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CD160 Plays a Protective Role During Chronic Infection by Enhancing Both Functionalities and Proliferative Capacity of CD8+ T Cells

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/eji.200635935openalex-snapshot
The co‐expression of 2B4 (CD244) and CD160 delineates a subpopulation of human CD8+ T cells with a potent CD160‐mediated cytolytic effector function
inferredcites →https://doi.org/10.1002/eji.201747172openalex-snapshot
Mechanisms of CD8 + T cell‐mediated suppression of HIV/SIV replication
inferredcites →https://doi.org/10.1007/s11904-011-0106-4openalex-snapshot
Role of PD-1 in HIV Pathogenesis and as Target for Therapy
inferredcites →https://doi.org/10.1007/s12026-010-8177-7openalex-snapshot
CD8+T-cell-mediated control of HIV-1 and SIV infection
inferredcites →https://doi.org/10.1016/j.cellimm.2005.01.012openalex-snapshot
The CD160+ CD8high cytotoxic T cell subset correlates with response to HAART in HIV-1+ patients
inferredcites →https://doi.org/10.1016/j.immuni.2010.08.002openalex-snapshot
Differentiation and Persistence of Memory CD8+ T Cells Depend on T Cell Factor 1
inferredcites →https://doi.org/10.1016/j.immuni.2016.07.021openalex-snapshot
T Cell Factor 1-Expressing Memory-like CD8+ T Cells Sustain the Immune Response to Chronic Viral Infections
inferredcites →https://doi.org/10.1016/j.jviromet.2007.08.025openalex-snapshot
Quantitative PCR technique for detecting lymphocytic choriomeningitis virus in vivo
inferredcites →https://doi.org/10.1016/s0022-1759(03)00265-5openalex-snapshot
Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation
inferredcites →https://doi.org/10.1038/44385openalex-snapshot
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
inferredcites →https://doi.org/10.1038/nature04444openalex-snapshot
Restoring function in exhausted CD8 T cells during chronic viral infection
inferredcites →https://doi.org/10.1038/nature05115openalex-snapshot
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression
inferredcites →https://doi.org/10.1038/ni1515openalex-snapshot
Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction
inferredcites →https://doi.org/10.1038/ni1554openalex-snapshot
CD160 inhibits activation of human CD4+ T cells through interaction with herpesvirus entry mediator
inferredcites →https://doi.org/10.1038/nprot.2008.211openalex-snapshot
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
inferredcites →https://doi.org/10.1038/nri3862openalex-snapshot
Molecular and cellular insights into T cell exhaustion
inferredcites →https://doi.org/10.1038/s41467-019-10320-yopenalex-snapshot
CD160 serves as a negative regulator of NKT cells in acute hepatic injury
inferredcites →https://doi.org/10.1084/jem.20081398openalex-snapshot
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
inferredcites →https://doi.org/10.1084/jem.20131601openalex-snapshot
CD160 is essential for NK-mediated IFN-γ production
inferredcites →https://doi.org/10.1093/infdis/jiv226openalex-snapshot
Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8+T-Cell Population in Elite Controllers
inferredcites →https://doi.org/10.1093/intimm/14.5.445openalex-snapshot
BY55/CD160 acts as a co‐receptor in TCR signal transduction of a human circulating cytotoxic effector T lymphocyte subset lacking CD28 expression
inferredcites →https://doi.org/10.1093/nar/gkn923openalex-snapshot
Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists
inferredcites →https://doi.org/10.1111/j.1600-065x.2009.00783.xopenalex-snapshot
The CD160, BTLA, LIGHT/HVEM pathway: a bidirectional switch regulating T‐cell activation
inferredcites →https://doi.org/10.1126/science.aaf0683openalex-snapshot
Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent
inferredcites →https://doi.org/10.1146/annurev-immunol-041015-055318openalex-snapshot
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
inferredcites →https://doi.org/10.1182/blood-2006-09-044826openalex-snapshot
PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors
inferredcites →https://doi.org/10.1182/blood-2010-11-317297openalex-snapshot
Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection
inferredcites →https://doi.org/10.1371/journal.ppat.1002840openalex-snapshot
CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction
inferredcites →https://doi.org/10.3389/fimmu.2018.02611openalex-snapshot
HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage
inferredcites →https://doi.org/10.4049/immunohorizons.1800039openalex-snapshot
CD160 Stimulates CD8+ T Cell Responses and Is Required for Optimal Protective Immunity to Listeria monocytogenes
inferredcites →https://doi.org/10.4049/jimmunol.0804211openalex-snapshot
Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells
inferredcites →https://doi.org/10.4049/jimmunol.1402176openalex-snapshot
The Upregulation of LAG-3 on T Cells Defines a Subpopulation with Functional Exhaustion and Correlates with Disease Progression in HIV-Infected Subjects
inferredcites →https://doi.org/10.4049/jimmunol.161.6.2780openalex-snapshot
Cloning of BY55, a Novel Ig Superfamily Member Expressed on NK Cells, CTL, and Intestinal Intraepithelial Lymphocytes
inferredcites →https://doi.org/10.4049/jimmunol.162.3.1223openalex-snapshot
Cutting Edge: MHC Class I Triggering by a Novel Cell Surface Ligand Costimulates Proliferation of Activated Human T Cells
inferredcites →https://doi.org/10.4049/jimmunol.175.7.4426openalex-snapshot
Murine CD160, Ig-Like Receptor on NK Cells and NKT Cells, Recognizes Classical and Nonclassical MHC Class I and Regulates NK Cell Activation

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4687146openalex-extracted
Upregulated Circulating CD4 KLRD1 T Cells Exhibit Characteristics of CD4 Cytotoxic T Lymphocytes in Systemic Lupus Erythematosus Patients
inferred← citeshttps://doi.org/10.1007/s00253-021-11143-yopenalex-snapshot
The microbiome of bat guano: for what is this knowledge important?
inferred← citeshttps://doi.org/10.1007/s10238-023-01188-wopenalex-snapshot
The kinetics of inhibitory immune checkpoints during and post-COVID-19: the knowns and unknowns
inferred← citeshttps://doi.org/10.1016/j.bbcan.2025.189421openalex-snapshot
From infection to immune exhaustion: The Epstein-Barr virus and its contribution to Immunosenescence
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113694openalex-snapshot
CD160 protein as a new therapeutic target in a battle against autoimmune, infectious and lifestyle diseases. Analysis of the structure, interactions and functions
inferred← citeshttps://doi.org/10.1016/j.mcpro.2026.101644openalex-snapshot
Proteomic Insights Into Human Induced Regulatory T Cells: The Role of LPXN and CD160 in Immune Suppression
inferred← citeshttps://doi.org/10.1016/j.trsl.2021.08.006openalex-snapshot
The impact of CD160 deficiency on alloreactive CD8 T cell responses and allograft rejection
inferred← citeshttps://doi.org/10.1038/s41419-025-07717-7openalex-snapshot
Application of imaging mass cytometry for spatially profiling the microenvironment of salivary glands in primary Sjögren’s syndrome
inferred← citeshttps://doi.org/10.1038/s41556-025-01753-3openalex-snapshot
CD160 dictates anti-PD-1 immunotherapy resistance by regulating CD8+ T cell exhaustion in colorectal cancer
inferred← citeshttps://doi.org/10.1038/s41598-024-51536-3openalex-snapshot
Development of macrophage-associated genes prognostic signature predicts clinical outcome and immune infiltration for sepsis
inferred← citeshttps://doi.org/10.1080/09273948.2023.2217906openalex-snapshot
CD8+ T–cell Exhaustion Phenotype in Human Asymptomatic and Ocular Toxoplasmosis
inferred← citeshttps://doi.org/10.1097/shk.0000000000002115openalex-snapshot
SCREENING OF POTENTIAL CORE GENES IN THE PERIPHERAL BLOOD OF ADULT PATIENTS WITH SEPSIS BASED ON IMMUNOREGULATION AND SIGNAL TRANSDUCTION FUNCTIONS
inferred← citeshttps://doi.org/10.1111/cas.15804openalex-snapshot
Plasma extracellular vesicle transcriptomics identifies CD160 for predicting immunochemotherapy efficacy in lung cancer
inferred← citeshttps://doi.org/10.1126/sciimmunol.adk2954openalex-snapshot
The redox sensor KEAP1 facilitates adaptation of T cells to chronic antigen stimulation by preventing hyperactivation
inferred← citeshttps://doi.org/10.1128/jvi.01259-21openalex-snapshot
Collaboration of a Detrimental HLA-B*35:01 Allele with HLA-A*24:02 in Coevolution of HIV-1 with T Cells Leading to Poorer Clinical Outcomes
inferred← citeshttps://doi.org/10.1182/blood.2021013290openalex-snapshot
Blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia
inferred← citeshttps://doi.org/10.32469/10355/88918openalex-snapshot
Virus interactions with the sphingolipid network : sphingosine kinase 2 in immunosuppression, immunopathology, and viral propagation
inferred← citeshttps://doi.org/10.3389/fimmu.2021.771279openalex-snapshot
Hsa-miR-31 Governs T-Cell Homeostasis in HIV Protection via IFN-γ-Stat1-T-Bet Axis
inferred← citeshttps://doi.org/10.3389/fimmu.2022.1028013openalex-snapshot
CD160 receptor in CLL: Current state and future avenues
inferred← citeshttps://doi.org/10.3389/fimmu.2022.854432openalex-snapshot
CD160 Promotes NK Cell Functions by Upregulating Glucose Metabolism and Negatively Correlates With HIV Disease Progression
inferred← citeshttps://doi.org/10.3389/fimmu.2026.1782124openalex-snapshot
The CD160–HVEM axis at the crossroads of tolerance and immunity: lessons from cancer for autoimmunity and transplantation
inferred← citeshttps://doi.org/10.3389/fviro.2022.836291openalex-snapshot
The Role of the Inhibitory Ligand HVEM and Its Receptors CD160 and BTLA in the Regulation of Anti-retroviral T Cell Responses
inferred← citeshttps://doi.org/10.3390/jcm14145139openalex-snapshot
Differential Role of CD318 in Tumor Immunity Affecting Prognosis in Colorectal Cancer Compared to Other Adenocarcinomas
inferred← citeshttps://doi.org/10.3390/v14030581openalex-snapshot
Expression Profile and Biological Role of Immune Checkpoints in Disease Progression of HIV/SIV Infection
inferred← citeshttps://doi.org/10.4049/jimmunol.2200792openalex-snapshot
CD160 Signaling Is Essential for CD8+ T Cell Memory Formation via Upregulation of 4-1BB
inferred← citeshttps://doi.org/10.4049/jimmunol.2300742openalex-snapshot
Virus-specific Th17 Cells Are Induced by Human Cytomegalovirus after Renal Transplantation
inferred← citeshttps://doi.org/10.70675/4e035d32zbda7z4539z8911z00e1344b619fopenalex-snapshot
Etude de CD160, récepteur activateur des cellules NK dans le mélanome : une potentielle cible thérapeutique à l'ère de l'immunothérapie ?
inferred← citeshttps://doi.org/10.70675/d7776aeezbb6dz472cz95daze909026fb2ebopenalex-snapshot
Expression du récepteur CD160 par les cancers du sein : caractérisation fonctionnelle et applications thérapeutiques potentielles
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