

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Synthesis and stability of small molecule probes for Pseudomonas aeruginosa quorum sensing modulation

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Hybrids of acylated homoserine lactone and nitric oxide donors as inhibitors of quorum sensing and virulence factors in Pseudomonas aeruginosa

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5-Benzylidene-4-oxazolidinones potently inhibit biofilm formation in Methicillin-resistant Staphylococcus aureus

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2-Aminobenzimidazoles as antibiofilm agents against Salmonella enterica serovar Typhimurium

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Proceedings of the Chemical Society. January 1963

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Retrocyclins neutralize bacterial toxins by potentiating their unfolding

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Dispersing biofilms with engineered enzymatic bacteriophage

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Mechanism of action and inhibition of dehydrosqualene synthase

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A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

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Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa

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Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent.

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NMR Structures and Interactions of Temporin-1Tl and Temporin-1Tb with Lipopolysaccharide Micelles

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PqsBC, a Condensing Enzyme in the Biosynthesis of the Pseudomonas aeruginosa Quinolone Signal

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Flavonoids Suppress Pseudomonas aeruginosa Virulence through Allosteric Inhibition of Quorum-sensing Receptors

inferredcites →https://doi.org/10.1074/jbc.m213006200openalex-snapshot

Crystal Structure of a Statin Bound to a Class II Hydroxymethylglutaryl-CoA Reductase

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What's on the Outside Matters: The Role of the Extracellular Polymeric Substance of Gram-negative Biofilms in Evading Host Immunity and as a Target for Therapeutic Intervention

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Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin ofStaphylococcus aureusfor the generation of neutralizing antibodies

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Regulation ofStaphylococcus aureusα‐Toxin Gene(hla)Expression byagr, sarA,andsaeIn Vitro and in Experimental Infective Endocarditis

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Beyond killing

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High variability in quorum quenching and growth inhibition by furanone C-30 in Pseudomonas aeruginosa clinical isolates from cystic fibrosis patients

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Quorum quenching: role in nature and applied developments

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Molecular mechanisms of biofilm-based antibiotic resistance and tolerance in pathogenic bacteria

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Application of an agr-Specific Antivirulence Compound as Therapy for Staphylococcus aureus-Induced Inflammatory Skin Disease

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Nosocomial outbreak of carbapenem-resistant Enterobacter cloacae highlighting the interspecies transferability of the blaOXA-48 gene in the gut flora

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aBiofilm: a resource of anti-biofilm agents and their potential implications in targeting antibiotic drug resistance

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A Theobromine-Derived Anticancer Compound with Potent Activity Against Acinetobacter baumannii: In Vitro and In Silico Investigations

inferred← citeshttps://doi.org/10.1016/j.msec.2021.112592openalex-snapshot

Biofilm inhibition in Candida albicans with biogenic hierarchical zinc-oxide nanoparticles

inferred← citeshttps://doi.org/10.1016/j.nantod.2021.101368openalex-snapshot

Microalgae-based bioactive hydrogel loaded with quorum sensing inhibitor promotes infected wound healing

inferred← citeshttps://doi.org/10.1016/j.nxbio.2025.100003openalex-snapshot

Emerging technologies and innovative approaches to combat antimicrobial resistance: A narrative review of next-generation therapeutic strategies

inferred← citeshttps://doi.org/10.1016/j.phymed.2026.158260openalex-snapshot

Anti-quorum-sensing activity of Plectranthus aliciae in multispecies Cutibacterium acnes-Staphylococcus epidermidis systems

inferred← citeshttps://doi.org/10.1016/j.redox.2026.104340openalex-snapshot

S-Nitrosothiols modulate Porphyromonas gingivalis virulence

inferred← citeshttps://doi.org/10.1016/j.resmic.2022.103985openalex-snapshot

Biochemical and molecular mechanisms of antibiotic resistance in Salmonella spp.

inferred← citeshttps://doi.org/10.1016/j.rineng.2026.113447openalex-snapshot

SMP103: a de novo-engineered macrocyclic peptide binder candidate targeting the virulence-associated transpeptidase Sortase A

inferred← citeshttps://doi.org/10.1016/j.rvsc.2026.106355openalex-snapshot

Nonliving biotherapeutics for veterinary enteric disease: Postbiotics, bacteriophage, and antivirulence strategies to reduce antibiotic dependence

inferred← citeshttps://doi.org/10.1016/j.surfcoat.2021.126981openalex-snapshot

Anti-biofilm activity and in vitro biocompatibility of copper surface prepared by cold gas spray

inferred← citeshttps://doi.org/10.1016/j.vetmic.2021.109073openalex-snapshot

Biofilm characteristics and transcriptomic analysis of Haemophilus parasuis

inferred← citeshttps://doi.org/10.1016/j.ygeno.2020.09.039openalex-snapshot

Microbiome dynamics and genomic determinants of bovine mastitis

inferred← citeshttps://doi.org/10.1016/s0140-6736(24)02081-6openalex-snapshot

Multidrug-resistant Gram-negative bacterial infections

inferred← citeshttps://doi.org/10.1021/acs.jafc.2c00532openalex-snapshot

Phloroglucinol and Its Derivatives: Antimicrobial Properties toward Microbial Pathogens

inferred← citeshttps://doi.org/10.1021/acs.jcim.0c01233openalex-snapshot

Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c00973openalex-snapshot

Design, Synthesis, and Evaluation of New 1H-Benzo[d]imidazole Based PqsR Inhibitors as Adjuvant Therapy for Pseudomonas aeruginosa Infections

inferred← citeshttps://doi.org/10.1021/acsami.1c18553openalex-snapshot

Understanding the Photochemical Properties of Polythiophene Polyelectrolyte Soft Aggregates with Sodium Dodecyl Sulfate for Antimicrobial Activity

inferred← citeshttps://doi.org/10.1021/acsinfecdis.5c00542openalex-snapshot

Sulfonyl Homoserine Lactones Are Tunable Probes to Inhibit the Quorum Sensing Receptor RhlR and Reduce Swarming Motility in Pseudomonas aeruginosa

inferred← citeshttps://doi.org/10.1021/acsomega.0c03634openalex-snapshot

Anti-quorum Sensing and Anti-biofilm Activity of Zinc Oxide Nanospikes

inferred← citeshttps://doi.org/10.1021/acsptsci.5c00187openalex-snapshot

Anti-pyocyanin Antibody Exhibits Cytotoxicity Protective Effects on Macrophages: A Promising Innovative Therapeutic Approach for Pseudomonas aeruginosa Infections

inferred← citeshttps://doi.org/10.1038/s41368-023-00245-0openalex-snapshot

Artemisinins inhibit oral candidiasis caused by Candida albicans through the repression on its hyphal development

inferred← citeshttps://doi.org/10.1038/s41427-020-00252-1openalex-snapshot

Selective reaction of conjugated polymers with basic proteins for broad-spectrum antivirulence therapy

inferred← citeshttps://doi.org/10.1038/s41429-022-00587-7openalex-snapshot

New meroterpenoids from a soil-derived fungus Penicillium sp. SSW03M2 GY and their anti-virulence activity

inferred← citeshttps://doi.org/10.1038/s41429-023-00602-5openalex-snapshot

Fluorothiazinon inhibits the virulence factors of uropathogenic Escherichia coli involved in the development of urinary tract infection

inferred← citeshttps://doi.org/10.1038/s41522-021-00258-9openalex-snapshot

Controlled spatial organization of bacterial growth reveals key role of cell filamentation preceding Xylella fastidiosa biofilm formation

inferred← citeshttps://doi.org/10.1038/s41570-021-00313-1openalex-snapshot

Towards the sustainable discovery and development of new antibiotics

inferred← citeshttps://doi.org/10.1038/s41579-019-0288-0openalex-snapshot

The global preclinical antibacterial pipeline

inferred← citeshttps://doi.org/10.1038/s41579-024-01105-2openalex-snapshot

Bloodstream infections: mechanisms of pathogenesis and opportunities for intervention

inferred← citeshttps://doi.org/10.1038/s41589-023-01373-8openalex-snapshot

An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa

inferred← citeshttps://doi.org/10.1038/s41598-021-81007-yopenalex-snapshot

A high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics

inferred← citeshttps://doi.org/10.1038/s41598-021-85100-0openalex-snapshot

Pseudomonas aeruginosa PA80 is a cystic fibrosis isolate deficient in RhlRI quorum sensing

inferred← citeshttps://doi.org/10.1038/s41598-022-24111-xopenalex-snapshot

Influence of tramadol on bacterial burden in the standard neutropenic thigh infection model

inferred← citeshttps://doi.org/10.1038/s41598-024-58973-0openalex-snapshot

Bacillus velezensis iturins inhibit the hemolytic activity of Staphylococcus aureus

inferred← citeshttps://doi.org/10.1038/s41598-026-43638-xopenalex-snapshot

In silico discovery of thioglycoside analogues as donor-site inhibitors of glycosyltransferase LgtC

inferred← citeshttps://doi.org/10.1039/bk9781837671380-00250openalex-snapshot

Quorum Sensing: A New Target for Anti-infective Drug Therapy

inferred← citeshttps://doi.org/10.1039/bk9781837671380-00325openalex-snapshot

Quorum Quenching in Anti-virulence Therapy

inferred← citeshttps://doi.org/10.1039/d0ob01851aopenalex-snapshot

Unusual bridged angucyclinones and potent anticancer compounds from Streptomyces bulli GJA1

inferred← citeshttps://doi.org/10.1039/d1np00053eopenalex-snapshot

Challenges and opportunities for cheat therapy in the control of bacterial infections

inferred← citeshttps://doi.org/10.1039/d2cc05733fopenalex-snapshot

Potent pan-group quorum sensing inhibitors in Staphylococcus aureus revealed by N-terminal tailoring of peptidomimetics

inferred← citeshttps://doi.org/10.1039/d2cp01873jopenalex-snapshot

Simulation study of domain formation in a model bacterial membrane

inferred← citeshttps://doi.org/10.1039/d2sc05369aopenalex-snapshot

Targeting multidrug resistant Staphylococcus infections with bacterial histidine kinase inhibitors

inferred← citeshttps://doi.org/10.1039/d5md00272aopenalex-snapshot

Small molecule antipathogenic agents against Staphylococcus aureus infections

inferred← citeshttps://doi.org/10.1039/d5na00006hopenalex-snapshot

Mucolytic and antibiotic combination therapy using silica-based nanocarriers to eradicate Escherichia coli biofilms

inferred← citeshttps://doi.org/10.1042/bst20250151openalex-snapshot

Insight into the relationship between type IV pilus function and biofilm formation

inferred← citeshttps://doi.org/10.1079/9781789249200.0009openalex-snapshot

Hidden Inside Plants: Potential of Endophytic Microorganisms as Next-generation Biopesticides

inferred← citeshttps://doi.org/10.1080/07391102.2021.2000499openalex-snapshot

Identification and functional annotation of hypothetical proteins of uropathogenic Escherichia coli strain CFT073 towards designing antimicrobial drug targets

inferred← citeshttps://doi.org/10.1080/07391102.2022.2093274openalex-snapshot

Paracoccidioides brasiliensis plasma membrane characterization by EPR spectroscopy and interactions with amphotericin B, miltefosine and nerolidol

inferred← citeshttps://doi.org/10.1080/08927014.2020.1826939openalex-snapshot

Molecules involved in motility regulation inEscherichia colicells: a review

inferred← citeshttps://doi.org/10.1080/1040841x.2019.1700209openalex-snapshot

Pseudomonas aeruginosa and Staphylococcus aureus communication in biofilm infections: insights through network and database construction

inferred← citeshttps://doi.org/10.1080/1040841x.2020.1822278openalex-snapshot

Treatment strategies targeting persister cell formation in bacterial pathogens

inferred← citeshttps://doi.org/10.1080/1040841x.2023.2203766openalex-snapshot

Evolutionary principles for modifying pathogen virulence

inferred← citeshttps://doi.org/10.1080/1040841x.2024.2320823openalex-snapshot

Vibrio cholerae virulence and its suppression through the quorum-sensing system

inferred← citeshttps://doi.org/10.1080/13102818.2022.2106887openalex-snapshot

The concept for the antivirulence therapeutics approach as alternative to antibiotics: hope or still a fiction?

inferred← citeshttps://doi.org/10.1080/14728222.2026.2620600openalex-snapshot

Uncovering potential targets for MRSA infection treatment: a nanomedicine perspective

inferred← citeshttps://doi.org/10.1080/14787210.2021.1843427openalex-snapshot

Quorum sensing: a new prospect for the management of antimicrobial-resistant infectious diseases

inferred← citeshttps://doi.org/10.1080/20477724.2023.2285187openalex-snapshot

Staphylococcus aureus epidemiology, pathophysiology, clinical manifestations and application of nano-therapeutics as a promising approach to combat methicillin resistant Staphylococcus aureus

inferred← citeshttps://doi.org/10.1088/1748-605x/ac50f6openalex-snapshot

Bacterial biofilm infections, their resistance to antibiotics therapy and current treatment strategies

inferred← citeshttps://doi.org/10.1089/fpd.2024.0028openalex-snapshot

The ldh Gene Plays a Crucial Role in Mediating the Pathogen Control of Lactiplantibacillus plantarum AR113

inferred← citeshttps://doi.org/10.1093/femsle/fnab059openalex-snapshot

A ban on BAM: an update on inhibitors of the β-barrel assembly machinery

inferred← citeshttps://doi.org/10.1093/femsle/fnaf111openalex-snapshot

Human cell-derived extracellular vesicles exhibit anti-biofilm effects against Pseudomonas aeruginosa

inferred← citeshttps://doi.org/10.1093/femsre/fuaa041openalex-snapshot

Bacteriophages as drivers of bacterial virulence and their potential for biotechnological exploitation

inferred← citeshttps://doi.org/10.1093/femsre/fuac019openalex-snapshot

Evolution-proof inhibitors of public good cooperation: a screening strategy inspired by social evolution theory

inferred← citeshttps://doi.org/10.1093/femsre/fuad010openalex-snapshot

Bacterial virulence regulation through soluble peptidoglycan fragments sensing and response: knowledge gaps and therapeutic potential

inferred← citeshttps://doi.org/10.1093/jambio/lxad162openalex-snapshot

Natural cordiaquinones as strategies to inhibit the growth and biofilm formation of methicillin-sensitive and methicillin-resistantStaphylococcusspp

inferred← citeshttps://doi.org/10.1093/nar/gkab251openalex-snapshot

5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistantStaphylococcus aureusin mice

inferred← citeshttps://doi.org/10.1099/mic.0.001264openalex-snapshot

Unravelling microbial efflux through mathematical modelling

inferred← citeshttps://doi.org/10.1099/mic.0.001278openalex-snapshot

Adaptation of Pseudomonas aeruginosa biofilms to tobramycin and the quorum sensing inhibitor C-30 during experimental evolution requires multiple genotypic and phenotypic changes

inferred← citeshttps://doi.org/10.1101/2023.07.07.548074openalex-snapshot

Exploring alternative quorum sensing model structures and quorum quenching strategies

inferred← citeshttps://doi.org/10.1101/2025.11.13.688379openalex-snapshot

Emergence of Dual-Risk Klebsiella pneumoniae : Global Hotspots of Convergence Between Resistance and Hypervirulence

inferred← citeshttps://doi.org/10.1109/tmbmc.2025.3554671openalex-snapshot

Quorum Sensing Model Structures Inspire the Design of Quorum Quenching Strategies

inferred← citeshttps://doi.org/10.1111/apm.70041openalex-snapshot

Examining the Role of Virulence Proteins From Pathogenic Anaerobes in the Initiation of Colorectal Cancer

inferred← citeshttps://doi.org/10.1111/ele.13861openalex-snapshot

Would that it were so simple: Interactions between multiple traits undermine classical single‐trait‐based predictions of microbial community function and evolution

inferred← citeshttps://doi.org/10.1111/jam.15565openalex-snapshot

Perillaldehyde mitigates virulence factors and biofilm formation of Pseudomonas aeruginosa clinical isolates, by acting on the quorum sensing mechanism in vitro

inferred← citeshttps://doi.org/10.1111/jam.15601openalex-snapshot

Novel quinoline-based derivatives as the PqsR inhibitor against Pseudomonas aeruginosa PAO1

inferred← citeshttps://doi.org/10.1111/jvp.12962openalex-snapshot

Diagnostic clinical microbiology

inferred← citeshttps://doi.org/10.1111/php.13332openalex-snapshot

Effect of Sublethal Blue Light on Herbal Extract Activity Against Volatile Sulfide Compound Production by Fusobacterium nucleatum

inferred← citeshttps://doi.org/10.1128/aac.00565-24openalex-snapshot

A peptide targeting outer membrane protein A of Acinetobacter baumannii exhibits antibacterial activity by reducing bacterial pathogenicity

inferred← citeshttps://doi.org/10.1128/aem.00279-20openalex-snapshot

An α/β-Hydrolase Fold Subfamily Comprising Pseudomonas Quinolone Signal-Cleaving Dioxygenases

inferred← citeshttps://doi.org/10.1128/aem.01932-22openalex-snapshot

Disturbing the Spatial Organization of Biofilm Communities Affects Expression of agr -Regulated Virulence Factors in Staphylococcus aureus

inferred← citeshttps://doi.org/10.1128/jb.00034-23openalex-snapshot

The Arabinose 5-Phosphate Isomerase KdsD Is Required for Virulence in Burkholderia pseudomallei

inferred← citeshttps://doi.org/10.1128/jb.00156-20openalex-snapshot

Free Fatty Acids Interfere with the DNA Binding Activity of the Virulence Regulator PrfA of Listeria monocytogenes

inferred← citeshttps://doi.org/10.1128/mbio.00592-21openalex-snapshot

A Dual-Specificity Inhibitor Targets Polyphosphate Kinase 1 and 2 Enzymes To Attenuate Virulence of Pseudomonas aeruginosa

inferred← citeshttps://doi.org/10.1128/mbio.02376-23openalex-snapshot

The end of the reign of a “master regulator’’? A defect in function of the LasR quorum sensing regulator is a common feature of Pseudomonas aeruginosa isolates

inferred← citeshttps://doi.org/10.1128/mbio.03549-20openalex-snapshot

Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator

inferred← citeshttps://doi.org/10.1128/msphere.00151-26openalex-snapshot

Emerging pathogens in urinary tract infections: virulence and phenotypic characterization of Pseudomonas aeruginosa strains

inferred← citeshttps://doi.org/10.1128/spectrum.02327-25openalex-snapshot

Targeted sortase A inhibition by novel peptidomimetic antivirulents against staphylococcal infections

inferred← citeshttps://doi.org/10.1134/s1068162023010284openalex-snapshot

Chemical Compositions of Houttuynia cordata Thunb. Volatile Oil and Its Analogues Attenuate Staphylococcus aureus Virulence by Targeting α-Hemolysin

inferred← citeshttps://doi.org/10.1139/cjm-2020-0601openalex-snapshot

Old problems and new solutions: antibiotic alternatives in food animal production

inferred← citeshttps://doi.org/10.11606/t.42.2023.tde-15092023-110730openalex-snapshot

Atividade antifúngica de derivados 2-ariloxazolinas e miltefosina sobre >i /i i /i<

inferred← citeshttps://doi.org/10.1177/11779322221136002openalex-snapshot

Functional Analysis of Hypothetical Proteins of Vibrio parahaemolyticus Reveals the Presence of Virulence Factors and Growth-Related Enzymes With Therapeutic Potential

inferred← citeshttps://doi.org/10.1177/11779322241280580openalex-snapshot

Identification and Functional Annotation of Hypothetical Proteins of Pan-Drug-Resistant Providencia rettgeri Strain MRSN845308 Toward Designing Antimicrobial Drug Targets

inferred← citeshttps://doi.org/10.1186/s12866-023-03142-yopenalex-snapshot

Proportion of toxin and non-toxin virulence factors of Staphylococcus aureus isolates from diabetic foot infection: a systematic review and meta-analysis

inferred← citeshttps://doi.org/10.1186/s12903-022-02530-6openalex-snapshot

Advances in novel therapeutic approaches for periodontal diseases

inferred← citeshttps://doi.org/10.1186/s12906-024-04460-yopenalex-snapshot

Evidence on the inhibitory effect of Brassica plants against Acinetobacter baumannii lipases: phytochemical analysis, in vitro, and molecular docking studies

inferred← citeshttps://doi.org/10.1186/s12941-021-00485-0openalex-snapshot

Antibiotic resistance modifying ability of phytoextracts in anthrax biological agent Bacillus anthracis and emerging superbugs: a review of synergistic mechanisms

inferred← citeshttps://doi.org/10.1186/s12964-026-02674-wopenalex-snapshot

Hijacking the signal: a critical evaluation of quorum sensing inhibitors as a next-generation approach against Staphylococcus aureus

inferred← citeshttps://doi.org/10.1186/s13567-021-01015-8openalex-snapshot

Delivering the pain: an overview of the type III secretion system with special consideration for aquatic pathogens

inferred← citeshttps://doi.org/10.18502/ijm.v13i1.5491openalex-snapshot

Effect of azithromycin and phenylalanine-arginine beta-naphthylamide on quorum sensing and virulence factors in clinical isolates of Pseudomonas aeruginosa

inferred← citeshttps://doi.org/10.18502/ijm.v13i3.6399openalex-snapshot

Therapeutic effects, immunogenicity and cytotoxicity of a cell penetrating peptide-peptide nucleic acid conjugate against cagA of Helicobacter pylori in cell culture and animal model

inferred← citeshttps://doi.org/10.21070/acopen.10.2025.10792openalex-snapshot

Biofilm Formation and Antibiotic Resistance of Staphylococcus aureus Isolates

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2305070/v1openalex-snapshot

Unravelling the mechanism of autoinhibition by Pseudomonas aeruginosa aminopeptidase enables the development of a potent antibiofilm cyclic peptide

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2305070/v2openalex-snapshot

Unravelling the mechanism of autoinhibition by Pseudomonas aeruginosa aminopeptidase enables the development of a potent antibiofilm cyclic peptide

inferred← citeshttps://doi.org/10.21203/rs.3.rs-2679079/v1openalex-snapshot

In silico Identification of Novel Therapeutic Targets and Epitopes among the Essential Hypothetical Protein of Pseudomonas aeruginosa: A Novel Approach for Antivirulence Therapy

inferred← citeshttps://doi.org/10.21203/rs.3.rs-3297912/v1openalex-snapshot

Antibiotic susceptibility is associated with some of the virulence associated genes in Proteus isolates

inferred← citeshttps://doi.org/10.21203/rs.3.rs-8850063/v1openalex-snapshot

Genomic Plasticity and Antimicrobial Resistance Landscape of Egyptian Pseudomonas aeruginosa Clinical Strains

inferred← citeshttps://doi.org/10.2139/ssrn.4933938openalex-snapshot

Comprehensive Analysis of Antimicrobial Resistance, Biofilm Formation and Virulence Factors of Staphylococci Isolated from Bovine Mastitis

inferred← citeshttps://doi.org/10.2147/idr.s380883openalex-snapshot

An Explorative Review on Advanced Approaches to Overcome Bacterial Resistance by Curbing Bacterial Biofilm Formation

inferred← citeshttps://doi.org/10.2174/0115680266266646231023091215openalex-snapshot

Protein Dynamics Mediated by Cardiolipin in Bacteria

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