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Evolution of Innate Immunity: Clues from Invertebrates via Fish to Mammals

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bies.201300145openalex-snapshot
Evolution of adaptive immunity: Implications of a third lymphocyte lineage in lampreys
inferredcites →https://doi.org/10.1002/jez.b.22559openalex-snapshot
A tetrapod‐like repertoire of innate immune receptors and effectors for coelacanths
inferredcites →https://doi.org/10.1007/bf02817549openalex-snapshot
Antimicrobial defense of the earthworm
inferredcites →https://doi.org/10.1007/s00018-010-0458-8openalex-snapshot
An ancient cytokine, astakine, mediates circadian regulation of invertebrate hematopoiesis
inferredcites →https://doi.org/10.1007/s00239-011-9450-7openalex-snapshot
Evolution of Vertebrate Immunity: Sequence and Functional Analysis of the SEFIR Domain Family Member Act1
inferredcites →https://doi.org/10.1007/s00436-009-1661-0openalex-snapshot
Expression of immune-regulatory genes, arginase-2 and inducible nitric oxide synthase (iNOS), in two rainbow trout (Oncorhynchus mykiss) strains following exposure to Myxobolus cerebralis
inferredcites →https://doi.org/10.1016/j.bbrc.2009.11.018openalex-snapshot
Does fish represent an intermediate stage in the evolution of ureotelic cytosolic arginase I?
inferredcites →https://doi.org/10.1016/j.biochi.2008.08.002openalex-snapshot
Novel translationally controlled tumor protein homologue in the buccal gland secretion of Lampetra japonica
inferredcites →https://doi.org/10.1016/j.cub.2009.02.035openalex-snapshot
Invertebrate Allorecognition: The Origins of Histocompatibility
inferredcites →https://doi.org/10.1016/j.cyto.2008.08.011openalex-snapshot
unpaired (upd)-3 expression and other immune-related functions are stimulated by interleukin-8 in Drosophila melanogaster SL2 cell line
inferredcites →https://doi.org/10.1016/j.dci.2008.02.006openalex-snapshot
Rapid accumulation of an interleukin 17 homolog transcript in Crassostrea gigas hemocytes following bacterial exposure
inferredcites →https://doi.org/10.1016/j.dci.2009.08.001openalex-snapshot
The involvement of suppressors of cytokine signaling 2 (SOCS2) in immune defense responses of Chinese mitten crab Eriocheir sinensis
inferredcites →https://doi.org/10.1016/j.dci.2010.02.011openalex-snapshot
Evolution of thioester-containing proteins revealed by cloning and characterization of their genes from a cnidarian sea anemone, Haliplanella lineate
inferredcites →https://doi.org/10.1016/j.dci.2010.12.001openalex-snapshot
PAMP induced expression of immune relevant genes in head kidney leukocytes of rainbow trout (Oncorhynchus mykiss)
inferredcites →https://doi.org/10.1016/j.dci.2010.12.009openalex-snapshot
Invertebrate immune diversity
inferredcites →https://doi.org/10.1016/j.dci.2012.08.008openalex-snapshot
Regulation of cnidarian–dinoflagellate mutualisms: Evidence that activation of a host TGFβ innate immune pathway promotes tolerance of the symbiont
inferredcites →https://doi.org/10.1016/j.dci.2013.03.004openalex-snapshot
Molecular evolution of a polymorphic HSP40-like protein encoded in the histocompatibility locus of an invertebrate chordate
inferredcites →https://doi.org/10.1016/j.dci.2013.08.009openalex-snapshot
Molecular cloning and expression of TLR in the Eisenia andrei earthworm
inferredcites →https://doi.org/10.1016/j.fsi.2005.01.012openalex-snapshot
Inflammatory cells of teleostean fish: A review focusing on mast cells/eosinophilic granule cells and rodlet cells
inferredcites →https://doi.org/10.1016/j.fsi.2012.03.030openalex-snapshot
Identification and characterization of a putative lipopolysaccharide-induced TNF-α factor (LITAF) gene from Amphioxus (Branchiostoma belcheri): An insight into the innate immunity of Amphioxus and the evolution of LITAF
inferredcites →https://doi.org/10.1016/j.fsi.2013.01.014openalex-snapshot
Allograft inflammatory factor-1 stimulates hemocyte immune activation by enhancing phagocytosis and expression of inflammatory cytokines in Crassostrea gigas
inferredcites →https://doi.org/10.1016/j.fsi.2013.04.031openalex-snapshot
Molecular insights of the first gastropod TLR counterpart from disk abalone (Haliotis discus discus), revealing its transcriptional modulation under pathogenic stress
inferredcites →https://doi.org/10.1016/j.fsi.2013.08.030openalex-snapshot
The cytokine networks of adaptive immunity in fish
inferredcites →https://doi.org/10.1016/j.fsi.2014.02.010openalex-snapshot
Adaptive and innate immune molecules in developing rainbow trout, Oncorhynchus mykiss eggs and larvae: Expression of genes and occurrence of effector molecules
inferredcites →https://doi.org/10.1016/j.it.2003.11.005openalex-snapshot
On the origins of the adaptive immune system: novel insights from invertebrates and cold-blooded vertebrates
inferredcites →https://doi.org/10.1016/j.jip.2010.02.009openalex-snapshot
Vertebrate cytokines interleukin 12 and gamma interferon, but not interleukin 10, enhance phagocytosis in the annelid Eisenia hortensis
inferredcites →https://doi.org/10.1016/j.jip.2012.03.005openalex-snapshot
The scope of the crustacean immune system for disease control
inferredcites →https://doi.org/10.1016/j.jmb.2013.11.030openalex-snapshot
Prokaryotic Ancestry of Eukaryotic Protein Networks Mediating Innate Immunity and Apoptosis
inferredcites →https://doi.org/10.1016/j.plrev.2009.12.001openalex-snapshot
Evolution of immune systems from self/not self to danger to artificial immune systems (AIS)
inferredcites →https://doi.org/10.1016/j.tim.2013.04.005openalex-snapshot
Lose the battle to win the war: bacterial strategies for evading host inflammasome activation
inferredcites →https://doi.org/10.1016/j.vetpar.2012.12.032openalex-snapshot
Toxocara canis: Molecular basis of immune recognition and evasion
inferredcites →https://doi.org/10.1016/j.ygeno.2013.04.019openalex-snapshot
Identification and evolution of an NFAT gene involving Branchiostoma belcheri innate immunity
inferredcites →https://doi.org/10.1016/s0020-7519(01)00332-0openalex-snapshot
Interactions between monogenean parasites and their fish hosts
inferredcites →https://doi.org/10.1016/s0145-305x(00)00017-3openalex-snapshot
Production of reactive oxygen species by hemocytes of Biomphalaria glabrata: carbohydrate-specific stimulation
inferredcites →https://doi.org/10.1016/s0952-7915(01)00307-7openalex-snapshot
Scavenger receptors in innate immunity
inferredcites →https://doi.org/10.1016/s1050-4648(02)00156-0openalex-snapshot
Identification of a scavenger receptor homologue on nonspecific cytotoxic cells and evidence for binding to oligodeoxyguanosine
inferredcites →https://doi.org/10.1038/nature12826openalex-snapshot
Elephant shark genome provides unique insights into gnathostome evolution
inferredcites →https://doi.org/10.1038/ni.1913openalex-snapshot
IgT, a primitive immunoglobulin class specialized in mucosal immunity
inferredcites →https://doi.org/10.1038/nri2807openalex-snapshot
The origins of vertebrate adaptive immunity
inferredcites →https://doi.org/10.1042/bc20050049openalex-snapshot
Effects of tumour necrosis factor α (TNFα) on Mytilus haemocytes: role of stress‐activated mitogen‐activated protein kinases (MAPKs)
inferredcites →https://doi.org/10.1073/pnas.1213110109openalex-snapshot
MyD88-deficient Hydra reveal an ancient function of TLR signaling in sensing bacterial colonizers
inferredcites →https://doi.org/10.1073/pnas.1318843111openalex-snapshot
An amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1
inferredcites →https://doi.org/10.1074/jbc.m110.138560openalex-snapshot
Ancient Cytokines, the Role of Astakines as Hematopoietic Growth Factors
inferredcites →https://doi.org/10.1080/03079457.2010.508777openalex-snapshot
Advances in avian immunology—prospects for disease control: a review
inferredcites →https://doi.org/10.1093/gbe/evu012openalex-snapshot
Evolution of a Cellular Immune Response in Drosophila: A Phenotypic and Genomic Comparative Analysis
inferredcites →https://doi.org/10.1093/molbev/mst174openalex-snapshot
The Characterization of Sponge NLRs Provides Insight into the Origin and Evolution of This Innate Immune Gene Family in Animals
inferredcites →https://doi.org/10.1093/molbev/mst184openalex-snapshot
Ancient Origins of Vertebrate-Specific Innate Antiviral Immunity
inferredcites →https://doi.org/10.1098/rstb.2008.0157openalex-snapshot
Immune defence, parasite evasion strategies and their relevance for ‘macroscopic phenomena’ such as virulence
inferredcites →https://doi.org/10.1111/j.0105-2896.2004.00118.xopenalex-snapshot
Primitive complement system of invertebrates
inferredcites →https://doi.org/10.1111/j.0105-2896.2005.00319.xopenalex-snapshot
Phagocytosis: the convoluted way from nutrition to adaptive immunity
inferredcites →https://doi.org/10.1111/j.1365-2761.2004.00558.xopenalex-snapshot
The parasitic ciliate Ichthyophthirius multifiliis induces expression of immune relevant genes in rainbow trout, Oncorhynchus mykiss (Walbaum)
inferredcites →https://doi.org/10.1111/j.1365-2761.2012.01385.xopenalex-snapshot
Fish immune responses against endoparasitic nematodes – experimental models
inferredcites →https://doi.org/10.1111/j.1432-1033.2004.04102.xopenalex-snapshot
A (1→3)‐β‐ d ‐glucan recognition protein from the sponge Suberites domuncula
inferredcites →https://doi.org/10.1111/j.1469-185x.2009.00105.xopenalex-snapshot
The mast cell: an evolutionary perspective
inferredcites →https://doi.org/10.1111/jfd.12169openalex-snapshot
Epidermal response of rainbow trout to I chthyobodo necator: immunohistochemical and gene expression studies indicate a T h1‐/ T h2‐like switch
inferredcites →https://doi.org/10.1111/mmi.12214openalex-snapshot
Evasion of killing by human antibody and complement through multiple variations in the surface oligosaccharide of H aemophilus influenzae
inferredcites →https://doi.org/10.1126/science.7089565openalex-snapshot
Presence of Coelomocytes in the Primitive Chordate Amphioxus ( Branchiostoma lanceolatum )
inferredcites →https://doi.org/10.1182/blood-2010-11-320614openalex-snapshot
Crustacean hematopoiesis and the astakine cytokines
inferredcites →https://doi.org/10.1182/blood-2010-11-321448openalex-snapshot
Characterization of the mononuclear phagocyte system in zebrafish
inferredcites →https://doi.org/10.1186/1471-2164-9-498openalex-snapshot
Local and systemic gene expression responses of Atlantic salmon (Salmo salar L.) to infection with the salmon louse (Lepeophtheirus salmonis)
inferredcites →https://doi.org/10.1242/jeb.038315openalex-snapshot
Understanding the vertebrate immune system: insights from the reptilian perspective
inferredcites →https://doi.org/10.1371/journal.ppat.1001115openalex-snapshot
Involvement of the Cytokine MIF in the Snail Host Immune Response to the Parasite Schistosoma mansoni
inferredcites →https://doi.org/10.1615/critrevimmunol.v32.i6.10openalex-snapshot
M1 and M2 Macrophages: Oracles of Health and Disease
inferredcites →https://doi.org/10.1645/0022-3395(2001)087[0778:ionoik]2.0.co;2openalex-snapshot
Involvement of Nitric Oxide in Killing ofSchistosoma MansoniSporocysts by Hemocytes From ResistantBiomphalaria Glabrata
inferredcites →https://doi.org/10.18388/abp.2010_2431openalex-snapshot
The ancestry and cumulative evolution of immune reactions.
inferredcites →https://doi.org/10.4049/jimmunol.171.11.6006openalex-snapshot
Ikaros Family Members from the Agnathan Myxine glutinosa and the Urochordate Oikopleura dioica: Emergence of an Essential Transcription Factor for Adaptive Immunity
inferredcites →https://doi.org/10.4238/2013.november.22.15openalex-snapshot
Cloning, characterization, and expression of the macrophage migration inhibitory factor gene from the Pacific white shrimp Litopenaeus vannamei (Penaeidae)

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Transcriptome Sequencing of the Spleen of the Spotted Sea Bass (Lateolabrax Maculatus) after Nocardia Seriolae Infection
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Marine Fish Parasites: A Bibliometric Review
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Wound healing across the animal kingdom: Crosstalk between the immune system and the extracellular matrix
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Circadian rhythms mediate infection risk inDaphnia dentifera
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Immune and stress physiology of two captively‐housed tortoise species
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CD200R1L is a functional evolutionary conserved activating receptor in human neutrophils
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The hierarchical basis of serial homology and evolutionary novelty
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Identification and Characterization of a Novel GAPDH‐Derived Antimicrobial Peptide From Jellyfish
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The knowns and unknowns of cardiac autoimmunity in viral myocarditis
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From infection to repair: Understanding the workings of our innate immune cells
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Photorhabdus asymbiotica as an Insect and Human Pathogen
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Teleost Fish as an Experimental Model for Vaccine Development
inferred← citeshttps://doi.org/10.1007/978-1-4939-3566-6_1openalex-snapshot
Innate Immune Receptors
inferred← citeshttps://doi.org/10.1007/978-1-4939-8549-4_12openalex-snapshot
Flow Cytometry for the Immunotoxicologist
inferred← citeshttps://doi.org/10.1007/978-3-030-41769-7_4openalex-snapshot
Insect Defense Proteins and Peptides
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Immune Response in Mammals and Chickens
inferred← citeshttps://doi.org/10.1007/978-3-030-82315-3_11openalex-snapshot
Preliminary Characterization of Hemocyte and Immunity of Asian Horseshoe Crabs, Tachypleus tridentatus, and Carcinoscorpius rotundicauda in Captivity
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Immune Response to Microsporidia
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The Potential Use of Functional Ingredients with Probiotics as Immunostimulants
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When Plants and Animals First Met Fungi: Insights from the Evolution of Host Immune Systems
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Disease Ecology in Terrestrial Reptiles from Latin America: A Call for Research
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Bi-directional Transcription, Double-Stranded RNA and the Implications on Genome Evolution
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Exploring the Innate Immunity in Invertebrates
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Interactions Between Parasitic Ciliates and Their Hosts: Ichthyophthirius multifiliis and Cryptocaryon irritans as Examples
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The Immune System in Evolution
inferred← citeshttps://doi.org/10.1007/978-3-319-47377-2_1openalex-snapshot
Basic Immunobiology
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Macrophages in Invertebrates: From Insects and Crustaceans to Marine Bivalves
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Chronic Suppurative Otitis Media (CSOM): A Middle Ear Mucosal Disease
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Evolution of Immunity
inferred← citeshttps://doi.org/10.1007/978-3-319-76768-0_15openalex-snapshot
The Inflammatory Response of Urochordata: The Basic Process of the Ascidians’ Innate Immunity
inferred← citeshttps://doi.org/10.1007/978-3-319-76768-0_4openalex-snapshot
Platyhelminthes: Molecular Dissection of the Planarian Innate Immune System
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inferred← citeshttps://doi.org/10.1007/978-981-19-8520-1_2openalex-snapshot
Nucleic Acid-Mediated Inflammatory Diseases
inferred← citeshttps://doi.org/10.1007/978-981-95-1549-3_1openalex-snapshot
Advancements in Invertebrate Immunity
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Structural Elucidation of Immune Proteins in Invertebrates Using the Protein Data Bank
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Functional Genomics in Fish Immunology
inferred← citeshttps://doi.org/10.1007/978-981-97-8549-0_14openalex-snapshot
Immunity and Immunity Orchestration in Shrimp
inferred← citeshttps://doi.org/10.1007/s00018-019-03319-7openalex-snapshot
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A survey of TIR domain sequence and structure divergence
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Immunoglobulin-like receptors and the generation of innate immune memory
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Ancient fish lineages illuminate toll-like receptor diversification in early vertebrate evolution
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Temperature increases, hypoxia, and changes in food availability affect immunological biomarkers in the marine mussel Mytilus galloprovincialis
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A proteomics evaluation of the primary and secondary immune response of Biomphalaria straminea challenged by Schistosoma mansoni
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Protective Responses in Invertebrates
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Fungal, Viral, Multicelled Parasitic, and Protozoan Infections
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Interactions between the epithelial barrier and the microbiota in the reproductive tract
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Novel Immunomodulatory Therapies for Respiratory Pathologies
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Cellular Indoctrination: How the Tumor Microenvironment Reeducates Macrophages Towards Nefarious Ends
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Caspase-Regulated Mechanisms of Cell Death
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The Immune System of Bony Fish
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Host Defense Mechanisms Against Bacteria
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Immunopathology
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Antiretroviral therapy and its cerebral vascular toxicity
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The Human Immune Response
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The Human Immune Response
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The Impact of Parasites on Host Insect Epigenetics
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Survival of metazoan parasites in fish: Putting into context the protective immune responses of teleost fish
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Towards a structural and functional analysis of the immunoglobulin-fold proteome
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Function and regulation of thermosensitive ion channel TRPV4 in the immune system
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Modulation of fish immune function through behavioural fever
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Assessment of inflammasome and type I IFN responses to DNA viruses and DNA PAMPS
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Erythropoietin-Mediated Neuroprotection in Insects Suggests a Prevertebrate Evolution of Erythropoietin-Like Signaling
inferred← citeshttps://doi.org/10.1016/j.aaf.2018.07.006openalex-snapshot
Hemocytes transcriptome profile of the Chinese mitten crab (Eriocheir sinensis)
inferred← citeshttps://doi.org/10.1016/j.aanat.2021.151809openalex-snapshot
Evolution and medicine — The central role of anatomy
inferred← citeshttps://doi.org/10.1016/j.acvd.2017.06.001openalex-snapshot
Hypoxia and heart regeneration: A new paradoxical approach for cardioprotection
inferred← citeshttps://doi.org/10.1016/j.aqrep.2020.100327openalex-snapshot
Dietary replacement of fish meal with peanut meal in juvenile hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂): Growth performance, immune response and intestinal microbiota
inferred← citeshttps://doi.org/10.1016/j.aqrep.2020.100571openalex-snapshot
Immune related gene expression analysis of Macrobrachium nipponense in different hours post-infection by non-O1 Vibrio cholerae
inferred← citeshttps://doi.org/10.1016/j.aqrep.2023.101771openalex-snapshot
Dietary postbiotics supplementation improves growth, survival rate, antioxidant capacity, non-specific immunity and gut health of juvenile oriental river prawn (Macrobrachium nipponense)
inferred← citeshttps://doi.org/10.1016/j.aqrep.2024.102181openalex-snapshot
Potential effects of Sargassum kjellmanianum as a dietary supplement on the growth performance, immunity response, antioxidant status, and ammonia resistance of yellow catfish (Pelteobagrus fulvidraco)
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2019.734299openalex-snapshot
Production and application of monoclonal antibodies against C-type lectins in scallop Chlamys farreri
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2020.735230openalex-snapshot
A formulated diet improved digestive capacity, immune function and intestinal microbiota structure of juvenile hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂) when compared with chilled trash fish
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2020.735309openalex-snapshot
Low-gossypol cottonseed protein concentrate used as a replacement of fish meal for juvenile hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂): Effects on growth performance, immune responses and intestinal microbiota
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2020.735671openalex-snapshot
Enhanced immune responses and protection against the secondary infection in mud crab (Scylla paramamosain) primed with formalin-killed Vibrio parahemolyticus
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2020.735831openalex-snapshot
Immune priming in shellfish: A review and an updating mechanistic insight focused on cellular and humoral responses
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2020.736309openalex-snapshot
Genome-wide analysis of TRAF gene family and its response to bacterial infection in noble scallop Chlamys nobilis with different carotenoids content
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2021.737038openalex-snapshot
Effects of dietary Lactobacillus helveticus on the growth rate, disease resistance and intestinal health of pond loach (Misgurnus anguillicaudatus)
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2021.737191openalex-snapshot
A novel screening method for the detection of Pseudoalteromonas shioyasakiensis, an emerging opportunistic pathogen that caused the mass mortality of juvenile Pacific abalone (Haliotis discus hannai) during a record-breaking heat wave
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2021.737383openalex-snapshot
Three naturally occurring host defense peptides protect largemouth bass (Micropterus salmoides) against bacterial infections
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2024.741178openalex-snapshot
Unveiling the molecular regulatory mechanisms of immune responses in the spleen of spotted sea bass (Lateolabrax maculatus) against Nocardia seriolae infection
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2025.742670openalex-snapshot
Cross-species single-cell atlas of hemocyte conservation and diversification in crustaceans
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2026.744426openalex-snapshot
Mapping the dynamics of teleost mucin biosynthesis in mucous cells under physiological and immersion vaccination conditions in flounder (Paralichthys olivaceus)
inferred← citeshttps://doi.org/10.1016/j.aquaculture.2026.744474openalex-snapshot
Identification of m6A regulators and MeRIP-Seq reveal positive m6A methylation associated with antiviral responses in head kidney lymphocytes of Nile tilapia
inferred← citeshttps://doi.org/10.1016/j.aquatox.2025.107308openalex-snapshot
Immune response to polystyrene microplastics: Regulation of inflammatory response via the ROS-driven NF-κB pathway in zebrafish (Danio rerio)
inferred← citeshttps://doi.org/10.1016/j.aquatox.2025.107501openalex-snapshot
Microplastic toxicity in aquatic organisms across phylogeny
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2018.11.015openalex-snapshot
Biased perspectives on formyl peptide receptors
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.121205openalex-snapshot
Healing through the lens of immunothrombosis: Biology-inspired, evolution-tailored, and human-engineered biomimetic therapies
inferred← citeshttps://doi.org/10.1016/j.cbd.2019.100597openalex-snapshot
Whole transcriptome analysis of the Atlantic cod vaccine response reveals subtle changes in adaptive immunity
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111506openalex-snapshot
An anti-inflammatory transcriptional cascade conserved from flies to humans
inferred← citeshttps://doi.org/10.1016/j.cirep.2024.200194openalex-snapshot
Current understanding of immune-like responses in worms
inferred← citeshttps://doi.org/10.1016/j.coisb.2017.04.003openalex-snapshot
Treatable traits and therapeutic targets: Goals for systems biology in infectious disease
inferred← citeshttps://doi.org/10.1016/j.cris.2024.100105openalex-snapshot
Experimental adaptation to singular pathogen challenge reduces susceptibility to novel pathogens in Drosophila melanogaster
inferred← citeshttps://doi.org/10.1016/j.cvfa.2021.06.007openalex-snapshot
Honey Bee (Apis mellifera) Immunity
inferred← citeshttps://doi.org/10.1016/j.dci.2015.05.001openalex-snapshot
IL-17 signaling components in bivalves: Comparative sequence analysis and involvement in the immune responses
inferred← citeshttps://doi.org/10.1016/j.dci.2015.08.001openalex-snapshot
Ixodes ricinus defensins attack distantly-related pathogens
inferred← citeshttps://doi.org/10.1016/j.dci.2015.08.002openalex-snapshot
CgIL17-5, an ancient inflammatory cytokine in Crassostrea gigas exhibiting the heterogeneity functions compared with vertebrate interleukin17 molecules
inferred← citeshttps://doi.org/10.1016/j.dci.2015.09.006openalex-snapshot
An LRR-only protein representing a new type of pattern recognition receptor in Chlamys farreri
inferred← citeshttps://doi.org/10.1016/j.dci.2016.01.014openalex-snapshot
Immunity to gastrointestinal microparasites of fish
inferred← citeshttps://doi.org/10.1016/j.dci.2016.01.019openalex-snapshot
Serum amyloid A in marine bivalves: An acute phase and innate immunity protein
inferred← citeshttps://doi.org/10.1016/j.dci.2016.02.001openalex-snapshot
A new subfamily of penaeidin with an additional serine-rich region from kuruma shrimp (Marsupenaeus japonicus) contributes to antimicrobial and phagocytic activities
inferred← citeshttps://doi.org/10.1016/j.dci.2017.09.007openalex-snapshot
Comparison of phagocytosis in three Caribbean Sea urchins
inferred← citeshttps://doi.org/10.1016/j.dci.2018.01.005openalex-snapshot
Canine macrophages can like human macrophages be in vitro activated toward the M2a subtype relevant in allergy
inferred← citeshttps://doi.org/10.1016/j.dci.2018.06.008openalex-snapshot
SpToll1 and SpToll2 modulate the expression of antimicrobial peptides in Scylla paramamosain
inferred← citeshttps://doi.org/10.1016/j.dci.2018.11.018openalex-snapshot
Imaging flow cytometry and confocal microscopy-based examination of F-actin and phosphoinositide dynamics during leukocyte immune-type receptor-mediated phagocytic events
inferred← citeshttps://doi.org/10.1016/j.dci.2019.01.010openalex-snapshot
Derivatives of the lectin complement pathway in Lophotrochozoa
inferred← citeshttps://doi.org/10.1016/j.dci.2019.04.004openalex-snapshot
Hemolymph C1qDC promotes the phagocytosis of oyster Crassostrea gigas hemocytes by interacting with the membrane receptor β-integrin
inferred← citeshttps://doi.org/10.1016/j.dci.2019.103485openalex-snapshot
The immunobiological interplay between Pseudosuccinea columella resistant/susceptible snails with Fasciola hepatica: Hemocytes in the spotlight
inferred← citeshttps://doi.org/10.1016/j.dci.2019.103498openalex-snapshot
The involvement of TLR signaling and anti-bacterial effectors in enhanced immune protection of oysters after Vibrio splendidus pre-exposure
inferred← citeshttps://doi.org/10.1016/j.dci.2019.103532openalex-snapshot
Complement C1q subunit molecules from Xenopus laevis possess conserved function in C1q-immunoglobulin interaction
inferred← citeshttps://doi.org/10.1016/j.dci.2021.104131openalex-snapshot
Progresses on three pattern recognition receptor families (TLRs, RLRs and NLRs) in teleost
inferred← citeshttps://doi.org/10.1016/j.dci.2021.104245openalex-snapshot
Why and how do protective symbionts impact immune priming with pathogens in invertebrates?
inferred← citeshttps://doi.org/10.1016/j.dci.2024.105147openalex-snapshot
Natural selection directing molecular evolution in vertebrate viral sensors
inferred← citeshttps://doi.org/10.1016/j.dci.2024.105253openalex-snapshot
Molecular characterization and gene expression of pattern recognition receptors in brown-marbled grouper (Epinephelus fuscoguttatus) fingerlings responding to vibriosis infection
inferred← citeshttps://doi.org/10.1016/j.dci.2025.105477openalex-snapshot
Ring Finger protein 34 negatively regulates MyD88-mediated NF-κB signaling via the ubiquitin-proteasome pathway in miiuy croaker (Miichthys miiuy)
inferred← citeshttps://doi.org/10.1016/j.dci.2025.105494openalex-snapshot
A chitin binding protein from the kuruma shrimp Marsupenaeus japonicus involved in WSSV infection
inferred← citeshttps://doi.org/10.1016/j.dci.2026.105607openalex-snapshot
Immune-relevant transcripts of the mollusc Succinea putris (Gastropoda, Pulmonata)
inferred← citeshttps://doi.org/10.1016/j.dci.2026.105695openalex-snapshot
Comparative anti-viral immune strategies in insects and vertebrates: Insights from Bombyx mori
inferred← citeshttps://doi.org/10.1016/j.devcel.2016.07.008openalex-snapshot
The Software and Hardware of Macrophages: A Diversity of Options
inferred← citeshttps://doi.org/10.1016/j.devcel.2022.05.009openalex-snapshot
Macrophages, masters of invasion
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2017.06.060openalex-snapshot
Probing safety of nanoparticles by outlining sea urchin sensing and signaling cascades
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2020.111109openalex-snapshot
Microplastic pollution as a grand challenge in marine research: A closer look at their adverse impacts on the immune and reproductive systems
inferred← citeshttps://doi.org/10.1016/j.envres.2023.116600openalex-snapshot
Review of cadmium toxicity effects on fish: Oxidative stress and immune responses
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2018.09.036openalex-snapshot
Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.01.038openalex-snapshot
Myeloperoxidase-deficient zebrafish show an augmented inflammatory response to challenge with Candida albicans
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.04.029openalex-snapshot
Identification and functional characterization of the CSF1R gene from grass carp Ctenopharyngodon idellus and its use as a marker of monocytes/macrophages
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.04.032openalex-snapshot
Immunolocalization of tumor necrosis factor alpha in turbot (Scophthalmus maximus, L.) tissues
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.09.043openalex-snapshot
Occurrence of immune cells in the intestinal wall of Squalius cephalus infected with Pomphorhynchus laevis
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.11.031openalex-snapshot
Microarray analysis of gene expression in olive flounder liver infected with viral haemorrhagic septicaemia virus (VHSV)
inferred← citeshttps://doi.org/10.1016/j.fsi.2015.12.006openalex-snapshot
Alterations of the immune transcriptome in resistant and susceptible hard clams (Mercenaria mercenaria) in response to Quahog Parasite Unknown (QPX) and temperature
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.02.002openalex-snapshot
Fish innate immunity against intestinal helminths
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.04.125openalex-snapshot
Toll-like receptors in maraena whitefish: Evolutionary relationship among salmonid fishes and patterns of response to Aeromonas salmonicida
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.06.051openalex-snapshot
De novo annotation of the immune-enriched transcriptome provides insights into immune system genes of Chinese sturgeon (Acipenser sinensis)
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.08.021openalex-snapshot
PcToll3 was involved in anti- Vibrio response by regulating the expression of antimicrobial peptides in red swamp crayfish, Procambarus clarkii
inferred← citeshttps://doi.org/10.1016/j.fsi.2016.10.045openalex-snapshot
Toxic effects in juvenile sea cucumber Apostichopus japonicas (Selenka) exposure to benzo[ a ]pyrene
inferred← citeshttps://doi.org/10.1016/j.fsi.2017.06.019openalex-snapshot
Immune response of olive flounder ( Paralichthys olivaceus ) infected with the myxosporean parasite Kudoa septempunctata
inferred← citeshttps://doi.org/10.1016/j.fsi.2017.08.011openalex-snapshot
Deep transcriptome profiling sheds light on key players in nucleus implantation induced immune response in the pearl oyster Pinctada martensii
inferred← citeshttps://doi.org/10.1016/j.fsi.2017.09.023openalex-snapshot
Two novel LRR and Ig domain-containing proteins from oyster Crassostrea gigas function as pattern recognition receptors and induce expression of cytokines
inferred← citeshttps://doi.org/10.1016/j.fsi.2017.10.015openalex-snapshot
As-CATH4 and 5, two vertebrate-derived natural host defense peptides, enhance the immuno-resistance efficiency against bacterial infections in Chinese mitten crab, Eriocheir sinensis
inferred← citeshttps://doi.org/10.1016/j.fsi.2017.10.058openalex-snapshot
Inducers of salmon innate immunity: An in vitro and in vivo approach
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.02.010openalex-snapshot
Antibacterial activity of hemocyanin from red swamp crayfish (Procambarus clarkii)
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.03.056openalex-snapshot
Identification of clam plasma proteins that bind its pathogen Quahog Parasite Unknown
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.04.026openalex-snapshot
Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.09.051openalex-snapshot
Comparative transcriptome analysis of red swamp crayfish (Procambarus clarkia) hepatopancreas in response to WSSV and Aeromonas hydrophila infection
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.09.067openalex-snapshot
Do the toll-like receptors and complement systems play equally important roles in freshwater adapted Dolly Varden char (Salvelinus malma)?
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.10.005openalex-snapshot
Identification of an anti-lipopolysaccharide factor AV-R isoform (LvALF AV-R) related to Vp_PirAB-like toxin resistance in Litopenaeus vannamei
inferred← citeshttps://doi.org/10.1016/j.fsi.2018.11.075openalex-snapshot
Transcriptomic analysis of immunity in rainbow trout (Oncorhynchus mykiss) gills infected by Ichthyophthirius multifiliis
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.01.050openalex-snapshot
The pathogenicity characterization of non-O1 Vibrio cholerae and its activation on immune system in freshwater shrimp Macrobrachium nipponense
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.03.032openalex-snapshot
Lipid droplets participate in modulating innate immune genes in Ctenopharyngodon idella kidney cells
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.03.059openalex-snapshot
A novel invertebrate toll-like receptor with broad recognition spectrum from thick shell mussel Mytilus coruscus
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.05.005openalex-snapshot
The immune function of prophenoloxidase from red swamp crayfish (Procambarus clarkii) in response to bacterial infection
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.07.019openalex-snapshot
Expansion and loss events characterized the occurrence of MIF-like genes in bivalves
inferred← citeshttps://doi.org/10.1016/j.fsi.2019.08.057openalex-snapshot
Dynamic immune and metabolism response of clam Meretrix petechialis to Vibrio challenge revealed by a time series of transcriptome analysis
inferred← citeshttps://doi.org/10.1016/j.fsi.2020.02.018openalex-snapshot
Evolutionary and functional analysis of MyD88 genes in pearl oyster Pinctada fucata martensii
inferred← citeshttps://doi.org/10.1016/j.fsi.2020.05.004openalex-snapshot
Haplosporidian host:parasite interactions
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.03.020openalex-snapshot
Microglia extracellular traps in Oreochromis niloticus infected with Weissella cibaria
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.04.022openalex-snapshot
A fibrinogen-related protein mediates the recognition of various bacteria and haemocyte phagocytosis in oyster Crassostrea gigas
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.05.020openalex-snapshot
Identification and characterization of a C-type lectin in turbot (Scophthalmus maximus) which functioning as a pattern recognition receptor that binds and agglutinates various bacteria
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.07.015openalex-snapshot
A proteomics investigation of ‘immune priming’ in Penaeus vannamei as shown by isobaric tags for relative and absolute quantification
inferred← citeshttps://doi.org/10.1016/j.fsi.2021.10.022openalex-snapshot
The conservation and diversity of ascidian cells and molecules involved in the inflammatory reaction: The Ciona robusta model
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.01.024openalex-snapshot
Extracellular traps involved in invertebrate immune mechanisms
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.04.010openalex-snapshot
Fish-specific Toll-like receptor 14 (TLR14) from Asian swamp eel (Monopterus albus) is involved in immune response to bacterial infection
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.06.048openalex-snapshot
Blunt snout bream (Megalobrama amblycephala) MaCSF-1 contributes to proliferation, phagocytosis and immunoregulation of macrophages via MaCSF-1R
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.06.061openalex-snapshot
Identification and functional analysis of Mannose receptor in Asian swamp eel (Monopterus albus) in response to bacterial infection
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.10.027openalex-snapshot
Identification and functional characterization of CL-11 in black rockfish (Sebastes schlegelii)
inferred← citeshttps://doi.org/10.1016/j.fsi.2022.108453openalex-snapshot
Phenotypic and functional characterization of two coelomocyte subsets in Apostichopus japonicus
inferred← citeshttps://doi.org/10.1016/j.fsi.2024.109371openalex-snapshot
The early ontogenetic development of immune cells and organs in teleosts
inferred← citeshttps://doi.org/10.1016/j.fsi.2024.109490openalex-snapshot
What can we learn about fish neutrophil and macrophage response to immune challenge from studies in zebrafish
inferred← citeshttps://doi.org/10.1016/j.fsi.2024.109571openalex-snapshot
Fish arginase constrains excessive production of nitric oxide and limits mitochondrial damage during Aeromonas hydrophila infection
inferred← citeshttps://doi.org/10.1016/j.fsi.2024.109946openalex-snapshot
The role of pattern recognition receptors in the innate immune system of Chinese mitten crab (Eriocheir sinensis)
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110187openalex-snapshot
Shark immune system: A review about their immunoglobulin repertoire
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110227openalex-snapshot
Eriocheir sinensis CD63 activate mitochondria-mediated apoptosis to resist Spiroplasma eriocheiris infection
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.110236openalex-snapshot
Histone lysine demethylase 5 regulates haemocyte proliferation during immune priming in the oyster Crassostrea gigas
inferred← citeshttps://doi.org/10.1016/j.fsi.2025.111055openalex-snapshot
Diazepam exerts immunosuppressive effects on macrophages isolated from the head kidney of catfish (Silurus asotus)
inferred← citeshttps://doi.org/10.1016/j.fsi.2026.111278openalex-snapshot
The ammonia transporter gene family and its immune regulatory role in the Pacific oyster (Crassostrea gigas)
inferred← citeshttps://doi.org/10.1016/j.fsi.2026.111587openalex-snapshot
Toll-like receptor 2 (TLR2) functions as a key regulator of inflammatory responses to Vibrio parahaemolyticus infection in the Manila clam (Ruditapes philippinarum)
inferred← citeshttps://doi.org/10.1016/j.gde.2019.07.011openalex-snapshot
Gene conversion generates evolutionary novelty that fuels genetic conflicts
inferred← citeshttps://doi.org/10.1016/j.genrep.2021.101190openalex-snapshot
Birth and death of CYLD paralogues in vertebrates
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2017.07.034openalex-snapshot
Immune response of anti-lectin Pjlec antibody in freshwater crab Paratelphusa jacquemontii
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2020.07.293openalex-snapshot
Structure of fish Toll-like receptors (TLR) and NOD-like receptors (NLR)
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2023.128729openalex-snapshot
UNC93B1 facilitates the localization and signaling of TLR5M in Epinephelus coioides
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