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Interleukin-6 Trans-Signaling Pathway Promotes Immunosuppressive Myeloid-Derived Suppressor Cells via Suppression of Suppressor of Cytokine Signaling 3 in Breast Cancer
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1 of the 64 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.1074/jbc.m113.525014 (notice 2021-04-29).
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ijc.27318openalex-snapshot
Role of SOCS1 in tumor progression and therapeutic application
inferredcites →https://doi.org/10.1007/s00109-012-0916-xopenalex-snapshot
Significance of IL-6 in the transition of hormone-resistant prostate cancer and the induction of myeloid-derived suppressor cells
inferredcites →https://doi.org/10.1007/s00262-011-1028-0openalex-snapshot
Elevated myeloid-derived suppressor cells in pancreatic, esophageal and gastric cancer are an independent prognostic factor and are associated with significant elevation of the Th2 cytokine interleukin-13
inferredcites →https://doi.org/10.1007/s00262-014-1591-2openalex-snapshot
Correlation between frequencies of blood monocytic myeloid-derived suppressor cells, regulatory T cells and negative prognostic markers in patients with castration-resistant metastatic prostate cancer
inferredcites →https://doi.org/10.1016/bs.acr.2015.04.002openalex-snapshot
Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1016/j.breast.2016.09.002openalex-snapshot
Tumor microenvironment-mediated chemoresistance in breast cancer
inferredcites →https://doi.org/10.1016/j.canlet.2011.04.024openalex-snapshot
Suppression of SOCS3 in macrophages prevents cancer metastasis by modifying macrophage phase and MCP2/CCL8 induction
inferredcites →https://doi.org/10.1016/j.canlet.2016.07.012openalex-snapshot
Interleukin-10 attenuates tumour growth by inhibiting interleukin-6/signal transducer and activator of transcription 3 signalling in myeloid-derived suppressor cells
inferredcites →https://doi.org/10.1016/j.ccr.2007.12.004openalex-snapshot
Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis
inferredcites →https://doi.org/10.1016/j.ccr.2009.01.001openalex-snapshot
IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
inferredcites →https://doi.org/10.1016/j.ccr.2011.03.009openalex-snapshot
Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
inferredcites →https://doi.org/10.1016/j.immuni.2011.12.015openalex-snapshot
Suppression of Cytokine Signaling by SOCS3: Characterization of the Mode of Inhibition and the Basis of Its Specificity
inferredcites →https://doi.org/10.1016/j.pharmthera.2013.09.004openalex-snapshot
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers
inferredcites →https://doi.org/10.1016/j.smim.2013.11.002openalex-snapshot
Interleukin-6: From basic biology to selective blockade of pro-inflammatory activities
inferredcites →https://doi.org/10.1016/j.smim.2013.12.004openalex-snapshot
Inhibition of IL-6 family cytokines by SOCS3
inferredcites →https://doi.org/10.1016/s0014-5793(00)02205-5openalex-snapshot
Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor
inferredcites →https://doi.org/10.1016/s0092-8674(00)80047-1openalex-snapshot
SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine
inferredcites →https://doi.org/10.1016/s0171-2985(00)80052-2openalex-snapshot
Multi-Color Analysis of Monocyte and Dendritic Cell Precursor Heterogeneity in Whole Blood
inferredcites →https://doi.org/10.1016/s1074-7613(00)00078-9openalex-snapshot
Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1
inferredcites →https://doi.org/10.1016/s1074-7613(00)80011-4openalex-snapshot
Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells
inferredcites →https://doi.org/10.1038/43206openalex-snapshot
A family of cytokine-inducible inhibitors of signalling
inferredcites →https://doi.org/10.1038/43219openalex-snapshot
Structure and function of a new STAT-induced STAT inhibitor
inferredcites →https://doi.org/10.1038/nbt1035openalex-snapshot
Silencing of SOCS1 enhances antigen presentation by dendritic cells and antigen-specific anti-tumor immunity
inferredcites →https://doi.org/10.1038/ncomms12150openalex-snapshot
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
inferredcites →https://doi.org/10.1038/ncponc0195openalex-snapshot
Mechanisms of Disease: insights into the emerging role of signal transducers and activators of transcription in cancer
inferredcites →https://doi.org/10.1038/ni.2526openalex-snapshot
Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer
inferredcites →https://doi.org/10.1038/ni931openalex-snapshot
SOCS3 negatively regulates IL-6 signaling in vivo
inferredcites →https://doi.org/10.1038/nrc2734openalex-snapshot
STATs in cancer inflammation and immunity: a leading role for STAT3
inferredcites →https://doi.org/10.1038/nri2506openalex-snapshot
Myeloid-derived suppressor cells as regulators of the immune system
inferredcites →https://doi.org/10.1038/nri3175openalex-snapshot
Coordinated regulation of myeloid cells by tumours
inferredcites →https://doi.org/10.1038/sj.onc.1208437openalex-snapshot
A SOCS-1 peptide mimetic inhibits both constitutive and IL-6 induced activation of STAT3 in prostate cancer cells
inferredcites →https://doi.org/10.1038/srep44053openalex-snapshot
Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling
inferredcites →https://doi.org/10.1042/bj20030407openalex-snapshot
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
inferredcites →https://doi.org/10.1053/j.gastro.2006.10.037openalex-snapshot
Sustained IL-6/STAT-3 Signaling in Cholangiocarcinoma Cells Due to SOCS-3 Epigenetic Silencing
inferredcites →https://doi.org/10.1073/pnas.1108121108openalex-snapshot
Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model
inferredcites →https://doi.org/10.1074/jbc.275.17.12848openalex-snapshot
SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130
inferredcites →https://doi.org/10.1074/jbc.m113.525014openalex-snapshot
Blockade of Fas Signaling in Breast Cancer Cells Suppresses Tumor Growth and Metastasis via Disruption of Fas Signaling-initiated Cancer-related Inflammation
inferredcites →https://doi.org/10.1074/jbc.m115.682138openalex-snapshot
Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex
inferredcites →https://doi.org/10.1074/jbc.m210584200openalex-snapshot
Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)
inferredcites →https://doi.org/10.1080/2162402x.2015.1004983openalex-snapshot
Phenotype, development, and biological function of myeloid-derived suppressor cells
inferredcites →https://doi.org/10.1080/2162402x.2015.1034918openalex-snapshot
Cancer associated fibroblasts have phenotypic and functional characteristics similar to the fibrocytes that represent a novel MDSC subset
inferredcites →https://doi.org/10.1155/2011/469135openalex-snapshot
Upregulated Expression of Indoleamine 2, 3-Dioxygenase in Primary Breast Cancer Correlates with Increase of Infiltrated Regulatory T CellsIn Situand Lymph Node Metastasis
inferredcites →https://doi.org/10.1158/0008-5472.can-07-2354openalex-snapshot
Reduced Inflammation in the Tumor Microenvironment Delays the Accumulation of Myeloid-Derived Suppressor Cells and Limits Tumor Progression
inferredcites →https://doi.org/10.1158/0008-5472.can-08-4709openalex-snapshot
The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies
inferredcites →https://doi.org/10.1158/0008-5472.can-12-4601openalex-snapshot
Pancreatic Cancer-Associated Stellate Cells Promote Differentiation of Myeloid-Derived Suppressor Cells in a STAT3-Dependent Manner
inferredcites →https://doi.org/10.1158/1078-0432.ccr-13-2508openalex-snapshot
Myeloid-Derived Suppressor Cells Predict Survival of Patients with Advanced Melanoma: Comparison with Regulatory T Cells and NY-ESO-1- or Melan-A–Specific T Cells
inferredcites →https://doi.org/10.1158/2326-6066.cir-15-0004openalex-snapshot
SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells
inferredcites →https://doi.org/10.1182/blood.v86.8.3097.3097openalex-snapshot
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87
inferredcites →https://doi.org/10.1186/bcr3473openalex-snapshot
A mutual activation loop between breast cancer cells and myeloid-derived suppressor cells facilitates spontaneous metastasis through IL-6 trans-signaling in a murine model
inferredcites →https://doi.org/10.1369/jhc.2010.956644openalex-snapshot
Enhanced Expression of CD13 in Vessels of Inflammatory and Neoplastic Tissues
inferredcites →https://doi.org/10.1371/journal.pgen.1003444openalex-snapshot
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases
inferredcites →https://doi.org/10.18632/oncotarget.11352openalex-snapshot
Suppressive role of myeloid-derived suppressor cells (MDSCs) in the microenvironment of breast cancer and targeted immunotherapies
inferredcites →https://doi.org/10.18632/oncotarget.2368openalex-snapshot
IL-6-stimulated CD11b+CD14+HLA-DR− myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus
inferredcites →https://doi.org/10.18632/oncotarget.6083openalex-snapshot
The bone marrow microenvironment enhances multiple myeloma progression by exosome-mediated activation of myeloid-derived suppressor cells
inferredcites →https://doi.org/10.3389/fimmu.2012.00020openalex-snapshot
SOCS, Inflammation, and Autoimmunity
inferredcites →https://doi.org/10.3389/fimmu.2017.00070openalex-snapshot
Dysregulation of SOCS-Mediated Negative Feedback of Cytokine Signaling in Carcinogenesis and Its Significance in Cancer Treatment
inferredcites →https://doi.org/10.3390/ijms18020405openalex-snapshot
Tumor Microenvironment, a Paradigm in Hepatocellular Carcinoma Progression and Therapy
inferredcites →https://doi.org/10.4049/jimmunol.1201449openalex-snapshot
Myeloid-Derived Suppressor Cells Suppress Antitumor Immune Responses through IDO Expression and Correlate with Lymph Node Metastasis in Patients with Breast Cancer
inferredcites →https://doi.org/10.4049/jimmunol.1400833openalex-snapshot
Noncanonical NF-κB Activation Mediates STAT3-Stimulated IDO Upregulation in Myeloid-Derived Suppressor Cells in Breast Cancer
inferredcites →https://doi.org/10.4049/jimmunol.168.7.3181openalex-snapshot
Suppressors of Cytokine Signaling Proteins Are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance
inferredcites →https://doi.org/10.4049/jimmunol.169.3.1219openalex-snapshot
Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction
inferredcites →https://doi.org/10.4049/jimmunol.172.4.2307openalex-snapshot
Dendritic Cell Maturation Requires STAT1 and Is under Feedback Regulation by Suppressors of Cytokine Signaling
inferredcites →https://doi.org/10.4049/jimmunol.179.2.977openalex-snapshot
Cross-Talk between Myeloid-Derived Suppressor Cells and Macrophages Subverts Tumor Immunity toward a Type 2 Response
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Disruption of CD47-SIRPα Signalling Restores Inflammatory Function in Tumour-Associated Myeloid Derived Suppressor Cells
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KAT6A Acetylation of SMAD3 Regulates Myeloid‐Derived Suppressor Cell Recruitment, Metastasis, and Immunotherapy in Triple‐Negative Breast Cancer
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Blueberry extract and its bioactive compounds mitigate oxidative stress and suppress human lung cancer cell (A549) growth by modulating the expression of p53/EGFR/STAT3/IL6‐mediated signaling molecules
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Delineation of monocytic and early‐stage myeloid‐derived suppressor cells in the peripheral blood of patients with hepatocarcinoma
inferred← citeshttps://doi.org/10.1002/jcp.26901openalex-snapshot
Analysis of pro‐ and anti‐inflammatory cytokine gene variants and serum cytokine levels as prognostic markers in breast cancer
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inferred← citeshttps://doi.org/10.1007/978-3-030-91311-3_7openalex-snapshot
The Role of Myeloid-Derived Suppressor Cells in Tumor Growth and Metastasis
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GITRL impairs the immunosuppressive function of MDSCs via PTEN-mediated signaling pathway in experimental Sjögren syndrome
inferred← citeshttps://doi.org/10.1007/s00262-020-02592-xopenalex-snapshot
Cysteine cathepsins L and X differentially modulate interactions between myeloid-derived suppressor cells and tumor cells
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Baseline IL-6 independently predicts severe immune-related toxicity and poor survival in advanced gastric cancer treated with immunotherapy
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Revolutionizing cancer treatment: an in-depth exploration of CAR-T cell therapies
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Dual roles of myeloid-derived suppressor cells in various diseases: a review
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MicroRNAs mediated interaction of tumor microenvironment cells with breast cancer cells during bone metastasis
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Components of cancer stem cells microenvironment: influence on the tumorigenic property and stemness in cancer stem cells
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inferred← citeshttps://doi.org/10.1016/j.ajt.2024.03.022openalex-snapshot
Myeloid-derived suppressor cells promote allograft survival by suppressing regulatory T cell dysfunction in high-risk corneal transplantation
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ADAM proteases in cytokine biology: Modulators of immune signaling, inflammation and cancer
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The RNA m6A writer METTL14 in cancers: Roles, structures, and applications
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NIR-II emitting fluorine-doped carbon dots with multi-enzyme mimic activities for NIR-II imaging and photothermal-enhanced cancer catalytic immunotherapy
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IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps
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MDSCs in liver cancer: A critical tumor-promoting player and a potential therapeutic target
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Tumor-related stress regulates functional plasticity of MDSCs
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Age-related and postmenopausal breast cancer progression and treatment management: The significance of pro-inflammatory cytokines and CXC chemokines
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Role of immune regulatory cells in breast cancer: Foe or friend?
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Administration of soluble gp130Fc disrupts M-1 macrophage polarization, dendritic cell activation, MDSC expansion and Th-17 induction during experimental cerebral malaria
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Disruption of CD47-SIRPα signaling restores inflammatory function in tumor-associated myeloid-derived suppressor cells
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New insight into the role of SOCS family in immune regulation and autoimmune pathogenesis
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IL-6 trans-signaling in cancer metabolism, multidrug resistance, and chronic inflammation
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Multifunctional ginsenoside Rg3-based liposomes for glioma targeting therapy
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Age-related expansion and increased osteoclastogenic potential of myeloid-derived suppressor cells
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Indoleamine 2,3-dioxygenase 1 regulates breast cancer tamoxifen resistance through interleukin-6/signal transducer and activator of transcription
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rPAC: Route based pathway analysis for cohorts of gene expression data sets
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In Situ Vaccination with Cowpea vs Tobacco Mosaic Virus against Melanoma
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Soluble receptors in cancer: mechanisms, clinical significance, and therapeutic strategies
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Cancer exosome-derived miR-9 and miR-181a promote the development of early-stage MDSCs via interfering with SOCS3 and PIAS3 respectively in breast cancer
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Incorporation of a Toll-like receptor 2/6 agonist potentiates mRNA vaccines against cancer and infectious diseases
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Immunosuppression mediated by myeloid-derived suppressor cells (MDSCs) during tumour progression
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CD45+CD33lowCD11bdim myeloid-derived suppressor cells suppress CD8+ T cell activity via the IL-6/IL-8-arginase I axis in human gastric cancer
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LncRNA SEMA3B-AS1 inhibits breast cancer progression by targeting miR-3940/KLLN axis
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Olfactory ecto-mesenchymal stem cell-derived exosomes ameliorate murine Sjögren’s syndrome by modulating the function of myeloid-derived suppressor cells
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Exportin 1 governs the immunosuppressive functions of myeloid-derived suppressor cells in tumors through ERK1/2 nuclear export
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Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis
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Targeting obesity and adipokine signaling in the breast cancer microenvironment for enhanced tumor therapy
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Systemic maternal inflammation promotes ASD via IL-6 and IFN-γ
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Upregulation of ADAM10 reinforces CD8 + T cells toward exhaustion in the TME
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The role of myeloid-derived suppressor cells in lung cancer and targeted immunotherapies
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Noncoding RNAs in inflammation and colorectal cancer
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Chronic stress promotes breast carcinoma metastasis by accumulating myeloid-derived suppressor cells through activating β-adrenergic signaling
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SOCS3 deficiency-dependent autophagy repression promotes the survival of early-stage myeloid-derived suppressor cells in breast cancer by activating the Wnt/mTOR pathway
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Interleukin-6 Drives Key Pathologic Outcomes in Experimental Acetaminophen-induced Liver Failure
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Emergency myelopoiesis in solid cancers
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Enhanced dual function of osteoclast precursors following calvarial Porphyromonas gingivalis infection
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Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model
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Timed adoptive T cell transfer during chemotherapy in patients with recurrent platinum-sensitive epithelial ovarian cancer
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Prospective Evaluation of Immune Activation Associated with Response to Radioembolization Assessed with PET/CT in Women with Breast Cancer Liver Metastasis
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Expression Analysis of the Mediators of Epithelial to Mesenchymal Transition and Early Risk Assessment of Therapeutic Failure in Laryngeal Carcinoma
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IL‐6 Promotes the Proliferation and Immunosuppressive Function of Myeloid‐Derived Suppressor Cells via the MAPK Signaling Pathway in Bladder Cancer
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PTPN18 Serves as a Potential Oncogene for Glioblastoma by Enhancing Immune Suppression
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Data from Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity
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Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity
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Targeted Inhibition of lncRNA Malat1 Alters the Tumor Immune Microenvironment in Preclinical Syngeneic Mouse Models of Triple-Negative Breast Cancer
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Ex Vivo–Induced Bone Marrow-Derived Myeloid Suppressor Cells Prevent Corneal Allograft Rejection in Mice
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YAP1 induces bladder cancer progression and promotes immune evasion through IL-6/STAT3 pathway and CXCL deregulation
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BRD4 inhibition leads to MDSC apoptosis and enhances checkpoint blockade therapy
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Cytokines in various molecular subtypes of breast cancer
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CCL2/CCR2 signaling in cancer pathogenesis
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Coordinated regulation of immune contexture: crosstalk between STAT3 and immune cells during breast cancer progression
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Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy
inferred← citeshttps://doi.org/10.1186/s13148-020-0808-9openalex-snapshot
Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer
inferred← citeshttps://doi.org/10.1186/s40364-021-00333-5openalex-snapshot
Landscape of Myeloid-derived Suppressor Cell in Tumor Immunotherapy
inferred← citeshttps://doi.org/10.1186/s40364-022-00415-yopenalex-snapshot
Direct and indirect effects of IFN-α2b in malignancy treatment: not only an archer but also an arrow
inferred← citeshttps://doi.org/10.1186/s40537-023-00752-1openalex-snapshot
Prognostic stratification based on HIF-1α signaling for evaluating hypoxia status and immune landscape in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1186/s43556-026-00586-2openalex-snapshot
Decoding neuro-tumor interactions in pancreatic cancer: mechanisms, immunosuppressive networks and therapeutic opportunities
inferred← citeshttps://doi.org/10.21037/tau-20-943openalex-snapshot
Myeloid-derived suppressor cell (MDSC) key genes analysis in rat anti-CD28-induced immune tolerance kidney transplantation
inferred← citeshttps://doi.org/10.2147/ijn.s191504openalex-snapshot
Curcumin nanoparticles are a promising anti-bacterial and anti-inflammatory agent for treating periprosthetic joint infections
inferred← citeshttps://doi.org/10.2174/0929867329666220324143215openalex-snapshot
Current Overview on the Potency of Natural Products for Modulating Myeloid-derived Suppressor Cells Dependent Cold Tumors
inferred← citeshttps://doi.org/10.2174/1871520623666230713101119openalex-snapshot
STAT3 Signaling Axis and Tamoxifen in Breast Cancer: A Promising Target for Treatment Resistance
inferred← citeshttps://doi.org/10.29245/2578-3009/2018/2.1135openalex-snapshot
Myeloid-derived suppressor cells and their "inconvenient" plasticity
inferred← citeshttps://doi.org/10.3389/fbioe.2022.973731openalex-snapshot
Early myeloid-derived suppressor cells accelerate epithelial-mesenchymal transition by downregulating ARID1A in luminal A breast cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2018.01699openalex-snapshot
SOCS3 Suppression Promoted the Recruitment of CD11b+Gr-1−F4/80−MHCII− Early-Stage Myeloid-Derived Suppressor Cells and Accelerated Interleukin-6-Related Tumor Invasion via Affecting Myeloid Differentiation in Breast Cancer
inferred← citeshttps://doi.org/10.3389/fimmu.2020.00737openalex-snapshot
The Emerging Role of Myeloid-Derived Suppressor Cells in the Glioma Immune Suppressive Microenvironment
inferred← citeshttps://doi.org/10.3389/fimmu.2021.612139openalex-snapshot
TANK-Binding Kinase 1 (TBK1) Serves as a Potential Target for Hepatocellular Carcinoma by Enhancing Tumor Immune Infiltration
inferred← citeshttps://doi.org/10.3389/fimmu.2021.649020openalex-snapshot
TRAF6 Regulates the Immunosuppressive Effects of Myeloid-Derived Suppressor Cells in Tumor-Bearing Host
inferred← citeshttps://doi.org/10.3389/fimmu.2021.658896openalex-snapshot
Cytokine Overproduction and Immune System Dysregulation in alloHSCT and COVID-19 Patients
inferred← citeshttps://doi.org/10.3389/fimmu.2021.661323openalex-snapshot
Tumor NLRP3-Derived IL-1β Drives the IL-6/STAT3 Axis Resulting in Sustained MDSC-Mediated Immunosuppression
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1016870openalex-snapshot
Epigenetic modifications in the accumulation and function of myeloid-derived suppressor cells
inferred← citeshttps://doi.org/10.3389/fimmu.2022.838990openalex-snapshot
JEV Infection Induces M-MDSC Differentiation Into CD3+ Macrophages in the Brain
inferred← citeshttps://doi.org/10.3389/fimmu.2022.929677openalex-snapshot
miR-aculous new avenues for cancer immunotherapy
inferred← citeshttps://doi.org/10.3389/fimmu.2023.1199273openalex-snapshot
MDSCs in breast cancer: an important enabler of tumor progression and an emerging therapeutic target
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1518664openalex-snapshot
NF-κB signaling and the tumor microenvironment in osteosarcoma: implications for immune evasion and therapeutic resistance
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1656733openalex-snapshot
Senescent immune cells in the tumor microenvironment: emerging insights into cancer immunotherapy resistance
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1660272openalex-snapshot
Mechanisms of immunotherapy in cutaneous squamous cell carcinoma in the tumor microenvironment
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1718894openalex-snapshot
“Brake” and “accelerator”: revisiting tumor cell direct responses and the paradox of aggression in anti-VEGF therapy
inferred← citeshttps://doi.org/10.3389/fonc.2019.01223openalex-snapshot
IL-6 and IL-8 Are Linked With Myeloid-Derived Suppressor Cell Accumulation and Correlate With Poor Clinical Outcomes in Melanoma Patients
inferred← citeshttps://doi.org/10.3389/fonc.2022.866014openalex-snapshot
IL-6/JAK/STAT3 Signaling in Breast Cancer Metastasis: Biology and Treatment
inferred← citeshttps://doi.org/10.3389/fonc.2026.1639330openalex-snapshot
Distinct protein and metabolic profiles in patients with advanced clear-cell renal cell carcinoma treated with sunitinib: a study of the Spanish oncology genitourinary group
inferred← citeshttps://doi.org/10.3389/fonc.2026.1861308openalex-snapshot
Cell competition within breast tumor microenvironment: emerging role of cancer stem cells and immune cells in tumor progression and therapeutic implications
inferred← citeshttps://doi.org/10.3389/fonc.2026.1947958openalex-snapshot
Obesity-driven inflammation and immune dysregulation in cancer development and progression
inferred← citeshttps://doi.org/10.3390/biom12020310openalex-snapshot
Discovering the Triad between Nav1.5, Breast Cancer, and the Immune System: A Fundamental Review and Future Perspectives
inferred← citeshttps://doi.org/10.3390/biomedicines9040374openalex-snapshot
Tumor-Associated Macrophages—Implications for Molecular Oncology and Imaging
inferred← citeshttps://doi.org/10.3390/cancers11111716openalex-snapshot
Balancing STAT Activity as a Therapeutic Strategy
inferred← citeshttps://doi.org/10.3390/cancers13071511openalex-snapshot
Targeting the IL-6/STAT3 Signalling Cascade to Reverse Tamoxifen Resistance in Estrogen Receptor Positive Breast Cancer
inferred← citeshttps://doi.org/10.3390/cancers14112756openalex-snapshot
The Role of Indoleamine 2, 3-Dioxygenase 1 in Regulating Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/cancers14143356openalex-snapshot
CISH Expression Is Associated with Metastasis-Free Interval in Triple-Negative Breast Cancer and Refines the Prognostic Value of PDL1 Expression
inferred← citeshttps://doi.org/10.3390/cancers15010082openalex-snapshot
Tumor-Derived Extracellular Vesicles in Cancer Immunoediting and Their Potential as Oncoimmunotherapeutics
inferred← citeshttps://doi.org/10.3390/cancers16162861openalex-snapshot
Unveiling the Dynamic Interplay between Cancer Stem Cells and the Tumor Microenvironment in Melanoma: Implications for Novel Therapeutic Strategies
inferred← citeshttps://doi.org/10.3390/cells10092245openalex-snapshot
Annexin A1 as a Regulator of Immune Response in Cancer
inferred← citeshttps://doi.org/10.3390/cells12151981openalex-snapshot
The Role of Cytokines in Neutrophil Development, Tissue Homing, Function and Plasticity in Health and Disease
inferred← citeshttps://doi.org/10.3390/cells13100795openalex-snapshot
Protein Signature Differentiating Neutrophils and Myeloid-Derived Suppressor Cells Determined Using a Human Isogenic Cell Line Model and Protein Profiling
inferred← citeshttps://doi.org/10.3390/cells9030615openalex-snapshot
Decoding the Role of Interleukin-30 in the Crosstalk between Cancer and Myeloid Cells
inferred← citeshttps://doi.org/10.3390/ijms221810009openalex-snapshot
Nanoparticles Targeting Innate Immune Cells in Tumor Microenvironment
inferred← citeshttps://doi.org/10.3390/ijms231810299openalex-snapshot
Th17, Th22, and Myeloid-Derived Suppressor Cell Population Dynamics and Response to IL-6 in 4T1 Mammary Carcinoma
inferred← citeshttps://doi.org/10.3390/ijms25116224openalex-snapshot
Guardians and Mediators of Metastasis: Exploring T Lymphocytes, Myeloid-Derived Suppressor Cells, and Tumor-Associated Macrophages in the Breast Cancer Microenvironment
inferred← citeshttps://doi.org/10.3892/mi.2024.170openalex-snapshot
Myeloid‑derived suppressor cells as targets of emerging therapies and nanotherapies (Review)
inferred← citeshttps://doi.org/10.3892/ol.2025.15006openalex-snapshot
Role of antidiarrheal agents nifuroxazide in antitumor multi‑target anticancer, multi‑mechanism anticancer drug (Review)
inferred← citeshttps://doi.org/10.4062/biomolther.2018.201openalex-snapshot
Analysis of the Expression and Regulation of PD-1 Protein on the Surface of Myeloid-Derived Suppressor Cells (MDSCs)
inferred← citeshttps://doi.org/10.6084/m9.figshare.26590793openalex-snapshot
Additional file 1 of Prognostic stratification based on HIF-1α signaling for evaluating hypoxia status and immune landscape in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.26590796openalex-snapshot
Additional file 2 of Prognostic stratification based on HIF-1α signaling for evaluating hypoxia status and immune landscape in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.26590799openalex-snapshot
Additional file 3 of Prognostic stratification based on HIF-1α signaling for evaluating hypoxia status and immune landscape in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.6084/m9.figshare.26590802openalex-snapshot
Additional file 4 of Prognostic stratification based on HIF-1α signaling for evaluating hypoxia status and immune landscape in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.61882/tcr.202501.02.06openalex-snapshot
The IL-6 Network in Multiple Myeloma: From Tumor Survival Pathways to Immune Dysfunction and Cytokine Storm in Modern Therapies
inferred← citeshttps://doi.org/10.70675/ede8abd2zb03az4e84zb2a0z9b6221997db2openalex-snapshot
Rôles directs d'une chimiothérapie et vésicules libérées par le cancer sur les déficits cognitifs et/ou émotionnels dans des modèles précliniques
inferred← citeshttps://doi.org/10.7150/ijbs.68865openalex-snapshot
Mannan-Binding Lectin Deficiency Limits Inflammation-induced Myeloid-Derived Suppressor Cells Expansion via Modulating Tumor Necrosis Factor Alpha-triggered Apoptosis
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